Calcium in PDB 5z4p: Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex

The structure of Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex, PDB code: 5z4p was solved by H.Zhang, C.Luo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.64 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	103.832, 154.843, 181.024, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 28.6

The structure of Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Calcium atom in the Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex (pdb code 5z4p). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex, PDB code: 5z4p:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca505 b:82.8 occ:1.00 OE1 A:GLU55 2.3 73.6 1.0 O A:THR41 2.3 75.0 1.0 OD2 A:ASP39 2.4 71.8 1.0 OG1 A:THR41 2.4 87.1 1.0 OD1 A:ASP39 2.5 67.9 1.0 O A:GLY44 2.6 69.7 1.0 CG A:ASP39 2.8 70.2 1.0 OE2 A:GLU55 2.9 75.4 1.0 CD A:GLU55 2.9 75.1 1.0 C A:THR41 3.4 80.0 1.0 CB A:THR41 3.5 77.5 1.0 C A:GLY44 3.7 70.3 1.0 CA A:THR41 3.8 78.5 1.0 CZ A:PHE49 3.9 71.3 1.0 N A:THR41 4.1 77.3 1.0 CA A:GLY45 4.2 77.2 1.0 NE2 A:HIS61 4.2 65.3 1.0 OD1 A:ASN50 4.2 74.7 1.0 CB A:ASP39 4.3 69.2 1.0 N A:GLY45 4.4 72.5 1.0 CG A:GLU55 4.4 72.4 1.0 N A:GLY44 4.4 79.8 1.0 ND2 A:ASN50 4.5 72.7 1.0 CE2 A:PHE49 4.5 73.4 1.0 OD2 A:ASP47 4.5 75.6 1.0 N A:ILE42 4.5 74.1 1.0 CA A:GLY44 4.7 78.3 1.0 CG2 A:THR41 4.8 69.0 1.0 CE1 A:PHE49 4.8 69.1 1.0 CG A:ASN50 4.8 70.5 1.0 N A:GLY43 5.0 75.7 1.0

Calcium binding site 2 out of 3 in the Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca504 b:97.8 occ:1.00 OE1 B:GLU113 2.8 74.4 1.0 OE2 B:GLU110 3.2 44.0 1.0 CD B:GLU113 3.9 65.7 1.0 CD B:GLU110 3.9 60.6 1.0 OE1 B:GLU110 4.0 61.5 1.0 OE2 B:GLU113 4.3 77.1 1.0 OG B:SER97 4.5 71.0 1.0

Calcium binding site 3 out of 3 in the Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Tubulin-Stathmin-Ttl-Compound Tca Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca508 b:86.0 occ:1.00 O C:TYR282 3.7 61.7 1.0 O C:GLU279 4.4 62.7 1.0 O C:LYS280 4.4 65.7 1.0 C C:TYR282 4.9 61.2 1.0 CD C:LYS280 5.0 63.7 1.0 CB C:HIS283 5.0 64.7 1.0

H.Zhang, C.Luo. Discovery and Design of Novel Tubulin Inhibitors To Be Published.