Calcium in PDB 8si3: Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State

All present enzymatic activity of Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State:
2.7.11.1;

The binding sites of Calcium atom in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State (pdb code 8si3). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State, PDB code: 8si3:

Calcium binding site 1 out of 1 in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of TRPM7 in Gdn Detergent in Apo State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1317 b:53.3 occ:1.00 HA3 D:GLY1046 3.0 28.8 1.0 HA3 B:GLY1046 3.1 54.2 1.0 HA3 A:GLY1046 3.1 36.4 1.0 HA3 C:GLY1046 3.1 34.9 1.0 CA D:GLY1046 3.9 28.8 1.0 CA B:GLY1046 3.9 54.2 1.0 CA A:GLY1046 3.9 36.4 1.0 CA C:GLY1046 3.9 34.9 1.0 HA2 D:GLY1046 4.0 28.8 1.0 HA2 B:GLY1046 4.0 54.2 1.0 HA2 A:GLY1046 4.0 36.4 1.0 HA2 C:GLY1046 4.0 34.9 1.0 O D:GLY1046 4.2 28.8 1.0 O B:GLY1046 4.2 54.2 1.0 O C:GLY1046 4.2 34.9 1.0 O A:GLY1046 4.2 36.4 1.0 C D:GLY1046 4.5 28.8 1.0 C B:GLY1046 4.5 54.2 1.0 C C:GLY1046 4.5 34.9 1.0 C A:GLY1046 4.5 36.4 1.0 O D:PHE1045 4.7 28.1 1.0 O B:PHE1045 4.7 66.7 1.0 O A:PHE1045 4.7 32.3 1.0 O C:PHE1045 4.7 26.4 1.0 N D:GLY1046 4.9 28.8 1.0 N B:GLY1046 5.0 54.2 1.0 N A:GLY1046 5.0 36.4 1.0 N C:GLY1046 5.0 34.9 1.0

K.D.Nadezhdin, L.Correia, C.Chamali Narangoda, D.S.Patel, A.Neuberger, T.Gudermann, M.G.Kurnikova, V.Chubanov, A.I.Sobolevsky. Structural Mechanisms of TRPM7 Activation and Inhibition Nat Commun 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-38362-3