Calcium in PDB 7zrp: 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
Enzymatic activity of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
All present enzymatic activity of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex:
2.7.11.17;
Protein crystallography data
The structure of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex, PDB code: 7zrp
was solved by
N.Helassa,
S.Antonyuk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
53.24 /
2.65
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
64.283,
72.59,
78.156,
90,
90,
90
|
|
R / Rfree (%)
|
20.7 /
27.2
|
Other elements in 7zrp:
The structure of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
(pdb code 7zrp). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex, PDB code: 7zrp:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 1 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca201
b:70.3
occ:1.00
|
OD1
|
A:ASP22
|
2.4
|
82.2
|
1.0
|
|
O
|
A:THR26
|
2.4
|
61.2
|
1.0
|
|
OD1
|
A:ASP20
|
2.4
|
76.2
|
1.0
|
|
OE2
|
A:GLU31
|
2.4
|
67.3
|
1.0
|
|
OE1
|
A:GLU31
|
2.4
|
62.7
|
1.0
|
|
OD1
|
A:ASP24
|
2.5
|
71.9
|
1.0
|
|
CD
|
A:GLU31
|
2.8
|
68.0
|
1.0
|
|
O
|
A:HOH305
|
2.9
|
64.1
|
1.0
|
|
CG
|
A:ASP24
|
3.1
|
75.3
|
1.0
|
|
CG
|
A:ASP22
|
3.1
|
89.7
|
1.0
|
|
H
|
A:ASP24
|
3.3
|
72.5
|
1.0
|
|
OD2
|
A:ASP22
|
3.3
|
89.2
|
1.0
|
|
OD2
|
A:ASP24
|
3.5
|
83.3
|
1.0
|
|
HG1
|
A:THR26
|
3.5
|
65.0
|
0.0
|
|
H
|
A:THR26
|
3.6
|
74.9
|
1.0
|
|
C
|
A:THR26
|
3.6
|
73.2
|
1.0
|
|
H
|
A:ASP22
|
3.6
|
89.8
|
1.0
|
|
CG
|
A:ASP20
|
3.6
|
77.3
|
1.0
|
|
HA
|
A:ASP20
|
3.7
|
71.9
|
1.0
|
|
HG22
|
A:THR28
|
3.8
|
66.7
|
1.0
|
|
OG1
|
A:THR26
|
3.8
|
65.5
|
1.0
|
|
HA
|
A:ILE27
|
4.0
|
61.9
|
1.0
|
|
N
|
A:ASP24
|
4.1
|
71.9
|
1.0
|
|
CB
|
A:ASP24
|
4.2
|
70.4
|
1.0
|
|
H
|
A:GLY23
|
4.2
|
80.4
|
1.0
|
|
H
|
A:THR28
|
4.2
|
55.5
|
1.0
|
|
HB3
|
A:ASP24
|
4.3
|
71.2
|
1.0
|
|
N
|
A:THR26
|
4.3
|
76.7
|
1.0
|
|
H
|
A:LYS21
|
4.3
|
80.4
|
1.0
|
|
CG
|
A:GLU31
|
4.3
|
66.8
|
1.0
|
|
N
|
A:ASP22
|
4.3
|
94.3
|
1.0
|
|
CA
|
A:ASP20
|
4.3
|
74.0
|
1.0
|
|
CA
|
A:THR26
|
4.4
|
73.1
|
1.0
|
|
CB
|
A:ASP22
|
4.4
|
82.6
|
1.0
|
|
CB
|
A:ASP20
|
4.5
|
78.3
|
1.0
|
|
C
|
A:ASP20
|
4.5
|
72.4
|
1.0
|
|
OD2
|
