Calcium in PDB 9o7s: Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
Other elements in 9o7s:
The structure of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
(pdb code 9o7s). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309, PDB code: 9o7s:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 1 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca202
b:123.3
occ:1.00
|
OE1
|
E:GLU31
|
2.3
|
111.5
|
1.0
|
|
OD1
|
E:ASP20
|
2.3
|
109.4
|
1.0
|
|
OD1
|
E:ASP22
|
2.3
|
120.6
|
1.0
|
|
OD2
|
E:ASP22
|
2.4
|
120.8
|
1.0
|
|
O
|
E:THR26
|
2.4
|
111.5
|
1.0
|
|
OE2
|
E:GLU31
|
2.4
|
109.6
|
1.0
|
|
CD
|
E:GLU31
|
2.6
|
110.5
|
1.0
|
|
CG
|
E:ASP22
|
2.7
|
119.4
|
1.0
|
|
C
|
E:THR26
|
3.6
|
112.5
|
1.0
|
|
CG
|
E:ASP20
|
3.6
|
107.4
|
1.0
|
|
CB
|
E:ASP24
|
4.1
|
118.6
|
1.0
|
|
OD2
|
E:ASP24
|
4.1
|
123.5
|
1.0
|
|
CG
|
E:ASP24
|
4.1
|
122.3
|
1.0
|
|
CG
|
E:GLU31
|
4.1
|
106.0
|
1.0
|
|
CB
|
E:ASP22
|
4.2
|
115.3
|
1.0
|
|
CA
|
E:ILE27
|
4.3
|
107.6
|
1.0
|
|
CG2
|
E:THR28
|
4.3
|
109.8
|
1.0
|
|
CA
|
E:ASP20
|
4.3
|
100.5
|
1.0
|
|
N
|
E:ASP24
|
4.4
|
114.5
|
1.0
|
|
N
|
E:ILE27
|
4.4
|
111.7
|
1.0
|
|
N
|
E:THR28
|
4.4
|
109.3
|
1.0
|
|
OD2
|
E:ASP20
|
4.4
|
109.5
|
1.0
|
|
CB
|
E:ASP20
|
4.5
|
100.4
|
1.0
|
|
N
|
E:THR26
|
4.5
|
109.3
|
1.0
|
|
N
|
E:ASP22
|
4.5
|
115.5
|
1.0
|
|
CG2
|
E:THR26
|
4.6
|
108.9
|
1.0
|
|
CA
|
E:THR26
|
4.6
|
111.9
|
1.0
|
|
OD1
|
E:ASP24
|
4.7
|
121.2
|
1.0
|
|
N
|
E:GLY23
|
4.7
|
115.3
|
1.0
|
|
C
|
E:ASP20
|
4.8
|
108.7
|
1.0
|
|
CA
|
E:ASP24
|
4.8
|
117.2
|
1.0
|
|
OG1
|
E:THR28
|
4.8
|
104.0
|
1.0
|
|
C
|
E:ILE27
|
4.8
|
109.7
|
1.0
|
|
N
|
E:LYS21
|
4.8
|
109.1
|
1.0
|
|
CA
|
E:ASP22
|
4.9
|
115.2
|
1.0
|
|
Calcium binding site 2 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 2 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca203
b:137.2
occ:1.00
|
OD1
|
E:ASP56
|
2.2
|
128.4
|
1.0
|
|
ND2
|
E:ASN60
|
2.2
|
127.0
|
1.0
|
|
OD1
|
E:ASP58
|
2.3
|
133.1
|
1.0
|
|
OD2
|
E:ASP58
|
2.3
|
131.9
|
1.0
|
|
OD1
|
E:ASN60
|
2.4
|
132.1
|
1.0
|
|
OD2
|
E:ASP64
|
2.4
|
129.4
|
1.0
|
|
OE2
|
E:GLU67
|
2.4
|
128.4
|
1.0
|
|
O
|
