Calcium in PDB 1h4w: Structure of Human Trypsin IV (Brain Trypsin)

All present enzymatic activity of Structure of Human Trypsin IV (Brain Trypsin):
3.4.21.4;

The structure of Structure of Human Trypsin IV (Brain Trypsin), PDB code: 1h4w was solved by G.Katona, G.I.Berglund, J.Hajdu, L.Graf, L.Szilagyi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.70 / 1.70
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	56.683, 56.683, 143.210, 90.00, 90.00, 90.00
R / Rfree (%)	18.8 / 20.3

The binding sites of Calcium atom in the Structure of Human Trypsin IV (Brain Trypsin) (pdb code 1h4w). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of Human Trypsin IV (Brain Trypsin), PDB code: 1h4w:

Calcium binding site 1 out of 1 in the Structure of Human Trypsin IV (Brain Trypsin)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human Trypsin IV (Brain Trypsin) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca260 b:17.3 occ:1.00 OE2 A:GLU80 2.3 19.6 1.0 O A:VAL75 2.3 21.6 1.0 OE1 A:GLU70 2.3 16.7 1.0 O A:ASN72 2.3 16.9 1.0 O A:HOH2035 2.4 19.7 1.0 OE1 A:GLU77 2.5 23.0 1.0 CD A:GLU80 3.3 21.0 1.0 CD A:GLU70 3.3 16.9 1.0 CD A:GLU77 3.4 26.0 1.0 C A:VAL75 3.4 23.7 1.0 C A:ASN72 3.5 16.7 1.0 CG A:GLU80 3.7 21.1 1.0 OE2 A:GLU70 3.7 18.7 1.0 CG A:GLU77 3.9 25.4 1.0 N A:GLU77 4.1 23.4 1.0 CA A:LEU76 4.2 24.5 1.0 N A:LEU76 4.2 23.0 1.0 N A:VAL75 4.3 21.8 1.0 N A:ASN72 4.3 16.2 1.0 CA A:ILE73 4.3 19.4 1.0 N A:ILE73 4.3 17.7 1.0 OE2 A:GLU77 4.4 25.7 1.0 CA A:VAL75 4.4 23.7 1.0 CA A:ASN72 4.4 16.4 1.0 OE1 A:GLU80 4.4 22.8 1.0 CB A:GLU77 4.5 25.6 1.0 C A:LEU76 4.5 24.6 1.0 C A:ILE73 4.6 19.9 1.0 CG A:GLU70 4.6 16.7 1.0 O A:HOH2032 4.6 33.1 1.0 N A:HIS71 4.7 16.3 1.0 CB A:ASN72 4.7 17.2 1.0 O A:HOH2024 4.7 31.2 1.0 N A:LYS74 4.9 21.1 1.0 CA A:GLU70 4.9 14.0 1.0 CB A:GLU70 4.9 14.2 1.0 CA A:GLU77 4.9 24.8 1.0 O A:ILE73 5.0 21.1 1.0

G.Katona, G.I.Berglund, J.Hajdu, L.Graf, L.Szilagyi. Crystal Structure Reveals Basis For the Inhibitor Resistance of Human Brain Trypsin. J. Mol. Biol. V. 315 1209 2002.
ISSN: ISSN 0022-2836
PubMed: 11827488
DOI: 10.1006/JMBI.2001.5305