A:ASP20
|
4.5
|
82.4
|
1.0
|
|
N
|
A:ILE27
|
4.6
|
66.2
|
1.0
|
|
N
|
A:GLY23
|
4.6
|
82.1
|
1.0
|
|
CA
|
A:ASP24
|
4.6
|
68.9
|
1.0
|
|
N
|
A:LYS21
|
4.6
|
81.8
|
1.0
|
|
HB2
|
A:ASP20
|
4.7
|
77.0
|
1.0
|
|
HG1
|
A:THR28
|
4.7
|
58.9
|
0.0
|
|
HG3
|
A:GLU31
|
4.7
|
66.5
|
1.0
|
|
HG2
|
A:GLU31
|
4.7
|
66.6
|
1.0
|
|
CA
|
A:ILE27
|
4.7
|
63.0
|
1.0
|
|
CA
|
A:ASP22
|
4.7
|
86.2
|
1.0
|
|
CB
|
A:THR26
|
4.8
|
71.6
|
1.0
|
|
HB3
|
A:ASP22
|
4.8
|
85.1
|
1.0
|
|
CG2
|
A:THR28
|
4.8
|
68.6
|
1.0
|
|
C
|
A:ASP22
|
4.8
|
79.8
|
1.0
|
|
C
|
A:ASP24
|
4.8
|
76.3
|
1.0
|
|
H
|
A:GLY25
|
4.9
|
69.3
|
1.0
|
|
N
|
A:THR28
|
4.9
|
53.5
|
1.0
|
|
N
|
A:GLY25
|
5.0
|
68.0
|
1.0
|
|
HB2
|
A:ASP24
|
5.0
|
71.2
|
1.0
|
|
Calcium binding site 2 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 2 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca202
b:81.3
occ:1.00
|
OE1
|
A:GLU67
|
2.4
|
82.4
|
1.0
|
|
OD1
|
A:ASN60
|
2.4
|
67.3
|
1.0
|
|
OD1
|
A:ASP56
|
2.4
|
78.9
|
1.0
|
|
O
|
A:THR62
|
2.4
|
78.9
|
1.0
|
|
OD2
|
A:ASP58
|
2.4
|
90.9
|
1.0
|
|
OE2
|
A:GLU67
|
2.9
|
92.7
|
1.0
|
|
CD
|
A:GLU67
|
3.0
|
89.1
|
1.0
|
|
CG
|
A:ASP58
|
3.3
|
81.8
|
1.0
|
|
H
|
A:ASN60
|
3.3
|
78.7
|
1.0
|
|
CG
|
A:ASN60
|
3.5
|
76.0
|
1.0
|
|
H
|
A:GLY59
|
3.5
|
93.4
|
1.0
|
|
CG
|
A:ASP56
|
3.6
|
75.0
|
1.0
|
|
HA
|
A:ILE63
|
3.6
|
73.5
|
1.0
|
|
OD1
|
A:ASP58
|
3.6
|
78.0
|
1.0
|
|
C
|
A:THR62
|
3.6
|
66.6
|
1.0
|
|
H
|
A:THR62
|
3.8
|
75.2
|
1.0
|
|
HA
|
A:ASP56
|
4.0
|
86.8
|
1.0
|
|
HD22
|
A:ASN60
|
4.0
|
75.3
|
0.0
|
|
H
|
A:ASP64
|
4.1
|
80.6
|
1.0
|
|
N
|
A:ASN60
|
4.2
|
77.3
|
1.0
|
|
ND2
|
A:ASN60
|
4.2
|
76.8
|
1.0
|
|
OD2
|
A:ASP56
|
4.2
|
63.4
|
1.0
|
|
H
|
A:ASP58
|
4.2
|
91.3
|
1.0
|
|
HG1
|
A:THR62
|
4.3
|
65.0
|
0.0
|
|
H
|
A:GLY61
|
4.4
|
78.2
|
1.0
|
|
N
|
A:THR62
|
4.4
|
74.9
|
1.0
|
|
N
|
A:GLY59
|
4.4
|
97.8
|
1.0
|
|
CA
|
A:ILE63
|
4.4
|
75.6
|
1.0
|
|
CG
|
A:GLU67
|
4.4
|
96.8
|
1.0
|
|
N
|
A:ILE63
|
4.5
|
63.2
|
1.0
|
|
CB
|
A:ASP58
|
4.5
|
82.2
|
1.0
|
|
CB
|
A:ASN60
|
4.6
|
75.3
|
1.0
|
|
OG1
|
A:THR62
|
4.6
|
66.7
|
1.0
|
|
HB3
|
A:ASP58
|
4.6
|
82.9
|
1.0
|
|
CA
|
A:THR62
|
4.6
|
70.1
|
1.0
|
|
CB
|
A:ASP56
|
4.6
|
80.0
|
1.0
|
|
CA
|
A:ASP56
|
4.7
|
87.0
|
1.0
|
|
HG3
|
A:GLU67