E:THR62
|
2.4
|
124.5
|
1.0
|
|
OE1
|
E:GLU67
|
2.4
|
124.1
|
1.0
|
|
OD1
|
E:ASP64
|
2.4
|
123.7
|
1.0
|
|
CG
|
E:ASP64
|
2.5
|
123.9
|
1.0
|
|
OD2
|
E:ASP56
|
2.6
|
127.9
|
1.0
|
|
CG
|
E:ASN60
|
2.6
|
129.4
|
1.0
|
|
CG
|
E:ASP58
|
2.6
|
131.3
|
1.0
|
|
CG
|
E:ASP56
|
2.7
|
126.7
|
1.0
|
|
CD
|
E:GLU67
|
2.7
|
124.4
|
1.0
|
|
C
|
E:THR62
|
3.6
|
122.5
|
1.0
|
|
N
|
E:ASP64
|
3.7
|
112.2
|
1.0
|
|
CB
|
E:ASP64
|
3.7
|
115.0
|
1.0
|
|
CB
|
E:ASN60
|
4.0
|
126.7
|
1.0
|
|
CB
|
E:ASP58
|
4.1
|
130.2
|
1.0
|
|
C
|
E:ILE63
|
4.1
|
111.6
|
1.0
|
|
CB
|
E:ASP56
|
4.2
|
124.9
|
1.0
|
|
CA
|
E:ILE63
|
4.2
|
114.3
|
1.0
|
|
CG
|
E:GLU67
|
4.2
|
115.5
|
1.0
|
|
CA
|
E:ASP64
|
4.3
|
110.2
|
1.0
|
|
N
|
E:ILE63
|
4.4
|
117.2
|
1.0
|
|
N
|
E:ASN60
|
4.5
|
131.2
|
1.0
|
|
N
|
E:THR62
|
4.6
|
128.0
|
1.0
|
|
CA
|
E:ASP56
|
4.7
|
126.2
|
1.0
|
|
CA
|
E:THR62
|
4.7
|
124.8
|
1.0
|
|
N
|
E:ASP58
|
4.7
|
132.3
|
1.0
|
|
OG1
|
E:THR62
|
4.8
|
122.2
|
1.0
|
|
CA
|
E:ASN60
|
4.8
|
128.6
|
1.0
|
|
CA
|
E:ASP58
|
4.9
|
132.2
|
1.0
|
|
Calcium binding site 3 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 3 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca202
b:124.8
occ:1.00
|
OE2
|
F:GLU31
|
2.2
|
114.6
|
1.0
|
|
OD1
|
F:ASP20
|
2.3
|
108.8
|
1.0
|
|
OD2
|
F:ASP24
|
2.3
|
120.6
|
1.0
|
|
OD1
|
F:ASP24
|
2.3
|
120.5
|
1.0
|
|
O
|
F:THR26
|
2.4
|
111.5
|
1.0
|
|
OD1
|
F:ASP22
|
2.4
|
119.5
|
1.0
|
|
OE1
|
F:GLU31
|
2.4
|
111.7
|
1.0
|
|
CD
|
F:GLU31
|
2.6
|
112.0
|
1.0
|
|
CG
|
F:ASP24
|
2.6
|
120.2
|
1.0
|
|
CG
|
F:ASP22
|
3.5
|
118.1
|
1.0
|
|
CG
|
F:ASP20
|
3.5
|
106.3
|
1.0
|
|
C
|
F:THR26
|
3.6
|
112.6
|
1.0
|
|
OD2
|
F:ASP22
|
3.8
|
117.1
|
1.0
|
|
O
|
F:ASP22
|
3.9
|
116.2
|
1.0
|
|
CG
|
F:GLU31
|
4.1
|
107.0
|
1.0
|
|
CB
|
F:ASP24
|
4.1
|
117.4
|
1.0
|
|
CA
|
F:ILE27
|
4.2
|
108.0
|
1.0
|
|
CA
|
F:ASP20
|
4.2
|
99.4
|
1.0
|
|
OD2
|
F:ASP20
|
4.3
|
109.6
|
1.0
|
|
N
|
F:ILE27
|
4.3
|
111.7
|
1.0
|
|
N
|
F:THR28
|
4.4
|
108.8
|
1.0
|
|
CG2
|
F:THR28
|
4.4
|
109.3
|
1.0
|
|
CB
|
F:ASP20
|
4.5
|
98.2
|
1.0
|
|
N
|
F:THR26
|
4.5
|
110.0
|
1.0
|
|
N
|
F:ASP22
|
4.6
|
114.2
|
1.0
|
|
N
|
