Calcium in PDB 8w92: Human H Ferritin with 2 Fe(II)/Subunit Loading

All present enzymatic activity of Human H Ferritin with 2 Fe(II)/Subunit Loading:
1.16.3.1;

The structure of Human H Ferritin with 2 Fe(II)/Subunit Loading, PDB code: 8w92 was solved by T.Zhang, R.Jiao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.20 / 2.12
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	182.22, 182.22, 182.22, 90, 90, 90
R / Rfree (%)	16.5 / 20

The structure of Human H Ferritin with 2 Fe(II)/Subunit Loading also contains other interesting chemical elements:

Iron

(Fe)

3 atoms

The binding sites of Calcium atom in the Human H Ferritin with 2 Fe(II)/Subunit Loading (pdb code 8w92). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Human H Ferritin with 2 Fe(II)/Subunit Loading, PDB code: 8w92:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Human H Ferritin with 2 Fe(II)/Subunit Loading


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human H Ferritin with 2 Fe(II)/Subunit Loading within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca204 b:91.6 occ:0.50 NZ A:LYS87 3.6 65.2 1.0 OE1 A:GLN86 3.7 41.5 1.0 CG A:LYS87 4.5 44.0 1.0 CD A:LYS87 4.5 46.5 1.0 CE A:LYS87 4.6 55.5 1.0 CD A:GLN86 4.9 41.7 1.0

Calcium binding site 2 out of 3 in the Human H Ferritin with 2 Fe(II)/Subunit Loading


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human H Ferritin with 2 Fe(II)/Subunit Loading within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca205 b:72.2 occ:0.33 O A:HOH306 2.3 60.1 0.3 OD1 A:ASP131 2.5 51.4 1.0 O A:HOH323 2.7 53.5 1.0 OE1 A:GLU134 3.0 55.7 1.0 CG A:ASP131 3.8 54.4 1.0 CD A:GLU134 4.2 49.5 1.0 O A:HOH356 4.5 50.2 1.0 OD2 A:ASP131 4.6 46.7 1.0 CB A:ASP131 4.7 42.0 1.0 CB A:GLU134 4.8 42.5 1.0 CA A:ASP131 5.0 35.4 1.0 OE2 A:GLU134 5.0 52.4 1.0

Calcium binding site 3 out of 3 in the Human H Ferritin with 2 Fe(II)/Subunit Loading


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human H Ferritin with 2 Fe(II)/Subunit Loading within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca206 b:54.6 occ:0.25 NE2 A:HIS173 3.0 38.3 1.0 CE1 A:HIS173 3.7 37.1 1.0 CD2 A:LEU169 3.9 28.6 1.0 CD2 A:HIS173 4.0 35.7 1.0 ND1 A:HIS173 4.8 39.7 1.0

T.Zhang, R.Jiao. Human H Ferritin with 2 Fe(II)/Subunit Loading To Be Published.