Calcium in PDB 1nph: Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions

The structure of Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions, PDB code: 1nph was solved by S.Kolappan, J.T.Gooch, A.G.Weeds, P.J.Mclaughlin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 3.00
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	122.520, 122.520, 82.723, 90.00, 90.00, 90.00
R / Rfree (%)	24.7 / 29.9

The binding sites of Calcium atom in the Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions (pdb code 1nph). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions, PDB code: 1nph:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca744 b:48.1 occ:1.00 OD1 A:ASN564 2.4 41.2 1.0 OE2 A:GLU587 2.4 56.8 1.0 O A:ASN564 2.4 41.7 1.0 OD1 A:ASP565 2.5 40.0 1.0 OE1 A:GLU587 2.6 57.2 1.0 CD A:GLU587 2.8 56.8 1.0 CG A:ASN564 3.3 38.1 1.0 C A:ASN564 3.4 42.4 1.0 CG A:ASP565 3.8 41.9 1.0 ND2 A:ASN564 3.8 37.1 1.0 CA A:ASP565 4.0 43.4 1.0 N A:ASP565 4.1 43.0 1.0 O A:GLY582 4.2 50.1 1.0 CG A:GLU587 4.2 56.6 1.0 CB A:ASN564 4.3 39.1 1.0 CA A:ASN564 4.4 40.9 1.0 CB A:ASP565 4.5 42.4 1.0 CA A:ALA583 4.6 52.2 1.0 N A:SER584 4.6 55.3 1.0 CG A:ARG542 4.7 43.7 1.0 C A:GLY582 4.7 50.9 1.0 OD2 A:ASP565 4.7 41.1 1.0 N A:ALA543 4.8 43.4 1.0 N A:ALA583 4.9 51.7 1.0

Calcium binding site 2 out of 2 in the Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca745 b:52.6 occ:1.00 O A:ASP669 2.3 36.2 1.0 OD2 A:ASP670 2.4 34.7 1.0 OE1 A:GLU692 2.4 39.5 1.0 OE2 A:GLU692 2.6 39.8 1.0 CD A:GLU692 2.8 38.9 1.0 C A:ASP669 3.5 35.9 1.0 CG A:ASP670 3.6 32.8 1.0 CA A:ASP670 4.1 30.6 1.0 OG A:SER646 4.2 30.8 1.0 N A:ASP670 4.3 33.4 1.0 CG A:GLU692 4.3 37.1 1.0 OD1 A:ASP670 4.4 32.2 1.0 CB A:ASP670 4.4 29.9 1.0 CB A:ASP669 4.5 39.6 1.0 CA A:ASP669 4.6 37.3 1.0 N A:GLN689 4.6 39.7 1.0 CA A:SER688 4.7 37.2 1.0 N A:ASN647 4.7 36.4 1.0 O A:ASN647 4.7 43.1 1.0 OE1 A:GLN689 4.7 56.0 1.0 CG A:GLN689 4.9 47.1 1.0 O A:ASP687 4.9 39.0 1.0

S.Kolappan, J.T.Gooch, A.G.Weeds, P.J.Mclaughlin. Gelsolin Domains 4-6 in Active, Actin-Free Conformation Identifies Sites of Regulatory Calcium Ions J.Mol.Biol. V. 329 85 2003.
ISSN: ISSN 0022-2836
PubMed: 12742020
DOI: 10.1016/S0022-2836(03)00383-8