Calcium in PDB 6xqo: Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc

The binding sites of Calcium atom in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc (pdb code 6xqo). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc, PDB code: 6xqo:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ I:Ca501 b:90.5 occ:1.00 OD1 I:ASN233 2.4 89.2 1.0 OE2 I:GLU242 2.5 89.3 1.0 ND2 I:ASN233 2.5 89.2 1.0 O I:GLU237 2.5 91.4 1.0 OD1 I:ASP235 2.6 90.2 1.0 OD1 I:ASP231 2.7 82.7 1.0 CG I:ASN233 2.7 89.2 1.0 CG I:ASP235 3.3 90.2 1.0 C I:GLU237 3.4 91.4 1.0 CD I:GLU242 3.4 89.3 1.0 CG I:ASP231 3.6 82.7 1.0 OE1 I:GLU242 3.7 89.3 1.0 CA I:VAL238 3.8 85.1 1.0 OD2 I:ASP235 3.8 90.2 1.0 N I:VAL238 4.0 85.1 1.0 CB I:ASN233 4.2 89.2 1.0 N I:ASP239 4.3 89.3 1.0 OD2 I:ASP231 4.3 82.7 1.0 CB I:ASP235 4.3 90.2 1.0 N I:GLU237 4.3 91.4 1.0 C I:VAL238 4.4 85.1 1.0 N I:ASP235 4.5 90.2 1.0 CA I:GLU237 4.5 91.4 1.0 CB I:ASP231 4.5 82.7 1.0 CA I:ASP231 4.6 82.7 1.0 N I:ASN233 4.6 89.2 1.0 N I:GLY234 4.8 89.8 1.0 CG I:GLU242 4.8 89.3 1.0 CG2 I:VAL238 4.9 85.1 1.0 N I:GLY236 4.9 89.8 1.0 CA I:ASN233 4.9 89.2 1.0 CA I:ASP235 4.9 90.2 1.0 CB I:VAL238 4.9 85.1 1.0

Calcium binding site 2 out of 4 in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ I:Ca502 b:96.8 occ:1.00 OD1 I:ASN425 2.0 99.1 1.0 OD2 I:ASP423 2.2 0.8 1.0 OE2 I:GLU432 2.3 93.9 1.0 ND2 I:ASN425 2.5 99.1 1.0 CG I:ASN425 2.5 99.1 1.0 O I:GLU427 2.5 92.0 1.0 OD1 I:ASP421 2.6 0.1 1.0 OE1 I:GLU432 2.8 93.9 1.0 CD I:GLU432 2.9 93.9 1.0 CG I:ASP423 3.0 0.8 1.0 OD1 I:ASP423 3.2 0.8 1.0 CG I:ASP421 3.5 0.1 1.0 C I:GLU427 3.7 92.0 1.0 CB I:ASN425 4.0 99.1 1.0 OD2 I:ASP421 4.2 0.1 1.0 N I:ASN425 4.2 99.1 1.0 CA I:LEU428 4.3 90.2 1.0 CG I:GLU432 4.4 93.9 1.0 N I:LEU428 4.4 90.2 1.0 N I:GLU427 4.5 92.0 1.0 CB I:ASP423 4.5 0.8 1.0 CB I:ASP421 4.5 0.1 1.0 CA I:ASP421 4.6 0.1 1.0 N I:SER429 4.6 91.2 1.0 CA I:ASN425 4.6 99.1 1.0 N I:ASP423 4.6 0.8 1.0 CA I:GLU427 4.7 92.0 1.0 N I:GLY424 4.8 0.5 1.0 C I:LEU428 4.8 90.2 1.0 CA I:ASP423 4.9 0.8 1.0 N I:GLY426 4.9 92.6 1.0 C I:ASP421 5.0 0.1 1.0 C I:ASP423 5.0 0.8 1.0

