Calcium in PDB 1h1v: Gelsolin G4-G6/Actin Complex

The structure of Gelsolin G4-G6/Actin Complex, PDB code: 1h1v was solved by H.Choe, L.D.Burtnick, M.Mejillano, H.L.Yin, R.C.Robinson, S.Choe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.73 / 2.99
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.350, 113.450, 159.350, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 26.8

The binding sites of Calcium atom in the Gelsolin G4-G6/Actin Complex (pdb code 1h1v). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Gelsolin G4-G6/Actin Complex, PDB code: 1h1v:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the Gelsolin G4-G6/Actin Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Gelsolin G4-G6/Actin Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1376 b:28.4 occ:1.00 O2G A:ATP1377 2.2 3.7 1.0 O1B A:ATP1377 2.6 2.4 1.0 OE1 A:GLN137 3.2 13.2 1.0 PG A:ATP1377 3.6 4.8 1.0 PB A:ATP1377 3.9 3.4 1.0 OD2 A:ASP11 3.9 11.7 1.0 CD A:GLN137 4.0 11.5 1.0 O1G A:ATP1377 4.0 2.6 1.0 CA A:GLY13 4.2 11.6 1.0 O3B A:ATP1377 4.2 3.7 1.0 OD1 A:ASP11 4.4 13.8 1.0 OD1 A:ASP154 4.5 13.4 1.0 CG A:ASP11 4.6 12.3 1.0 CG A:GLN137 4.7 10.3 1.0 NE2 A:GLN137 4.7 8.8 1.0 NZ A:LYS18 4.7 6.2 1.0 O2B A:ATP1377 4.8 6.2 1.0 O2A A:ATP1377 4.8 3.8 1.0 O A:HOH2081 4.8 21.4 1.0 O3G A:ATP1377 4.9 4.1 1.0 OD2 A:ASP154 4.9 9.9 1.0 O A:HOH2182 5.0 28.9 1.0 N A:GLY13 5.0 11.6 1.0

Calcium binding site 2 out of 5 in the Gelsolin G4-G6/Actin Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Gelsolin G4-G6/Actin Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Ca1743 b:16.0 occ:1.00 O A:HOH2087 2.5 18.8 1.0 O G:PRO494 2.5 16.6 1.0 OD2 G:ASP487 2.5 14.9 1.0 OE1 A:GLU167 2.5 14.4 1.0 OD1 G:ASP487 2.6 17.5 1.0 CG G:ASP487 3.0 18.5 1.0 O G:GLY492 3.0 22.9 1.0 C G:GLY492 3.3 22.8 1.0 CD A:GLU167 3.7 14.9 1.0 C G:PRO494 3.7 16.9 1.0 CA G:GLY492 3.8 23.8 1.0 N G:THR493 4.0 21.8 1.0 N G:PRO494 4.2 18.1 1.0 C G:THR493 4.2 19.6 1.0 OE2 A:GLU167 4.3 15.7 1.0 CA G:THR493 4.5 21.0 1.0 CB G:ASP487 4.5 20.5 1.0 O G:THR493 4.5 19.0 1.0 CD G:PRO494 4.5 17.8 1.0 CA G:PRO494 4.6 17.7 1.0 CG G:PRO494 4.6 17.9 1.0 N G:VAL495 4.7 15.9 1.0 CG A:GLU167 4.7 13.7 1.0 CB A:GLU167 4.8 12.2 1.0 CA G:VAL495 4.8 15.4 1.0 O A:HOH2084 4.8 30.5 1.0

