Calcium in PDB 8d1o: HBEST1_345 CA2+-Bound Open State

The binding sites of Calcium atom in the HBEST1_345 CA2+-Bound Open State (pdb code 8d1o). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the HBEST1_345 CA2+-Bound Open State, PDB code: 8d1o:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the HBEST1_345 CA2+-Bound Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of HBEST1_345 CA2+-Bound Open State within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca607 b:54.0 occ:1.00 OD2 E:ASP301 2.1 56.7 1.0 OD2 E:ASP304 2.4 46.9 1.0 O E:GLN293 2.4 61.1 1.0 O E:ASN296 2.4 58.1 1.0 O A:ALA10 2.5 51.9 1.0 OD1 E:ASP304 2.7 68.9 1.0 CG E:ASP304 2.9 59.2 1.0 CG E:ASP301 3.3 54.0 1.0 C E:GLN293 3.5 44.2 1.0 C E:ASN296 3.6 48.3 1.0 C A:ALA10 3.6 60.0 1.0 CB E:ASP301 3.9 49.8 1.0 CA E:GLN293 4.0 49.2 1.0 CA A:ASN11 4.2 56.4 1.0 N A:ASN11 4.3 54.1 1.0 OD1 E:ASP301 4.3 82.7 1.0 CA E:PRO297 4.3 43.4 1.0 N E:PRO297 4.4 50.6 1.0 CB E:ASP304 4.4 51.3 1.0 N E:GLY299 4.4 46.9 1.0 CA E:ASN296 4.4 47.0 1.0 O E:GLU292 4.5 73.9 1.0 O A:VAL9 4.5 60.2 1.0 N E:ASN296 4.5 46.1 1.0 CA E:GLY299 4.5 49.0 1.0 CG E:GLN293 4.5 66.1 1.0 CA A:ALA10 4.6 58.9 1.0 NE2 E:GLN293 4.6 87.0 1.0 N E:LEU294 4.6 50.0 1.0 CB E:ASN296 4.7 46.0 1.0 N A:ALA12 4.7 51.7 1.0 C E:PRO297 4.7 48.0 1.0 C A:ASN11 4.8 55.5 1.0 N E:ASP301 4.9 56.5 1.0 CB E:GLN293 4.9 61.8 1.0 OD1 A:ASN11 4.9 98.5 1.0 N E:PHE298 5.0 48.5 1.0

Calcium binding site 2 out of 5 in the HBEST1_345 CA2+-Bound Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of HBEST1_345 CA2+-Bound Open State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca408 b:54.0 occ:1.00 OD2 A:ASP301 2.1 56.7 1.0 OD2 A:ASP304 2.4 46.9 1.0 O A:GLN293 2.4 61.1 1.0 O A:ASN296 2.4 58.1 1.0 O B:ALA10 2.5 51.9 1.0 OD1 A:ASP304 2.7 68.9 1.0 CG A:ASP304 2.9 59.2 1.0 CG A:ASP301 3.3 54.0 1.0 C A:GLN293 3.5 44.2 1.0 C A:ASN296 3.6 48.3 1.0 C B:ALA10 3.6 60.0 1.0 CB A:ASP301 3.9 49.8 1.0 CA A:GLN293 4.0 49.2 1.0 CA B:ASN11 4.2 56.4 1.0 N B:ASN11 4.3 54.1 1.0 OD1 A:ASP301 4.3 82.7 1.0 CA A:PRO297 4.3 43.4 1.0 N A:PRO297 4.4 50.6 1.0 CB A:ASP304 4.4 51.3 1.0 N A:GLY299 4.4 46.9 1.0 CA A:ASN296 4.4 47.0 1.0 O A:GLU292 4.5 73.9 1.0 O B:VAL9 4.5 60.2 1.0 N A:ASN296 4.5 46.1 1.0 CA A:GLY299 4.5 49.0 1.0 CG A:GLN293 4.5 66.1 1.0 CA B:ALA10 4.6 58.9 1.0 NE2 A:GLN293 4.6 87.0 1.0 N A:LEU294 4.6 50.0 1.0 CB A:ASN296 4.7 46.0 1.0 N B:ALA12 4.7 51.7 1.0 C A:PRO297 4.7 48.0 1.0 C B:ASN11 4.8 55.5 1.0 N A:ASP301 4.9 56.5 1.0 CB A:GLN293 4.9 61.8 1.0 OD1 B:ASN11 4.9 98.5 1.0 N A:PHE298 5.0 48.5 1.0

Calcium binding site 3 out of 5 in the HBEST1_345 CA2+-Bound Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of HBEST1_345 CA2+-Bound Open State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca408 b:54.0 occ:1.00 OD2 B:ASP301 2.1 56.7 1.0 OD2 B:ASP304 2.4 46.9 1.0 O B:GLN293 2.4 61.1 1.0 O B:ASN296 2.4 58.1 1.0 O C:ALA10 2.5 51.9 1.0 OD1 B:ASP304 2.7 68.9 1.0 CG B:ASP304 2.9 59.2 1.0 CG B:ASP301 3.3 54.0 1.0 C B:GLN293 3.5 44.2 1.0 C B:ASN296 3.6 48.3 1.0 C C:ALA10 3.6 60.0 1.0 CB B:ASP301 3.9 49.8 1.0 CA B:GLN293 4.0 49.2 1.0 CA C:ASN11 4.2 56.4 1.0 N C:ASN11 4.3 54.1 1.0 OD1 B:ASP301 4.3 82.7 1.0 CA B:PRO297 4.3 43.4 1.0 N B:PRO297 4.4 50.6 1.0 CB B:ASP304 4.4 51.3 1.0 N B:GLY299 4.4 46.9 1.0 CA B:ASN296 4.4 47.0 1.0 O B:GLU292 4.5 73.9 1.0 O C:VAL9 4.5 60.2 1.0 N B:ASN296 4.5 46.1 1.0 CA B:GLY299 4.5 49.0 1.0 CG B:GLN293 4.5 66.1 1.0 CA C:ALA10 4.6 58.9 1.0 NE2 B:GLN293 4.6 87.0 1.0 N B:LEU294 4.6 50.0 1.0 CB B:ASN296 4.7 46.0 1.0 N C:ALA12 4.7 51.7 1.0 C B:PRO297 4.7 48.0 1.0 C C:ASN11 4.8 55.5 1.0 N B:ASP301 4.9 56.5 1.0 CB B:GLN293 4.9 61.8 1.0 OD1 C:ASN11 4.9 98.5 1.0 N B:PHE298 5.0 48.5 1.0

