Calcium in PDB 1hoz: Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax

All present enzymatic activity of Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax:
3.2.2.1;

The structure of Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax, PDB code: 1hoz was solved by W.Versees, K.Decanniere, R.Pelle, J.Depoorter, D.W.Parkin, J.Steyaert, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	52.090, 74.000, 82.000, 90.00, 104.56, 90.00
R / Rfree (%)	18.6 / 21

The binding sites of Calcium atom in the Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax (pdb code 1hoz). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax, PDB code: 1hoz:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca328 b:29.3 occ:1.00 O A:HOH1438 2.4 37.4 1.0 O A:THR137 2.4 28.9 1.0 OD2 A:ASP10 2.4 31.1 1.0 O A:HOH1376 2.4 35.4 1.0 OD2 A:ASP261 2.5 32.8 1.0 OD2 A:ASP15 2.5 28.4 1.0 OD1 A:ASP15 2.5 30.3 1.0 O1 A:GOL1267 2.7 38.4 1.0 CG A:ASP15 2.8 28.6 1.0 CG A:ASP261 3.5 35.9 1.0 CG A:ASP10 3.5 33.1 1.0 C A:THR137 3.5 28.7 1.0 OD1 A:ASP261 3.8 39.2 1.0 C1 A:GOL1267 3.9 46.9 1.0 OD1 A:ASP10 3.9 32.3 1.0 CA A:GLY138 4.2 32.0 1.0 N A:GLY138 4.3 29.2 1.0 CB A:ASP15 4.3 28.3 1.0 OD1 A:ASP14 4.3 48.1 1.0 CB A:THR137 4.4 29.6 1.0 OG1 A:THR137 4.5 29.1 1.0 CA A:THR137 4.5 29.2 1.0 OD1 A:ASN186 4.5 38.3 1.0 O2 A:GOL1267 4.6 49.6 1.0 ND2 A:ASN186 4.6 29.3 1.0 N A:ASP10 4.6 29.1 1.0 OD2 A:ASP14 4.6 50.0 1.0 CG A:ASP14 4.7 47.1 1.0 N A:ASP15 4.8 31.1 1.0 CB A:ASP10 4.8 30.5 1.0 CB A:ASP261 4.8 33.6 1.0 CB A:ASN12 4.8 32.5 1.0 CA A:ASP15 4.8 29.0 1.0 C2 A:GOL1267 4.8 48.0 1.0 N A:ASN12 5.0 31.1 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of An Inosine-Adenosine-Guanosine-Preferring Nucleoside Hydrolase From Trypanosoma Vivax within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca328 b:29.8 occ:1.00 OD2 B:ASP10 2.4 32.7 1.0 O B:THR137 2.4 32.5 1.0 O B:HOH1428 2.4 38.3 1.0 OD2 B:ASP261 2.5 30.9 1.0 O B:HOH1427 2.5 40.6 1.0 OD2 B:ASP15 2.5 31.1 1.0 OD1 B:ASP15 2.6 30.1 1.0 O B:HOH1304 2.6 33.3 1.0 CG B:ASP15 2.9 30.9 1.0 CG B:ASP261 3.4 34.5 1.0 CG B:ASP10 3.5 32.3 1.0 C B:THR137 3.5 31.0 1.0 OD1 B:ASP14 3.6 49.2 0.5 OD1 B:ASP261 3.7 37.1 1.0 OD1 B:ASP10 3.9 33.6 1.0 OD2 B:ASP14 4.2 48.9 0.5 CG B:ASP14 4.2 45.3 0.5 CA B:GLY138 4.3 30.4 1.0 N B:GLY138 4.3 29.5 1.0 CB B:ASP15 4.3 32.1 1.0 CB B:THR137 4.3 31.6 1.0 OG1 B:THR137 4.5 32.4 1.0 CA B:THR137 4.5 31.4 1.0 N B:ASP10 4.5 30.8 1.0 OD1 B:ASN186 4.6 34.5 1.0 ND2 B:ASN186 4.6 29.7 1.0 OD1 B:ASP40 4.7 50.1 1.0 CB B:ASP10 4.7 30.2 1.0 N B:ASP15 4.8 31.8 1.0 CB B:ASN12 4.8 36.3 0.5 CB B:ASP261 4.8 33.2 1.0 CB B:ASN12 4.8 34.4 0.5 CA B:ASP15 4.9 32.1 1.0 CB B:ASP40 4.9 48.0 1.0 CA B:ASP10 5.0 31.8 1.0

W.Versees, K.Decanniere, R.Pelle, J.Depoorter, E.Brosens, D.W.Parkin, J.Steyaert. Structure and Function of A Novel Purine Specific Nucleoside Hydrolase From Trypanosoma Vivax. J.Mol.Biol. V. 307 1363 2001.
ISSN: ISSN 0022-2836
PubMed: 11292348
DOI: 10.1006/JMBI.2001.4548