Calcium in PDB 1hfx: Alpha-Lactalbumin

All present enzymatic activity of Alpha-Lactalbumin:
2.4.1.22;

The structure of Alpha-Lactalbumin, PDB code: 1hfx was solved by A.C.W.Pike, K.Brew, K.R.Acharya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.590, 64.870, 49.000, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / n/a

The binding sites of Calcium atom in the Alpha-Lactalbumin (pdb code 1hfx). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Alpha-Lactalbumin, PDB code: 1hfx:

Calcium binding site 1 out of 1 in the Alpha-Lactalbumin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Alpha-Lactalbumin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca124 b:8.3 occ:1.00 O A:ASP84 2.2 10.2 1.0 O A:LYS79 2.2 10.8 1.0 O A:HOH131 2.3 8.6 1.0 OD1 A:ASP88 2.3 10.8 1.0 OD1 A:ASP82 2.4 12.1 1.0 OD1 A:ASP87 2.4 10.1 1.0 O A:HOH144 2.4 21.8 1.0 C A:ASP84 3.4 10.2 1.0 CG A:ASP82 3.4 13.7 1.0 CG A:ASP87 3.5 10.0 1.0 C A:LYS79 3.5 7.2 1.0 CG A:ASP88 3.5 10.2 1.0 OD2 A:ASP82 3.7 12.5 1.0 OD2 A:ASP87 3.8 13.9 1.0 OD2 A:ASP88 4.0 13.3 1.0 CA A:LEU80 4.2 8.5 1.0 CA A:ASP84 4.2 11.6 1.0 N A:LEU80 4.3 9.2 1.0 N A:LEU85 4.3 2.7 1.0 N A:ASP84 4.3 14.9 1.0 CA A:LEU85 4.4 3.4 1.0 CB A:ASP84 4.4 9.6 1.0 O A:ASP82 4.4 12.1 1.0 N A:ASP88 4.4 6.5 1.0 CA A:LYS79 4.5 7.0 1.0 N A:ASP82 4.6 12.0 1.0 C A:ASP82 4.7 12.8 1.0 C A:LEU80 4.7 9.9 1.0 CB A:ASP88 4.7 9.3 1.0 CB A:ASP82 4.7 14.0 1.0 C A:LEU85 4.8 2.9 1.0 N A:ASP87 4.8 8.1 1.0 CB A:ASP87 4.8 5.4 1.0 CA A:ASP82 4.9 13.0 1.0 CB A:LYS79 4.9 10.4 1.0 N A:LEU81 4.9 7.8 1.0 O A:HOH194 5.0 26.7 1.0 N A:THR86 5.0 7.1 1.0

A.C.Pike, K.Brew, K.R.Acharya. Crystal Structures of Guinea-Pig, Goat and Bovine Alpha-Lactalbumin Highlight the Enhanced Conformational Flexibility of Regions That Are Significant For Its Action in Lactose Synthase. Structure V. 4 691 1996.
ISSN: ISSN 0969-2126
PubMed: 8805552
DOI: 10.1016/S0969-2126(96)00075-5