Atomistry » Calcium » PDB 1byn-1c5v » 1c2f
Atomistry »
  Calcium »
    PDB 1byn-1c5v »
      1c2f »

Calcium in PDB 1c2f: Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases

Enzymatic activity of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases

All present enzymatic activity of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases:
3.4.21.4;

Protein crystallography data

The structure of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases, PDB code: 1c2f was solved by B.A.Katz, C.Luong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 7.50 / 1.70
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 54.990, 54.990, 109.920, 90.00, 90.00, 120.00
R / Rfree (%) 19 / 24.1

Other elements in 1c2f:

The structure of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Zinc (Zn) 3 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases (pdb code 1c2f). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases, PDB code: 1c2f:

Calcium binding site 1 out of 1 in 1c2f

Go back to Calcium Binding Sites List in 1c2f
Calcium binding site 1 out of 1 in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca247

b:30.5
occ:1.00
 H2 A:HOH309 2.0 28.0 1.0
O A:VAL75 2.3 22.6 1.0
O A:ASN72 2.4 7.6 1.0
OE2 A:GLU80 2.4 15.1 1.0
OE1 A:GLU70 2.4 18.1 1.0
O A:HOH309 2.6 27.5 1.0
O A:HOH271 2.6 21.2 1.0
H1 A:HOH309 3.0 27.9 1.0
H A:GLU77 3.0 20.3 1.0
H2 A:HOH271 3.2 22.2 1.0
HG2 A:GLU80 3.3 16.9 1.0
HA A:VAL76 3.3 17.4 1.0
H1 A:HOH271 3.3 21.4 1.0
C A:VAL75 3.3 16.4 1.0
HA A:ILE73 3.4 12.3 1.0
CD A:GLU70 3.4 21.5 1.0
CD A:GLU80 3.5 17.8 1.0
H A:VAL75 3.5 17.3 1.0
H A:ASP71 3.5 21.5 1.0
C A:ASN72 3.5 13.3 1.0
HG3 A:GLU77 3.6 26.9 1.0
H A:ASN72 3.7 14.8 1.0
CG A:GLU80 3.7 17.5 1.0
HA A:GLU70 3.8 18.3 1.0
HG3 A:GLU80 3.8 17.6 1.0
OE2 A:GLU70 3.9 20.9 1.0
HB3 A:ASN72 3.9 15.1 1.0
N A:GLU77 3.9 17.3 1.0
HB2 A:GLU77 4.0 23.4 1.0
CA A:VAL76 4.1 18.8 1.0
N A:VAL76 4.1 14.6 1.0
N A:VAL75 4.1 15.7 1.0
OE1 A:GLU77 4.1 28.7 1.0
N A:ASN72 4.2 14.4 1.0
CA A:ILE73 4.2 12.4 1.0
CA A:VAL75 4.2 14.9 1.0
HB A:VAL75 4.3 14.8 1.0
N A:ILE73 4.3 10.3 1.0
O A:HOH267 4.3 19.4 1.0
CG A:GLU77 4.4 25.6 1.0
CA A:ASN72 4.4 15.8 1.0
N A:ASP71 4.5 20.9 1.0
C A:ILE73 4.5 14.2 1.0
OE1 A:GLU80 4.5 15.8 1.0
C A:VAL76 4.5 20.3 1.0
HB3 A:GLU70 4.6 18.8 1.0
CB A:GLU77 4.6 22.7 1.0
CB A:ASN72 4.6 14.2 1.0
H1 A:HOH267 4.7 24.2 1.0
CA A:GLU70 4.7 18.9 1.0
HZ A:PHE82 4.7 18.7 1.0
CG A:GLU70 4.7 19.3 1.0
CD A:GLU77 4.8 28.4 1.0
H A:ASN74 4.8 13.9 1.0
N A:ASN74 4.8 12.7 1.0
CB A:VAL75 4.9 13.3 1.0
CB A:GLU70 4.9 19.3 1.0
H2 A:HOH267 4.9 23.0 1.0
CA A:GLU77 5.0 22.2 1.0
O A:ILE73 5.0 13.7 1.0
C A:ASP71 5.0 22.2 1.0
H A:VAL76 5.0 16.6 1.0

Reference:

B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud. Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors. Nature V. 391 608 1998.
ISSN: ISSN 0028-0836
PubMed: 9468142
DOI: 10.1038/35422
Page generated: Thu Jul 11 06:48:50 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy