Calcium in PDB 8sgt: Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)

Calcium Binding Sites:

The binding sites of Calcium atom in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) (pdb code 8sgt). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 6 binding sites of Calcium where determined in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+), PDB code: 8sgt:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6;

Calcium binding site 1 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 1 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1001

b:68.8
occ:1.00
 OD2 A:ASP421 2.1 84.7 1.0
OE2 A:GLU451 2.5 36.6 1.0
OD1 A:ASP421 2.5 84.7 1.0
CG A:ASP421 2.6 84.7 1.0
OE2 A:GLU454 3.0 72.8 1.0
CD A:GLU451 3.6 36.6 1.0
CD A:GLU454 3.9 72.8 1.0
OE1 A:GLU454 4.0 72.8 1.0
CB A:ASP421 4.1 84.7 1.0
ND2 A:ASN417 4.3 97.3 1.0
OE1 A:GLU451 4.4 36.6 1.0
CA A:CA1002 4.4 51.0 1.0
CG A:GLU451 4.6 36.6 1.0
OE2 A:GLU660 4.8 83.0 1.0
N A:ASN417 5.0 97.3 1.0
CA A:ASP421 5.0 84.7 1.0

Calcium binding site 2 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 2 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1002

b:51.0
occ:1.00
 OD1 A:ASP421 2.3 84.7 1.0
OE1 A:GLU451 2.3 36.6 1.0
OE2 A:GLU385 2.6 66.4 1.0
CD A:GLU451 3.2 36.6 1.0
OE2 A:GLU451 3.3 36.6 1.0
CG A:ASP421 3.4 84.7 1.0
CD A:GLU385 3.7 66.4 1.0
OE1 A:GLU454 3.8 72.8 1.0
CB A:ASP421 3.8 84.7 1.0
CA A:CA1004 3.9 47.8 1.0
CA A:ASP421 4.1 84.7 1.0
CG A:GLU385 4.1 66.4 1.0
CA A:CA1001 4.4 68.8 1.0
O A:ILE445 4.4 85.0 1.0
OD2 A:ASP421 4.4 84.7 1.0
OD2 A:ASP447 4.5 56.5 1.0
CG A:GLU451 4.6 36.6 1.0
O A:ASP421 4.6 84.7 1.0
CG2 A:ILE496 4.6 79.1 1.0
O A:SER420 4.7 97.5 1.0
OD1 A:ASP447 4.7 56.5 1.0
OE1 A:GLU385 4.7 66.4 1.0
CD A:GLU454 4.9 72.8 1.0
C A:ASP421 4.9 84.7 1.0
CB A:GLU451 5.0 36.6 1.0

Calcium binding site 3 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 3 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1003

b:81.1
occ:1.00
 OE1 A:GLU385 2.2 66.4 1.0
OD1 A:ASP500 2.4 44.8 1.0
OD1 A:ASP446 2.5 66.7 1.0
O A:ASP447 2.5 56.5 1.0
OD2 A:ASP500 2.6 44.8 1.0
CG A:ASP500 2.8 44.8 1.0
CD A:GLU385 3.5 66.4 1.0
CG A:ASP446 3.5 66.7 1.0
C A:ASP447 3.7 56.5 1.0
OD1 A:ASP499 3.8 56.3 1.0
OD2 A:ASP446 3.9 66.7 1.0
CA A:CA1004 4.1 47.8 1.0
OD2 A:ASP499 4.1 56.3 1.0
N A:ASP447 4.1 56.5 1.0
CG A:ASP499 4.2 56.3 1.0
CB A:ASP500 4.2 44.8 1.0
CG A:GLU385 4.3 66.4 1.0
CB A:GLU385 4.3 66.4 1.0
OE2 A:GLU385 4.4 66.4 1.0
OD1 A:ASP498 4.5 54.7 1.0
CZ A:PHE621 4.5 55.5 1.0
CE1 A:PHE621 4.5 55.5 1.0
CA A:ASP447 4.6 56.5 1.0
N A:ASP448 4.6 41.1 1.0
CA A:ASP448 4.7 41.1 1.0
OD1 A:ASP447 4.8 56.5 1.0
N A:ASP500 4.8 44.8 1.0
CA A:ASP500 4.8 44.8 1.0
CB A:ASP446 4.8 66.7 1.0
N A:ASP499 4.9 56.3 1.0
C A:ASP499 5.0 56.3 1.0

