Calcium in PDB 1p2p: Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2

All present enzymatic activity of Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2:
3.1.1.4;

The structure of Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2, PDB code: 1p2p was solved by B.W.Dijkstra, R.Renetseder, K.H.Kalk, W.G.J.Hol, J.Drenth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.60
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	69.820, 69.820, 67.660, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Calcium atom in the Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2 (pdb code 1p2p). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2, PDB code: 1p2p:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca125 b:20.8 occ:1.00 OD2 A:ASP49 2.0 9.6 1.0 OD1 A:ASP49 2.4 10.7 1.0 O A:GLY30 2.5 24.6 1.0 CG A:ASP49 2.6 9.2 1.0 O A:TYR28 2.6 11.5 1.0 O A:GLY32 2.7 24.6 1.0 N A:GLY32 3.6 28.2 1.0 C A:GLY32 3.6 24.7 1.0 C A:GLY30 3.7 24.1 1.0 C A:TYR28 3.7 10.6 1.0 O A:HOH130 3.9 30.3 1.0 CB A:ASP49 4.0 6.6 1.0 CA A:GLY32 4.1 26.0 1.0 CA A:TYR28 4.3 8.4 1.0 C A:LEU31 4.3 29.6 1.0 CA A:LEU31 4.3 29.1 1.0 N A:GLY30 4.4 17.5 1.0 N A:LEU31 4.5 27.6 1.0 CB A:TYR28 4.6 5.8 1.0 O A:CYS45 4.6 13.0 1.0 CD1 A:TYR28 4.8 1.0 1.0 N A:GLY33 4.8 22.4 1.0 CA A:GLY30 4.8 20.2 1.0 N A:CYS29 4.8 12.3 1.0 C A:CYS29 4.9 15.2 1.0 CA A:ASP49 5.0 6.3 1.0

Calcium binding site 2 out of 2 in the Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Angstroms Resolution and Comparison with Bovine Phospholipase A2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca126 b:20.1 occ:0.50 O A:SER72 2.4 5.6 1.0 OE1 A:GLU92 2.7 10.6 1.0 C A:SER72 3.5 7.0 1.0 N A:SER72 3.7 10.4 1.0 CD A:GLU92 3.8 8.8 1.0 CD A:GLU71 3.9 17.3 1.0 OE1 A:GLU71 4.0 19.5 1.0 CA A:SER72 4.0 6.9 1.0 CB A:SER72 4.1 6.1 1.0 CG A:GLU71 4.2 14.3 1.0 OE2 A:GLU92 4.3 12.5 1.0 OE2 A:GLU71 4.3 21.0 1.0 OG A:SER72 4.6 4.6 1.0 N A:TYR73 4.6 9.5 1.0 C A:GLU71 4.7 10.8 1.0 CB A:GLU92 4.8 3.7 1.0 CG A:GLU92 4.9 6.1 1.0 CA A:TYR73 5.0 9.1 1.0 CA A:GLU71 5.0 8.7 1.0

B.W.Dijkstra, R.Renetseder, K.H.Kalk, W.G.Hol, J.Drenth. Structure of Porcine Pancreatic Phospholipase A2 at 2.6 A Resolution and Comparison with Bovine Phospholipase A2. J.Mol.Biol. V. 168 163 1983.
ISSN: ISSN 0022-2836
PubMed: 6876174
DOI: 10.1016/S0022-2836(83)80328-3