Calcium in PDB 1axn: The High Resolution Structure of Annexin III Shows Differences with Annexin V

The structure of The High Resolution Structure of Annexin III Shows Differences with Annexin V, PDB code: 1axn was solved by B.Favier-Perron, A.Lewit-Bentley, F.Russo-Marie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 1.78
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.544, 69.085, 50.950, 90.00, 95.55, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Calcium atom in the The High Resolution Structure of Annexin III Shows Differences with Annexin V (pdb code 1axn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the The High Resolution Structure of Annexin III Shows Differences with Annexin V, PDB code: 1axn:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the The High Resolution Structure of Annexin III Shows Differences with Annexin V


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The High Resolution Structure of Annexin III Shows Differences with Annexin V within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca351 b:36.6 occ:0.70 O A:GLY36 2.2 33.3 1.0 O A:ILE32 2.3 30.4 1.0 O A:GLY34 2.6 40.5 1.0 OD2 A:ASP76 2.7 34.1 1.0 OD1 A:ASP76 3.1 34.9 1.0 CG A:ASP76 3.3 32.4 1.0 C A:GLY36 3.3 32.5 1.0 C A:ILE32 3.4 30.5 1.0 OG1 A:THR37 3.5 24.8 1.0 C A:GLY34 3.7 39.0 1.0 N A:GLY36 3.9 37.0 1.0 O A:HOH534 3.9 38.5 1.0 CA A:ILE32 4.1 28.7 1.0 C A:ILE35 4.2 38.2 1.0 CA A:GLY36 4.2 34.8 1.0 N A:GLY34 4.2 37.4 1.0 C A:ARG33 4.3 36.9 1.0 N A:THR37 4.3 29.6 1.0 O A:ARG33 4.4 37.2 1.0 N A:ARG33 4.4 32.7 1.0 CA A:THR37 4.5 25.9 1.0 CA A:GLY34 4.5 39.0 1.0 N A:ILE35 4.5 39.4 1.0 CA A:ILE35 4.5 39.8 1.0 O A:HOH619 4.6 48.0 1.0 CB A:THR37 4.6 24.6 1.0 CB A:ILE32 4.6 29.5 1.0 O A:ILE35 4.7 39.8 1.0 CB A:ASP76 4.7 27.9 1.0 CA A:ARG33 4.7 35.6 1.0

Calcium binding site 2 out of 5 in the The High Resolution Structure of Annexin III Shows Differences with Annexin V


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of The High Resolution Structure of Annexin III Shows Differences with Annexin V within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca352 b:37.4 occ:0.30 O A:GLY106 2.4 46.9 1.0 O A:GLY108 2.4 39.0 1.0 O A:MET104 2.4 31.4 1.0 OE1 A:GLU148 2.9 26.2 1.0 C A:MET104 3.3 29.6 1.0 C A:GLY106 3.3 46.2 1.0 OG1 A:THR109 3.4 31.8 1.0 C A:GLY108 3.4 38.0 1.0 N A:GLY106 3.7 43.9 1.0 CD A:GLU148 3.7 25.7 1.0 C A:LYS105 3.8 41.4 1.0 O A:HOH615 3.8 51.5 1.0 N A:GLY108 4.0 43.6 1.0 CA A:GLY106 4.0 45.8 1.0 O A:LYS105 4.1 41.5 1.0 CA A:MET104 4.1 25.9 1.0 N A:LYS105 4.1 34.5 1.0 CG A:GLU148 4.2 23.4 1.0 N A:THR109 4.2 34.6 1.0 CA A:LYS105 4.3 39.5 1.0 N A:ALA107 4.3 46.4 1.0 CA A:THR109 4.4 30.4 1.0 CA A:GLY108 4.4 40.6 1.0 CB A:THR109 4.5 29.6 1.0 OE2 A:GLU148 4.6 25.9 1.0 CB A:GLU148 4.6 22.1 1.0 CA A:ALA107 4.7 46.3 1.0 CB A:MET104 4.8 23.4 1.0 C A:ALA107 4.9 45.5 1.0

Calcium binding site 3 out of 5 in the The High Resolution Structure of Annexin III Shows Differences with Annexin V


