Calcium in PDB 1ggz: Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells

The structure of Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells, PDB code: 1ggz was solved by B.-G.Han, M.Han, H.Sui, P.Yaswen, P.J.Walian, B.K.Jap, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.50
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.380, 93.630, 24.860, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 22.1

The binding sites of Calcium atom in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells (pdb code 1ggz). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells, PDB code: 1ggz:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca149 b:8.4 occ:1.00 O A:CYS26 2.3 12.6 1.0 OD1 A:ASP20 2.3 10.4 1.0 OD1 A:ASP22 2.4 11.3 1.0 OD1 A:ASP24 2.4 11.6 1.0 O A:HOH153 2.4 11.2 1.0 OE1 A:GLU31 2.4 9.5 1.0 OE2 A:GLU31 2.5 9.3 1.0 CD A:GLU31 2.8 10.5 1.0 CG A:ASP24 3.3 15.1 1.0 CG A:ASP22 3.4 13.3 1.0 CG A:ASP20 3.5 9.8 1.0 C A:CYS26 3.5 11.2 1.0 OD2 A:ASP22 3.6 14.2 1.0 OD2 A:ASP24 3.9 17.0 1.0 N A:ASP24 4.1 11.4 1.0 N A:CYS26 4.2 10.7 1.0 OD2 A:ASP20 4.3 11.4 1.0 CA A:ASP20 4.3 9.6 1.0 CG A:GLU31 4.3 9.5 1.0 N A:ASP22 4.3 10.3 1.0 CB A:ASP24 4.4 13.5 1.0 N A:ILE27 4.4 8.0 1.0 CB A:ASP20 4.4 9.3 1.0 CA A:CYS26 4.4 12.6 1.0 C A:ASP20 4.4 11.1 1.0 O A:HOH180 4.4 13.6 1.0 CA A:ILE27 4.5 9.4 1.0 SG A:CYS26 4.5 17.0 1.0 N A:LYS21 4.6 12.2 1.0 CB A:ASP22 4.6 12.8 1.0 N A:GLY23 4.6 12.2 1.0 O A:HOH163 4.6 12.3 1.0 CA A:ASP24 4.6 11.6 1.0 N A:THR28 4.7 8.1 1.0 CA A:ASP22 4.8 12.0 1.0 N A:GLY25 4.8 11.2 1.0 CG2 A:THR28 4.8 11.1 1.0 O A:HOH161 4.8 13.9 1.0 C A:ASP22 4.9 13.4 1.0 O A:ASP20 4.9 11.3 1.0 C A:ASP24 5.0 10.9 1.0

Calcium binding site 2 out of 4 in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca150 b:10.6 occ:1.00 O A:THR62 2.3 11.6 1.0 OD1 A:ASP56 2.3 12.5 1.0 O A:HOH154 2.4 18.3 1.0 OD1 A:ASP58 2.4 12.6 1.0 OE1 A:GLU67 2.4 13.4 1.0 OD1 A:ASN60 2.4 13.1 1.0 OE2 A:GLU67 2.5 12.0 1.0 CD A:GLU67 2.9 14.4 1.0 CG A:ASN60 3.3 11.5 1.0 CG A:ASP58 3.4 14.9 1.0 CG A:ASP56 3.5 15.3 1.0 C A:THR62 3.5 10.3 1.0 ND2 A:ASN60 3.9 13.6 1.0 OD2 A:ASP58 3.9 20.9 1.0 N A:ASN60 4.2 13.3 1.0 O A:HOH185 4.2 18.6 1.0 OD2 A:ASP56 4.2 15.3 1.0 N A:THR62 4.2 12.7 1.0 N A:ASP58 4.3 11.9 1.0 CA A:ASP56 4.3 13.0 1.0 CG A:GLU67 4.3 10.8 1.0 CA A:VAL63 4.4 10.2 1.0 CB A:ASP56 4.4 14.0 1.0 CB A:ASN60 4.4 12.8 1.0 N A:VAL63 4.4 9.5 1.0 N A:GLY59 4.5 14.7 1.0 C A:ASP56 4.5 13.0 1.0 CA A:THR62 4.5 11.2 1.0 CB A:ASP58 4.6 14.6 1.0 N A:ARG57 4.6 12.0 1.0 N A:ASP64 4.6 9.6 1.0 O A:HOH231 4.6 26.1 1.0 OG1 A:THR62 4.7 12.3 1.0 CA A:ASN60 4.7 13.1 1.0 N A:GLY61 4.7 12.2 1.0 CA A:ASP58 4.8 13.1 1.0 C A:ASP58 4.9 15.2 1.0 O A:ASP56 4.9 15.4 1.0 C A:ASN60 4.9 12.5 1.0

