Calcium in PDB 1aii: Annexin III

The structure of Annexin III, PDB code: 1aii was solved by A.Lewit-Bentley, B.Perron, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.95
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.290, 68.720, 50.590, 90.00, 94.27, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Calcium atom in the Annexin III (pdb code 1aii). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Annexin III, PDB code: 1aii:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the Annexin III


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Annexin III within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca351 b:34.4 occ:0.70 O A:GLY34 2.6 36.2 1.0 O A:ILE32 2.7 27.6 1.0 O A:GLY36 2.9 33.4 1.0 OD1 A:ASP76 2.9 37.5 1.0 OD2 A:ASP76 3.0 35.9 1.0 CG A:ASP76 3.3 33.1 1.0 O3 A:SO4361 3.5 48.9 0.5 OG1 A:THR37 3.7 23.2 1.0 C A:ILE32 3.7 26.9 1.0 C A:GLY36 3.7 33.5 1.0 O2 A:SO4361 3.7 47.2 0.5 C A:GLY34 3.8 36.3 1.0 N A:GLY36 4.1 36.5 1.0 C A:ILE35 4.2 37.4 1.0 S A:SO4361 4.3 47.4 0.5 O A:ARG33 4.4 28.8 1.0 C A:ARG33 4.4 30.6 1.0 CA A:ILE32 4.4 24.3 1.0 CA A:ILE35 4.5 38.1 1.0 N A:GLY34 4.5 32.6 1.0 O A:HOH490 4.5 28.2 1.0 CA A:GLY36 4.5 35.5 1.0 N A:THR37 4.5 29.6 1.0 N A:ARG33 4.6 28.0 1.0 N A:ILE35 4.6 37.5 1.0 O A:ILE35 4.7 38.6 1.0 CA A:THR37 4.7 24.9 1.0 O A:HOH606 4.8 37.0 1.0 CB A:THR37 4.8 23.6 1.0 CA A:GLY34 4.8 34.8 1.0 CA A:ARG33 4.8 29.4 1.0 CB A:ASP76 4.8 26.6 1.0

Calcium binding site 2 out of 5 in the Annexin III


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Annexin III within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca353 b:12.3 occ:1.00 O A:GLY192 2.4 5.7 1.0 O A:ARG190 2.6 12.4 1.0 OE1 A:GLU232 2.6 5.0 1.0 O A:GLY187 2.6 10.5 1.0 O A:HOH409 2.7 9.8 1.0 O A:HOH576 2.7 15.5 1.0 OE2 A:GLU232 2.8 9.7 1.0 CD A:GLU232 3.0 8.4 1.0 C A:GLY187 3.5 12.0 1.0 C A:GLY192 3.5 5.7 1.0 C A:ARG190 3.7 14.2 1.0 N A:GLY192 3.8 11.8 1.0 CA A:GLY187 4.1 10.5 1.0 C A:TRP191 4.2 12.7 1.0 OG1 A:THR193 4.2 14.6 1.0 CA A:GLY192 4.2 10.9 1.0 N A:GLU188 4.2 11.8 1.0 O A:HOH489 4.3 35.7 1.0 N A:ARG190 4.3 13.0 1.0 O A:GLU188 4.4 15.8 1.0 CA A:GLU188 4.5 12.9 1.0 O A:HOH410 4.5 19.0 1.0 CA A:TRP191 4.5 13.7 1.0 C A:GLU188 4.5 16.0 1.0 CG A:ARG190 4.5 11.0 1.0 CG A:GLU232 4.5 10.5 1.0 N A:TRP191 4.6 13.9 1.0 N A:THR193 4.6 10.1 1.0 CA A:ARG190 4.6 13.0 1.0 O A:HOH470 4.7 31.1 1.0 O A:TRP191 4.8 12.5 1.0 CA A:THR193 4.8 10.1 1.0

Calcium binding site 3 out of 5 in the Annexin III


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Annexin III within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca354 b:44.4 occ:0.30 O A:LYS230 2.8 13.9 1.0 O A:LEU233 2.9 13.4 1.0 O A:HOH534 3.1 39.0 1.0 OE1 A:GLU238 3.2 15.7 1.0 OE2 A:GLU238 3.2 17.9 1.0 CD A:GLU238 3.4 14.6 1.0 C A:LYS230 3.8 14.3 1.0 C A:LEU233 4.1 13.0 1.0 CA A:LYS230 4.1 16.4 1.0 CA A:SER234 4.2 15.5 1.0 CB A:SER234 4.3 19.8 1.0 CG A:GLU238 4.6 11.3 1.0 N A:SER234 4.6 13.8 1.0 CB A:LYS230 4.6 17.5 1.0 CG A:LYS230 4.7 24.4 1.0 O A:ILE229 4.9 13.1 1.0

Calcium binding site 4 out of 5 in the Annexin III


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Annexin III within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca355 b:40.7 occ:0.50 N A:ETA360 2.3 45.7 0.5 O A:HOH633 2.9 42.0 1.0 OE1 A:GLU195 2.9 13.8 1.0 O A:THR193 3.0 8.7 1.0 OE2 A:GLU195 3.3 18.7 1.0 CA A:ETA360 3.3 46.4 1.0 N A:ETA360 3.4 45.6 0.5 CD A:GLU195 3.4 16.9 1.0 C A:THR193 4.2 9.8 1.0 CB A:ETA360 4.3 46.8 1.0 N A:THR193 4.4 10.1 1.0 O A:HOH572 4.4 39.7 1.0 O A:HOH552 4.4 36.9 1.0 O A:ETA360 4.7 48.2 1.0 O A:HOH621 4.8 49.4 1.0 NH2 A:ARG190 4.8 14.2 1.0 CA A:THR193 4.8 10.1 1.0 O A:HOH553 4.9 33.2 1.0 CG A:GLU195 4.9 13.4 1.0 O A:HOH412 4.9 38.8 1.0

Calcium binding site 5 out of 5 in the Annexin III


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Annexin III within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca357 b:42.6 occ:0.40 O A:GLY106 2.8 56.3 1.0 O A:MET104 2.8 39.8 1.0 OE1 A:GLU148 2.9 29.1 1.0 O A:GLY108 2.9 44.0 1.0 C A:MET104 3.2 37.7 1.0 CD A:GLU148 3.5 29.1 1.0 C A:LYS105 3.6 51.6 1.0 N A:LYS105 3.6 44.6 1.0 C A:GLY106 3.7 56.0 1.0 N A:GLY106 3.7 53.6 1.0 CA A:LYS105 3.8 50.3 1.0 OG1 A:THR109 3.8 30.7 1.0 OE2 A:GLU148 4.0 31.0 1.0 CA A:MET104 4.0 33.7 1.0 O A:LYS105 4.0 50.8 1.0 C A:GLY108 4.1 42.7 1.0 O A:ALA107 4.2 52.6 1.0 CG A:GLU148 4.3 25.5 1.0 CA A:GLY106 4.3 55.7 1.0 C A:ALA107 4.4 52.5 1.0 CB A:MET104 4.7 29.6 1.0 N A:ALA107 4.7 55.5 1.0 N A:GLY108 4.8 50.2 1.0 CA A:THR109 4.8 30.4 1.0 CA A:ALA107 4.9 54.0 1.0 N A:THR109 4.9 37.2 1.0 CB A:GLU148 4.9 22.3 1.0 CB A:THR109 4.9 30.5 1.0

B.Perron, A.Lewit-Bentley, B.Geny, F.Russo-Marie. Can Enzymatic Activity, or Otherwise, Be Inferred From Structural Studies of Annexin III? J.Biol.Chem. V. 272 11321 1997.
ISSN: ISSN 0021-9258
PubMed: 9111038
DOI: 10.1074/JBC.272.17.11321