Calcium binding site 3 out of 4 in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ J:Ca501 b:86.7 occ:1.00 OD1 J:ASN189 2.1 84.1 1.0 O J:MET191 2.2 81.7 1.0 OE1 J:GLU196 2.2 82.0 1.0 OD1 J:ASP187 2.6 83.5 1.0 CG J:ASN189 3.0 84.1 1.0 OD1 J:ASP185 3.0 79.8 1.0 CD J:GLU196 3.0 82.0 1.0 ND2 J:ASN189 3.2 84.1 1.0 CG J:GLU196 3.3 82.0 1.0 C J:MET191 3.4 81.7 1.0 CG J:ASP187 3.6 83.5 1.0 OD2 J:ASP187 3.9 83.5 1.0 CG J:GLU193 4.0 82.8 1.0 CG J:ASP185 4.0 79.8 1.0 N J:GLU193 4.1 82.8 1.0 OE2 J:GLU196 4.1 82.0 1.0 CA J:ILE192 4.2 80.0 1.0 N J:ILE192 4.2 80.0 1.0 OE2 J:GLU193 4.2 82.8 1.0 CB J:ASN189 4.4 84.1 1.0 N J:MET191 4.4 81.7 1.0 CA J:MET191 4.4 81.7 1.0 CB J:GLU196 4.4 82.0 1.0 N J:ASN189 4.4 84.1 1.0 CD J:GLU193 4.5 82.8 1.0 CA J:ASP185 4.5 79.8 1.0 CB J:ASP185 4.6 79.8 1.0 C J:ILE192 4.7 80.0 1.0 CB J:ASP187 4.8 83.5 1.0 CB J:MET191 4.8 81.7 1.0 CA J:ASN189 4.9 84.1 1.0 OD2 J:ASP185 4.9 79.8 1.0 N J:GLY188 4.9 83.2 1.0 N J:ASP187 4.9 83.5 1.0 CB J:GLU193 5.0 82.8 1.0

Calcium binding site 4 out of 4 in the Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of the Human MICU1-MICU2 Heterodimer, Calcium Bound, in Association with A Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ J:Ca502 b:0.6 occ:1.00 O J:CYS381 2.3 99.6 1.0 OD1 J:ASP377 2.3 0.8 1.0 OE1 J:GLU386 2.4 0.3 1.0 OD1 J:ASP379 2.4 1.0 1.0 OD2 J:ASP377 2.5 0.8 1.0 CG J:ASP377 2.7 0.8 1.0 OD2 J:ASP379 2.8 1.0 1.0 CG J:ASP379 3.0 1.0 1.0 CD J:GLU386 3.1 0.3 1.0 OE2 J:GLU386 3.1 0.3 1.0 OD1 J:ASP375 3.2 0.6 1.0 C J:CYS381 3.3 99.6 1.0 CA J:LEU382 3.6 98.5 1.0 C J:LEU382 3.8 98.5 1.0 N J:LEU382 3.8 98.5 1.0 N J:SER383 4.1 0.8 1.0 CB J:ASP377 4.2 0.8 1.0 O J:LEU382 4.4 98.5 1.0 N J:CYS381 4.4 99.6 1.0 CG J:ASP375 4.4 0.6 1.0 CB J:ASP379 4.5 1.0 1.0 CA J:CYS381 4.5 99.6 1.0 CG J:GLU386 4.5 0.3 1.0 N J:ASP379 4.7 1.0 1.0 N J:ASP377 4.8 0.8 1.0 CB J:SER383 4.8 0.8 1.0 CB J:LEU382 4.9 98.5 1.0 SG J:CYS381 4.9 99.6 1.0 CA J:ASP377 5.0 0.8 1.0

C.Wang, A.Jacewicz, B.D.Delgado, R.Baradaran, S.B.Long. Structures Reveal Gatekeeping of the Mitochondrial Ca 2+ Uniporter By MICU1-MICU2. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 32667285
DOI: 10.7554/ELIFE.59991