Calcium binding site 3 out of 5 in the Gelsolin G4-G6/Actin Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Gelsolin G4-G6/Actin Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Ca1744 b:23.5 occ:1.00 OD1 G:ASP445 2.1 13.3 1.0 OE1 G:GLU475 2.3 19.9 1.0 O G:GLY444 2.5 15.7 1.0 OE2 G:GLU475 2.9 21.1 1.0 CD G:GLU475 2.9 20.1 1.0 O G:THR524 3.2 48.2 1.0 CG G:ASP445 3.3 15.3 1.0 C G:THR524 3.6 47.9 1.0 C G:GLY444 3.7 16.0 1.0 CA G:SER525 3.8 51.6 1.0 N G:SER525 3.9 50.0 1.0 OD2 G:ASP445 4.0 15.6 1.0 CA G:ASP445 4.3 15.6 1.0 N G:THR524 4.3 44.8 1.0 CG G:GLU475 4.4 18.8 1.0 CB G:ASP445 4.4 15.4 1.0 CB G:SER525 4.4 51.8 1.0 N G:ASP445 4.4 15.7 1.0 C G:GLY523 4.5 42.7 1.0 CA G:THR524 4.6 46.5 1.0 OG1 G:THR472 4.6 15.8 1.0 CA G:GLY444 4.7 16.2 1.0 O G:GLY523 4.8 42.5 1.0 O G:HOH2068 4.9 20.5 1.0 CA G:SER471 5.0 15.3 1.0 CA G:GLY523 5.0 41.2 1.0

Calcium binding site 4 out of 5 in the Gelsolin G4-G6/Actin Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Gelsolin G4-G6/Actin Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Ca1745 b:29.2 occ:1.00 OD1 G:ASN564 2.4 33.4 1.0 O G:ASN564 2.4 33.4 1.0 OE2 G:GLU587 2.5 50.7 1.0 OE1 G:GLU587 2.5 51.6 1.0 OD1 G:ASP565 2.5 27.1 1.0 CD G:GLU587 2.8 51.2 1.0 CG G:ASN564 3.4 32.6 1.0 C G:ASN564 3.5 33.6 1.0 CG G:ASP565 3.7 31.8 1.0 CA G:ASP565 4.2 33.8 1.0 ND2 G:ASN564 4.2 31.3 1.0 CG G:GLU587 4.3 50.7 1.0 N G:ASP565 4.3 33.6 1.0 CB G:ASN564 4.4 33.2 1.0 CG G:ARG542 4.4 36.4 1.0 O G:ALA543 4.4 35.3 1.0 CA G:ASN564 4.5 33.5 1.0 CB G:ASP565 4.5 33.6 1.0 OD2 G:ASP565 4.6 30.8 1.0 O G:GLY582 4.7 42.4 1.0 N G:SER584 4.8 44.2 1.0 CA G:ALA583 4.8 43.2 1.0 N G:ALA543 4.8 34.9 1.0 CE G:MET635 4.9 74.1 1.0 OG G:SER584 5.0 45.2 1.0

Calcium binding site 5 out of 5 in the Gelsolin G4-G6/Actin Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Gelsolin G4-G6/Actin Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Ca1746 b:15.3 occ:1.00 OD2 G:ASP670 2.2 16.6 1.0 OE2 G:GLU692 2.4 11.9 1.0 O G:ASP669 2.4 20.4 1.0 OE1 G:GLU692 2.7 15.8 1.0 CD G:GLU692 2.8 15.8 1.0 CG G:ASP670 3.4 17.9 1.0 C G:ASP669 3.4 20.4 1.0 CA G:ASP670 4.0 18.5 1.0 OG G:SER646 4.0 12.5 1.0 N G:ASP670 4.1 19.4 1.0 CB G:ASP670 4.2 18.4 1.0 ND2 G:ASN647 4.3 20.8 1.0 CB G:ASP669 4.3 22.3 1.0 OD1 G:ASP670 4.3 16.6 1.0 CG G:GLU692 4.3 17.6 1.0 CA G:ASP669 4.4 21.3 1.0 OD2 G:ASP669 4.5 30.5 1.0 O G:HOH2023 4.6 19.7 1.0 CA G:SER688 4.7 20.1 1.0 CG G:ASP669 4.8 25.5 1.0 CB G:SER646 4.8 13.8 1.0 N G:GLN689 4.8 21.5 1.0 O G:ASP687 4.9 17.7 1.0 CB G:LYS648 4.9 14.8 1.0 N G:ASN647 4.9 13.8 1.0 CB G:GLN689 4.9 21.7 1.0 CA G:SER646 5.0 13.8 1.0

H.Choe, L.D.Burtnick, M.Mejillano, H.L.Yin, R.C.Robinson, S.Choe. The Calcium Activation of Gelsolin:Insights From the 3A Structure of the G4-G6/Actin Complex J.Mol.Biol. V. 324 691 2002.
ISSN: ISSN 0022-2836
PubMed: 12460571
DOI: 10.1016/S0022-2836(02)01131-2