Calcium in PDB 1aei: Crystal Structure of the Annexin XII Hexamer

The structure of Crystal Structure of the Annexin XII Hexamer, PDB code: 1aei was solved by H.Luecke, B.T.Chang, W.S.Mailliard, D.D.Schlaepfer, H.T.Haigler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	71.200, 179.200, 100.700, 90.00, 97.60, 90.00
R / Rfree (%)	23.6 / 27.8

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 24;

Binding sites:

The binding sites of Calcium atom in the Crystal Structure of the Annexin XII Hexamer (pdb code 1aei). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 24 binding sites of Calcium where determined in the Crystal Structure of the Annexin XII Hexamer, PDB code: 1aei:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca1 b:9.3 occ:1.00 OE2 A:GLU105 2.2 29.6 1.0 O E:LEU71 2.2 2.6 1.0 OE2 E:GLU76 2.2 2.0 1.0 O E:LYS68 2.3 7.5 1.0 CD A:GLU105 3.3 27.4 1.0 CD E:GLU76 3.4 2.0 1.0 C E:LEU71 3.4 2.0 1.0 C E:LYS68 3.5 2.0 1.0 OE1 E:GLU76 3.9 2.0 1.0 CG A:GLU105 3.9 19.7 1.0 CA E:SER72 4.1 4.9 1.0 OG E:SER72 4.2 21.0 1.0 N E:SER72 4.2 2.2 1.0 OD2 A:ASP230 4.2 11.7 1.0 OE1 A:GLU105 4.2 28.4 1.0 CA E:LYS68 4.3 4.2 1.0 H E:LEU71 4.3 0.0 1.0 HG E:SER72 4.5 0.0 1.0 N E:SER69 4.5 2.0 1.0 CG E:GLU76 4.6 2.0 1.0 N E:LEU71 4.6 2.0 1.0 CA E:LEU71 4.6 2.0 1.0 O E:SER69 4.6 9.5 1.0 CA E:SER69 4.7 4.2 1.0 CB E:SER72 4.8 8.2 1.0 C E:SER69 4.8 7.8 1.0 CB E:LYS68 4.8 5.0 1.0 H E:GLY73 4.9 0.0 1.0

Calcium binding site 2 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca317 b:3.0 occ:1.00 OE2 D:GLU76 2.1 2.0 1.0 OE2 B:GLU105 2.1 34.2 1.0 O D:LYS68 2.2 7.1 1.0 O D:LEU71 2.3 6.2 1.0 CD B:GLU105 3.2 32.2 1.0 CD D:GLU76 3.2 4.1 1.0 C D:LYS68 3.4 3.8 1.0 C D:LEU71 3.6 4.7 1.0 OE1 D:GLU76 3.7 5.5 1.0 CG B:GLU105 3.8 22.1 1.0 OD2 B:ASP230 4.1 15.1 1.0 OE1 B:GLU105 4.1 33.8 1.0 CA D:LYS68 4.1 2.0 1.0 CA D:SER72 4.2 8.1 1.0 OG D:SER72 4.3 21.5 1.0 N D:SER72 4.3 4.7 1.0 HG D:SER72 4.4 0.0 1.0 CG D:GLU76 4.4 2.0 1.0 H D:LEU71 4.5 0.0 1.0 N D:SER69 4.5 2.4 1.0 O D:SER69 4.6 6.0 1.0 CB D:LYS68 4.6 2.0 1.0 CA D:SER69 4.6 2.7 1.0 CA D:LEU71 4.7 4.1 1.0 N D:LEU71 4.7 4.6 1.0 C D:SER69 4.8 3.8 1.0 CB D:SER72 4.9 11.1 1.0 H B:THR103 4.9 0.0 1.0 CB B:THR103 4.9 5.4 1.0 H D:GLY73 5.0 0.0 1.0