Calcium binding site 4 out of 5 in the HBEST1_345 CA2+-Bound Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of HBEST1_345 CA2+-Bound Open State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca408 b:54.0 occ:1.00 OD2 C:ASP301 2.1 56.7 1.0 OD2 C:ASP304 2.4 46.9 1.0 O C:GLN293 2.4 61.1 1.0 O C:ASN296 2.4 58.1 1.0 O D:ALA10 2.5 51.9 1.0 OD1 C:ASP304 2.7 68.9 1.0 CG C:ASP304 2.9 59.2 1.0 CG C:ASP301 3.3 54.0 1.0 C C:GLN293 3.5 44.2 1.0 C C:ASN296 3.6 48.3 1.0 C D:ALA10 3.6 60.0 1.0 CB C:ASP301 3.9 49.8 1.0 CA C:GLN293 4.0 49.2 1.0 CA D:ASN11 4.2 56.4 1.0 N D:ASN11 4.3 54.1 1.0 OD1 C:ASP301 4.3 82.7 1.0 CA C:PRO297 4.3 43.4 1.0 N C:PRO297 4.4 50.6 1.0 CB C:ASP304 4.4 51.3 1.0 N C:GLY299 4.4 46.9 1.0 CA C:ASN296 4.4 47.0 1.0 O C:GLU292 4.5 73.9 1.0 O D:VAL9 4.5 60.2 1.0 N C:ASN296 4.5 46.1 1.0 CA C:GLY299 4.5 49.0 1.0 CG C:GLN293 4.5 66.1 1.0 CA D:ALA10 4.6 58.9 1.0 NE2 C:GLN293 4.6 87.0 1.0 N C:LEU294 4.6 50.0 1.0 CB C:ASN296 4.7 46.0 1.0 N D:ALA12 4.7 51.7 1.0 C C:PRO297 4.7 48.0 1.0 C D:ASN11 4.8 55.5 1.0 N C:ASP301 4.9 56.5 1.0 CB C:GLN293 4.9 61.8 1.0 OD1 D:ASN11 4.9 98.5 1.0 N C:PHE298 5.0 48.5 1.0

Calcium binding site 5 out of 5 in the HBEST1_345 CA2+-Bound Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of HBEST1_345 CA2+-Bound Open State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca408 b:54.0 occ:1.00 OD2 D:ASP301 2.1 56.7 1.0 OD2 D:ASP304 2.4 46.9 1.0 O D:GLN293 2.4 61.1 1.0 O D:ASN296 2.4 58.1 1.0 O E:ALA10 2.5 51.9 1.0 OD1 D:ASP304 2.7 68.9 1.0 CG D:ASP304 2.9 59.2 1.0 CG D:ASP301 3.3 54.0 1.0 C D:GLN293 3.5 44.2 1.0 C D:ASN296 3.6 48.3 1.0 C E:ALA10 3.6 60.0 1.0 CB D:ASP301 3.9 49.8 1.0 CA D:GLN293 4.0 49.2 1.0 CA E:ASN11 4.2 56.4 1.0 N E:ASN11 4.3 54.1 1.0 OD1 D:ASP301 4.3 82.7 1.0 CA D:PRO297 4.3 43.4 1.0 N D:PRO297 4.4 50.6 1.0 CB D:ASP304 4.4 51.3 1.0 N D:GLY299 4.4 46.9 1.0 CA D:ASN296 4.4 47.0 1.0 O D:GLU292 4.5 73.9 1.0 O E:VAL9 4.5 60.2 1.0 N D:ASN296 4.5 46.1 1.0 CA D:GLY299 4.5 49.0 1.0 CG D:GLN293 4.5 66.1 1.0 CA E:ALA10 4.6 58.9 1.0 NE2 D:GLN293 4.6 87.0 1.0 N D:LEU294 4.6 50.0 1.0 CB D:ASN296 4.7 46.0 1.0 N E:ALA12 4.7 51.7 1.0 C D:PRO297 4.7 48.0 1.0 C E:ASN11 4.8 55.5 1.0 N D:ASP301 4.9 56.5 1.0 CB D:GLN293 4.9 61.8 1.0 OD1 E:ASN11 4.9 98.5 1.0 N D:PHE298 5.0 48.5 1.0

A.P.Owji, J.Wang, A.Kittredge, Z.Clark, Y.Zhang, W.A.Hendrickson, T.Yang. Structures and Gating Mechanisms of Human Bestrophin Anion Channels. Nat Commun V. 13 3836 2022.
ISSN: ESSN 2041-1723
PubMed: 35789156
DOI: 10.1038/S41467-022-31437-7