Calcium in PDB 7pxe: CA2+ Bound Drosophila Slo Channel
Other elements in 7pxe:
The structure of CA2+ Bound Drosophila Slo Channel also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the CA2+ Bound Drosophila Slo Channel
(pdb code 7pxe). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
CA2+ Bound Drosophila Slo Channel, PDB code: 7pxe:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 1 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1201
b:63.5
occ:1.00
|
O
|
A:GLN977
|
2.4
|
64.1
|
1.0
|
OD1
|
A:ASP983
|
2.4
|
77.3
|
1.0
|
O
|
A:ASP980
|
2.4
|
70.1
|
1.0
|
O
|
C:HOH1304
|
2.4
|
69.6
|
1.0
|
OD1
|
A:ASP985
|
2.5
|
77.3
|
1.0
|
OD1
|
C:ASN463
|
2.6
|
59.4
|
1.0
|
OD2
|
A:ASP985
|
2.6
|
77.3
|
1.0
|
CG
|
A:ASP985
|
2.9
|
77.3
|
1.0
|
O
|
A:HOH1302
|
3.2
|
69.2
|
1.0
|
CG
|
A:ASP983
|
3.3
|
77.3
|
1.0
|
C
|
A:ASP980
|
3.5
|
70.1
|
1.0
|
C
|
A:GLN977
|
3.5
|
64.1
|
1.0
|
CG
|
C:ASN463
|
3.5
|
59.4
|
1.0
|
OD2
|
A:ASP983
|
3.6
|
77.3
|
1.0
|
ND2
|
C:ASN463
|
3.8
|
59.4
|
1.0
|
O
|
A:ASP983
|
4.1
|
77.3
|
1.0
|
CA
|
A:GLN977
|
4.2
|
64.1
|
1.0
|
N
|
A:GLN981
|
4.3
|
72.4
|
1.0
|
CA
|
A:ASP980
|
4.3
|
70.1
|
1.0
|
CB
|
A:ASP985
|
4.4
|
77.3
|
1.0
|
N
|
A:ASP980
|
4.4
|
70.1
|
1.0
|
CA
|
A:GLN981
|
4.4
|
72.4
|
1.0
|
CB
|
A:ASP980
|
4.6
|
70.1
|
1.0
|
N
|
A:PHE978
|
4.6
|
61.3
|
1.0
|
C
|
A:ASP983
|
4.7
|
77.3
|
1.0
|
CB
|
A:ASP983
|
4.7
|
77.3
|
1.0
|
C
|
A:GLN981
|
4.7
|
72.4
|
1.0
|
CB
|
A:GLN977
|
4.7
|
64.1
|
1.0
|
O
|
A:GLN981
|
4.8
|
72.4
|
1.0
|
O
|
A:HOH1324
|
4.8
|
66.1
|
1.0
|
CA
|
A:PHE978
|
4.8
|
61.3
|
1.0
|
N
|
A:ASP983
|
4.9
|
77.3
|
1.0
|
CB
|
C:ASN463
|
4.9
|
59.4
|
1.0
|
CA
|
A:ASP983
|
5.0
|
77.3
|
1.0
|
|
Calcium binding site 2 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 2 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1202
b:62.4
occ:1.00
|
O
|
A:ARG528
|
2.4
|
68.5
|
1.0
|
O
|
A:GLN616
|
2.4
|
67.3
|
1.0
|
OE1
|
A:GLU550
|
2.5
|
65.7
|
1.0
|
O
|
A:GLY548
|
2.5
|
64.2
|
1.0
|
OD2
|
A:ASP381
|
2.8
|
73.5
|
1.0
|
OE2
|
A:GLU550
|
2.9
|
65.7
|
1.0
|
CD
|
A:GLU550
|
3.0
|
65.7
|
1.0
|
CG
|