Calcium binding site 3 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca317 b:3.9 occ:1.00 OE2 C:GLU105 2.0 30.5 1.0 OE2 F:GLU76 2.1 2.0 1.0 O F:LYS68 2.2 2.7 1.0 O F:LEU71 2.3 2.0 1.0 CD C:GLU105 3.1 33.4 1.0 CD F:GLU76 3.2 2.0 1.0 C F:LYS68 3.4 2.0 1.0 C F:LEU71 3.5 2.0 1.0 CG C:GLU105 3.7 29.4 1.0 OE1 F:GLU76 3.8 2.0 1.0 OD2 C:ASP230 4.0 25.3 1.0 CA F:LYS68 4.0 2.0 1.0 OE1 C:GLU105 4.1 37.5 1.0 CA F:SER72 4.2 2.9 1.0 N F:SER72 4.2 2.0 1.0 OG F:SER72 4.3 13.2 1.0 CG F:GLU76 4.3 2.0 1.0 HG F:SER72 4.4 0.0 1.0 H F:LEU71 4.4 0.0 1.0 N F:SER69 4.5 2.0 1.0 CB F:LYS68 4.6 2.0 1.0 CA F:LEU71 4.6 2.0 1.0 HG1 C:THR103 4.7 0.0 1.0 N F:LEU71 4.7 4.5 1.0 CA F:SER69 4.8 3.8 1.0 CB C:THR103 4.8 2.2 1.0 O F:LEU67 4.8 2.0 1.0 O F:SER69 4.9 8.8 1.0 OG1 C:THR103 4.9 2.0 1.0 OD1 C:ASP230 4.9 22.0 1.0 CG C:ASP230 4.9 19.9 1.0 CB F:SER72 4.9 2.2 1.0 C F:SER69 4.9 5.8 1.0 CB F:GLU76 5.0 2.0 1.0 H F:GLY73 5.0 0.0 1.0

Calcium binding site 4 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca317 b:2.0 occ:1.00 OE2 B:GLU76 2.1 2.0 1.0 OE2 D:GLU105 2.1 33.4 1.0 O B:LYS68 2.3 7.2 1.0 O B:LEU71 2.4 7.8 1.0 CD D:GLU105 3.2 30.5 1.0 CD B:GLU76 3.3 2.7 1.0 C B:LYS68 3.5 3.0 1.0 C B:LEU71 3.6 6.1 1.0 OE1 B:GLU76 3.7 3.7 1.0 CG D:GLU105 3.8 24.1 1.0 HG B:SER72 4.2 0.0 1.0 OE1 D:GLU105 4.2 27.8 1.0 OD2 D:ASP230 4.2 17.2 1.0 OG B:SER72 4.2 24.3 1.0 CA B:SER72 4.2 6.1 1.0 CA B:LYS68 4.2 3.3 1.0 N B:SER72 4.3 4.8 1.0 H B:LEU71 4.4 0.0 1.0 N B:SER69 4.5 4.0 1.0 CG B:GLU76 4.6 2.0 1.0 O B:SER69 4.7 8.2 1.0 CA B:SER69 4.7 5.8 1.0 CA B:LEU71 4.8 6.9 1.0 N B:LEU71 4.8 9.2 1.0 CB B:LYS68 4.8 3.4 1.0 H B:GLY73 4.9 0.0 1.0 CB B:SER72 4.9 9.7 1.0 CB D:THR103 4.9 5.5 1.0 H D:THR103 4.9 0.0 1.0 C B:SER69 4.9 5.8 1.0

Calcium binding site 5 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca317 b:15.2 occ:1.00 OE2 E:GLU105 2.1 28.8 1.0 OE2 A:GLU76 2.1 2.0 1.0 O A:LYS68 2.2 2.1 1.0 O A:LEU71 2.4 2.6 1.0 CD E:GLU105 3.2 28.5 1.0 CD A:GLU76 3.3 3.1 1.0 C A:LYS68 3.4 3.2 1.0 C A:LEU71 3.6 2.1 1.0 OE1 A:GLU76 3.7 6.6 1.0 CG E:GLU105 3.8 23.6 1.0 OD2 E:ASP230 4.1 18.7 1.0 CA A:LYS68 4.2 2.3 1.0 OG A:SER72 4.2 19.1 1.0 CA A:SER72 4.2 7.9 1.0 OE1 E:GLU105 4.2 27.6 1.0 H A:LEU71 4.3 0.0 1.0 N A:SER72 4.3 2.0 1.0 N A:SER69 4.5 2.0 1.0 CG A:GLU76 4.5 2.0 1.0 HG A:SER72 4.5 0.0 1.0 CA A:SER69 4.6 4.5 1.0 N A:LEU71 4.7 3.2 1.0 CA A:LEU71 4.7 2.0 1.0 CB A:LYS68 4.7 2.0 1.0 O A:SER69 4.8 11.4 1.0 CB A:SER72 4.8 10.7 1.0 C A:SER69 4.8 10.2 1.0 OD1 E:ASP230 4.8 16.6 1.0 CB E:THR103 4.9 7.3 1.0 H A:GLY73 4.9 0.0 1.0 OG1 E:THR103 4.9 8.9 1.0 CG E:ASP230 4.9 12.8 1.0