|
4.7
|
93.4
|
1.0
|
|
HB3
|
A:ASN60
|
4.7
|
75.7
|
1.0
|
|
CA
|
A:ASN60
|
4.8
|
76.6
|
1.0
|
|
N
|
A:GLY61
|
4.8
|
77.4
|
1.0
|
|
N
|
A:ASP64
|
4.8
|
79.8
|
1.0
|
|
HB2
|
A:ASP56
|
4.9
|
80.3
|
1.0
|
|
C
|
A:ASN60
|
4.9
|
79.9
|
1.0
|
|
N
|
A:ASP58
|
4.9
|
89.7
|
1.0
|
|
HG13
|
A:ILE63
|
4.9
|
81.6
|
1.0
|
|
HG2
|
A:GLU67
|
4.9
|
93.4
|
1.0
|
|
OD2
|
A:ASP64
|
5.0
|
86.3
|
1.0
|
|
HG12
|
A:ILE63
|
5.0
|
81.6
|
1.0
|
|
Calcium binding site 3 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 3 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca203
b:50.3
occ:1.00
|
O
|
A:TYR99
|
2.4
|
52.8
|
1.0
|
|
OD1
|
A:ASP93
|
2.4
|
44.3
|
1.0
|
|
OE1
|
A:GLU104
|
2.4
|
53.9
|
1.0
|
|
OD1
|
A:ASN97
|
2.4
|
52.0
|
1.0
|
|
OE2
|
A:GLU104
|
2.4
|
52.4
|
1.0
|
|
OD1
|
A:ASP95
|
2.4
|
67.0
|
1.0
|
|
CD
|
A:GLU104
|
2.8
|
51.9
|
1.0
|
|
CG
|
A:ASP95
|
3.1
|
65.6
|
1.0
|
|
OD2
|
A:ASP95
|
3.2
|
72.5
|
1.0
|
|
H
|
A:ASP95
|
3.4
|
59.0
|
1.0
|
|
CG
|
A:ASN97
|
3.5
|
56.8
|
1.0
|
|
H
|
A:ASN97
|
3.6
|
53.2
|
1.0
|
|
C
|
A:TYR99
|
3.6
|
53.1
|
1.0
|
|
H
|
A:TYR99
|
3.6
|
53.0
|
1.0
|
|
CG
|
A:ASP93
|
3.6
|
44.9
|
1.0
|
|
HA
|
A:ASP93
|
3.7
|
45.9
|
1.0
|
|
HA
|
A:ILE100
|
3.8
|
49.8
|
1.0
|
|
H
|
A:SER101
|
3.9
|
51.4
|
1.0
|
|
HD22
|
A:ASN97
|
4.1
|
62.1
|
0.0
|
|
H
|
A:LYS94
|
4.1
|
58.7
|
1.0
|
|
N
|
A:ASP95
|
4.2
|
58.6
|
1.0
|
|
ND2
|
A:ASN97
|
4.2
|
59.8
|
1.0
|
|
CG
|
A:GLU104
|
4.3
|
47.8
|
1.0
|
|
N
|
A:TYR99
|
4.3
|
51.1
|
1.0
|
|
CA
|
A:ASP93
|
4.3
|
45.6
|
1.0
|
|
HB2
|
A:TYR99
|
4.4
|
54.7
|
1.0
|
|
CB
|
A:ASP95
|
4.4
|
63.1
|
1.0
|
|
H
|
A:GLY98
|
4.4
|
57.1
|
1.0
|
|
N
|
A:LYS94
|
4.4
|
60.5
|
1.0
|
|
C
|
A:ASP93
|
4.4
|
51.9
|
1.0
|
|
N
|
A:ASN97
|
4.4
|
53.4
|
1.0
|
|
HB3
|
A:ASN97
|
4.4
|
54.1
|
1.0
|
|
H
|
A:GLY96
|
4.5
|
51.5
|
1.0
|
|
OD2
|
A:ASP93
|
4.5
|
43.3
|
1.0
|
|
CB
|
A:ASN97
|
4.5
|
52.6
|
1.0
|
|
CB
|
A:ASP93
|
4.5
|
43.1
|
1.0
|
|
N
|
A:ILE100
|
4.5
|
46.9
|
1.0
|
|
CA
|
A:TYR99
|
4.5
|
52.1
|
1.0
|
|
CA
|
A:ILE100
|
4.5
|
49.6
|
1.0
|
|
HG3
|
A:GLU104
|
4.5
|
48.6
|
1.0
|
|
N
|
A:SER101
|
4.6
|
51.7
|
1.0
|
|
HG2
|
A:GLU104
|
4.7
|
48.6
|
1.0
|
|
CA
|
A:ASP95
|
4.7
|
58.3
|
1.0
|
|
N
|
A:GLY96
|
4.8
|
50.2
|
1.0
|
|
HB2
|
A:ASP93
|
4.8
|
44.1
|
1.0
|
|
HB3
