Calcium in PDB 8tps: NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6)

The binding sites of Calcium atom in the NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6) (pdb code 8tps). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6), PDB code: 8tps:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:63.8 occ:1.00 OE1 A:GLU506 1.6 86.0 1.0 OD1 A:ASP503 2.2 83.6 1.0 OD1 A:ASP539 2.6 88.8 1.0 CD A:GLU506 2.6 99.1 1.0 OE2 A:GLU535 2.7 100.2 1.0 OD2 A:ASP539 2.8 96.2 1.0 OE2 A:GLU506 3.0 99.2 1.0 CG A:ASP539 3.1 87.9 1.0 CG A:ASP503 3.3 88.5 1.0 CD A:GLU535 3.6 102.2 1.0 CG A:GLU535 3.7 90.0 1.0 CG A:GLU506 4.0 91.8 1.0 CB A:ASP503 4.0 75.0 1.0 OH A:TYR188 4.0 76.8 1.0 NZ A:LYS542 4.1 85.8 1.0 OD2 A:ASP503 4.2 86.9 1.0 CA A:ASP503 4.3 77.2 1.0 CB A:ASP539 4.6 71.4 1.0 OE1 A:GLU535 4.8 98.1 1.0 CE A:LYS542 5.0 83.4 1.0

Calcium binding site 2 out of 2 in the NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of NHTMEM16 A444P Mutant in Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+ (Bent TM6) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:63.8 occ:1.00 OE1 B:GLU506 1.6 86.0 1.0 OD1 B:ASP503 2.2 83.6 1.0 OD1 B:ASP539 2.6 88.8 1.0 CD B:GLU506 2.6 99.1 1.0 OE2 B:GLU535 2.7 100.2 1.0 OD2 B:ASP539 2.8 96.2 1.0 OE2 B:GLU506 3.0 99.2 1.0 CG B:ASP539 3.1 87.9 1.0 CG B:ASP503 3.3 88.5 1.0 CD B:GLU535 3.6 102.2 1.0 CG B:GLU535 3.7 90.0 1.0 CG B:GLU506 4.0 91.8 1.0 CB B:ASP503 4.0 75.0 1.0 OH B:TYR188 4.0 76.8 1.0 NZ B:LYS542 4.1 85.8 1.0 OD2 B:ASP503 4.2 86.9 1.0 CA B:ASP503 4.3 77.2 1.0 CB B:ASP539 4.6 71.4 1.0 OE1 B:GLU535 4.8 98.1 1.0 CE B:LYS542 5.0 83.4 1.0

Z.Feng, O.E.Alvarenga, A.Accardi. Structural Basis of Closed Groove Scrambling By A TMEM16 Protein. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 38684930
DOI: 10.1038/S41594-024-01284-9