Calcium in PDB 1gnh: Human C-Reactive Protein

The structure of Human C-Reactive Protein, PDB code: 1gnh was solved by A.K.Shrive, G.M.T.Cheetham, D.Holden, D.A.Myles, W.G.Turnell, J.E.Volanakis, M.B.Pepys, A.C.Bloomer, T.J.Greenhough, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	12.00 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	101.060, 154.250, 242.930, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 27.3

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 16;

Binding sites:

The binding sites of Calcium atom in the Human C-Reactive Protein (pdb code 1gnh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 16 binding sites of Calcium where determined in the Human C-Reactive Protein, PDB code: 1gnh:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca501 b:81.0 occ:1.00 OD1 A:ASP140 1.8 57.4 1.0 OE1 A:GLU138 2.4 28.6 1.0 O A:GLN139 2.6 34.9 1.0 OE2 A:GLU138 2.8 37.0 1.0 CD A:GLU138 3.0 31.0 1.0 ND2 A:ASN61 3.0 40.5 1.0 CG A:ASP140 3.0 55.7 1.0 OD1 A:ASN61 3.0 35.0 1.0 OD2 A:ASP60 3.2 36.2 1.0 CG A:ASN61 3.4 26.2 1.0 C A:GLN139 3.7 33.5 1.0 CA A:ASP140 3.8 45.1 1.0 OD2 A:ASP140 3.8 55.0 1.0 CB A:ASP140 3.9 42.8 1.0 N A:ASP140 4.1 39.5 1.0 CA A:CA502 4.2 79.9 1.0 CG A:ASP60 4.4 37.0 1.0 CG A:GLU138 4.5 21.2 1.0 CA A:GLN139 4.9 25.3 1.0 CB A:ASN61 4.9 8.5 1.0 N A:GLN139 5.0 22.8 1.0

Calcium binding site 2 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca502 b:79.9 occ:1.00 OE1 A:GLN150 2.1 27.1 1.0 OD2 A:ASP140 2.4 55.0 1.0 OE1 A:GLU138 2.5 28.6 1.0 CD A:GLN150 3.2 21.8 1.0 CG A:ASP140 3.3 55.7 1.0 OD1 A:ASP140 3.4 57.4 1.0 CD A:GLU138 3.6 31.0 1.0 NE2 A:GLN150 3.8 29.5 1.0 CB A:GLU147 3.8 40.8 1.0 CG A:GLU138 4.0 21.2 1.0 CB A:GLU138 4.2 8.5 1.0 CA A:CA501 4.2 81.0 1.0 CG A:GLN150 4.3 9.2 1.0 CG A:GLU147 4.4 50.4 1.0 O A:GLU138 4.5 23.2 1.0 OE2 A:GLU138 4.6 37.0 1.0 CB A:ASP140 4.7 42.8 1.0 CB A:GLN150 4.9 16.1 1.0 N A:GLU147 4.9 44.8 1.0 CA A:GLU147 5.0 45.0 1.0

Calcium binding site 3 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca501 b:84.7 occ:1.00 OE1 B:GLU138 1.8 46.9 1.0 CD B:GLU138 2.2 31.6 1.0 OE2 B:GLU138 2.3 40.4 1.0 OD1 B:ASP140 2.6 55.6 1.0 OD1 B:ASN61 3.1 44.0 1.0 ND2 B:ASN61 3.2 47.3 1.0 O B:GLN139 3.2 30.1 1.0 CG B:ASN61 3.5 41.3 1.0 CG B:GLU138 3.6 27.9 1.0 CA B:CA502 3.7 76.5 1.0 CG B:ASP140 3.7 52.6 1.0 C B:GLN139 4.2 33.7 1.0 OD2 B:ASP140 4.2 56.0 1.0 OD2 B:ASP60 4.4 46.4 1.0 OE1 B:GLN150 4.6 36.8 1.0 CD1 B:LEU64 4.7 9.0 1.0 CB B:GLU138 4.7 19.2 1.0 CA B:ASP140 4.8 46.7 1.0 CB B:ASP140 4.9 40.6 1.0 N B:ASP140 4.9 39.4 1.0 N B:GLN139 4.9 27.0 1.0 C B:GLU138 4.9 23.7 1.0

