Calcium in PDB 8ecy: Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex

Enzymatic activity of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex

All present enzymatic activity of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex:
2.3.1.225; 6.3.1.2;

Other elements in 8ecy:

The structure of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex also contains other interesting chemical elements:

Chlorine (Cl) 11 atoms
Manganese (Mn) 20 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex (pdb code 8ecy). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex, PDB code: 8ecy:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in 8ecy

Go back to Calcium Binding Sites List in 8ecy
Calcium binding site 1 out of 5 in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Ca501

b:26.6
occ:1.00
 O E:ASN296 2.4 44.9 1.0
O C:HOH609 2.5 50.0 1.0
O E:GLN293 2.5 54.4 1.0
OD2 E:ASP301 2.6 54.3 1.0
O C:ALA10 2.7 56.9 1.0
OD2 E:ASP304 2.7 51.7 1.0
OD1 E:ASP304 2.8 53.4 1.0
CG E:ASP304 3.1 45.2 1.0
C E:ASN296 3.4 34.0 1.0
CG E:ASP301 3.5 56.1 1.0
C E:GLN293 3.6 48.8 1.0
C C:ALA10 3.7 56.7 1.0
CB E:ASP301 4.0 55.5 1.0
CA E:GLN293 4.1 47.6 1.0
CA C:LYS11 4.2 66.1 1.0
CA E:PRO297 4.2 36.1 1.0
N E:PRO297 4.3 37.4 1.0
O C:VAL9 4.3 55.0 1.0
CA E:ASN296 4.3 37.7 1.0
N C:LYS11 4.3 63.7 1.0
N E:ASN296 4.3 41.4 1.0
OD1 E:ASP301 4.5 62.2 1.0
N E:GLY299 4.5 49.8 1.0
O E:GLU292 4.6 52.3 1.0
CB E:ASN296 4.6 41.2 1.0
CG E:GLN293 4.6 57.8 1.0
CB E:ASP304 4.6 47.5 1.0
CA C:ALA10 4.7 53.0 1.0
CA E:GLY299 4.7 54.7 1.0
N E:LEU294 4.7 45.0 1.0
C C:LYS11 4.7 70.0 1.0
N C:ALA12 4.8 71.4 1.0
C E:PRO297 4.8 35.3 1.0
N E:ASP301 4.9 57.2 1.0

Calcium binding site 2 out of 5 in 8ecy

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Calcium binding site 2 out of 5 in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca501

b:29.3
occ:1.00
 O C:ASN296 2.4 44.9 1.0
O C:GLN293 2.5 54.4 1.0
OD2 C:ASP301 2.6 54.3 1.0
O G:ALA10 2.7 56.9 1.0
OD2 C:ASP304 2.8 51.7 1.0
OD1 C:ASP304 2.9 53.4 1.0
CG C:ASP304 3.2 45.2 1.0
C C:ASN296 3.4 34.0 1.0
C C:GLN293 3.6 48.8 1.0
CG C:ASP301 3.6 56.1 1.0
C G:ALA10 3.7 56.7 1.0
CB C:ASP301 4.1 55.5 1.0
CA C:GLN293 4.1 47.6 1.0
CA G:LYS11 4.2 66.1 1.0
O G:VAL9 4.2 55.0 1.0
N C:PRO297 4.3 37.4 1.0
CA C:PRO297 4.3 36.1 1.0
CA C:ASN296 4.3 37.7 1.0
N C:ASN296 4.3 41.4 1.0
N G:LYS11 4.3 63.7 1.0
O C:GLU292 4.5 52.3 1.0
OD1 C:ASP301 4.5 62.2 1.0
CB C:ASN296 4.6 41.2 1.0
N C:GLY299 4.6 49.8 1.0
CG C:GLN293 4.6 57.8 1.0
CA G:ALA10 4.7 53.0 1.0
N C:LEU294 4.7 45.0 1.0
CB C:ASP304 4.7 47.5 1.0
C G:LYS11 4.7 70.0 1.0
N G:ALA12 4.7 71.4 1.0
CA C:GLY299 4.8 54.7 1.0
C C:PRO297 4.8 35.3 1.0
N C:ASP301 4.9 57.2 1.0
CB C:GLN293 5.0 51.0 1.0

Calcium binding site 3 out of 5 in 8ecy

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Calcium binding site 3 out of 5 in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Ca501

b:26.2
occ:1.00
 O G:ASN296 2.4 44.9 1.0
OD2 G:ASP301 2.6 54.3 1.0
O G:GLN293 2.6 54.4 1.0
O K:ALA10 2.6 56.9 1.0
OD2 G:ASP304 2.8 51.7 1.0
OD1 G:ASP304 3.0 53.4 1.0
CG G:ASP304 3.3 45.2 1.0
C G:ASN296 3.5 34.0 1.0
C K:ALA10 3.5 56.7 1.0
CG G:ASP301 3.6 56.1 1.0
C G:GLN293 3.6 48.8 1.0
CA K:LYS11 4.0 66.1 1.0
CB G:ASP301 4.1 55.5 1.0
O K:VAL9 4.1 55.0 1.0
CA G:GLN293 4.1 47.6 1.0
N K:LYS11 4.2 63.7 1.0
CA G:ASN296 4.3 37.7 1.0
N G:ASN296 4.3 41.4 1.0
N G:PRO297 4.3 37.4 1.0
CA G:PRO297 4.4 36.1 1.0
O G:GLU292 4.5 52.3 1.0
OD1 G:ASP301 4.5 62.2 1.0
CB G:ASN296 4.5 41.2 1.0
CA K:ALA10 4.5 53.0 1.0
N G:GLY299 4.6 49.8 1.0
C K:LYS11 4.6 70.0 1.0
N K:ALA12 4.6 71.4 1.0
CG G:GLN293 4.7 57.8 1.0
CA G:GLY299 4.7 54.7 1.0
N G:LEU294 4.8 45.0 1.0
CB G:ASP304 4.8 47.5 1.0
C G:PRO297 4.9 35.3 1.0
N G:ASP301 5.0 57.2 1.0

