Calcium in PDB 8wpl: Cryo-Em Structure of the Human TRPC1/C4 Heteromer

The structure of Cryo-Em Structure of the Human TRPC1/C4 Heteromer also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Calcium atom in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer (pdb code 8wpl). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer, PDB code: 8wpl:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1004 b:89.1 occ:1.00 OE2 B:GLU417 2.4 104.3 1.0 OD1 B:ASN435 3.0 94.5 1.0 OE1 B:GLU417 3.0 107.0 1.0 CD B:GLU417 3.1 105.3 1.0 OE1 B:GLN420 3.3 118.1 1.0 OD2 B:ASP438 3.5 90.1 1.0 CG B:ASP438 3.8 87.2 1.0 CG B:ASN435 3.9 95.2 1.0 CB B:ASP438 3.9 79.5 1.0 CA B:ASN435 4.1 91.2 1.0 CD B:GLN420 4.2 117.6 1.0 CB B:ASN435 4.4 94.8 1.0 OD1 B:ASP438 4.4 82.4 1.0 CG B:GLU417 4.6 103.2 1.0 NE2 B:GLN420 4.6 117.8 1.0 O B:TRP434 4.7 86.5 1.0 N B:ASN435 4.7 91.1 1.0 ND2 B:ASN435 4.8 92.8 1.0 CE2 B:TYR429 4.9 107.5 1.0 NH2 B:ARG491 5.0 64.5 1.0 O B:ASN435 5.0 97.0 1.0 NH1 B:ARG491 5.0 64.4 1.0

Calcium binding site 2 out of 3 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1004 b:82.5 occ:1.00 OE2 C:GLU417 2.6 96.7 1.0 OD1 C:ASP438 2.9 70.6 1.0 OE1 C:GLN420 2.9 108.7 1.0 OE1 C:GLU417 3.2 93.7 1.0 CD C:GLU417 3.2 96.3 1.0 OD1 C:ASN435 3.4 79.4 1.0 CG C:ASP438 3.7 72.5 1.0 CG C:ASN435 3.7 79.1 1.0 OD2 C:ASP438 3.7 77.5 1.0 CD C:GLN420 3.9 107.7 1.0 ND2 C:ASN435 3.9 82.4 1.0 NE2 C:GLN420 4.1 106.3 1.0 CA C:ASN435 4.5 74.9 1.0 CB C:ASN435 4.6 76.7 1.0 CG C:GLU417 4.7 94.6 1.0 NH1 C:ARG491 5.0 46.7 1.0 CB C:ASP438 5.0 71.0 1.0

Calcium binding site 3 out of 3 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1003 b:82.0 occ:1.00 OE2 D:GLU417 2.4 88.7 1.0 OD1 D:ASN435 2.5 83.1 1.0 OE1 D:GLN420 2.7 101.7 1.0 OE1 D:GLU417 2.9 95.1 1.0 CD D:GLU417 3.0 91.1 1.0 CD D:GLN420 3.5 102.7 1.0 CG D:ASN435 3.7 83.5 1.0 NE2 D:GLN420 3.7 103.9 1.0 NH1 D:ARG491 3.8 54.7 1.0 OD2 D:ASP438 3.9 72.0 1.0 CB D:ASP438 4.2 64.1 1.0 CG D:ASP438 4.3 71.4 1.0 CA D:ASN435 4.4 80.0 1.0 CG D:GLU417 4.5 89.8 1.0 ND2 D:ASN435 4.6 82.4 1.0 CB D:ASN435 4.6 81.7 1.0 CE1 D:TYR429 4.8 100.9 1.0 CG D:GLN420 4.9 102.8 1.0 CZ D:ARG491 4.9 49.7 1.0

J.Won, H.Jeong, H.H.Lee. Structure of A Trp Channel To Be Published.