Calcium binding site 4 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca502 b:76.5 occ:1.00 OD2 B:ASP140 2.1 56.0 1.0 OE1 B:GLU138 2.2 46.9 1.0 OE1 B:GLN150 2.3 36.8 1.0 CG B:ASP140 2.9 52.6 1.0 OD1 B:ASP140 3.0 55.6 1.0 CD B:GLU138 3.2 31.6 1.0 CD B:GLN150 3.5 41.1 1.0 CA B:CA501 3.7 84.7 1.0 CG B:GLU138 3.7 27.9 1.0 CB B:GLU138 3.8 19.2 1.0 O B:GLU138 4.0 26.4 1.0 NE2 B:GLN150 4.2 51.5 1.0 OE2 B:GLU138 4.2 40.4 1.0 CB B:ASP140 4.3 40.6 1.0 CB B:GLU147 4.3 52.8 1.0 CG B:GLN150 4.5 30.8 1.0 C B:GLU138 4.5 23.7 1.0 N B:GLU147 4.7 49.5 1.0 O B:ASN145 4.8 47.3 1.0 CA B:GLU138 4.9 23.3 1.0 O B:GLN139 4.9 30.1 1.0 CB B:GLN150 5.0 25.8 1.0

Calcium binding site 5 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca501 b:77.8 occ:1.00 OD1 C:ASP140 2.0 47.0 1.0 O C:GLN139 2.4 38.7 1.0 OE1 C:GLU138 2.4 32.3 1.0 OE2 C:GLU138 2.5 43.2 1.0 OD1 C:ASN61 2.7 37.4 1.0 CD C:GLU138 2.7 39.9 1.0 ND2 C:ASN61 3.1 37.2 1.0 CG C:ASP140 3.1 47.4 1.0 CG C:ASN61 3.3 30.3 1.0 OD2 C:ASP60 3.3 35.2 1.0 C C:GLN139 3.4 37.6 1.0 CA C:ASP140 3.8 43.9 1.0 CA C:CA502 3.8 76.5 1.0 OD2 C:ASP140 3.9 43.0 1.0 N C:ASP140 4.0 41.2 1.0 CB C:ASP140 4.0 42.8 1.0 CG C:GLU138 4.3 34.9 1.0 CG C:ASP60 4.4 39.3 1.0 CA C:GLN139 4.6 25.2 1.0 N C:GLN139 4.7 22.2 1.0 CB C:ASN61 4.8 8.5 1.0 C C:GLU138 4.9 26.0 1.0

Calcium binding site 6 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca502 b:76.5 occ:1.00 OE1 C:GLU147 2.0 45.3 1.0 OD2 C:ASP140 2.0 43.0 1.0 OE1 C:GLU138 2.0 32.3 1.0 OE1 C:GLN150 2.3 27.8 1.0 CG C:ASP140 2.8 47.4 1.0 OD1 C:ASP140 2.9 47.0 1.0 CD C:GLU138 3.1 39.9 1.0 CD C:GLU147 3.1 51.9 1.0 CD C:GLN150 3.5 34.2 1.0 CG C:GLU138 3.6 34.9 1.0 CG C:GLU147 3.7 44.8 1.0 CB C:GLU138 3.8 22.3 1.0 CA C:CA501 3.8 77.8 1.0 O C:GLU138 4.0 30.8 1.0 OE2 C:GLU138 4.1 43.2 1.0 CB C:GLU147 4.1 34.7 1.0 OE2 C:GLU147 4.2 52.5 1.0 CB C:ASP140 4.2 42.8 1.0 NE2 C:GLN150 4.2 47.6 1.0 C C:GLU138 4.5 26.0 1.0 CG C:GLN150 4.6 18.9 1.0 O C:GLN139 4.8 38.7 1.0 N C:GLU147 4.8 43.2 1.0 O C:ASN145 4.8 44.3 1.0 CA C:GLU138 4.8 24.6 1.0 C C:GLN139 5.0 37.6 1.0

Calcium binding site 7 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca501 b:78.5 occ:1.00 OD1 E:ASP140 1.9 48.5 1.0 O E:GLN139 2.5 37.8 1.0 OD2 E:ASP60 2.7 41.6 1.0 ND2 E:ASN61 2.8 42.0 1.0 OD1 E:ASN61 2.8 43.7 1.0 OE1 E:GLU138 2.9 49.4 1.0 OE2 E:GLU138 3.0 32.8 1.0 CG E:ASP140 3.1 48.1 1.0 CG E:ASN61 3.2 35.3 1.0 CD E:GLU138 3.3 42.6 1.0 C E:GLN139 3.6 35.1 1.0 CA E:ASP140 3.6 42.8 1.0 CB E:ASP140 3.9 44.4 1.0 CG E:ASP60 3.9 45.9 1.0 N E:ASP140 4.0 38.5 1.0 OD2 E:ASP140 4.0 46.7 1.0 CA E:CA502 4.1 74.5 1.0 CB E:ASP60 4.6 38.7 1.0 CB E:ASN61 4.6 8.5 1.0 OD1 E:ASP60 4.8 50.1 1.0 C E:ASP140 4.8 45.5 1.0 CG E:GLU138 4.9 34.5 1.0 CA E:GLN139 4.9 23.3 1.0 O E:ASP60 5.0 26.9 1.0 C E:ASP60 5.0 25.9 1.0

Calcium binding site 8 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca502 b:74.5 occ:1.00 OE1 E:GLU138 2.1 49.4 1.0 OE1 E:GLN150 2.2 34.5 1.0 OD2 E:ASP140 2.3 46.7 1.0 OD1 E:ASP140 2.9 48.5 1.0 CG E:ASP140 3.0 48.1 1.0 CD E:GLU138 3.3 42.6 1.0 CD E:GLN150 3.3 40.8 1.0 OE2 E:GLU147 3.8 73.7 1.0 CG E:GLU138 3.8 34.5 1.0 NE2 E:GLN150 3.9 54.1 1.0 CD E:GLU147 4.1 76.7 1.0 CB E:GLU138 4.1 19.7 1.0 CA E:CA501 4.1 78.5 1.0 CB E:GLU147 4.2 67.2 1.0 OE2 E:GLU138 4.3 32.8 1.0 OE1 E:GLU147 4.3 60.4 1.0 O E:GLU138 4.4 25.0 1.0 CB E:ASP140 4.4 44.4 1.0 CG E:GLN150 4.6 26.8 1.0 CG E:GLU147 4.7 78.9 1.0 C E:GLU138 4.9 20.0 1.0 O E:GLN139 5.0 37.8 1.0

Calcium binding site 9 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca501 b:78.0 occ:1.00 OE1 F:GLU138 2.1 45.3 1.0 OD1 F:ASP140 2.5 46.1 1.0 CD F:GLU138 2.8 42.7 1.0 OD1 F:ASN61 2.9 43.7 1.0 OE2 F:GLU138 3.0 34.0 1.0 ND2 F:ASN61 3.5 34.9 1.0 CG F:ASN61 3.6 34.4 1.0 CA F:CA502 3.6 33.9 1.0 CG F:ASP140 3.6 47.1 1.0 O F:GLN139 3.6 39.1 1.0 OD2 F:ASP60 4.1 39.0 1.0 CG F:GLU138 4.2 38.1 1.0 OD2 F:ASP140 4.2 49.5 1.0 C F:GLN139 4.6 40.3 1.0 OE1 F:GLN150 4.7 19.4 1.0 CB F:ASP140 4.8 46.1 1.0 CA F:ASP140 4.9 47.0 1.0

Calcium binding site 10 out of 16 in the Human C-Reactive Protein


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Human C-Reactive Protein within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca502 b:33.9 occ:1.00 OE1 F:GLU138 2.1 45.3 1.0 OD2 F:ASP140 2.2 49.5 1.0 OE1 F:GLN150 2.2 19.4 1.0 OE2 F:GLU147 2.8 61.1 1.0 CD F:GLU147 2.9 74.0 1.0 CG F:ASP140 2.9 47.1 1.0 OD1 F:ASP140 3.0 46.1 1.0 CD F:GLU138 3.0 42.7 1.0 OE1 F:GLU147 3.3 81.2 1.0 CD F:GLN150 3.4 22.5 1.0 CG F:GLU147 3.4 69.7 1.0 CG F:GLU138 3.5 38.1 1.0 CA F:CA501 3.6 78.0 1.0 CB F:GLU138 3.7 20.9 1.0 O F:GLU138 3.9 27.7 1.0 CB F:GLU147 3.9 58.3 1.0 OE2 F:GLU138 4.1 34.0 1.0 NE2 F:GLN150 4.2 38.2 1.0 CB F:ASP140 4.3 46.1 1.0 C F:GLU138 4.5 26.0 1.0 CG F:GLN150 4.5 26.9 1.0 N F:GLU147 4.7 47.6 1.0 CA F:GLU138 4.7 22.4 1.0 O F:GLN139 4.8 39.1 1.0 O F:ASN145 4.8 45.0 1.0 CB F:GLN150 4.9 23.9 1.0 CA F:GLU147 5.0 50.9 1.0

A.K.Shrive, G.M.Cheetham, D.Holden, D.A.Myles, W.G.Turnell, J.E.Volanakis, M.B.Pepys, A.C.Bloomer, T.J.Greenhough. Three Dimensional Structure of Human C-Reactive Protein. Nat.Struct.Biol. V. 3 346 1996.
ISSN: ISSN 1072-8368
PubMed: 8599761
DOI: 10.1038/NSB0496-346