Calcium in PDB 8sih: Crystal Structure of PRMT4 with Compound YD1-289

All present enzymatic activity of Crystal Structure of PRMT4 with Compound YD1-289:
2.1.1.319;

The structure of Crystal Structure of PRMT4 with Compound YD1-289, PDB code: 8sih was solved by X.Song, A.Dong, Y.Deng, R.Huang, C.H.Arrowsmith, A.M.Edwards, J.Min, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.38 / 2.35
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	86.582, 86.582, 136.026, 90, 90, 120
R / Rfree (%)	19.6 / 24.6

The binding sites of Calcium atom in the Crystal Structure of PRMT4 with Compound YD1-289 (pdb code 8sih). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of PRMT4 with Compound YD1-289, PDB code: 8sih:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of PRMT4 with Compound YD1-289


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of PRMT4 with Compound YD1-289 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca502 b:97.3 occ:1.00 O A:HOH623 3.2 52.4 1.0 CG A:GLN204 3.4 50.2 1.0 NE2 A:GLN204 3.6 46.9 1.0 O A:PHE200 3.6 47.3 1.0 CD A:GLN204 4.1 48.5 1.0 CB A:PHE200 4.2 44.6 1.0 CD1 A:PHE200 4.3 48.8 1.0 CD1 A:LEU231 4.4 57.2 1.0 C A:PHE200 4.4 41.0 1.0 CA A:PHE200 4.5 46.0 1.0 N A:GLN204 4.6 47.7 1.0 CB A:GLN204 4.7 49.0 1.0 CG A:PHE200 4.7 47.1 1.0 CA A:GLN204 4.8 47.0 1.0 CB A:ALA203 4.8 49.0 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of PRMT4 with Compound YD1-289


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of PRMT4 with Compound YD1-289 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:85.7 occ:1.00 N A:HIS319 3.5 41.2 1.0 CA A:HIS319 3.7 50.0 1.0 O A:SER317 4.0 45.7 1.0 CG A:HIS319 4.0 47.2 1.0 CD2 A:HIS319 4.0 42.5 1.0 ND1 A:HIS319 4.1 50.1 1.0 NE2 A:HIS319 4.1 48.2 1.0 CE1 A:HIS319 4.2 49.6 1.0 CB A:HIS319 4.5 50.5 1.0 C A:PHE318 4.6 44.4 1.0 O A:HOH616 4.9 49.2 1.0 CA A:PHE318 4.9 44.9 1.0 C A:HIS319 4.9 51.7 1.0

X.Song, A.Dong, Y.Deng, R.Huang, C.H.Arrowsmith, A.M.Edwards, J.Min, Structural Genomics Consortium (Sgc). Crystal Structure of PRMT4 with Compound YD1-289 To Be Published.