Calcium in PDB 1lhu: Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol

The structure of Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol, PDB code: 1lhu was solved by I.Grishkovskaya, G.V.Avvakumov, G.L.Hammond, M.G.Catalano, Y.A.Muller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.82 / 1.80
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	103.638, 103.638, 84.492, 90.00, 90.00, 120.00
R / Rfree (%)	20.4 / 23.7

The binding sites of Calcium atom in the Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol (pdb code 1lhu). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol, PDB code: 1lhu:

Calcium binding site 1 out of 1 in the Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the N-Terminal Lg-Domain of Shbg in Complex with Estradiol within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca401 b:25.3 occ:1.00 O A:ALA160 2.3 25.0 1.0 O A:GLU52 2.3 20.5 1.0 O A:HOH447 2.4 33.6 1.0 O A:HOH429 2.4 30.0 1.0 OD2 A:ASP50 2.4 28.4 1.0 OD1 A:ASP50 2.4 29.2 1.0 O A:HOH416 2.6 32.0 1.0 CG A:ASP50 2.8 27.1 1.0 C A:GLU52 3.5 20.4 1.0 C A:ALA160 3.5 24.9 1.0 CA A:LEU161 4.2 26.7 1.0 CA A:GLU52 4.2 20.1 1.0 CB A:ASP50 4.3 26.3 1.0 N A:GLU52 4.3 20.7 1.0 N A:LEU161 4.3 24.4 1.0 O A:HOH493 4.4 49.3 1.0 CB A:GLU52 4.4 17.6 1.0 N A:GLY53 4.4 17.4 1.0 O A:VAL158 4.5 19.6 1.0 CA A:ALA160 4.5 24.9 1.0 CA A:GLY53 4.5 17.1 1.0 CB A:ALA160 4.6 25.5 1.0 N A:ASP162 4.7 28.7 1.0 CD1 A:LEU161 4.8 31.3 1.0 N A:ALA160 4.9 22.6 1.0

I.Grishkovskaya, G.V.Avvakumov, G.L.Hammond, M.Catalano, Y.A.Muller. Steroid Ligands Bind Human Sex Hormone-Binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem. V. 277 32086 2002.
ISSN: ISSN 0021-9258
PubMed: 12065592
DOI: 10.1074/JBC.M203999200