Calcium binding site 4 out of 5 in 8ecy

Go back to Calcium Binding Sites List in 8ecy
Calcium binding site 4 out of 5 in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Ca501

b:25.6
occ:1.00
 O K:ASN296 2.4 44.9 1.0
O K:GLN293 2.5 54.4 1.0
OD2 K:ASP301 2.6 54.3 1.0
OD2 K:ASP304 2.7 51.7 1.0
OD1 K:ASP304 2.8 53.4 1.0
O N:ALA10 2.8 56.9 1.0
CG K:ASP304 3.1 45.2 1.0
C K:ASN296 3.5 34.0 1.0
CG K:ASP301 3.5 56.1 1.0
C K:GLN293 3.6 48.8 1.0
C N:ALA10 3.8 56.7 1.0
CB K:ASP301 4.0 55.5 1.0
CA K:GLN293 4.1 47.6 1.0
CA K:PRO297 4.2 36.1 1.0
CA N:LYS11 4.2 66.1 1.0
N K:PRO297 4.3 37.4 1.0
CA K:ASN296 4.4 37.7 1.0
O N:VAL9 4.4 55.0 1.0
N K:ASN296 4.4 41.4 1.0
N N:LYS11 4.4 63.7 1.0
OD1 K:ASP301 4.5 62.2 1.0
N K:GLY299 4.5 49.8 1.0
CG K:GLN293 4.6 57.8 1.0
CB K:ASP304 4.6 47.5 1.0
O K:GLU292 4.6 52.3 1.0
CB K:ASN296 4.7 41.2 1.0
N K:LEU294 4.7 45.0 1.0
CA K:GLY299 4.7 54.7 1.0
C K:PRO297 4.7 35.3 1.0
CA N:ALA10 4.8 53.0 1.0
N N:ALA12 4.8 71.4 1.0
C N:LYS11 4.8 70.0 1.0
N K:ASP301 4.9 57.2 1.0
CB K:GLN293 5.0 51.0 1.0

Calcium binding site 5 out of 5 in 8ecy

Go back to Calcium Binding Sites List in 8ecy
Calcium binding site 5 out of 5 in the Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Cryoem Structure of Bovine Bestrophin-2 and Glutamine Synthetase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
N:Ca501

b:31.9
occ:1.00
 O N:ASN296 2.4 44.9 1.0
O N:GLN293 2.5 54.4 1.0
OD2 N:ASP301 2.6 54.3 1.0
O E:ALA10 2.7 56.9 1.0
OD2 N:ASP304 2.8 51.7 1.0
OD1 N:ASP304 2.9 53.4 1.0
CG N:ASP304 3.2 45.2 1.0
C N:ASN296 3.4 34.0 1.0
C N:GLN293 3.5 48.8 1.0
CG N:ASP301 3.6 56.1 1.0
C E:ALA10 3.7 56.7 1.0
CA N:GLN293 4.0 47.6 1.0
CB N:ASP301 4.1 55.5 1.0
CA E:LYS11 4.2 66.1 1.0
O E:VAL9 4.2 55.0 1.0
N N:PRO297 4.3 37.4 1.0
N N:ASN296 4.3 41.4 1.0
CA N:PRO297 4.3 36.1 1.0
CA N:ASN296 4.3 37.7 1.0
N E:LYS11 4.3 63.7 1.0
O N:GLU292 4.5 52.3 1.0
OD1 N:ASP301 4.5 62.2 1.0
CB N:ASN296 4.6 41.2 1.0
CG N:GLN293 4.6 57.8 1.0
N N:GLY299 4.6 49.8 1.0
N N:LEU294 4.6 45.0 1.0
CA E:ALA10 4.7 53.0 1.0
C E:LYS11 4.7 70.0 1.0
N E:ALA12 4.7 71.4 1.0
CB N:ASP304 4.7 47.5 1.0
CA N:GLY299 4.8 54.7 1.0
C N:PRO297 4.8 35.3 1.0
CB N:GLN293 5.0 51.0 1.0
N N:ASP301 5.0 57.2 1.0

Reference:

A.P.Owji, K.Yu, A.Kittredge, J.Wang, Y.Zhang, T.Yang. Bestrophin-2 and Glutamine Synthetase Form A Complex For Glutamate Release. Nature V. 611 180 2022.
ISSN: ESSN 1476-4687
PubMed: 36289327
DOI: 10.1038/S41586-022-05373-X
Page generated: Tue Apr 4 19:37:04 2023

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