|
A:SER101
|
4.8
|
54.0
|
1.0
|
|
HB3
|
A:ASP95
|
4.9
|
62.5
|
1.0
|
|
N
|
A:GLY98
|
4.9
|
57.4
|
1.0
|
|
C
|
A:ASP95
|
4.9
|
55.6
|
1.0
|
|
CA
|
A:ASN97
|
4.9
|
54.7
|
1.0
|
|
O
|
A:ASP93
|
5.0
|
57.0
|
1.0
|
|
CB
|
A:TYR99
|
5.0
|
55.2
|
1.0
|
|
Calcium binding site 4 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 4 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca204
b:47.0
occ:1.00
|
O
|
A:GLN135
|
2.4
|
57.9
|
1.0
|
|
OD1
|
A:ASP129
|
2.4
|
46.2
|
1.0
|
|
OE2
|
A:GLU140
|
2.4
|
51.6
|
1.0
|
|
OD1
|
A:ASP133
|
2.4
|
56.8
|
1.0
|
|
OD1
|
A:ASP131
|
2.4
|
59.4
|
1.0
|
|
O
|
A:HOH304
|
2.5
|
41.9
|
1.0
|
|
OE1
|
A:GLU140
|
2.5
|
49.2
|
1.0
|
|
CD
|
A:GLU140
|
2.8
|
44.0
|
1.0
|
|
HA
|
A:ASP129
|
3.2
|
53.0
|
1.0
|
|
CG
|
A:ASP133
|
3.2
|
62.5
|
1.0
|
|
CG
|
A:ASP131
|
3.2
|
60.3
|
1.0
|
|
H
|
A:ASP131
|
3.3
|
60.0
|
1.0
|
|
H
|
A:GLN135
|
3.4
|
61.3
|
1.0
|
|
CG
|
A:ASP129
|
3.4
|
46.7
|
1.0
|
|
H
|
A:ASP133
|
3.4
|
61.1
|
1.0
|
|
C
|
A:GLN135
|
3.5
|
62.7
|
1.0
|
|
HA
|
A:VAL136
|
3.5
|
52.7
|
1.0
|
|
OD2
|
A:ASP133
|
3.6
|
53.5
|
1.0
|
|
OD2
|
A:ASP131
|
3.6
|
62.6
|
1.0
|
|
H
|
A:ASN137
|
3.8
|
45.3
|
1.0
|
|
CA
|
A:ASP129
|
3.9
|
52.8
|
1.0
|
|
H
|
A:ILE130
|
4.0
|
63.7
|
1.0
|
|
H
|
A:GLY132
|
4.0
|
60.8
|
1.0
|
|
CB
|
A:ASP129
|
4.1
|
48.4
|
1.0
|
|
HB2
|
A:ASP129
|
4.1
|
49.0
|
1.0
|
|
H
|
A:GLY134
|
4.1
|
53.8
|
1.0
|
|
N
|
A:ASP131
|
4.2
|
58.7
|
1.0
|
|
N
|
A:GLN135
|
4.2
|
61.6
|
1.0
|
|
N
|
A:ASP133
|
4.2
|
61.7
|
1.0
|
|
CA
|
A:VAL136
|
4.3
|
53.4
|
1.0
|
|
N
|
A:VAL136
|
4.3
|
56.6
|
1.0
|
|
N
|
A:ILE130
|
4.3
|
64.7
|
1.0
|
|
C
|
A:ASP129
|
4.3
|
59.2
|
1.0
|
|
CG
|
A:GLU140
|
4.3
|
42.3
|
1.0
|
|
OD2
|
A:ASP129
|
4.4
|
49.4
|
1.0
|
|
CB
|
A:ASP133
|
4.4
|
57.2
|
1.0
|
|
CB
|
A:ASP131
|
4.4
|
54.2
|
1.0
|
|
N
|
A:ASN137
|
4.4
|
42.8
|
1.0
|
|
N
|
A:GLY132
|
4.4
|
61.6
|
1.0
|
|
CA
|
A:GLN135
|
4.4
|
63.9
|
1.0
|
|
CA
|
A:ASP131
|
4.6
|
58.4
|
1.0
|
|
HB3
|
A:ASN137
|
4.6
|
48.0
|
1.0
|
|
HB3
|
A:ASP133
|
4.7
|
58.9
|
1.0
|
|
HG3
|
A:GLU140
|
4.7
|
43.4
|
1.0
|
|
N
|
A:GLY134
|
4.7
|
54.3
|
1.0
|
|
C
|
A:ASP131
|
4.7
|
60.5
|
1.0
|
|
CA
|
A:ASP133
|
4.8
|
59.5
|
1.0
|
|
HB3
|
A:ASP131
|
4.8
|
56.6
|
1.0
|
|
HG2
|
A:GLU140
|
4.8
|
43.4
|
1.0
|
|
