Calcium in PDB 1ldt: Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin

All present enzymatic activity of Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin:
3.4.21.4;

The structure of Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin, PDB code: 1ldt was solved by M.T.Stubbs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 1.90
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.400, 63.400, 131.200, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / n/a

The binding sites of Calcium atom in the Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin (pdb code 1ldt). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin, PDB code: 1ldt:

Calcium binding site 1 out of 1 in the Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Complex of Leech-Derived Tryptase Inhibitor with Porcine Trypsin within 5.0Å range: probe atom residue distance (Å) B Occ T:Ca1007 b:18.0 occ:1.00 O T:HOH2053 2.2 25.9 1.0 O T:VAL75 2.2 20.3 1.0 O T:ASN72 2.3 21.2 1.0 OE1 T:GLU70 2.5 19.2 1.0 OE2 T:GLU80 2.7 21.5 1.0 OE1 T:GLU77 2.9 18.3 1.0 C T:VAL75 3.3 28.8 1.0 C T:ASN72 3.5 18.6 1.0 CD T:GLU70 3.6 23.1 1.0 CD T:GLU80 3.6 23.9 1.0 CD T:GLU77 3.8 32.6 1.0 OE2 T:GLU70 3.9 17.4 1.0 O T:HOH2054 4.0 46.6 1.0 CG T:GLU80 4.0 13.7 1.0 N T:LEU76 4.1 25.1 1.0 CA T:LEU76 4.1 12.7 1.0 N T:GLU77 4.1 15.6 1.0 N T:VAL75 4.1 18.1 1.0 CA T:ILE73 4.2 10.2 1.0 CG T:GLU77 4.2 26.7 1.0 N T:ILE73 4.3 9.7 1.0 CA T:VAL75 4.3 10.2 1.0 C T:ILE73 4.4 11.1 1.0 N T:ASN72 4.5 15.0 1.0 CA T:ASN72 4.5 12.2 1.0 C T:LEU76 4.6 11.4 1.0 OE1 T:GLU80 4.7 20.4 1.0 O T:ILE73 4.7 15.6 1.0 CB T:GLU77 4.7 18.1 1.0 N T:ASP74 4.7 16.7 1.0 CB T:ASN72 4.8 15.6 1.0 OE2 T:GLU77 4.9 29.6 1.0 N T:HIS71 4.9 15.3 1.0 CG T:GLU70 4.9 15.3 1.0 O T:HOH3005 5.0 30.5 1.0

M.T.Stubbs, R.Morenweiser, J.Sturzebecher, M.Bauer, W.Bode, R.Huber, G.P.Piechottka, G.Matschiner, C.P.Sommerhoff, H.Fritz, E.A.Auerswald. The Three-Dimensional Structure of Recombinant Leech-Derived Tryptase Inhibitor in Complex with Trypsin. Implications For the Structure of Human Mast Cell Tryptase and Its Inhibition. J.Biol.Chem. V. 272 19931 1997.
ISSN: ISSN 0021-9258
PubMed: 9242660
DOI: 10.1074/JBC.272.32.19931