Calcium in PDB 8egw: Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)

The structure of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3), PDB code: 8egw was solved by E.Medina, V.C.Luca, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.08 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	88.66, 61.37, 100.966, 90, 112.74, 90
R / Rfree (%)	19 / 23.5

The structure of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) also contains other interesting chemical elements:

Arsenic

(As)

3 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 19;

Binding sites:

The binding sites of Calcium atom in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) (pdb code 8egw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 19 binding sites of Calcium where determined in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3), PDB code: 8egw:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca402 b:72.5 occ:1.00 OD2 A:ASP250 2.2 56.9 1.0 OE1 A:GLU216 2.2 43.4 1.0 OD1 A:ASP214 2.3 66.6 1.0 OE1 A:GLU154 2.4 35.7 1.0 O A:HOH542 2.4 44.7 1.0 NE2 A:HIS155 2.5 56.3 1.0 CG A:ASP250 3.1 55.2 1.0 OD1 A:ASP250 3.3 52.3 1.0 CD A:GLU154 3.3 42.6 1.0 CD2 A:HIS155 3.3 54.7 1.0 CG A:ASP214 3.4 63.7 1.0 CD A:GLU216 3.5 53.5 1.0 CE1 A:HIS155 3.6 56.0 1.0 OE2 A:GLU154 3.6 40.5 1.0 CE1 A:HIS251 4.0 45.2 1.0 OD2 A:ASP214 4.0 74.7 1.0 OE2 A:GLU216 4.1 42.1 1.0 CA A:CA404 4.2 43.9 1.0 N A:ARG215 4.4 49.1 1.0 CA A:ASP214 4.4 50.1 1.0 CB A:ASP214 4.4 53.5 1.0 N A:GLU216 4.5 51.8 1.0 CG A:HIS155 4.5 53.0 1.0 CB A:GLU216 4.5 46.9 1.0 CB A:ASP250 4.5 47.8 1.0 CG A:GLU154 4.6 31.9 1.0 CG A:GLU216 4.6 50.3 1.0 ND1 A:HIS155 4.6 57.4 1.0 C A:ASP214 4.7 45.9 1.0 ND1 A:HIS251 4.7 51.7 1.0 NE2 A:HIS251 5.0 55.3 1.0 CB A:GLU154 5.0 34.3 1.0

Calcium binding site 2 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca403 b:42.9 occ:1.00 OD2 A:ASP283 2.2 60.2 1.0 OD1 A:ASN249 2.3 51.1 1.0 O A:ASN287 2.4 40.4 1.0 OD1 A:ASP281 2.4 43.4 1.0 O A:HIS251 2.5 46.6 1.0 OD2 A:ASP336 2.5 49.9 1.0 OD2 A:ASP281 2.7 45.3 1.0 CG A:ASP281 2.9 45.6 1.0 CG A:ASP283 3.2 57.5 1.0 C A:ASN287 3.5 49.4 1.0 CG A:ASN249 3.5 46.1 1.0 CG A:ASP336 3.6 48.5 1.0 C A:HIS251 3.6 45.9 1.0 CB A:ASP283 3.7 43.3 1.0 CB A:ASP336 4.0 33.2 1.0 N A:HIS251 4.2 44.3 1.0 ND2 A:ASN249 4.2 48.7 1.0 CA A:HIS251 4.3 45.4 1.0 CA A:ASN287 4.3 46.6 1.0 OD1 A:ASP283 4.3 53.9 1.0 CB A:HIS251 4.4 48.3 1.0 CB A:ASP281 4.4 31.7 1.0 N A:GLY288 4.4 49.5 1.0 CB A:ASN287 4.4 41.8 1.0 CA A:GLY288 4.5 40.3 1.0 N A:ALA252 4.5 41.6 1.0 OD1 A:ASP336 4.6 44.1 1.0 CA A:ALA252 4.6 43.4 1.0 CB A:ASN249 4.6 38.2 1.0 CA A:ASN249 4.6 42.4 1.0 N A:ASP283 4.7 53.8 1.0 C A:ASN249 4.8 43.5 1.0 CA A:ASP283 4.8 43.5 1.0