Calcium binding site 3 out of 4 in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca151 b:9.7 occ:1.00 O A:PHE99 2.2 14.2 1.0 OD1 A:ASP93 2.3 12.7 1.0 O A:HOH155 2.4 19.2 1.0 OD1 A:ASP95 2.4 13.8 1.0 OD1 A:ASN97 2.4 13.7 1.0 OE1 A:GLU104 2.5 10.9 1.0 OE2 A:GLU104 2.5 11.2 1.0 CD A:GLU104 2.9 12.0 1.0 CG A:ASP95 3.3 14.3 1.0 CG A:ASN97 3.4 15.5 1.0 C A:PHE99 3.5 11.1 1.0 CG A:ASP93 3.5 13.3 1.0 OD2 A:ASP95 3.8 17.6 1.0 ND2 A:ASN97 3.9 18.0 1.0 N A:ASN97 4.2 13.6 1.0 N A:PHE99 4.2 11.6 1.0 CA A:ASP93 4.2 9.9 1.0 N A:ASP95 4.2 11.7 1.0 CG A:GLU104 4.4 8.8 1.0 OD2 A:ASP93 4.4 14.7 1.0 CB A:ASP93 4.4 8.8 1.0 CA A:PHE99 4.4 12.1 1.0 C A:ASP93 4.4 10.3 1.0 CB A:ASN97 4.4 16.2 1.0 N A:VAL100 4.4 9.1 1.0 CA A:VAL100 4.5 9.3 1.0 CB A:ASP95 4.5 13.4 1.0 N A:GLY96 4.5 14.7 1.0 N A:SER101 4.6 8.7 1.0 N A:LYS94 4.6 10.7 1.0 CA A:ASN97 4.7 12.8 1.0 CA A:ASP95 4.7 13.2 1.0 OE1 A:GLN135 4.8 24.6 1.0 C A:ASP95 4.8 15.2 1.0 CB A:PHE99 4.8 12.5 1.0 N A:GLY98 4.8 11.9 1.0 O A:ASP93 4.8 11.2 1.0 C A:VAL100 5.0 9.9 1.0

Calcium binding site 4 out of 4 in the Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of the Calmodulin-Like Protein (Hclp) From Human Epithelial Cells within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca152 b:11.6 occ:1.00 OD1 A:ASP131 2.3 13.0 1.0 O A:GLN135 2.3 14.3 1.0 OD1 A:ASP129 2.4 14.4 1.0 OD1 A:ASP133 2.4 16.4 1.0 O A:HOH156 2.5 16.5 1.0 OE1 A:GLU140 2.5 10.9 1.0 OE2 A:GLU140 2.6 11.4 1.0 CD A:GLU140 2.9 10.9 1.0 CG A:ASP131 3.2 14.3 1.0 CG A:ASP133 3.3 16.6 1.0 CG A:ASP129 3.4 14.0 1.0 C A:GLN135 3.6 12.8 1.0 OD2 A:ASP131 3.7 18.0 1.0 OD2 A:ASP133 3.8 19.8 1.0 N A:ASP133 4.2 19.5 1.0 CA A:ASP129 4.2 11.3 1.0 CB A:ASP129 4.2 12.8 1.0 N A:GLN135 4.2 14.2 1.0 OD2 A:ASP129 4.2 14.7 1.0 N A:ASP131 4.3 12.7 1.0 N A:ASN137 4.3 9.8 1.0 CA A:VAL136 4.4 9.9 1.0 CB A:ASP133 4.4 19.8 1.0 OD1 A:ASN137 4.4 15.5 1.0 CG A:GLU140 4.4 9.6 1.0 N A:VAL136 4.5 10.8 1.0 C A:ASP129 4.5 15.7 1.0 CA A:GLN135 4.5 13.7 1.0 CB A:ASP131 4.5 14.6 1.0 N A:GLY132 4.6 16.9 1.0 N A:THR130 4.6 11.7 1.0 CA A:ASP133 4.7 18.4 1.0 CA A:ASP131 4.7 13.6 1.0 CG A:ASN137 4.8 11.8 1.0 N A:GLY134 4.8 15.3 1.0 C A:VAL136 4.8 9.8 1.0 C A:ASP131 4.8 14.1 1.0 CB A:ASN137 4.9 8.5 1.0 O A:ASP129 5.0 17.8 1.0 C A:ASP133 5.0 17.8 1.0

B.G.Han, M.Han, H.Sui, P.Yaswen, P.J.Walian, B.K.Jap. Crystal Structure of Human Calmodulin-Like Protein: Insights Into Its Functional Role. Febs Lett. V. 521 24 2002.
ISSN: ISSN 0014-5793
PubMed: 12067719
DOI: 10.1016/S0014-5793(02)02780-1