Calcium in PDB 1pz7: Modulation of Agrin Function By Alternative Splicing and CA2+ Binding

The structure of Modulation of Agrin Function By Alternative Splicing and CA2+ Binding, PDB code: 1pz7 was solved by J.Stetefeld, A.T.Alexandrescu, M.W.Maciejewski, M.Jenny, K.Rathgeb-Szabo, T.Schulthess, R.Landwehr, S.Frank, M.A.Ruegg, R.A.Kammerer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.42
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	101.329, 57.540, 74.621, 90.00, 127.10, 90.00
R / Rfree (%)	22 / 24

The binding sites of Calcium atom in the Modulation of Agrin Function By Alternative Splicing and CA2+ Binding (pdb code 1pz7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Modulation of Agrin Function By Alternative Splicing and CA2+ Binding, PDB code: 1pz7:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Modulation of Agrin Function By Alternative Splicing and CA2+ Binding


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Modulation of Agrin Function By Alternative Splicing and CA2+ Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca701 b:19.3 occ:1.00 O A:LEU93 2.3 8.9 1.0 OD1 A:ASP76 2.3 7.6 1.0 O A:GLN143 2.3 9.3 1.0 O A:HOH809 2.4 15.0 1.0 OD2 A:ASP145 2.5 11.4 1.0 O A:HOH842 2.8 22.6 1.0 CG A:ASP145 3.4 10.4 1.0 CG A:ASP76 3.4 8.5 1.0 C A:LEU93 3.4 8.6 1.0 C A:GLN143 3.5 9.6 1.0 OD2 A:ASP76 3.7 8.7 1.0 N A:ASP145 3.8 9.7 1.0 CA A:LEU93 4.0 8.3 1.0 OD1 A:ASP145 4.1 11.6 1.0 CB A:ASP145 4.1 9.8 1.0 CB A:LEU93 4.2 8.5 1.0 O A:HOH991 4.2 26.5 1.0 CA A:LEU144 4.3 10.0 1.0 O A:HOH808 4.3 19.4 1.0 N A:LEU144 4.3 9.8 1.0 CB A:ALA141 4.4 10.1 1.0 N A:GLY94 4.4 8.9 1.0 CA A:GLN143 4.5 9.5 1.0 C A:LEU144 4.5 9.7 1.0 N A:GLN143 4.6 9.4 1.0 O A:HOH977 4.6 29.9 1.0 CA A:ASP145 4.6 9.7 1.0 O A:HOH1007 4.6 31.6 1.0 CB A:ASP76 4.6 7.7 1.0 CB A:GLN143 4.7 9.7 1.0 CA A:GLY94 4.8 9.0 1.0 O A:HOH1049 4.9 27.9 1.0

Calcium binding site 2 out of 2 in the Modulation of Agrin Function By Alternative Splicing and CA2+ Binding


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Modulation of Agrin Function By Alternative Splicing and CA2+ Binding within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca702 b:21.2 occ:1.00 O B:LEU93 2.3 7.7 1.0 OD2 B:ASP76 2.4 8.8 1.0 O B:GLN143 2.4 10.4 1.0 O B:HOH904 2.4 22.2 1.0 OD1 B:ASP145 2.6 14.2 1.0 O B:HOH731 2.9 20.2 1.0 C B:LEU93 3.4 7.4 1.0 CG B:ASP145 3.4 11.3 1.0 CG B:ASP76 3.4 8.6 1.0 C B:GLN143 3.5 10.7 1.0 OD1 B:ASP76 3.7 8.7 1.0 N B:ASP145 3.8 10.3 1.0 OD2 B:ASP145 4.0 14.2 1.0 CA B:LEU93 4.0 7.7 1.0 CB B:ASP145 4.2 10.8 1.0 CB B:LEU93 4.2 7.5 1.0 CB B:ALA141 4.2 10.8 1.0 CA B:LEU144 4.3 10.7 1.0 N B:LEU144 4.3 10.5 1.0 O B:HOH802 4.4 31.8 1.0 O B:HOH741 4.4 23.2 1.0 N B:GLY94 4.5 7.3 1.0 CA B:GLN143 4.5 11.0 1.0 C B:LEU144 4.5 10.5 1.0 O B:HOH797 4.5 28.8 1.0 N B:GLN143 4.6 10.7 1.0 CA B:ASP145 4.7 10.5 1.0 CB B:ASP76 4.7 7.6 1.0 O B:HOH899 4.8 30.3 1.0 CB B:GLN143 4.8 11.3 1.0 CA B:GLY94 4.8 7.6 1.0 O B:HOH905 4.9 33.5 1.0

J.Stetefeld, A.T.Alexandrescu, M.W.Maciejewski, M.Jenny, K.Rathgeb-Szabo, T.Schulthess, R.Landwehr, S.Frank, M.A.Ruegg, R.A.Kammerer. Modulation of Agrin Function By Alternative Splicing and CA2+ Binding. Structure V. 12 503 2004.
ISSN: ISSN 0969-2126
PubMed: 15016366
DOI: 10.1016/J.STR.2004.02.001