Calcium binding site 3 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca404 b:43.9 occ:1.00 OE2 A:GLU216 2.2 42.1 1.0 O A:ILE248 2.3 38.3 1.0 OD1 A:ASP250 2.3 52.3 1.0 OE2 A:GLU154 2.3 40.5 1.0 OD1 A:ASP247 2.3 44.7 1.0 OD1 A:ASP283 2.5 53.9 1.0 CD A:GLU216 3.1 53.5 1.0 OE1 A:GLU216 3.3 43.4 1.0 CD A:GLU154 3.4 42.6 1.0 CG A:ASP283 3.4 57.5 1.0 CG A:ASP247 3.5 51.8 1.0 C A:ILE248 3.5 49.0 1.0 CG A:ASP250 3.5 55.2 1.0 N A:ILE248 3.8 40.6 1.0 OE1 A:GLU154 3.9 35.7 1.0 CB A:ASP283 4.0 43.3 1.0 N A:ASP250 4.1 39.4 1.0 OD2 A:ASP250 4.1 56.9 1.0 OD2 A:ASP247 4.1 45.6 1.0 NH1 A:ARG215 4.1 67.7 1.0 ND1 A:HIS251 4.2 51.7 1.0 CA A:CA402 4.2 72.5 1.0 CA A:ILE248 4.3 57.1 1.0 CA A:ASP283 4.3 43.5 1.0 OD2 A:ASP283 4.3 60.2 1.0 N A:ASN249 4.5 36.2 1.0 CB A:ASP247 4.5 38.3 1.0 CA A:ASP247 4.5 36.3 1.0 C A:ASP247 4.5 46.4 1.0 CG A:GLU216 4.5 50.3 1.0 CG1 A:ILE248 4.5 58.4 1.0 CE1 A:HIS251 4.6 45.2 1.0 CB A:ASP250 4.6 47.8 1.0 CG A:GLU154 4.7 31.9 1.0 CA A:ASN249 4.7 42.4 1.0 CA A:ASP250 4.8 44.7 1.0 NE A:ARG215 4.9 73.2 1.0 C A:ASN249 4.9 43.5 1.0 CZ A:ARG215 5.0 73.6 1.0

Calcium binding site 4 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca405 b:57.1 occ:1.00 O A:HIS139 2.2 55.7 1.0 O A:LEU175 2.3 50.2 1.0 OD1 A:ASN137 2.3 76.3 1.0 OD2 A:ASP229 2.5 45.0 1.0 OD2 A:ASP171 2.5 80.0 1.0 OD2 A:ASP169 2.5 63.1 1.0 OD1 A:ASP169 2.5 61.9 1.0 CG A:ASP169 2.9 66.0 1.0 CG A:ASP229 3.4 54.8 1.0 C A:HIS139 3.4 57.2 1.0 CG A:ASN137 3.4 69.6 1.0 CG A:ASP171 3.4 69.2 1.0 C A:LEU175 3.5 51.5 1.0 CB A:ASP229 3.7 57.8 1.0 CB A:ASP171 3.8 59.3 1.0 ND2 A:ASN137 3.9 65.2 1.0 CB A:HIS139 4.2 60.3 1.0 CA A:HIS139 4.2 62.8 1.0 N A:ALA140 4.3 54.8 1.0 N A:GLY176 4.4 54.4 1.0 N A:HIS139 4.4 66.1 1.0 CB A:ASP169 4.4 63.4 1.0 CA A:GLY176 4.4 51.4 1.0 CA A:LEU175 4.4 62.2 1.0 OD1 A:ASP229 4.4 50.7 1.0 CA A:ALA140 4.4 62.0 1.0 OD1 A:ASP171 4.5 70.2 1.0 CB A:LEU175 4.6 64.3 1.0 CB A:ASN137 4.7 57.3 1.0 CD A:PRO141 4.7 58.6 1.0 CA A:ASN137 4.8 57.7 1.0 C A:ALA140 4.8 46.4 1.0 O A:ASN137 4.9 66.7 1.0 C A:GLY176 4.9 57.2 1.0 C A:ASN137 4.9 63.2 1.0 N A:ASP171 4.9 51.0 1.0 N A:PRO141 5.0 56.6 1.0 CA A:ASP171 5.0 56.9 1.0