F:LYS21
|
4.6
|
107.8
|
1.0
|
|
CA
|
F:THR26
|
4.7
|
111.9
|
1.0
|
|
C
|
F:ASP22
|
4.7
|
116.1
|
1.0
|
|
C
|
F:ASP20
|
4.7
|
106.8
|
1.0
|
|
CB
|
F:ASP22
|
4.8
|
115.2
|
1.0
|
|
N
|
F:ASP24
|
4.8
|
117.0
|
1.0
|
|
C
|
F:ILE27
|
4.8
|
110.3
|
1.0
|
|
OG1
|
F:THR28
|
4.8
|
103.7
|
1.0
|
|
CG2
|
F:THR26
|
4.8
|
110.0
|
1.0
|
|
CA
|
F:ASP22
|
4.9
|
114.3
|
1.0
|
|
CA
|
F:ASP24
|
5.0
|
118.3
|
1.0
|
|
CB
|
F:GLU31
|
5.0
|
99.1
|
1.0
|
|
Calcium binding site 4 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 4 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca203
b:131.9
occ:1.00
|
ND2
|
F:ASN60
|
2.3
|
123.8
|
1.0
|
|
OD1
|
F:ASP56
|
2.3
|
124.7
|
1.0
|
|
OD1
|
F:ASP58
|
2.3
|
131.9
|
1.0
|
|
OD1
|
F:ASN60
|
2.3
|
126.8
|
1.0
|
|
OE2
|
F:GLU67
|
2.4
|
127.3
|
1.0
|
|
CG
|
F:ASN60
|
2.4
|
125.3
|
1.0
|
|
OD2
|
F:ASP64
|
2.4
|
126.6
|
1.0
|
|
OE1
|
F:GLU67
|
2.5
|
122.7
|
1.0
|
|
OD1
|
F:ASP64
|
2.5
|
122.2
|
1.0
|
|
O
|
F:THR62
|
2.5
|
121.6
|
1.0
|
|
CG
|
F:ASP64
|
2.6
|
121.6
|
1.0
|
|
O
|
F:ASP58
|
2.7
|
130.1
|
1.0
|
|
CD
|
F:GLU67
|
2.7
|
123.3
|
1.0
|
|
CG
|
F:ASP56
|
3.3
|
122.2
|
1.0
|
|
CG
|
F:ASP58
|
3.4
|
131.2
|
1.0
|
|
OD2
|
F:ASP56
|
3.7
|
120.4
|
1.0
|
|
CB
|
F:ASN60
|
3.7
|
123.4
|
1.0
|
|
C
|
F:THR62
|
3.8
|
120.8
|
1.0
|
|
N
|
F:ASP64
|
3.9
|
112.9
|
1.0
|
|
C
|
F:ASP58
|
3.9
|
128.7
|
1.0
|
|
CB
|
F:ASP64
|
3.9
|
113.4
|
1.0
|
|
OD2
|
F:ASP58
|
4.0
|
132.4
|
1.0
|
|
N
|
F:ASN60
|
4.1
|
126.7
|
1.0
|
|
CG
|
F:GLU67
|
4.2
|
113.6
|
1.0
|
|
N
|
F:ASP58
|
4.4
|
130.9
|
1.0
|
|
C
|
F:ILE63
|
4.4
|
111.5
|
1.0
|
|
CA
|
F:ILE63
|
4.4
|
114.0
|
1.0
|
|
CA
|
F:ASP64
|
4.4
|
110.9
|
1.0
|
|
CB
|
F:ASP56
|
4.5
|
123.2
|
1.0
|
|
CA
|
F:ASN60
|
4.5
|
124.7
|
1.0
|
|
CA
|
F:ASP58
|
4.5
|
129.8
|
1.0
|
|
N
|
F:ILE63
|
4.5
|
116.5
|
1.0
|
|
CB
|
F:ASP58
|
4.6
|
130.2
|
1.0
|
|
CA
|
F:ASP56
|
4.6
|
124.8
|
1.0
|
|
N
|
F:THR62
|
4.6
|
124.7
|
1.0
|
|
CA
|
F:THR62
|
4.8
|
121.6
|
1.0
|
|
N
|
F:ALA57
|
4.9
|
128.7
|
1.0
|
|
C
|
F:ASP56
|
4.9
|
126.4
|
1.0
|
|
OG1
|
F:THR62
|
4.9
|
117.8
|
1.0
|
|
N
|
F:GLY59
|
5.0
|
125.3
|
1.0
|
|