Calcium binding site 6 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca317 b:2.0 occ:1.00 OE2 F:GLU105 2.1 26.2 1.0 OE2 C:GLU76 2.1 2.0 1.0 O C:LEU71 2.2 2.0 1.0 O C:LYS68 2.2 7.9 1.0 CD F:GLU105 3.1 28.8 1.0 CD C:GLU76 3.3 2.0 1.0 C C:LEU71 3.4 2.0 1.0 C C:LYS68 3.4 4.8 1.0 CG F:GLU105 3.7 22.9 1.0 OE1 C:GLU76 3.8 2.0 1.0 OD2 F:ASP230 3.9 15.2 1.0 CA C:LYS68 4.1 3.0 1.0 CA C:SER72 4.1 7.1 1.0 OE1 F:GLU105 4.1 32.5 1.0 N C:SER72 4.1 4.6 1.0 OG C:SER72 4.2 12.8 1.0 HG C:SER72 4.3 0.0 1.0 H C:LEU71 4.4 0.0 1.0 N C:SER69 4.4 3.4 1.0 CG C:GLU76 4.5 2.0 1.0 CA C:LEU71 4.5 2.0 1.0 N C:LEU71 4.6 4.8 1.0 O C:SER69 4.6 7.0 1.0 CA C:SER69 4.7 6.0 1.0 OD1 F:ASP230 4.7 19.6 1.0 CB C:LYS68 4.7 2.4 1.0 CG F:ASP230 4.7 14.8 1.0 C C:SER69 4.7 5.4 1.0 O C:LEU67 4.8 2.0 1.0 CB C:SER72 4.8 6.0 1.0 CB F:THR103 4.8 2.0 1.0 H C:GLY73 4.9 0.0 1.0 OG1 F:THR103 5.0 2.0 1.0

Calcium binding site 7 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca318 b:17.4 occ:1.00 O A:GLY28 2.1 46.6 1.0 OE2 A:GLU70 2.2 21.4 1.0 O A:GLY30 2.2 26.3 1.0 OE1 A:GLU70 2.3 20.1 1.0 O A:MET26 2.5 15.4 1.0 CD A:GLU70 2.7 16.9 1.0 C A:GLY28 3.4 42.9 1.0 C A:GLY30 3.5 27.4 1.0 C A:MET26 3.7 17.0 1.0 N A:GLY30 4.0 40.5 1.0 C A:ILE29 4.1 42.3 1.0 CG A:GLU70 4.2 14.2 1.0 N A:ILE29 4.2 44.1 1.0 CA A:ILE29 4.2 45.7 1.0 H A:GLY30 4.3 0.0 1.0 N A:GLY28 4.3 37.6 1.0 O A:LYS27 4.4 36.0 1.0 CA A:GLY30 4.4 32.3 1.0 C A:LYS27 4.4 34.4 1.0 CA A:MET26 4.4 11.6 1.0 OG1 A:THR31 4.4 14.5 1.0 CA A:GLY28 4.4 39.7 1.0 N A:THR31 4.5 22.9 1.0 O A:ILE29 4.6 42.9 1.0 H A:GLY28 4.6 0.0 1.0 N A:LYS27 4.7 25.4 1.0 CA A:THR31 4.8 18.0 1.0 CB A:MET26 4.8 12.5 1.0 CA A:LYS27 4.9 33.5 1.0

Calcium binding site 8 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca318 b:7.8 occ:1.00 O B:GLY28 2.1 46.8 1.0 OE2 B:GLU70 2.1 21.4 1.0 O B:GLY30 2.3 26.9 1.0 O B:MET26 2.3 17.4 1.0 OE1 B:GLU70 2.4 18.1 1.0 CD B:GLU70 2.7 14.1 1.0 C B:GLY28 3.4 41.8 1.0 C B:GLY30 3.5 26.3 1.0 C B:MET26 3.5 16.4 1.0 N B:GLY30 4.0 37.4 1.0 C B:ILE29 4.1 42.5 1.0 CG B:GLU70 4.2 12.6 1.0 N B:GLY28 4.2 35.7 1.0 CA B:MET26 4.2 12.1 1.0 N B:ILE29 4.3 43.0 1.0 H B:GLY30 4.3 0.0 1.0 C B:LYS27 4.3 32.0 1.0 O B:LYS27 4.3 31.6 1.0 CA B:ILE29 4.3 44.0 1.0 CA B:GLY30 4.3 30.7 1.0 CA B:GLY28 4.4 39.1 1.0 O B:ILE29 4.4 44.3 1.0 N B:THR31 4.5 23.3 1.0 H B:GLY28 4.5 0.0 1.0 N B:LYS27 4.5 24.1 1.0 OG1 B:THR31 4.6 16.3 1.0 CB B:MET26 4.7 11.0 1.0 CA B:LYS27 4.8 30.9 1.0 CA B:THR31 4.8 17.0 1.0