Calcium binding site 5 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca406 b:56.4 occ:1.00 OE2 A:GLU110 2.2 65.5 1.0 OD1 A:ASP138 2.3 63.9 1.0 O A:ILE136 2.3 47.2 1.0 OD1 A:ASP135 2.4 52.2 1.0 OE1 A:GLU53 2.5 69.4 1.0 OD1 A:ASP171 2.5 70.2 1.0 CD A:GLU110 2.8 61.8 1.0 OE1 A:GLU110 2.9 61.4 1.0 CD A:GLU53 3.3 73.6 1.0 OE2 A:GLU53 3.3 72.0 1.0 CG A:ASP138 3.4 71.4 1.0 CG A:ASP171 3.4 69.2 1.0 C A:ILE136 3.5 62.4 1.0 CG A:ASP135 3.6 71.8 1.0 N A:ILE136 3.9 56.5 1.0 OD2 A:ASP138 4.0 69.6 1.0 ND1 A:HIS139 4.0 74.2 1.0 N A:ASP138 4.1 57.8 1.0 CB A:ASP171 4.1 59.3 1.0 CA A:CA407 4.2 73.8 1.0 CG A:GLU110 4.2 62.7 1.0 OD2 A:ASP171 4.3 80.0 1.0 CA A:ASP171 4.3 56.9 1.0 OD2 A:ASP135 4.3 80.5 1.0 CA A:ILE136 4.3 61.3 1.0 CG1 A:ILE136 4.5 56.3 1.0 N A:ASN137 4.5 64.3 1.0 CE1 A:HIS139 4.5 72.2 1.0 NH1 A:ARG109 4.6 69.0 1.0 CB A:ASP138 4.6 58.1 1.0 CA A:ASP135 4.6 61.5 1.0 C A:ASP135 4.6 62.4 1.0 CA A:ASN137 4.7 57.7 1.0 CB A:ASP135 4.7 67.6 1.0 CG A:GLU53 4.7 75.7 1.0 CA A:ASP138 4.8 58.9 1.0 NE A:ARG109 4.9 71.8 1.0 C A:ASN137 4.9 63.2 1.0 CB A:ARG109 4.9 55.7 1.0 N A:ASP171 5.0 51.0 1.0

Calcium binding site 6 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca407 b:73.8 occ:1.00 OD2 A:ASP138 2.2 69.6 1.0 OE1 A:GLU110 2.3 61.4 1.0 OD1 A:ASP108 2.3 73.3 1.0 OE2 A:GLU53 2.3 72.0 1.0 OE2 A:GLU54 2.5 88.9 1.0 CG A:ASP138 3.2 71.4 1.0 CG A:ASP108 3.3 79.6 1.0 CD A:GLU54 3.4 84.2 1.0 CD A:GLU53 3.4 73.6 1.0 CD A:GLU110 3.5 61.8 1.0 OD1 A:ASP138 3.6 63.9 1.0 CG A:GLU54 3.7 70.7 1.0 OD2 A:ASP108 4.0 74.5 1.0 CB A:ASP108 4.2 71.0 1.0 OE1 A:GLU53 4.2 69.4 1.0 CA A:ASP108 4.2 60.2 1.0 CE1 A:HIS139 4.2 72.2 1.0 CA A:CA406 4.2 56.4 1.0 OE2 A:GLU110 4.3 65.5 1.0 N A:ARG109 4.3 50.6 1.0 CG A:GLU53 4.4 75.7 1.0 CG A:GLU110 4.4 62.7 1.0 OE1 A:GLU54 4.5 89.8 1.0 CB A:ASP138 4.5 58.1 1.0 N A:GLU110 4.5 52.9 1.0 CB A:GLU110 4.5 65.4 1.0 C A:ASP108 4.6 55.2 1.0 ND1 A:HIS139 4.8 74.2 1.0 CB A:GLU53 4.8 71.8 1.0

Calcium binding site 7 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca408 b:122.5 occ:1.00 OD2 A:ASP354 3.3 120.9 1.0 OE2 A:GLU266 3.4 89.3 1.0 O A:HOH600 4.1 75.5 1.0 CG A:ASP354 4.3 117.0 1.0 CD A:GLU266 4.3 82.0 1.0 OE1 A:GLU266 4.5 79.9 1.0 OD1 A:ASP354 4.6 120.3 1.0 CG A:GLU323 4.7 109.5 1.0 OE2 A:GLU323 4.8 134.1 1.0

Calcium binding site 8 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca409 b:120.6 occ:1.00 NH2 A:ARG297 3.3 89.8 1.0 O A:HOH528 4.0 63.1 1.0 O B:VAL141 4.2 49.6 1.0 NE2 A:GLN298 4.2 77.0 1.0 CG1 B:VAL142 4.3 47.1 1.0 O B:HOH736 4.3 60.9 1.0 O B:ILE155 4.3 57.7 1.0 CD1 B:ILE140 4.4 42.2 1.0 CZ A:ARG297 4.5 85.4 1.0 CB B:ILE140 4.6 51.9 1.0 CD A:ARG297 4.8 69.3 1.0 CG2 B:ILE140 4.9 43.8 1.0 OD2 B:ASP157 4.9 63.3 1.0 CG1 B:ILE140 5.0 50.8 1.0