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of The High Resolution Structure of Annexin III Shows Differences with Annexin V within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca353 b:11.8 occ:1.00 O A:GLY192 2.3 9.2 1.0 O A:GLY187 2.3 16.7 1.0 OE1 A:GLU232 2.4 13.3 1.0 O A:ARG190 2.4 14.8 1.0 OE2 A:GLU232 2.5 16.4 1.0 O A:HOH407 2.6 15.2 1.0 O A:HOH406 2.7 20.4 1.0 CD A:GLU232 2.8 14.7 1.0 C A:GLY187 3.3 16.9 1.0 C A:GLY192 3.4 10.0 1.0 C A:ARG190 3.6 16.1 1.0 N A:GLY192 3.7 11.1 1.0 C A:TRP191 4.1 12.4 1.0 CA A:GLY192 4.1 11.2 1.0 CA A:GLY187 4.1 15.4 1.0 N A:GLU188 4.2 18.0 1.0 OG1 A:THR193 4.2 15.6 1.0 CG A:GLU232 4.3 15.1 1.0 N A:ARG190 4.3 18.1 1.0 CA A:GLU188 4.4 20.2 1.0 CG A:ARG190 4.4 16.6 1.0 CA A:TRP191 4.5 14.7 1.0 N A:THR193 4.5 10.7 1.0 CA A:ARG190 4.5 15.8 1.0 N A:TRP191 4.5 15.0 1.0 O A:HOH478 4.5 21.5 1.0 O A:GLU188 4.5 22.5 1.0 C A:GLU188 4.5 20.7 1.0 O A:TRP191 4.7 12.1 1.0 CA A:THR193 4.7 11.5 1.0 O A:HOH489 5.0 30.5 1.0

Calcium binding site 4 out of 5 in the The High Resolution Structure of Annexin III Shows Differences with Annexin V


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of The High Resolution Structure of Annexin III Shows Differences with Annexin V within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca354 b:37.4 occ:0.30 O A:LEU233 2.4 17.0 1.0 O A:LYS230 2.5 16.2 1.0 O A:HOH580 3.0 34.3 1.0 OE2 A:GLU238 3.1 17.7 1.0 OE1 A:GLU238 3.2 17.1 1.0 CD A:GLU238 3.2 16.2 1.0 C A:LYS230 3.6 16.2 1.0 C A:LEU233 3.6 15.3 1.0 CA A:LYS230 4.0 15.9 1.0 CA A:SER234 4.1 16.2 1.0 CG A:GLU238 4.3 11.4 1.0 N A:SER234 4.3 15.0 1.0 CB A:SER234 4.4 18.8 1.0 O A:ILE229 4.6 12.6 1.0 CB A:LYS230 4.7 18.5 1.0 CA A:LEU233 4.8 15.0 1.0 N A:GLY231 4.8 16.2 1.0 N A:LEU233 4.8 15.4 1.0 O A:HOH605 4.9 36.9 1.0 O A:HOH542 5.0 31.8 1.0

Calcium binding site 5 out of 5 in the The High Resolution Structure of Annexin III Shows Differences with Annexin V


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of The High Resolution Structure of Annexin III Shows Differences with Annexin V within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca355 b:32.2 occ:0.50 O A:THR193 2.4 11.2 1.0 OE1 A:GLU195 2.5 13.0 1.0 O A:HOH603 2.8 39.4 1.0 O A:HOH458 2.8 37.5 1.0 OE2 A:GLU195 3.0 15.4 1.0 CD A:GLU195 3.1 14.1 1.0 C A:THR193 3.6 10.6 1.0 O A:HOH456 4.1 30.7 1.0 N A:THR193 4.2 10.7 1.0 O A:HOH547 4.4 38.4 1.0 CA A:THR193 4.4 11.5 1.0 N A:GLU195 4.5 12.2 1.0 N A:ASP194 4.6 11.1 1.0 O A:HOH546 4.6 32.4 1.0 CG A:GLU195 4.6 13.3 1.0 CA A:ASP194 4.6 12.3 1.0 CB A:THR193 4.7 13.7 1.0 NH2 A:ARG190 4.8 20.1 1.0

B.Favier-Perron, A.Lewit-Bentley, F.Russo-Marie. The High-Resolution Crystal Structure of Human Annexin III Shows Subtle Differences with Annexin V. Biochemistry V. 35 1740 1996.
ISSN: ISSN 0006-2960
PubMed: 8639653
DOI: 10.1021/BI952092O