Calcium in PDB 9asm: Human Drosha and DGCR8 in Complex with Pri-Let-7F1

All present enzymatic activity of Human Drosha and DGCR8 in Complex with Pri-Let-7F1:
3.1.26.3;

The structure of Human Drosha and DGCR8 in Complex with Pri-Let-7F1 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Calcium atom in the Human Drosha and DGCR8 in Complex with Pri-Let-7F1 (pdb code 9asm). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Drosha and DGCR8 in Complex with Pri-Let-7F1, PDB code: 9asm:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Drosha and DGCR8 in Complex with Pri-Let-7F1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Drosha and DGCR8 in Complex with Pri-Let-7F1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1403 b:30.0 occ:1.00 OE2 A:GLU1147 2.4 141.8 1.0 OP1 E:U31 2.6 159.9 1.0 OE1 A:GLU1222 3.0 141.2 1.0 OD1 A:ASP1219 3.2 148.2 1.0 CD A:GLU1147 3.5 141.8 1.0 OE2 A:GLU1222 3.5 141.2 1.0 CD A:GLU1222 3.6 141.2 1.0 CG A:GLU1147 3.8 141.8 1.0 P E:U31 4.0 159.9 1.0 O A:HOH1501 4.2 30.0 1.0 C5' E:U31 4.3 159.9 1.0 O5' E:U31 4.3 159.9 1.0 CG A:ASP1219 4.3 148.2 1.0 OD2 A:ASP1151 4.4 136.2 1.0 OE1 A:GLU1147 4.5 141.8 1.0 CG A:ASP1151 4.8 136.2 1.0 OP2 E:U31 4.9 159.9 1.0 OD2 A:ASP1219 5.0 148.2 1.0

Calcium binding site 2 out of 2 in the Human Drosha and DGCR8 in Complex with Pri-Let-7F1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Drosha and DGCR8 in Complex with Pri-Let-7F1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1404 b:30.0 occ:1.00 OD1 A:ASN1042 2.7 127.5 1.0 OE1 A:GLU1045 2.9 124.2 1.0 OE2 A:GLU969 3.2 30.0 1.0 OE2 A:GLU1045 3.5 124.2 1.0 CD A:GLU1045 3.5 124.2 1.0 CG A:ASN1042 3.8 127.5 1.0 CD A:GLU969 3.9 30.0 1.0 OD1 A:ASN1006 4.2 129.7 1.0 CG A:GLU969 4.2 30.0 1.0 ND2 A:ASN1042 4.6 127.5 1.0 CA A:ASN1042 4.8 127.5 1.0 CB A:ASN1042 4.8 127.5 1.0 OE1 A:GLU969 4.9 30.0 1.0 ND2 A:ASN1006 4.9 129.7 1.0 CG A:GLU1045 4.9 124.2 1.0 CG A:ASN1006 5.0 129.7 1.0

A.Garg, L.Joshua-Tor. RNAI_PROTEIN_F1 To Be Published.