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Atomistry » Calcium » PDB 6tz7-6ul8 » 6tz7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 6tz7-6ul8 » 6tz7 » |
Calcium in PDB 6tz7: Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)Enzymatic activity of Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
All present enzymatic activity of Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus):
3.1.3.16; 5.2.1.8; Protein crystallography data
The structure of Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus), PDB code: 6tz7
was solved by
D.Fox Iii,
P.S.Horanyi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6tz7:
The structure of Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
(pdb code 6tz7). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus), PDB code: 6tz7: Jump to Calcium binding site number: 1; 2; 3; Calcium binding site 1 out of 3 in 6tz7Go back to Calcium Binding Sites List in 6tz7
Calcium binding site 1 out
of 3 in the Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
Mono view Stereo pair view
Calcium binding site 2 out of 3 in 6tz7Go back to Calcium Binding Sites List in 6tz7
Calcium binding site 2 out
of 3 in the Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
Mono view Stereo pair view
Calcium binding site 3 out of 3 in 6tz7Go back to Calcium Binding Sites List in 6tz7
Calcium binding site 3 out
of 3 in the Crystal Structure of Aspergillus Fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
Mono view Stereo pair view
Reference:
P.R.Juvvadi,
D.Fox 3Rd,
B.G.Bobay,
M.J.Hoy,
S.M.C.Gobeil,
R.A.Venters,
Z.Chang,
J.J.Lin,
A.F.Averette,
D.C.Cole,
B.C.Barrington,
J.D.Wheaton,
M.Ciofani,
M.Trzoss,
X.Li,
S.C.Lee,
Y.L.Chen,
M.Mutz,
L.D.Spicer,
M.A.Schumacher,
J.Heitman,
W.J.Steinbach.
Harnessing Calcineurin-FK506-FKBP12 Crystal Structures From Invasive Fungal Pathogens to Develop Antifungal Agents. Nat Commun V. 10 4275 2019.
Page generated: Tue Jul 16 15:39:41 2024
ISSN: ESSN 2041-1723 PubMed: 31537789 DOI: 10.1038/S41467-019-12199-1 |
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