A:ASP381
|
3.4
|
73.5
|
1.0
|
C
|
A:ARG528
|
3.5
|
68.5
|
1.0
|
C
|
A:GLY548
|
3.6
|
64.2
|
1.0
|
C
|
A:GLN616
|
3.6
|
67.3
|
1.0
|
CB
|
A:ASP381
|
4.1
|
73.5
|
1.0
|
CA
|
A:GLY548
|
4.1
|
64.2
|
1.0
|
OD1
|
A:ASP381
|
4.1
|
73.5
|
1.0
|
CA
|
A:SER529
|
4.3
|
76.5
|
1.0
|
OH
|
A:TYR552
|
4.3
|
67.2
|
1.0
|
N
|
A:SER529
|
4.3
|
76.5
|
1.0
|
N
|
A:ARG528
|
4.3
|
68.5
|
1.0
|
NE2
|
A:GLN616
|
4.3
|
67.3
|
1.0
|
CA
|
A:GLN616
|
4.4
|
67.3
|
1.0
|
CG
|
A:GLU550
|
4.5
|
65.7
|
1.0
|
CA
|
A:ARG528
|
4.5
|
68.5
|
1.0
|
N
|
A:SER617
|
4.6
|
71.3
|
1.0
|
N
|
A:MET549
|
4.7
|
66.3
|
1.0
|
CA
|
A:SER617
|
4.7
|
71.3
|
1.0
|
CB
|
A:SER617
|
5.0
|
71.3
|
1.0
|
CA
|
A:MET549
|
5.0
|
66.3
|
1.0
|
|
Calcium binding site 3 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 3 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1201
b:64.6
occ:1.00
|
O
|
B:GLN977
|
2.4
|
64.2
|
1.0
|
OD1
|
B:ASP983
|
2.4
|
77.2
|
1.0
|
O
|
B:ASP980
|
2.4
|
70.1
|
1.0
|
O
|
B:HOH1306
|
2.4
|
69.9
|
1.0
|
OD1
|
B:ASP985
|
2.5
|
77.7
|
1.0
|
OD1
|
D:ASN463
|
2.5
|
60.4
|
1.0
|
OD2
|
B:ASP985
|
2.6
|
77.7
|
1.0
|
CG
|
B:ASP985
|
2.9
|
77.7
|
1.0
|
O
|
B:HOH1302
|
3.2
|
68.3
|
1.0
|
CG
|
B:ASP983
|
3.3
|
77.2
|
1.0
|
CG
|
D:ASN463
|
3.4
|
60.4
|
1.0
|
C
|
B:ASP980
|
3.5
|
70.1
|
1.0
|
C
|
B:GLN977
|
3.5
|
64.2
|
1.0
|
OD2
|
B:ASP983
|
3.6
|
77.2
|
1.0
|
ND2
|
D:ASN463
|
3.7
|
60.4
|
1.0
|
O
|
B:ASP983
|
4.1
|
77.2
|
1.0
|
CA
|
B:GLN977
|
4.2
|
64.2
|
1.0
|
N
|
B:GLN981
|
4.3
|
72.7
|
1.0
|
CA
|
B:ASP980
|
4.3
|
70.1
|
1.0
|
CB
|
B:ASP985
|
4.4
|
77.7
|
1.0
|
N
|
B:ASP980
|
4.4
|
70.1
|
1.0
|
CA
|
B:GLN981
|
4.4
|
72.7
|
1.0
|
CB
|
B:ASP980
|
4.6
|
70.1
|
1.0
|
N
|
B:PHE978
|
4.6
|
61.3
|
1.0
|
C
|
B:ASP983
|
4.7
|
77.2
|
1.0
|
CB
|
B:ASP983
|
4.7
|
77.2
|
1.0
|
C
|
B:GLN981
|
4.7
|
72.7
|
1.0
|
CB
|
B:GLN977
|
4.7
|
64.2
|
1.0
|
O
|
B:GLN981
|
4.8
|
72.7
|
1.0
|
O
|
B:HOH1326
|
4.8
|
65.9
|
1.0
|
CB
|
D:ASN463
|
4.8
|
60.4
|
1.0
|
O
|
D:ASN463
|
4.8
|
60.4
|
1.0
|
CA
|
B:PHE978
|
4.8
|
61.3
|
1.0
|
N
|
B:ASP983
|
4.9
|
77.2
|
1.0
|
CA
|
B:ASP983
|
5.0
|
77.2
|
1.0
|
|
Calcium binding site 4 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 4 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1202
b:62.6
occ:1.00
|
O
|
B:ARG528
|
2.4
|
68.2
|
1.0
|
O
|
B:GLN616
|
2.4
|
67.8
|
1.0
|
OE1
|
B:GLU550
|
2.5
|
65.7
|
1.0
|
O
|
B:GLY548
|
2.5
|
64.4
|
1.0
|
OD2
|
B:ASP381
|
2.8
|
74.0
|
1.0
|
OE2
|
B:GLU550
|
2.9
|
65.7
|
1.0
|
CD
|
B:GLU550
|
3.0
|
65.7
|
1.0
|
CG
|
B:ASP381
|
3.4
|
74.0
|
1.0
|
C
|
B:ARG528
|
3.5
|
68.2
|
1.0
|
C
|
B:GLY548
|
3.6
|
64.4
|
1.0
|
C
|
B:GLN616
|
3.6
|
67.8
|
1.0
|
CB
|
B:ASP381
|
4.1
|
74.0
|
1.0
|
CA
|
B:GLY548
|
4.1
|
64.4
|
1.0
|
OD1
|
B:ASP381
|
4.1
|
74.0
|
1.0
|
CA
|
B:SER529
|
4.3
|
77.7
|
1.0
|
OH
|
B:TYR552
|
4.3
|
66.8
|
1.0
|
N
|
B:SER529
|
4.3
|
77.7
|
1.0
|
N
|
B:ARG528
|
4.3
|
68.2
|
1.0
|
NE2
|
B:GLN616
|
4.3
|
67.8
|
1.0
|
CA
|
B:GLN616
|
4.4
|
67.8
|
1.0
|
CG
|
B:GLU550
|
4.5
|
65.7
|
1.0
|
CA
|
B:ARG528
|
4.5
|
68.2
|
1.0
|
N
|
B:SER617
|
4.6
|
71.1
|
1.0
|
N
|
B:MET549
|
4.7
|
65.9
|
1.0
|
CA
|
B:SER617
|
4.7
|
71.1
|
1.0
|
CB
|
B:SER617
|
5.0
|
71.1
|
1.0
|
CA
|
B:MET549
|
5.0
|
65.9
|
1.0
|
|
Calcium binding site 5 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 5 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1201
b:62.3
occ:1.00
|
O
|
C:GLN977
|
2.4
|
64.2
|
1.0
|
OD1
|
C:ASP983
|
2.4
|
77.3
|
1.0
|
O
|
C:ASP980
|
2.4
|
70.5
|
1.0
|
O
|
C:HOH1303
|
2.4
|
70.0
|
1.0
|
OD1
|
C:ASP985
|
2.5
|
76.8
|
1.0
|
OD1
|
B:ASN463
|
2.5
|
59.8
|
1.0
|
OD2
|
C:ASP985
|
2.6
|
76.8
|
1.0
|
CG
|
C:ASP985
|
2.9
|
76.8
|
1.0
|
O
|
C:HOH1302
|
3.2
|
69.3
|
1.0
|
CG
|
C:ASP983
|
3.3
|
77.3
|
1.0
|
CG
|
B:ASN463
|
3.4
|
59.8
|
1.0
|
C
|
C:ASP980
|
3.5
|
70.5
|
1.0
|
C
|
C:GLN977
|
3.5
|
64.2
|
1.0
|
OD2
|
C:ASP983
|
3.6
|
77.3
|
1.0
|
ND2
|
B:ASN463
|
3.8
|
59.8
|
1.0
|
O
|
C:ASP983
|
4.1
|
77.3
|
1.0
|
CA
|
C:GLN977
|
4.1
|
64.2
|
1.0
|
N
|
C:GLN981
|
4.3
|
73.0
|
1.0
|
CA
|
C:ASP980
|
4.3
|
70.5
|
1.0
|
CB
|
C:ASP985
|
4.4
|
76.8
|
1.0
|
N
|
C:ASP980
|
4.4
|
70.5
|
1.0
|
CA
|
C:GLN981
|
4.4
|
73.0
|
1.0
|
CB
|
C:ASP980
|
4.6
|
70.5
|
1.0
|
N
|
C:PHE978
|
4.6