C
|
A:VAL136
|
4.8
|
50.9
|
1.0
|
|
HD2
|
A:TYR99
|
4.9
|
55.3
|
1.0
|
|
HG3
|
A:GLN135
|
4.9
|
63.2
|
1.0
|
|
HB2
|
A:GLU140
|
4.9
|
44.2
|
1.0
|
|
HB3
|
A:ASP129
|
5.0
|
49.0
|
1.0
|
|
Calcium binding site 5 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 5 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca201
b:58.0
occ:1.00
|
O
|
C:THR26
|
2.4
|
60.0
|
1.0
|
|
O
|
C:HOH303
|
2.4
|
53.4
|
1.0
|
|
OE2
|
C:GLU31
|
2.4
|
63.6
|
1.0
|
|
OE1
|
C:GLU31
|
2.4
|
74.5
|
1.0
|
|
OD1
|
C:ASP24
|
2.4
|
61.9
|
1.0
|
|
OD1
|
C:ASP20
|
2.4
|
49.6
|
1.0
|
|
OD1
|
C:ASP22
|
2.4
|
59.4
|
1.0
|
|
CD
|
C:GLU31
|
2.7
|
70.1
|
1.0
|
|
CG
|
C:ASP24
|
3.1
|
55.8
|
1.0
|
|
CG
|
C:ASP22
|
3.2
|
68.0
|
1.0
|
|
H
|
C:ASP24
|
3.3
|
64.6
|
1.0
|
|
OD2
|
C:ASP24
|
3.4
|
55.4
|
1.0
|
|
OD2
|
C:ASP22
|
3.4
|
75.7
|
1.0
|
|
HG1
|
C:THR26
|
3.4
|
64.2
|
0.0
|
|
H
|
C:THR26
|
3.5
|
72.1
|
1.0
|
|
C
|
C:THR26
|
3.6
|
75.3
|
1.0
|
|
H
|
C:ASP22
|
3.6
|
71.7
|
1.0
|
|
CG
|
C:ASP20
|
3.7
|
65.0
|
1.0
|
|
HA
|
C:ASP20
|
3.8
|
61.4
|
1.0
|
|
OG1
|
C:THR26
|
3.8
|
65.4
|
1.0
|
|
HG22
|
C:THR28
|
3.8
|
69.8
|
1.0
|
|
HA
|
C:ILE27
|
4.0
|
66.2
|
1.0
|
|
CB
|
C:ASP24
|
4.1
|
57.8
|
1.0
|
|
N
|
C:ASP24
|
4.2
|
66.1
|
1.0
|
|
H
|
C:THR28
|
4.2
|
66.2
|
1.0
|
|
HB3
|
C:ASP24
|
4.2
|
58.0
|
1.0
|
|
N
|
C:THR26
|
4.3
|
69.4
|
1.0
|
|
CG
|
C:GLU31
|
4.3
|
71.2
|
1.0
|
|
H
|
C:LYS21
|
4.3
|
67.2
|
1.0
|
|
CA
|
C:THR26
|
4.4
|
73.1
|
1.0
|
|
CA
|
C:ASP20
|
4.4
|
61.4
|
1.0
|
|
H
|
C:GLY23
|
4.4
|
65.0
|
1.0
|
|
N
|
C:ASP22
|
4.4
|
71.4
|
1.0
|
|
CB
|
C:ASP22
|
4.5
|
70.6
|
1.0
|
|
CB
|
C:ASP20
|
4.5
|
64.3
|
1.0
|
|
C
|
C:ASP20
|
4.5
|
62.5
|
1.0
|
|
N
|
C:ILE27
|
4.6
|
69.7
|
1.0
|
|
CA
|
C:ASP24
|
4.6
|
60.7
|
1.0
|
|
OD2
|
C:ASP20
|
4.6
|
71.2
|
1.0
|
|
N
|
C:LYS21
|
4.6
|
67.6
|
1.0
|
|
HG3
|
C:GLU31
|
4.6
|
70.9
|
1.0
|
|
HB2
|
C:ASP20
|
4.7
|
63.8
|
1.0
|
|
HG2
|
C:GLU31
|
4.7
|
70.9
|
1.0
|
|
N
|
C:GLY23
|
4.7
|
63.9
|
1.0
|
|
HG1
|
C:THR28
|
4.7
|
66.5
|
0.0
|
|
CA
|
C:ILE27
|
4.7
|
65.7
|
1.0
|
|
CB
|
C:THR26
|
4.7
|
72.2
|
1.0
|
|
CG2
|
C:THR28
|
4.8
|
68.3
|
1.0
|
|
CA
|
C:ASP22
|
4.8
|
69.9
|
1.0
|
|
C
|
C:ASP24
|
4.8
|
64.7
|
1.0
|
|
HB3
|
C:ASP22
|
4.8
|
69.8
|
1.0
|
|
H
|
C:GLY25
|
4.9
|
66.5
|
1.0
