Calcium in PDB 1mu5: Structure of Topoisomerase Subunit

All present enzymatic activity of Structure of Topoisomerase Subunit:
5.99.1.3;

The structure of Structure of Topoisomerase Subunit, PDB code: 1mu5 was solved by K.D.Corbett, J.M.Berger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	94.091, 110.968, 54.544, 90.00, 90.00, 90.00
R / Rfree (%)	21.4 / 23.8

The binding sites of Calcium atom in the Structure of Topoisomerase Subunit (pdb code 1mu5). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Topoisomerase Subunit, PDB code: 1mu5:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Topoisomerase Subunit


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Topoisomerase Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1 b:48.1 occ:1.00 O A:HOH614 2.0 73.9 1.0 O A:HOH676 2.0 77.8 1.0 O A:HOH635 2.1 79.1 1.0 O A:HOH479 2.2 45.3 1.0 O A:ARG105 2.4 9.0 1.0 O A:HOH686 2.7 95.3 1.0 O A:HOH501 3.0 39.8 1.0 C A:ARG105 3.5 9.9 1.0 OD1 A:ASN42 3.8 12.7 1.0 CA A:GLY106 3.8 11.4 1.0 O A:HOH699 4.0 81.7 1.0 N A:GLY106 4.1 9.9 1.0 OE2 A:GLU38 4.3 15.0 1.0 CA A:ARG105 4.7 9.0 1.0 OD2 A:ASP45 4.7 12.1 1.0 OE1 A:GLU41 4.8 8.7 1.0 N A:ARG105 4.8 9.2 1.0 CB A:GLU41 4.9 3.9 1.0 C A:GLY106 4.9 11.9 1.0 OG1 A:THR104 4.9 12.6 1.0 O A:HOH496 5.0 32.9 1.0 O A:HOH484 5.0 35.6 1.0 CG A:ASN42 5.0 11.2 1.0

Calcium binding site 2 out of 2 in the Structure of Topoisomerase Subunit


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Topoisomerase Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca471 b:43.7 occ:1.00 O A:GLU393 2.3 11.1 1.0 O A:HOH530 2.5 44.8 1.0 O A:LEU395 2.5 9.9 1.0 O A:HOH625 2.6 72.9 1.0 O A:HOH588 2.7 53.5 1.0 O A:HOH628 2.8 72.9 1.0 C A:GLU393 3.4 11.4 1.0 C A:LEU395 3.5 11.2 1.0 C A:GLU394 4.0 11.6 1.0 O A:GLU394 4.1 11.2 1.0 N A:LEU395 4.2 11.1 1.0 CA A:ASP396 4.2 12.2 1.0 N A:ASP396 4.2 11.5 1.0 CA A:GLU393 4.3 11.9 1.0 N A:GLU394 4.3 11.6 1.0 O A:VAL392 4.4 8.4 1.0 CA A:GLU394 4.4 11.9 1.0 CA A:LEU395 4.5 11.9 1.0 CD1 A:TRP397 4.7 12.3 1.0 N A:TRP397 4.9 12.5 1.0

K.D.Corbett, J.M.Berger. Structure of the Topoisomerase VI-B Subunit: Implications For Type II Topoisomerase Mechanism and Evolution Embo J. V. 22 151 2003.
ISSN: ISSN 0261-4189
PubMed: 12505993
DOI: 10.1093/EMBOJ/CDG008