Calcium binding site 4 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 4 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1004

b:47.8
occ:1.00
 OE2 A:GLU385 2.2 66.4 1.0
OD2 A:ASP500 2.5 44.8 1.0
OD1 A:ASP447 2.6 56.5 1.0
O A:ILE449 2.6 34.8 1.0
OE1 A:GLU451 2.7 36.6 1.0
OE1 A:GLU385 2.7 66.4 1.0
OD1 A:ASP498 2.8 54.7 1.0
CD A:GLU385 2.8 66.4 1.0
CD A:GLU451 3.6 36.6 1.0
CG A:ASP500 3.7 44.8 1.0
CG A:ASP447 3.8 56.5 1.0
C A:ILE449 3.8 34.8 1.0
CG A:ASP498 3.9 54.7 1.0
CA A:CA1002 3.9 51.0 1.0
CG A:GLU451 4.0 36.6 1.0
CA A:CA1003 4.1 81.1 1.0
O A:ASP447 4.1 56.5 1.0
N A:ILE449 4.1 34.8 1.0
CG A:GLU385 4.3 66.4 1.0
OD2 A:ASP447 4.3 56.5 1.0
CB A:ASP500 4.4 44.8 1.0
C A:ASP447 4.5 56.5 1.0
CA A:ILE449 4.5 34.8 1.0
CB A:GLU451 4.5 36.6 1.0
OE2 A:GLU451 4.6 36.6 1.0
CB A:ASP498 4.7 54.7 1.0
OD1 A:ASP500 4.7 44.8 1.0
N A:ASP447 4.7 56.5 1.0
OD2 A:ASP498 4.7 54.7 1.0
N A:GLU451 4.8 36.6 1.0
CB A:ILE449 4.8 34.8 1.0
C A:ASP448 4.9 41.1 1.0
N A:PHE450 4.9 31.2 1.0
CB A:ASP447 4.9 56.5 1.0
CA A:ASP447 4.9 56.5 1.0
N A:ASP448 5.0 41.1 1.0
C A:PHE450 5.0 31.2 1.0

Calcium binding site 5 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 5 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1005

b:101.2
occ:1.00
 OD1 A:ASP578 2.4 116.4 1.0
OE1 A:GLU516 2.5 90.3 1.0
OE2 A:GLU683 2.5 122.6 1.0
OE1 A:GLU683 2.6 122.6 1.0
O A:GLU580 2.7 154.3 1.0
CD A:GLU683 2.9 122.6 1.0
OE2 A:GLU516 3.2 90.3 1.0
CD A:GLU516 3.2 90.3 1.0
CG A:ASP578 3.5 116.4 1.0
O A:ASP578 3.8 116.4 1.0
C A:GLU580 3.9 154.3 1.0
OD2 A:ASP578 4.0 116.4 1.0
N A:GLU582 4.3 166.1 1.0
CG A:GLU683 4.4 122.6 1.0
C A:ASP578 4.5 116.4 1.0
CA A:TYR581 4.5 186.6 1.0
N A:ASP578 4.7 116.4 1.0
CG A:GLU516 4.7 90.3 1.0
N A:TYR581 4.7 186.6 1.0
CB A:ASP578 4.8 116.4 1.0
CA A:ASP578 4.9 116.4 1.0
CB A:GLU582 4.9 166.1 1.0
N A:GLU580 4.9 154.3 1.0
C A:TYR581 4.9 186.6 1.0
CA A:GLU580 5.0 154.3 1.0

Calcium binding site 6 out of 6 in 8sgt

Go back to Calcium Binding Sites List in 8sgt
Calcium binding site 6 out of 6 in the Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Cryo-Em Structure of Human NCX1 in CA2+ Bound, Activated State (Group II in the Presence of 0.5 Mm CA2+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1006

b:183.7
occ:1.00
 OD2 A:ASP578 2.7 116.4 1.0
CG A:ASP578 3.2 116.4 1.0
CG A:ASP552 3.3 78.1 1.0
OD1 A:ASP552 3.4 78.1 1.0
OD2 A:ASP552 3.4 78.1 1.0
OE2 A:GLU516 3.8 90.3 1.0
OD1 A:ASP578 3.8 116.4 1.0
CB A:ASP578 3.8 116.4 1.0
CB A:ASP552 3.9 78.1 1.0
OE1 A:GLU582 4.4 166.1 1.0
CA A:ASP552 4.5 78.1 1.0
O A:ILE576 4.6 92.3 1.0
O A:GLU551 4.6 72.3 1.0
NZ A:LYS585 4.7 103.8 1.0
CD A:LYS585 4.7 103.8 1.0
N A:ASP578 4.9 116.4 1.0
CE A:LYS585 5.0 103.8 1.0
CA A:ASP578 5.0 116.4 1.0

Reference:

J.Xue, Y.Han, W.Zeng, Y.Jiang. Structural Mechanisms of Human Cardiac Sodium Calcium Exchanger NCX1 To Be Published.
Page generated: Fri Jul 19 11:27:09 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy