Atomistry » Calcium » PDB 1dva-1edh » 1e7m
Atomistry »
  Calcium »
    PDB 1dva-1edh »
      1e7m »

Calcium in PDB 1e7m: Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides

Enzymatic activity of Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides

All present enzymatic activity of Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides:
1.1.1.49;

Protein crystallography data

The structure of Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides, PDB code: 1e7m was solved by M.J.Adams, M.S.Cosgrove, S.Gover, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.20 / 2.54
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 130.300, 44.400, 92.800, 90.00, 106.70, 90.00
R / Rfree (%) 22.2 / 29.9

Calcium Binding Sites:

The binding sites of Calcium atom in the Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides (pdb code 1e7m). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides, PDB code: 1e7m:

Calcium binding site 1 out of 1 in 1e7m

Go back to Calcium Binding Sites List in 1e7m
Calcium binding site 1 out of 1 in the Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Active Site Mutant (D177->N) of Glucose 6-Phosphate Dehydrogenase From Leuconostoc Mesenteroides within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca800

b:62.5
occ:1.00
 O A:HOH2041 2.2 43.3 1.0
OD1 A:ASN477 2.3 41.3 1.0
CG A:ASN477 3.3 37.5 1.0
O A:HOH2040 3.3 29.6 1.0
ND2 A:ASN477 3.7 38.2 1.0
O A:HOH2039 3.9 38.0 1.0
OE1 A:GLU319 3.9 22.8 1.0
CE1 A:TYR283 4.0 43.1 1.0
OE2 A:GLU319 4.3 22.0 1.0
CD A:GLU319 4.6 25.3 1.0
OH A:TYR283 4.6 47.1 1.0
CB A:ASN477 4.7 36.8 1.0
O A:ALA476 4.7 27.6 1.0
CE A:LYS282 4.8 48.9 1.0
CZ A:TYR283 4.8 44.9 1.0
CD1 A:TYR283 4.8 41.0 1.0
C A:ALA476 5.0 31.4 1.0

Reference:

M.S.Cosgrove, S.Gover, C.E.Naylor, L.Vandeputte-Rutten, M.J.Adams, H.R.Levy. An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and pH Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry V. 39 15002 2000.
ISSN: ISSN 0006-2960
PubMed: 11106478
DOI: 10.1021/BI0014608
Page generated: Thu Jul 11 07:47:07 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy