Calcium in PDB 7s8c: Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole

The structure of Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole also contains other interesting chemical elements:

Chlorine

(Cl)

13 atoms

The binding sites of Calcium atom in the Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole (pdb code 7s8c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole, PDB code: 7s8c:

Calcium binding site 1 out of 1 in the Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of Human TRPV6 in Complex with Inhibitor Econazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca709 b:34.5 occ:1.00 OD2 B:ASP542 2.5 5.5 1.0 OD2 D:ASP542 2.5 4.8 1.0 OD2 A:ASP542 2.5 5.0 1.0 OD2 C:ASP542 2.5 4.7 1.0 OD1 D:ASP542 2.5 4.8 1.0 OD1 B:ASP542 2.5 5.5 1.0 OD1 C:ASP542 2.6 4.7 1.0 OD1 A:ASP542 2.6 5.0 1.0 CG D:ASP542 2.8 4.8 1.0 CG B:ASP542 2.8 5.5 1.0 CG C:ASP542 2.8 4.7 1.0 CG A:ASP542 2.8 5.0 1.0 CB B:ASP542 4.2 5.5 1.0 CB D:ASP542 4.2 4.8 1.0 CB C:ASP542 4.2 4.7 1.0 CB A:ASP542 4.2 5.0 1.0 N B:ASP542 4.9 5.5 1.0 N D:ASP542 4.9 4.8 1.0 N C:ASP542 4.9 4.7 1.0 CA B:ASP542 4.9 5.5 1.0 CA D:ASP542 4.9 4.8 1.0 N A:ASP542 4.9 5.0 1.0 CA C:ASP542 4.9 4.7 1.0 CA A:ASP542 5.0 5.0 1.0

A.Neuberger, K.D.Nadezhdin, A.I.Sobolevsky. Structural Mechanisms of TRPV6 Inhibition By Ruthenium Red and Econazole. Nat Commun V. 12 6284 2021.
ISSN: ESSN 2041-1723
PubMed: 34725357
DOI: 10.1038/S41467-021-26608-X