Calcium binding site 9 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca501 b:42.4 occ:1.00 O B:ASN131 2.3 36.8 1.0 OD2 B:ASP163 2.4 46.2 1.0 OD2 B:ASP224 2.4 37.8 1.0 O B:ASN167 2.5 36.8 1.0 OD2 B:ASP161 2.5 37.6 1.0 OD1 B:ASP161 2.5 45.0 1.0 OD1 B:ASN129 2.5 49.7 1.0 CG B:ASP161 2.8 53.6 1.0 CG B:ASP163 3.3 50.7 1.0 C B:ASN131 3.5 44.6 1.0 CG B:ASP224 3.5 53.8 1.0 CG B:ASN129 3.6 60.1 1.0 C B:ASN167 3.7 51.6 1.0 CB B:ASP163 3.7 33.8 1.0 CB B:ASP224 4.0 42.3 1.0 CB B:ASN167 4.2 40.4 1.0 N B:ASN131 4.2 47.0 1.0 ND2 B:ASN129 4.3 32.4 1.0 CA B:ASN131 4.3 41.7 1.0 CB B:ASP161 4.3 43.9 1.0 OD1 B:ASP163 4.4 45.7 1.0 N B:ALA132 4.5 40.0 1.0 CA B:ASN167 4.5 50.1 1.0 CB B:ASN131 4.5 44.0 1.0 OD1 B:ASP224 4.6 50.1 1.0 N B:GLY168 4.6 41.3 1.0 CA B:ASN129 4.6 44.7 1.0 CA B:ALA132 4.7 46.5 1.0 N B:ASP163 4.7 39.5 1.0 CA B:GLY168 4.7 46.4 1.0 CB B:ASN129 4.8 36.2 1.0 C B:ASN129 4.8 48.3 1.0 CA B:ASP163 4.8 39.1 1.0 C B:ALA132 4.9 48.7 1.0

Calcium binding site 10 out of 19 in the Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Complex of FAT4(EC1-4) Bound to DCHS1(EC1-3) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca502 b:42.0 occ:1.00 OD1 B:ASP130 2.3 48.5 1.0 OD1 B:ASP127 2.3 46.5 1.0 OE2 B:GLU99 2.4 52.1 1.0 O B:LEU128 2.5 33.9 1.0 OE2 B:GLU53 2.5 39.4 1.0 OE1 B:GLU99 2.5 45.4 1.0 OD1 B:ASP163 2.5 45.7 1.0 CD B:GLU99 2.7 51.9 1.0 CG B:ASP127 3.3 53.5 1.0 CG B:ASP163 3.4 50.7 1.0 CG B:ASP130 3.5 53.6 1.0 CD B:GLU53 3.6 62.5 1.0 C B:LEU128 3.6 47.0 1.0 OD2 B:ASP127 3.8 44.8 1.0 ND2 B:ASN131 3.8 43.3 1.0 N B:LEU128 3.8 38.5 1.0 CA B:CA503 3.9 51.6 1.0 OE1 B:GLU53 3.9 53.2 1.0 OD2 B:ASP130 4.0 46.8 1.0 CB B:ASP163 4.1 33.8 1.0 N B:ASP130 4.1 45.3 1.0 CG B:GLU99 4.2 49.5 1.0 CA B:LEU128 4.2 50.8 1.0 OD2 B:ASP163 4.3 46.2 1.0 NE B:ARG98 4.3 45.8 1.0 CA B:ASP163 4.4 39.1 1.0 CB B:ASP127 4.5 47.8 1.0 C B:ASP127 4.6 44.4 1.0 CA B:ASP127 4.6 41.2 1.0 CB B:ASP130 4.6 39.1 1.0 N B:ASN129 4.7 47.6 1.0 NH2 B:ARG98 4.7 48.5 1.0 CA B:ASP130 4.8 50.0 1.0 CB B:LEU128 4.8 53.9 1.0 CG B:GLU53 4.9 54.7 1.0 O B:HOH713 4.9 45.8 1.0 N B:ASN131 5.0 47.0 1.0 CA B:ASN129 5.0 44.7 1.0

E.Medina, Y.Easa, D.Sprinzak, V.C.Luca. Structural Basis For Interactions Between the Planar Cell Polarity Cadherins FAT4 and DACHSOUS1 To Be Published.