Calcium in PDB 1h6g: Alpha-Catenin M-Domain

The structure of Alpha-Catenin M-Domain, PDB code: 1h6g was solved by J.Yang, P.Dokurno, N.K.Tonks, D.Barford, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.74 / 2.2
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.863, 85.703, 75.481, 90.00, 100.47, 90.00
R / Rfree (%)	19.3 / 25.7

The structure of Alpha-Catenin M-Domain also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Calcium atom in the Alpha-Catenin M-Domain (pdb code 1h6g). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Alpha-Catenin M-Domain, PDB code: 1h6g:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Alpha-Catenin M-Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Alpha-Catenin M-Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1632 b:84.0 occ:1.00 O A:HOH2073 2.4 56.6 1.0 CB A:ASP500 3.7 42.9 1.0 OD2 A:ASP510 3.8 47.3 1.0 O A:HOH2084 3.8 66.6 1.0 CG A:ASP500 4.0 46.2 1.0 O A:HOH2082 4.0 75.1 1.0 OD1 A:ASP504 4.1 47.1 1.0 O A:HOH2083 4.1 45.0 1.0 OD1 A:ASP500 4.4 49.7 1.0 OD2 A:ASP504 4.4 50.2 1.0 OD2 A:ASP500 4.4 50.9 1.0 O A:ASP500 4.5 35.9 1.0 CG A:ASP510 4.5 45.7 1.0 CA A:ASP500 4.5 38.4 1.0 CG A:ASP504 4.7 47.9 1.0 O A:HOH2077 4.8 49.5 1.0 C A:ASP500 4.9 37.4 1.0 OD2 A:ASP503 5.0 52.7 1.0

Calcium binding site 2 out of 2 in the Alpha-Catenin M-Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Alpha-Catenin M-Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1632 b:94.9 occ:1.00 O A:HOH2184 2.4 71.2 1.0 OE1 B:GLU521 3.3 48.0 0.8 O B:HOH2086 3.6 63.3 1.0 CD B:GLU521 4.2 46.2 0.8 CB B:ASN517 4.4 28.1 1.0 CE1 B:HIS518 4.4 44.5 1.0 ND1 B:HIS518 4.5 41.3 1.0 CG2 A:ILE612 4.6 38.1 1.0 C B:ASN517 4.8 28.3 1.0 OE2 B:GLU521 4.8 48.6 0.8 NE2 B:HIS518 4.8 45.0 1.0 N B:HIS518 4.9 30.5 1.0 O B:ASN517 5.0 30.4 1.0 CG B:GLU521 5.0 45.2 1.0

J.Yang, P.Dokurno, N.K.Tonks, D.Barford. Crystal Structure of the M-Fragment of Alpha-Catenin: Implications For Modulation of Cell Adhesion. Embo J. V. 20 3645 2001.
ISSN: ISSN 0261-4189
PubMed: 11447106
DOI: 10.1093/EMBOJ/20.14.3645