Calcium binding site 9 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca318 b:28.5 occ:1.00 O C:GLY30 2.0 33.0 1.0 OE1 C:GLU70 2.2 14.4 1.0 O C:GLY28 2.2 48.5 1.0 OE2 C:GLU70 2.2 25.4 1.0 O C:MET26 2.4 23.1 1.0 CD C:GLU70 2.6 15.3 1.0 C C:GLY30 3.3 31.3 1.0 C C:GLY28 3.4 47.0 1.0 C C:MET26 3.5 21.2 1.0 N C:GLY30 4.0 39.3 1.0 CG C:GLU70 4.1 13.7 1.0 C C:ILE29 4.1 42.8 1.0 CA C:MET26 4.2 16.5 1.0 N C:THR31 4.2 25.9 1.0 CA C:GLY30 4.3 35.3 1.0 O C:LYS27 4.3 33.3 1.0 N C:ILE29 4.3 48.5 1.0 OG1 C:THR31 4.3 21.7 1.0 H C:GLY30 4.3 0.0 1.0 C C:LYS27 4.4 34.5 1.0 CA C:ILE29 4.4 46.8 1.0 N C:GLY28 4.4 37.7 1.0 O C:ILE29 4.5 43.4 1.0 CA C:THR31 4.5 20.0 1.0 CA C:GLY28 4.5 43.2 1.0 N C:LYS27 4.6 25.4 1.0 CB C:MET26 4.6 10.8 1.0 H C:GLY28 4.8 0.0 1.0 CA C:LYS27 4.9 31.4 1.0 CB C:THR31 4.9 18.0 1.0 CB C:GLU70 5.0 9.3 1.0

Calcium binding site 10 out of 24 in the Crystal Structure of the Annexin XII Hexamer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Crystal Structure of the Annexin XII Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca318 b:21.8 occ:1.00 OE2 D:GLU70 2.1 24.8 1.0 OE1 D:GLU70 2.1 19.7 1.0 O D:GLY30 2.2 32.5 1.0 O D:GLY28 2.3 48.7 1.0 O D:MET26 2.5 12.4 1.0 CD D:GLU70 2.5 18.4 1.0 C D:GLY30 3.5 30.2 1.0 C D:GLY28 3.5 45.0 1.0 C D:MET26 3.7 16.2 1.0 N D:GLY30 4.0 40.0 1.0 CG D:GLU70 4.1 16.2 1.0 C D:ILE29 4.1 43.5 1.0 H D:GLY30 4.3 0.0 1.0 N D:ILE29 4.3 47.0 1.0 CA D:ILE29 4.3 46.2 1.0 CA D:GLY30 4.4 34.2 1.0 CA D:MET26 4.4 12.8 1.0 N D:THR31 4.4 24.1 1.0 OG1 D:THR31 4.4 24.4 1.0 O D:LYS27 4.5 36.4 1.0 C D:LYS27 4.5 34.7 1.0 N D:GLY28 4.5 37.2 1.0 O D:ILE29 4.5 45.6 1.0 CA D:GLY28 4.6 41.5 1.0 CA D:THR31 4.7 20.4 1.0 N D:LYS27 4.8 21.5 1.0 CB D:MET26 4.8 12.2 1.0 H D:GLY28 4.9 0.0 1.0 CB D:GLU70 4.9 6.3 1.0

H.Luecke, B.T.Chang, W.S.Mailliard, D.D.Schlaepfer, H.T.Haigler. Crystal Structure of the Annexin XII Hexamer and Implications For Bilayer Insertion. Nature V. 378 512 1995.
ISSN: ISSN 0028-0836
PubMed: 7477411
DOI: 10.1038/378512A0