Calcium in PDB 1f0s: Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707

All present enzymatic activity of Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707:
3.4.21.6;

The structure of Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707, PDB code: 1f0s was solved by S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.660, 71.580, 78.700, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 26.3

The binding sites of Calcium atom in the Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707 (pdb code 1f0s). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707, PDB code: 1f0s:

Calcium binding site 1 out of 1 in the Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human Coagulation Factor Xa Complexed with RPR208707 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca301 b:48.5 occ:1.00 OE1 A:GLU80 2.4 31.2 1.0 O A:ASN72 2.4 41.7 1.0 OD1 A:ASP70 2.5 39.0 1.0 O A:HOH468 2.6 33.5 1.0 O A:HOH488 2.7 42.2 1.0 O A:GLN75 2.9 66.5 1.0 C A:ASN72 3.3 33.9 1.0 CD A:GLU80 3.4 27.9 1.0 C A:GLN75 3.6 61.7 1.0 CG A:ASP70 3.7 36.5 1.0 N A:ASN72 3.7 32.2 1.0 CG A:GLU80 3.9 25.8 1.0 N A:GLU77 3.9 61.2 1.0 CA A:ASN72 4.0 32.5 1.0 N A:THR73 4.1 35.1 1.0 CA A:GLU76 4.1 62.3 1.0 N A:GLU76 4.2 61.9 1.0 CA A:THR73 4.3 37.3 1.0 N A:ARG71 4.3 25.3 1.0 CB A:ASN72 4.3 32.2 1.0 N A:GLN75 4.3 55.9 1.0 OD2 A:ASP70 4.4 43.1 1.0 OE2 A:GLU80 4.5 32.6 1.0 C A:GLU76 4.6 62.1 1.0 CA A:GLN75 4.6 58.3 1.0 CB A:GLU77 4.6 55.5 1.0 CA A:ASP70 4.7 30.7 1.0 C A:THR73 4.8 41.5 1.0 N A:GLU74 4.8 46.2 1.0 CB A:ASP70 4.8 36.0 1.0 CA A:GLU77 4.9 58.0 1.0 C A:ARG71 4.9 26.9 1.0

S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors. J.Med.Chem. V. 43 3226 2000.
ISSN: ISSN 0022-2623
PubMed: 10966741
DOI: 10.1021/JM000940U