Calcium binding site 5 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 5 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca202
b:130.9
occ:1.00
|
OE2
|
G:GLU31
|
2.3
|
117.4
|
1.0
|
|
OD1
|
G:ASP22
|
2.3
|
124.1
|
1.0
|
|
O
|
G:THR26
|
2.3
|
113.2
|
1.0
|
|
OD1
|
G:ASP20
|
2.4
|
113.5
|
1.0
|
|
OD1
|
G:ASP24
|
2.4
|
124.5
|
1.0
|
|
OD2
|
G:ASP24
|
2.4
|
123.5
|
1.0
|
|
OD2
|
G:ASP22
|
2.4
|
125.8
|
1.0
|
|
OE1
|
G:GLU31
|
2.4
|
112.4
|
1.0
|
|
CG
|
G:ASP22
|
2.7
|
123.7
|
1.0
|
|
CD
|
G:GLU31
|
2.7
|
114.2
|
1.0
|
|
CG
|
G:ASP24
|
2.7
|
122.8
|
1.0
|
|
CG
|
G:ASP20
|
3.6
|
109.5
|
1.0
|
|
C
|
G:THR26
|
3.6
|
113.8
|
1.0
|
|
CG2
|
G:THR28
|
4.0
|
111.5
|
1.0
|
|
OD2
|
G:ASP20
|
4.2
|
110.7
|
1.0
|
|
CB
|
G:ASP22
|
4.2
|
118.6
|
1.0
|
|
CG
|
G:GLU31
|
4.2
|
109.4
|
1.0
|
|
CB
|
G:ASP24
|
4.2
|
119.1
|
1.0
|
|
OG1
|
G:THR26
|
4.2
|
113.3
|
1.0
|
|
N
|
G:THR28
|
4.4
|
109.4
|
1.0
|
|
CA
|
G:ILE27
|
4.4
|
108.4
|
1.0
|
|
N
|
G:ILE27
|
4.4
|
112.2
|
1.0
|
|
N
|
G:THR26
|
4.4
|
111.6
|
1.0
|
|
CA
|
G:THR26
|
4.5
|
114.5
|
1.0
|
|
CB
|
G:ASP20
|
4.7
|
102.1
|
1.0
|
|
CA
|
G:ASP20
|
4.7
|
101.7
|
1.0
|
|
OG1
|
G:THR28
|
4.8
|
104.7
|
1.0
|
|
C
|
G:ILE27
|
4.8
|
110.9
|
1.0
|
|
N
|
G:ASP22
|
4.9
|
119.0
|
1.0
|
|
CB
|
G:THR28
|
5.0
|
108.3
|
1.0
|
|
CA
|
G:ASP22
|
5.0
|
118.2
|
1.0
|
|
O
|
G:ASP22
|
5.0
|
119.0
|
1.0
|
|
N
|
G:ASP24
|
5.0
|
120.2
|
1.0
|
|
CA
|
G:ASP24
|
5.0
|
120.9
|
1.0
|
|
Calcium binding site 6 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 6 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca203
b:127.4
occ:1.00
|
OD1
|
G:ASP56
|
2.3
|
122.3
|
1.0
|
|
OE2
|
G:GLU67
|
2.4
|
126.1
|
1.0
|
|
OE1
|
G:GLU67
|
2.5
|
121.5
|
1.0
|
|
O
|
G:THR62
|
2.5
|
122.0
|
1.0
|
|
OD1
|
G:ASP58
|
2.5
|
133.7
|
1.0
|
|
OD1
|
G:ASP64
|
2.5
|
120.3
|
1.0
|
|
CD
|
G:GLU67
|
2.8
|
121.3
|
1.0
|
|
O
|
G:ALA57
|
2.8
|
135.5
|
1.0
|
|
CG
|
G:ASP64
|
2.9
|
120.9
|
1.0
|
|
OD2
|
G:ASP64
|
3.0
|
127.0
|
1.0
|
|
O
|
G:GLY59
|
3.1
|
132.4
|
1.0
|
|
CG
|
G:ASP56
|
3.5
|
122.0
|
1.0
|
|
CG
|
G:ASP58
|
3.5
|
133.3
|
1.0
|
|
C
|
G:THR62
|
3.7
|
121.2
|
1.0
|
|
OD2
|
G:ASP58
|
3.8
|
133.1
|
1.0
|
|
N
|
G:ASP64
|
3.9
|
111.6
|
1.0
|
|
C
|
G:ALA57
|
4.1
|
133.2
|
1.0
|
|
OD2
|
G:ASP56
|
4.1
|
120.5
|
1.0
|
|
CB
|
G:ASP64
|
4.2
|
112.4
|
1.0
|
|
CB
|
G:ASN60
|
4.2
|
126.9
|
1.0
|
|
C
|
G:GLY59
|
4.3
|
130.3
|
1.0
|
|
CG
|
G:GLU67
|
4.3
|
113.6
|
1.0
|
|
CA
|
G:ILE63
|
4.3
|
113.3
|
1.0
|
|
C
|
G:ILE63
|
4.4
|
110.4
|
1.0
|
|
N
|
G:ILE63
|
4.5
|
116.0
|
1.0
|
|
N
|
G:ALA57
|
4.5
|
128.0
|
1.0
|
|
CA
|
G:ASP64
|
4.6
|
110.2
|
1.0
|
|
CA
|
G:ASP56
|
4.6
|
123.9
|
1.0
|
|
ND2
|
G:ASN60
|
4.6
|
130.8
|
1.0
|
|
CB
|
G:ASP56
|
4.7
|
123.5
|
1.0
|
|
N
|
G:THR62
|
4.7
|
125.5
|
1.0
|
|
CG
|
G:ASN60
|
4.7
|
131.4
|
1.0
|
|
C
|
G:ASP56
|
4.7
|
126.3
|
1.0
|
|
CA
|
G:THR62
|
4.8
|
122.5
|
1.0
|
|
C
|
G:ASP58
|
4.8
|
133.5
|
1.0
|
|
N
|
G:GLY59
|
4.9
|
130.0
|
1.0
|
|
CB
|
G:ASP58
|
4.9
|
134.6
|
1.0
|
|
OG1
|
G:THR62
|
4.9
|
119.6
|
1.0
|
|
CA
|
G:ALA57
|
4.9
|
128.9
|
1.0
|
|
Calcium binding site 7 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 7 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Ca202
b:120.8
occ:1.00
|
O
|
H:THR26
|
2.2
|
111.5
|
1.0
|
|
N
|
H:THR28
|
2.3
|
111.8
|
1.0
|
|
OD2
|
H:ASP24
|
2.3
|
116.5
|
1.0
|
|
OE2
|
H:GLU31
|
2.4
|
113.3
|
1.0
|
|
OE1
|
H:GLU31
|
2.4
|
108.9
|
1.0
|
|
OD1
|
H:ASP20
|
2.5
|
108.7
|
1.0
|
|
OD1
|
H:ASP22
|
2.6
|
118.6
|
1.0
|
|
CD
|
H:GLU31
|
2.6
|
109.4
|
1.0
|
|
OD1
|
H:ASP24
|
2.6
|
116.7
|
1.0
|
|
CG
|
H:ASP24
|
2.8
|
117.7
|
1.0
|
|
C
|
H:ILE27
|
3.0
|
110.4
|
1.0
|
|
CA
|
H:ILE27
|
3.0
|
107.6
|
1.0
|
|
C
|
H:THR26
|
3.2
|
110.9
|
1.0
|
|
CA
|
H:THR28
|
3.3
|
109.3
|
1.0
|
|
CB
|
H:THR28
|
3.4
|
108.0
|
1.0
|
|
CG
|
H:ASP22
|
3.5
|
119.2
|
1.0
|
|
N
|
H:ILE27
|
3.6
|
109.7
|
1.0
|
|
OD2
|
H:ASP22
|
3.6
|
119.2
|
1.0
|
|
CG2
|
H:THR28
|
3.7
|
106.1
|
1.0
|
|
CG
|
H:ASP20
|
3.7
|
106.7
|
1.0
|
|
CG
|
H:GLU31
|
4.0
|
105.2
|
1.0
|
|
O
|
H:ILE27
|
4.2
|
109.5
|
1.0
|
|
CB
|
H:ASP24
|
4.4
|
118.2
|
1.0
|
|
CB
|
H:ILE27
|
4.4
|
101.6
|
1.0
|
|
OD2
|
H:ASP20
|
4.5
|
107.8
|
1.0
|
|
O
|
H:ASP22
|
4.5
|
116.3
|
1.0
|
|
C
|
H:THR28
|
4.5
|
106.0
|
1.0
|
|
CA
|
H:THR26
|
4.6
|
111.5
|
1.0
|
|
CB
|
H:GLU31
|
4.6
|
99.7
|
1.0
|
|
CA
|
H:ASP20
|
4.7
|
99.5
|
1.0
|
|
O
|
H:THR28
|
4.7
|
105.9
|
1.0
|
|
CG2
|
H:ILE27
|
4.7
|
102.7
|
1.0
|
|
OG1
|
H:THR28
|
4.7
|
108.7
|
1.0
|
|
CB
|
H:ASP20
|
4.7
|
99.0
|
1.0
|
|
N
|
H:THR26
|
4.8
|
111.0
|
1.0
|
|
CG2
|
H:THR26
|
4.9
|
108.3
|
1.0
|
|
CB
|
H:ASP22
|
4.9
|
114.2
|
1.0
|
|
Calcium binding site 8 out
of 8 in 9o7s
Go back to
Calcium Binding Sites List in 9o7s
Calcium binding site 8 out
of 8 in the Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Cryo-Em Structure of KCA2.2/Calmodulin Channel in Complex with NS309 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Ca203
b:129.3
occ:1.00
|
OD1
|
H:ASP56
|
2.3
|
127.7
|
1.0
|
|
OD2
|
H:ASP58
|
2.4
|
129.1
|
1.0
|
|
OE1
|
H:GLU67
|
2.4
|
120.4
|
1.0
|
|
O
|
H:THR62
|
2.4
|
121.2
|
1.0
|
|
OD2
|
H:ASP56
|
2.4
|
121.1
|
1.0
|
|
OE2
|
H:GLU67
|
2.4
|
123.2
|
1.0
|
|
OD1
|
H:ASP58
|
2.5
|
129.8
|
1.0
|
|
OD1
|
H:ASP64
|
2.5
|
117.6
|
1.0
|
|
CG
|
H:ASP56
|
2.6
|
123.2
|
1.0
|
|
CG
|
H:ASP58
|
2.8
|
128.5
|
1.0
|
|
CD
|
H:GLU67
|
2.8
|
120.0
|
1.0
|
|
CG
|
H:ASP64
|
2.9
|
117.1
|
1.0
|
|
OD2
|
H:ASP64
|
3.0
|
121.6
|
1.0
|
|
C
|
H:THR62
|
3.6
|
119.7
|
1.0
|
|
N
|
H:ASP64
|
3.7
|
109.4
|
1.0
|
|
CB
|
H:ASP64
|
4.0
|
110.1
|
1.0
|
|
CB
|
H:ASP56
|
4.0
|
121.0
|
1.0
|
|
ND2
|
H:ASN60
|
4.1
|
125.5
|
1.0
|
|
C
|
H:ILE63
|
4.2
|
109.0
|
1.0
|
|
CA
|
H:ILE63
|
4.2
|
110.7
|
1.0
|
|
CB
|
H:ASP58
|
4.3
|
126.8
|
1.0
|
|
CG
|
H:GLU67
|
4.3
|
111.6
|
1.0
|
|
CB
|
H:ASN60
|
4.3
|
125.8
|
1.0
|
|
N
|
H:ILE63
|
4.4
|
113.1
|
1.0
|
|
CA
|
H:ASP64
|
4.4
|
107.3
|
1.0
|
|
CG
|
H:ASN60
|
4.5
|
128.5
|
1.0
|
|
OG1
|
H:THR62
|
4.5
|
120.9
|
1.0
|
|
CA
|
H:ASP56
|
4.7
|
124.1
|
1.0
|
|
N
|
H:THR62
|
4.7
|
126.0
|
1.0
|
|
CA
|
H:THR62
|
4.7
|
122.3
|
1.0
|
|
N
|
H:ASP58
|
4.8
|
129.4
|
1.0
|
|
OG1
|
H:THR26
|
4.9
|
114.9
|
1.0
|
|
N
|
H:ASN60
|
4.9
|
128.1
|
1.0
|
|
Reference:
M.Zhang,
Y.W.Nam,
A.Ramanishka,
Y.Xu,
R.M.Yasuda,
D.Im,
M.Cui,
G.Chandy,
H.Wulff.
Structural Basis For the Subtype-Selectivity of KCA2.2 Channel Activators. Res Sq 2025.
ISSN: ESSN 2693-5015
PubMed: 40470184
DOI: 10.21203/RS.3.RS-6568445/V1
Page generated: Thu Jul 10 10:22:58 2025
|
