Calcium in PDB 1hov: Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020

All present enzymatic activity of Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020:
3.4.24.24;

The structure of Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020 also contains other interesting chemical elements:

Zinc

(Zn)

22 atoms

The binding sites of Calcium atom in the Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020 (pdb code 1hov). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020, PDB code: 1hov:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca167 b:9.1 occ:1.00 OE2 A:GLU103 2.5 0.0 1.0 O A:LYS79 2.5 0.0 1.0 O A:ASP80 2.6 0.0 1.0 O A:LEU82 2.6 0.0 1.0 O A:GLY78 2.6 0.0 1.0 OD2 A:ASP77 2.6 0.0 1.0 OD2 A:ASP100 2.7 0.0 1.0 CG A:ASP100 2.8 0.0 1.0 OD1 A:ASP100 2.9 0.0 1.0 OD1 A:ASP77 2.9 0.0 1.0 CG A:ASP77 3.1 0.0 1.0 OE1 A:GLU103 3.1 0.0 1.0 HG A:LEU82 3.1 0.0 1.0 CD A:GLU103 3.2 0.0 1.0 C A:GLY78 3.4 0.0 1.0 C A:LYS79 3.6 0.0 1.0 C A:ASP80 3.7 0.0 1.0 C A:LEU82 3.7 0.0 1.0 HD22 A:LEU83 3.8 0.0 1.0 HA2 A:GLY78 3.8 0.0 1.0 HA A:LEU83 3.9 0.0 1.0 CB A:ASP100 3.9 0.0 1.0 CA A:GLY78 4.0 0.0 1.0 N A:GLY78 4.0 0.0 1.0 HB2 A:ASP100 4.0 0.0 1.0 HB3 A:ASP100 4.0 0.0 1.0 H A:GLY78 4.0 0.0 1.0 HA A:ASP80 4.1 0.0 1.0 CG A:LEU82 4.2 0.0 1.0 N A:LYS79 4.2 0.0 1.0 CA A:ASP80 4.3 0.0 1.0 N A:LEU82 4.3 0.0 1.0 HD23 A:LEU83 4.4 0.0 1.0 N A:ASP80 4.4 0.0 1.0 HH2 A:TRP105 4.4 0.0 1.0 C A:GLY81 4.4 0.0 1.0 C A:ASP77 4.5 0.0 1.0 H A:LEU82 4.5 0.0 1.0 CA A:LEU82 4.5 0.0 1.0 CA A:LYS79 4.5 0.0 1.0 CD2 A:LEU83 4.6 0.0 1.0 CB A:ASP77 4.6 0.0 1.0 HD23 A:LEU82 4.6 0.0 1.0 CG A:GLU103 4.6 0.0 1.0 O A:GLY81 4.7 0.0 1.0 N A:GLY81 4.7 0.0 1.0 N A:LEU83 4.7 0.0 1.0 HA3 A:GLY81 4.7 0.0 1.0 CA A:LEU83 4.8 0.0 1.0 HD13 A:LEU82 4.8 0.0 1.0 CA A:GLY81 4.9 0.0 1.0 O A:ASP77 4.9 0.0 1.0 CB A:LEU82 4.9 0.0 1.0 HG2 A:GLU103 4.9 0.0 1.0 CD1 A:LEU82 4.9 0.0 1.0 HB2 A:ASP77 5.0 0.0 1.0 HD12 A:LEU82 5.0 0.0 1.0 CD2 A:LEU82 5.0 0.0 1.0

Calcium binding site 2 out of 2 in the Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Solution Structure of A Catalytic Domain of Mmp-2 Complexed with Sc-74020 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca168 b:8.1 occ:1.00 OD1 A:ASP96 2.4 0.0 1.0 O A:ASP60 2.5 0.0 1.0 O A:GLY92 2.5 0.0 1.0 O A:GLY94 2.5 0.0 1.0 HA3 A:GLY95 2.6 0.0 1.0 C A:GLY94 2.7 0.0 1.0 H A:ASP96 2.8 0.0 1.0 CG A:ASP96 2.8 0.0 1.0 N A:GLY95 2.8 0.0 1.0 HA A:ILE61 2.8 0.0 1.0 N A:ASP96 2.8 0.0 1.0 C A:GLY95 2.8 0.0 1.0 CA A:GLY95 2.9 0.0 1.0 OD2 A:ASP96 3.0 0.0 1.0 O A:VAL93 3.2 0.0 1.0 H A:MET62 3.2 0.0 1.0 C A:VAL93 3.3 0.0 1.0 C A:GLY92 3.4 0.0 1.0 H A:GLY95 3.5 0.0 1.0 N A:GLY94 3.5 0.0 1.0 O A:GLY95 3.6 0.0 1.0 C A:ASP60 3.6 0.0 1.0 CA A:GLY94 3.7 0.0 1.0 CA A:ASP96 3.8 0.0 1.0 CA A:ILE61 3.8 0.0 1.0 CB A:ASP96 3.9 0.0 1.0 HA A:ASP96 3.9 0.0 1.0 N A:MET62 4.0 0.0 1.0 HA2 A:GLY95 4.0 0.0 1.0 HG23 A:ILE61 4.0 0.0 1.0 CA A:VAL93 4.0 0.0 1.0 HA A:VAL93 4.1 0.0 1.0 H A:GLY94 4.1 0.0 1.0 N A:VAL93 4.1 0.0 1.0 N A:ILE61 4.2 0.0 1.0 HA2 A:GLY94 4.3 0.0 1.0 SD A:MET62 4.3 0.0 1.0 CA A:GLY92 4.3 0.0 1.0 HE1 A:TRP11 4.3 0.0 1.0 C A:ILE61 4.3 0.0 1.0 HA2 A:GLY92 4.4 0.0 1.0 H A:GLY92 4.4 0.0 1.0 HB2 A:MET62 4.4 0.0 1.0 N A:GLY92 4.4 0.0 1.0 HB2 A:ASP96 4.5 0.0 1.0 HA3 A:GLY94 4.5 0.0 1.0 HG3 A:MET62 4.5 0.0 1.0 HB3 A:ASP96 4.6 0.0 1.0 HA A:ASP60 4.7 0.0 1.0 CA A:ASP60 4.8 0.0 1.0 O A:GLY90 4.8 0.0 1.0 CG A:MET62 4.8 0.0 1.0 CG2 A:ILE61 4.8 0.0 1.0 H A:VAL93 4.9 0.0 1.0 CB A:ILE61 5.0 0.0 1.0 O A:ALA59 5.0 0.0 1.0 CB A:MET62 5.0 0.0 1.0

Y.Feng, J.J.Likos, L.Zhu, H.Woodward, G.Munie, J.J.Mcdonald, A.M.Stevens, C.P.Howard, G.A.De Crescenzo, D.Welsch, H.-S.Shieh, W.C.Stallings. Solution Structure and Backbone Dynamics of the Catalytic Domain of Matrix Metalloproteinase-2 Complexed with A Hydroxamic Acid Inhibitor Biochim.Biophys.Acta V.1598 10 2002.
ISSN: ISSN 0006-3002
PubMed: 12147339
DOI: 10.1016/S0167-4838(02)00307-2