|
|
C
|
C:ASP22
|
4.9
|
67.0
|
1.0
|
|
N
|
C:THR28
|
4.9
|
67.2
|
1.0
|
|
HB2
|
C:ASP24
|
5.0
|
58.0
|
1.0
|
|
HB2
|
C:GLU31
|
5.0
|
70.1
|
1.0
|
|
Calcium binding site 6 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 6 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca202
b:85.3
occ:1.00
|
OD2
|
C:ASP58
|
2.4
|
103.5
|
1.0
|
|
O
|
C:THR62
|
2.4
|
73.1
|
1.0
|
|
OD1
|
C:ASN60
|
2.4
|
93.5
|
1.0
|
|
OE1
|
C:GLU67
|
2.4
|
72.3
|
1.0
|
|
OD1
|
C:ASP56
|
2.4
|
95.3
|
1.0
|
|
OE2
|
C:GLU67
|
3.1
|
69.2
|
1.0
|
|
CD
|
C:GLU67
|
3.1
|
69.1
|
1.0
|
|
CG
|
C:ASP58
|
3.1
|
104.5
|
1.0
|
|
OD1
|
C:ASP58
|
3.3
|
86.8
|
1.0
|
|
H
|
C:ASN60
|
3.4
|
106.7
|
1.0
|
|
CG
|
C:ASN60
|
3.6
|
97.5
|
1.0
|
|
CG
|
C:ASP56
|
3.6
|
89.4
|
1.0
|
|
C
|
C:THR62
|
3.6
|
82.1
|
1.0
|
|
H
|
C:GLY59
|
3.6
|
103.0
|
1.0
|
|
HA
|
C:ILE63
|
3.7
|
84.7
|
1.0
|
|
H
|
C:THR62
|
3.7
|
97.8
|
1.0
|
|
HD22
|
C:ASN60
|
4.1
|
83.6
|
0.0
|
|
H
|
C:ASP64
|
4.1
|
82.6
|
1.0
|
|
HG1
|
C:THR62
|
4.2
|
90.7
|
0.0
|
|
HA
|
C:ASP56
|
4.2
|
88.9
|
1.0
|
|
OD2
|
C:ASP56
|
4.2
|
72.7
|
1.0
|
|
N
|
C:ASN60
|
4.3
|
108.5
|
1.0
|
|
ND2
|
C:ASN60
|
4.3
|
80.3
|
1.0
|
|
H
|
C:GLY61
|
4.4
|
113.1
|
1.0
|
|
N
|
C:THR62
|
4.4
|
100.2
|
1.0
|
|
OG1
|
C:THR62
|
4.4
|
88.3
|
1.0
|
|
N
|
C:ILE63
|
4.5
|
82.9
|
1.0
|
|
CB
|
C:ASP58
|
4.5
|
101.1
|
1.0
|
|
CA
|
C:ILE63
|
4.5
|
85.8
|
1.0
|
|
N
|
C:GLY59
|
4.5
|
102.2
|
1.0
|
|
CA
|
C:THR62
|
4.6
|
87.1
|
1.0
|
|
CG
|
C:GLU67
|
4.6
|
67.2
|
1.0
|
|
HB3
|
C:ASP58
|
4.6
|
102.2
|
1.0
|
|
CB
|
C:ASN60
|
4.6
|
106.4
|
1.0
|
|
CB
|
C:ASP56
|
4.7
|
87.5
|
1.0
|
|
HB3
|
C:ASN60
|
4.8
|
104.6
|
1.0
|
|
HG3
|
C:GLU67
|
4.8
|
68.6
|
1.0
|
|
N
|
C:GLY61
|
4.8
|
115.3
|
1.0
|
|
CA
|
C:ASP56
|
4.8
|
88.6
|
1.0
|
|
N
|
C:ASP64
|
4.8
|
83.7
|
1.0
|
|
CA
|
C:ASN60
|
4.8
|
108.1
|
1.0
|
|
OD2
|
C:ASP64
|
4.9
|
95.8
|
1.0
|
|
HB2
|
C:ASP56
|
4.9
|
88.2
|
1.0
|
|
HG13
|
C:ILE63
|
4.9
|
84.5
|
1.0
|
|
C
|
C:ASN60
|
5.0
|
110.9
|
1.0
|
|
Calcium binding site 7 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 7 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca203
b:58.3
occ:1.00
|
OD1
|
C:ASN97
|
2.4
|
72.5
|
1.0
|
|
O
|
C:TYR99
|
2.4
|
51.9
|
1.0
|
|
OD1
|
C:ASP95
|
2.4
|
74.0
|
1.0
|
|
OE1
|
C:GLU104
|
2.4
|
57.3
|
1.0
|
|
OE2
|
C:GLU104
|
2.4
|
51.1
|
1.0
|
|
OD1
|
C:ASP93
|
2.4
|
56.1
|
1.0
|
|
CD
|
C:GLU104
|
2.7
|
52.7
|
1.0
|
|
CG
|
C:ASP95
|
3.1
|
77.3
|
1.0
|
|
OD2
|
C:ASP95
|
3.3
|
87.8
|
1.0
|
|
H
|
C:ASP95
|
3.4
|
68.3
|
1.0
|
|
CG
|
C:ASN97
|
3.4
|
73.4
|
1.0
|
|
H
|
C:ASN97
|
3.6
|
65.5
|
1.0
|
|
C
|
C:TYR99
|
3.6
|
64.6
|
1.0
|
|
H
|
C:TYR99
|
3.6
|
73.1
|
1.0
|
|
CG
|
C:ASP93
|
3.7
|
55.5
|
1.0
|
|
HA
|
C:ASP93
|
3.7
|
57.3
|
1.0
|
|
HA
|
C:ILE100
|
3.8
|
61.6
|
1.0
|
|
H
|
C:SER101
|
3.8
|
58.2
|
1.0
|
|
HD22
|
C:ASN97
|
4.0
|
82.0
|
0.0
|
|
H
|
C:LYS94
|
4.1
|
64.4
|
1.0
|
|
ND2
|
C:ASN97
|
4.1
|
81.4
|
1.0
|
|
CG
|
C:GLU104
|
4.2
|
52.1
|
1.0
|
|
N
|
C:ASP95
|
4.2
|
67.8
|
1.0
|
|
N
|
C:TYR99
|
4.3
|
72.6
|
1.0
|
|
CA
|
C:ASP93
|
4.4
|
59.1
|
1.0
|
|
H
|
C:GLY98
|
4.4
|
73.9
|
1.0
|
|
H
|
C:GLY96
|
4.4
|
65.9
|
1.0
|
|
HB3
|
C:ASN97
|
4.4
|
68.6
|
1.0
|
|
N
|
C:LYS94
|
4.4
|
65.2
|
1.0
|
|
N
|
C:ASN97
|
4.4
|
65.2
|
1.0
|
|
HB2
|
C:TYR99
|
4.4
|
73.8
|
1.0
|
|
CB
|
C:ASP95
|
4.4
|
67.0
|
1.0
|
|
C
|
C:ASP93
|
4.4
|
60.5
|
1.0
|
|
CB
|
C:ASN97
|
4.5
|
66.5
|
1.0
|
|
HG3
|
C:GLU104
|
4.5
|
52.2
|
1.0
|
|
OD2
|
C:ASP93
|
4.5
|
59.1
|
1.0
|
|
CA
|
C:TYR99
|
4.5
|
72.0
|
1.0
|
|
N
|
C:ILE100
|
4.5
|
66.8
|
1.0
|
|
CA
|
C:ILE100
|
4.5
|
61.0
|
1.0
|
|
CB
|
C:ASP93
|
4.6
|
55.6
|
1.0
|
|
N
|
C:SER101
|
4.6
|
59.5
|
1.0
|
|
HG2
|
C:GLU104
|
4.6
|
52.2
|
1.0
|
|
CA
|
C:ASP95
|
4.7
|
69.6
|
1.0
|
|
N
|
C:GLY96
|
4.8
|
65.3
|
1.0
|
|
HB3
|
C:SER101
|
4.8
|
53.0
|
1.0
|
|
N
|
C:GLY98
|
4.8
|
73.9
|
1.0
|
|
HB2
|
C:ASP93
|
4.9
|
56.4
|
1.0
|
|
CA
|
C:ASN97
|
4.9
|
68.7
|
1.0
|
|
HB3
|
C:ASP95
|
4.9
|
69.9
|
1.0
|
|
OG
|
C:SER101
|
4.9
|
54.2
|
1.0
|
|
C
|
C:ASP95
|
4.9
|
69.0
|
1.0
|
|
HD21
|
C:ASN97
|
4.9
|
82.0
|
0.0
|
|
O
|
C:ASP93
|
5.0
|
65.1
|
1.0
|
|
Calcium binding site 8 out
of 8 in 7zrp
Go back to
Calcium Binding Sites List in 7zrp
Calcium binding site 8 out
of 8 in the 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of 2.65 Angstrom Crystal Structure of Ca/Cam:Camkiidelta Peptide Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca204
b:72.5
occ:1.00
|
O
|
C:GLN135
|
2.4
|
71.7
|
1.0
|
|
OD1
|
C:ASP129
|
2.4
|
62.9
|
1.0
|
|
OD1
|