|
61.8
|
1.0
|
C
|
C:ASP983
|
4.7
|
77.3
|
1.0
|
CB
|
C:ASP983
|
4.7
|
77.3
|
1.0
|
C
|
C:GLN981
|
4.7
|
73.0
|
1.0
|
CB
|
C:GLN977
|
4.7
|
64.2
|
1.0
|
O
|
C:GLN981
|
4.8
|
73.0
|
1.0
|
CB
|
B:ASN463
|
4.8
|
59.8
|
1.0
|
O
|
C:HOH1327
|
4.8
|
65.2
|
1.0
|
CA
|
C:PHE978
|
4.8
|
61.8
|
1.0
|
N
|
C:ASP983
|
4.9
|
77.3
|
1.0
|
CA
|
C:ASP983
|
5.0
|
77.3
|
1.0
|
|
Calcium binding site 6 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 6 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1202
b:62.9
occ:1.00
|
O
|
C:ARG528
|
2.4
|
68.6
|
1.0
|
O
|
C:GLN616
|
2.4
|
67.8
|
1.0
|
OE1
|
C:GLU550
|
2.5
|
65.9
|
1.0
|
O
|
C:GLY548
|
2.5
|
64.2
|
1.0
|
OD2
|
C:ASP381
|
2.8
|
74.5
|
1.0
|
OE2
|
C:GLU550
|
2.9
|
65.9
|
1.0
|
CD
|
C:GLU550
|
3.0
|
65.9
|
1.0
|
CG
|
C:ASP381
|
3.4
|
74.5
|
1.0
|
C
|
C:ARG528
|
3.5
|
68.6
|
1.0
|
C
|
C:GLY548
|
3.6
|
64.2
|
1.0
|
C
|
C:GLN616
|
3.6
|
67.8
|
1.0
|
CB
|
C:ASP381
|
4.1
|
74.5
|
1.0
|
CA
|
C:GLY548
|
4.1
|
64.2
|
1.0
|
OD1
|
C:ASP381
|
4.1
|
74.5
|
1.0
|
CA
|
C:SER529
|
4.3
|
78.1
|
1.0
|
OH
|
C:TYR552
|
4.3
|
67.5
|
1.0
|
N
|
C:SER529
|
4.3
|
78.1
|
1.0
|
N
|
C:ARG528
|
4.3
|
68.6
|
1.0
|
NE2
|
C:GLN616
|
4.3
|
67.8
|
1.0
|
CA
|
C:GLN616
|
4.4
|
67.8
|
1.0
|
CG
|
C:GLU550
|
4.5
|
65.9
|
1.0
|
CA
|
C:ARG528
|
4.5
|
68.6
|
1.0
|
N
|
C:SER617
|
4.6
|
71.5
|
1.0
|
N
|
C:MET549
|
4.7
|
65.9
|
1.0
|
CA
|
C:SER617
|
4.7
|
71.5
|
1.0
|
CB
|
C:SER617
|
5.0
|
71.5
|
1.0
|
CA
|
C:MET549
|
5.0
|
65.9
|
1.0
|
|
Calcium binding site 7 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 7 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca1201
b:66.3
occ:1.00
|
O
|
D:GLN977
|
2.4
|
64.3
|
1.0
|
OD1
|
D:ASP983
|
2.4
|
78.1
|
1.0
|
O
|
D:ASP980
|
2.4
|
70.7
|
1.0
|
O
|
D:HOH1310
|
2.4
|
71.2
|
1.0
|
OD1
|
D:ASP985
|
2.5
|
78.7
|
1.0
|
OD2
|
D:ASP985
|
2.6
|
78.7
|
1.0
|
OD1
|
A:ASN463
|
2.7
|
59.5
|
1.0
|
CG
|
D:ASP985
|
2.9
|
78.7
|
1.0
|
O
|
D:HOH1302
|
3.2
|
68.1
|
1.0
|
CG
|
D:ASP983
|
3.3
|
78.1
|
1.0
|
C
|
D:ASP980
|
3.5
|
70.7
|
1.0
|
C
|
D:GLN977
|
3.5
|
64.3
|
1.0
|
OD2
|
D:ASP983
|
3.6
|
78.1
|
1.0
|
CG
|
A:ASN463
|
3.7
|
59.5
|
1.0
|
ND2
|
A:ASN463
|
3.9
|
59.5
|
1.0
|
O
|
D:ASP983
|
4.1
|
78.1
|
1.0
|
CA
|
D:GLN977
|
4.2
|
64.3
|
1.0
|
N
|
D:GLN981
|
4.3
|
73.7
|
1.0
|
CA
|
D:ASP980
|
4.3
|
70.7
|
1.0
|
CB
|
D:ASP985
|
4.4
|
78.7
|
1.0
|
N
|
D:ASP980
|
4.4
|
70.7
|
1.0
|
CA
|
D:GLN981
|
4.4
|
73.7
|
1.0
|
CB
|
D:ASP980
|
4.6
|
70.7
|
1.0
|
N
|
D:PHE978
|
4.6
|
61.2
|
1.0
|
C
|
D:ASP983
|
4.7
|
78.1
|
1.0
|
CB
|
D:ASP983
|
4.7
|
78.1
|
1.0
|
C
|
D:GLN981
|
4.7
|
73.7
|
1.0
|
CB
|
D:GLN977
|
4.7
|
64.3
|
1.0
|
O
|
D:HOH1324
|
4.8
|
66.3
|
1.0
|
O
|
D:GLN981
|
4.8
|
73.7
|
1.0
|
CA
|
D:PHE978
|
4.8
|
61.2
|
1.0
|
N
|
D:ASP983
|
4.9
|
78.1
|
1.0
|
CA
|
D:ASP983
|
5.0
|
78.1
|
1.0
|
|
Calcium binding site 8 out
of 8 in 7pxe
Go back to
Calcium Binding Sites List in 7pxe
Calcium binding site 8 out
of 8 in the CA2+ Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca1202
b:62.0
occ:1.00
|
O
|
D:ARG528
|
2.4
|
68.8
|
1.0
|
O
|
D:GLN616
|
2.4
|
67.7
|
1.0
|
OE1
|
D:GLU550
|
2.5
|
65.9
|
1.0
|
O
|
D:GLY548
|
2.5
|
64.8
|
1.0
|
OD2
|
D:ASP381
|
2.8
|
74.2
|
1.0
|
OE2
|
D:GLU550
|
2.9
|
65.9
|
1.0
|
CD
|
D:GLU550
|
3.0
|
65.9
|
1.0
|
CG
|
D:ASP381
|
3.4
|
74.2
|
1.0
|
C
|
D:ARG528
|
3.5
|
68.8
|
1.0
|
C
|
D:GLY548
|
3.6
|
64.8
|
1.0
|
C
|
D:GLN616
|
3.6
|
67.7
|
1.0
|
CB
|
D:ASP381
|
4.1
|
74.2
|
1.0
|
CA
|
D:GLY548
|
4.1
|
64.8
|
1.0
|
OD1
|
D:ASP381
|
4.1
|
74.2
|
1.0
|
CA
|
D:SER529
|
4.3
|
77.3
|
1.0
|
OH
|
D:TYR552
|
4.3
|
67.4
|
1.0
|
N
|
D:SER529
|
4.3
|
77.3
|
1.0
|
N
|
D:ARG528
|
4.3
|
68.8
|
1.0
|
NE2
|
D:GLN616
|
4.3
|
67.7
|
1.0
|
CA
|
D:GLN616
|
4.4
|
67.7
|
1.0
|
CG
|
D:GLU550
|
4.5
|
65.9
|
1.0
|
CA
|
D:ARG528
|
4.5
|
68.8
|
1.0
|
N
|
D:SER617
|
4.6
|
71.7
|
1.0
|
N
|
D:MET549
|
4.7
|
66.3
|
1.0
|
CA
|
D:SER617
|
4.7
|
71.7
|
1.0
|
CB
|
D:SER617
|
5.0
|
71.7
|
1.0
|
CA
|
D:MET549
|
5.0
|
66.3
|
1.0
|
|
Reference:
T.Raisch,
A.Brockmann,
U.Ebbinghaus-Kintscher,
J.Freigang,
O.Gutbrod,
J.Kubicek,
B.Maertens,
O.Hofnagel,
S.Raunser.
Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W
Page generated: Fri Jul 19 03:19:26 2024
|