Calcium in PDB 1f0t: Bovine Trypsin Complexed with RPR131247

All present enzymatic activity of Bovine Trypsin Complexed with RPR131247:
3.4.21.4;

The structure of Bovine Trypsin Complexed with RPR131247, PDB code: 1f0t was solved by S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.440, 63.830, 69.360, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / n/a

The binding sites of Calcium atom in the Bovine Trypsin Complexed with RPR131247 (pdb code 1f0t). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Bovine Trypsin Complexed with RPR131247, PDB code: 1f0t:

Calcium binding site 1 out of 1 in the Bovine Trypsin Complexed with RPR131247


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Bovine Trypsin Complexed with RPR131247 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca301 b:23.8 occ:1.00 O A:VAL75 2.1 18.6 1.0 O A:HOH326 2.3 18.5 1.0 O A:ASN72 2.3 16.2 1.0 OE1 A:GLU70 2.3 21.6 1.0 O A:HOH316 2.4 15.2 1.0 OE2 A:GLU80 2.4 16.1 1.0 C A:VAL75 3.3 18.7 1.0 CD A:GLU80 3.4 17.4 1.0 CD A:GLU70 3.4 19.6 1.0 C A:ASN72 3.5 15.8 1.0 CG A:GLU80 3.7 18.1 1.0 OE2 A:GLU70 3.8 24.1 1.0 CA A:VAL76 4.0 19.4 1.0 N A:VAL76 4.1 18.0 1.0 OE1 A:GLU77 4.1 27.0 1.0 CG A:GLU77 4.2 23.5 1.0 N A:VAL75 4.2 18.7 1.0 N A:GLU77 4.2 20.5 1.0 CA A:ILE73 4.3 15.0 1.0 N A:ASN72 4.3 16.2 1.0 CA A:VAL75 4.3 20.1 1.0 N A:ILE73 4.3 14.8 1.0 CA A:ASN72 4.4 16.4 1.0 O A:HOH323 4.5 17.5 1.0 C A:ILE73 4.5 15.8 1.0 OE1 A:GLU80 4.5 17.9 1.0 C A:VAL76 4.6 21.5 1.0 CB A:ASN72 4.6 16.3 1.0 CD A:GLU77 4.6 27.1 1.0 O A:HOH337 4.6 21.3 1.0 CG A:GLU70 4.7 18.3 1.0 N A:ASP71 4.7 15.4 1.0 N A:ASN74 4.8 17.6 1.0 CA A:GLU70 4.9 14.9 1.0 O A:ILE73 5.0 15.3 1.0 CB A:GLU70 5.0 15.1 1.0

S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors. J.Med.Chem. V. 43 3226 2000.
ISSN: ISSN 0022-2623
PubMed: 10966741
DOI: 10.1021/JM000940U