Calcium in PDB 1kli: Cofactor-and Substrate-Assisted Activation of Factor Viia

All present enzymatic activity of Cofactor-and Substrate-Assisted Activation of Factor Viia:
3.4.21.21;

The structure of Cofactor-and Substrate-Assisted Activation of Factor Viia, PDB code: 1kli was solved by K.Sichler, D.W.Banner, A.D'arcy, K.P.Hopfner, R.Huber, W.Bode, G.B.Kresse, E.Kopetzki, H.Brandstetter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.69
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	94.443, 94.443, 114.315, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 22.5

The binding sites of Calcium atom in the Cofactor-and Substrate-Assisted Activation of Factor Viia (pdb code 1kli). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cofactor-and Substrate-Assisted Activation of Factor Viia, PDB code: 1kli:

Calcium binding site 1 out of 1 in the Cofactor-and Substrate-Assisted Activation of Factor Viia


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cofactor-and Substrate-Assisted Activation of Factor Viia within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca900 b:20.5 occ:1.00 O H:GLU75 2.3 24.4 1.0 OE1 H:GLU70 2.4 16.4 1.0 O H:HOH551 2.4 20.6 1.0 OE1 H:GLU80 2.4 17.0 1.0 O H:ASP72 2.4 16.7 1.0 O H:HOH646 2.5 20.1 1.0 CD H:GLU70 3.3 17.2 1.0 C H:GLU75 3.4 23.6 1.0 C H:ASP72 3.5 15.6 1.0 CD H:GLU80 3.5 16.4 1.0 OE2 H:GLU70 3.6 19.4 1.0 CG H:GLU80 3.8 14.5 1.0 N H:ASP72 3.9 15.4 1.0 O H:HOH550 4.0 16.4 1.0 CA H:HIS76 4.1 22.6 1.0 N H:HIS76 4.2 22.1 1.0 CA H:ASP72 4.2 16.8 1.0 O H:HOH576 4.4 27.1 1.0 N H:LEU73 4.4 15.5 1.0 N H:HIS71 4.4 13.9 1.0 N H:GLU75 4.5 22.3 1.0 CA H:GLU75 4.5 23.6 1.0 CB H:ASP72 4.6 18.8 1.0 OE2 H:GLU80 4.6 16.6 1.0 CA H:LEU73 4.6 16.8 1.0 O H:HOH574 4.6 25.5 1.0 O H:HOH681 4.6 27.9 1.0 N H:ASP77 4.6 20.9 1.0 CG H:GLU70 4.7 15.7 1.0 CG H:GLU75 4.8 29.9 1.0 C H:HIS76 4.9 21.6 1.0 C H:HIS71 4.9 15.2 1.0 C H:LEU73 4.9 18.3 1.0

K.Sichler, D.W.Banner, A.D'arcy, K.P.Hopfner, R.Huber, W.Bode, G.B.Kresse, E.Kopetzki, H.Brandstetter. Crystal Structure of Uninhibited Factor Viia Link Its Cofactor and Substrate-Assisted Activation to Specific Interactions J.Mol.Biol. V. 322 591 2002.
ISSN: ISSN 0022-2836
PubMed: 12225752
DOI: 10.1016/S0022-2836(02)00747-7