C:ASP131
|
2.4
|
79.8
|
1.0
|
|
OD1
|
C:ASP133
|
2.4
|
71.3
|
1.0
|
|
OE1
|
C:GLU140
|
2.4
|
66.0
|
1.0
|
|
OE2
|
C:GLU140
|
2.4
|
69.4
|
1.0
|
|
CD
|
C:GLU140
|
2.7
|
67.0
|
1.0
|
|
CG
|
C:ASP131
|
3.2
|
81.4
|
1.0
|
|
CG
|
C:ASP133
|
3.2
|
72.5
|
1.0
|
|
HA
|
C:ASP129
|
3.2
|
75.7
|
1.0
|
|
H
|
C:ASP131
|
3.3
|
78.3
|
1.0
|
|
H
|
C:GLN135
|
3.4
|
87.0
|
1.0
|
|
H
|
C:ASP133
|
3.4
|
74.7
|
1.0
|
|
CG
|
C:ASP129
|
3.4
|
77.5
|
1.0
|
|
OD2
|
C:ASP133
|
3.5
|
82.3
|
1.0
|
|
C
|
C:GLN135
|
3.5
|
76.1
|
1.0
|
|
OD2
|
C:ASP131
|
3.5
|
78.6
|
1.0
|
|
HA
|
C:VAL136
|
3.6
|
61.1
|
1.0
|
|
H
|
C:ASN137
|
3.9
|
65.4
|
1.0
|
|
H
|
C:GLY132
|
3.9
|
78.7
|
1.0
|
|
H
|
C:ILE130
|
3.9
|
78.7
|
1.0
|
|
CA
|
C:ASP129
|
4.0
|
76.7
|
1.0
|
|
N
|
C:ASP131
|
4.1
|
79.1
|
1.0
|
|
CB
|
C:ASP129
|
4.1
|
77.6
|
1.0
|
|
H
|
C:GLY134
|
4.1
|
73.3
|
1.0
|
|
N
|
C:GLN135
|
4.2
|
90.9
|
1.0
|
|
HB2
|
C:ASP129
|
4.2
|
77.4
|
1.0
|
|
N
|
C:ASP133
|
4.2
|
75.9
|
1.0
|
|
CG
|
C:GLU140
|
4.3
|
67.0
|
1.0
|
|
N
|
C:ILE130
|
4.3
|
78.9
|
1.0
|
|
C
|
C:ASP129
|
4.3
|
77.5
|
1.0
|
|
CB
|
C:ASP131
|
4.4
|
80.2
|
1.0
|
|
CA
|
C:VAL136
|
4.4
|
60.1
|
1.0
|
|
N
|
C:VAL136
|
4.4
|
67.4
|
1.0
|
|
OD2
|
C:ASP129
|
4.4
|
82.0
|
1.0
|
|
N
|
C:GLY132
|
4.4
|
78.6
|
1.0
|
|
CB
|
C:ASP133
|
4.4
|
68.7
|
1.0
|
|
CA
|
C:GLN135
|
4.5
|
87.5
|
1.0
|
|
N
|
C:ASN137
|
4.5
|
64.9
|
1.0
|
|
CA
|
C:ASP131
|
4.6
|
76.7
|
1.0
|
|
C
|
C:ASP131
|
4.6
|
78.1
|
1.0
|
|
HG3
|
C:GLU140
|
4.6
|
67.2
|
1.0
|
|
HB3
|
C:ASP133
|
4.7
|
70.3
|
1.0
|
|
HG2
|
C:GLU140
|
4.7
|
67.3
|
1.0
|
|
N
|
C:GLY134
|
4.7
|
72.9
|
1.0
|
|
HB3
|
C:ASP131
|
4.7
|
79.6
|
1.0
|
|
CA
|
C:ASP133
|
4.7
|
71.8
|
1.0
|
|
C
|
C:VAL136
|
4.9
|
61.5
|
1.0
|
|
HB3
|
C:ASN137
|
4.9
|
74.6
|
1.0
|
|
HG3
|
C:GLN135
|
4.9
|
95.0
|
1.0
|
|
HB2
|
C:GLU140
|
4.9
|
66.5
|
1.0
|
|
Reference:
O.Prakash,
N.Gupta,
A.Milburn,
L.Mccormick,
V.Deugi,
P.Fisch,
J.Wyles,
N.L.Thomas,
S.Antonyuk,
C.Dart,
N.Helassa.
Calmodulin Variant E140G Associated with Long Qt Syndrome Impairs Camkii Delta Autophosphorylation and L-Type Calcium Channel (Ca V 1.2) Inactivation. J.Biol.Chem. 02777 2022.
ISSN: ESSN 1083-351X
PubMed: 36496072
DOI: 10.1016/J.JBC.2022.102777
Page generated: Fri Jul 19 06:34:41 2024
|
