Calcium in PDB 1q3a: Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Enzymatic activity of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10:
3.4.24.22;
Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10, PDB code: 1q3a
was solved by
V.Calderone,
I.Bertini,
M.Fragai,
C.Luchinat,
S.Mangani,
B.Terni,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
51.30 /
2.10
|
Space group
|
C 1 2 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
117.152,
61.141,
68.588,
90.00,
108.68,
90.00
|
R / Rfree (%)
|
27.6 /
29.8
|
Other elements in 1q3a:
The structure of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
(pdb code 1q3a). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 9 binding sites of Calcium where determined in the
Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10, PDB code: 1q3a:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
Calcium binding site 1 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 1 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca466
b:31.9
occ:1.00
|
O
|
A:GLY175
|
2.1
|
31.1
|
1.0
|
OE2
|
A:GLU200
|
2.2
|
22.4
|
1.0
|
OD2
|
A:ASP197
|
2.2
|
19.7
|
1.0
|
O
|
A:SER179
|
2.3
|
30.7
|
1.0
|
O
|
A:GLY177
|
2.4
|
34.9
|
1.0
|
OD2
|
A:ASP174
|
2.5
|
28.9
|
1.0
|
C
|
A:GLY175
|
3.2
|
31.9
|
1.0
|
CG
|
A:ASP197
|
3.4
|
21.2
|
1.0
|
C
|
A:SER179
|
3.4
|
30.6
|
1.0
|
CD
|
A:GLU200
|
3.4
|
24.4
|
1.0
|
CG
|
A:ASP174
|
3.6
|
30.7
|
1.0
|
C
|
A:GLY177
|
3.6
|
34.7
|
1.0
|
N
|
A:SER179
|
3.7
|
33.2
|
1.0
|
CA
|
A:SER179
|
4.0
|
31.8
|
1.0
|
N
|
A:GLY177
|
4.0
|
33.8
|
1.0
|
N
|
A:GLY175
|
4.1
|
31.6
|
1.0
|
OD1
|
A:ASP174
|
4.1
|
30.6
|
1.0
|
OE1
|
A:GLU200
|
4.1
|
23.5
|
1.0
|
CA
|
A:GLY175
|
4.1
|
31.8
|
1.0
|
CB
|
A:ASP197
|
4.1
|
21.3
|
1.0
|
N
|
A:PRO176
|
4.2
|
32.7
|
1.0
|
C
|
A:PRO176
|
4.3
|
33.6
|
1.0
|
OD1
|
A:ASP197
|
4.3
|
21.6
|
1.0
|
C
|
A:ASP174
|
4.4
|
31.7
|
1.0
|
C
|
A:HIS178
|
4.4
|
34.0
|
1.0
|
CA
|
A:GLY177
|
4.4
|
34.2
|
1.0
|
CA
|
A:PRO176
|
4.5
|
33.2
|
1.0
|
N
|
A:LEU180
|
4.5
|
28.8
|
1.0
|
N
|
A:ASP174
|
4.5
|
32.0
|
1.0
|
CG
|
A:GLU200
|
4.5
|
25.4
|
1.0
|
CB
|
A:SER179
|
4.7
|
31.8
|
1.0
|
N
|
A:HIS178
|
4.7
|
34.9
|
1.0
|
CA
|
A:LEU180
|
4.8
|
27.1
|
1.0
|
O
|
A:ASP174
|
4.8
|
32.3
|
1.0
|
CB
|
A:ASP174
|
4.8
|
31.2
|
1.0
|
O
|
A:PRO176
|
4.9
|
33.6
|
1.0
|
CA
|
A:ASP174
|
4.9
|
31.7
|
1.0
|
CA
|
A:HIS178
|
5.0
|
34.4
|
1.0
|
|
Calcium binding site 2 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 2 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca467
b:31.2
occ:1.00
|
O
|
A:TYR191
|
2.2
|
30.1
|
1.0
|
OD1
|
A:ASP193
|
2.3
|
22.2
|
1.0
|
O
|
A:GLY189
|
2.4
|
33.7
|
1.0
|
O
|
A:ASP157
|
2.6
|
33.5
|
1.0
|
CG
|
A:ASP193
|
3.3
|
26.1
|
1.0
|
C
|
A:TYR191
|
3.4
|
30.1
|
1.0
|
OD2
|
A:ASP193
|
3.6
|
26.2
|
1.0
|
C
|
A:GLY189
|
3.6
|
33.6
|
1.0
|
C
|
A:ASP157
|
3.7
|
33.4
|
1.0
|
C
|
A:LEU190
|
4.1
|
32.3
|
1.0
|
N
|
A:ASP193
|
4.1
|
26.8
|
1.0
|
O
|
A:ALA156
|
4.1
|
35.6
|
1.0
|
O
|
A:LEU190
|
4.1
|
32.5
|
1.0
|
N
|
A:TYR191
|
4.2
|
31.5
|
1.0
|
O
|
A:GLY187
|
4.2
|
32.4
|
1.0
|
N
|
A:GLY189
|
4.4
|
33.1
|
1.0
|
N
|
A:GLY192
|
4.4
|
29.0
|
1.0
|
CA
|
A:TYR191
|
4.4
|
31.0
|
1.0
|
CA
|
A:ASP157
|
4.4
|
34.2
|
1.0
|
CA
|
A:GLY192
|
4.5
|
27.9
|
1.0
|
O
|
A:HOH585
|
4.5
|
64.9
|
1.0
|
C
|
A:GLY192
|
4.5
|
27.1
|
1.0
|
CB
|
A:ASP193
|
4.5
|
25.6
|
1.0
|
CA
|
A:GLY189
|
4.5
|
33.2
|
1.0
|
N
|
A:LEU190
|
4.6
|
33.2
|
1.0
|
N
|
A:ILE158
|
4.7
|
32.3
|
1.0
|
CA
|
A:LEU190
|
4.7
|
33.2
|
1.0
|
CH2
|
A:TRP108
|
4.7
|
35.7
|
1.0
|
CG
|
A:MET159
|
4.7
|
28.3
|
1.0
|
CA
|
A:ASP193
|
4.7
|
25.8
|
1.0
|
C
|
A:PRO188
|
4.8
|
32.8
|
1.0
|
CA
|
A:ILE158
|
4.9
|
31.2
|
1.0
|
N
|
A:MET159
|
4.9
|
28.6
|
1.0
|
|
Calcium binding site 3 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 3 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca468
b:25.3
occ:1.00
|
O
|
A:HOH564
|
2.3
|
74.5
|
1.0
|
OD1
|
A:ASP198
|
2.3
|
32.4
|
1.0
|
O
|
A:GLU200
|
2.4
|
26.5
|
1.0
|
O
|
A:ASP198
|
2.5
|
28.3
|
1.0
|
OD2
|
A:ASP123
|
2.6
|
32.4
|
1.0
|
OD1
|
A:ASP123
|
2.8
|
30.2
|
1.0
|
O
|
A:HOH597
|
2.9
|
62.9
|
1.0
|
CG
|
A:ASP123
|
3.1
|
31.5
|
1.0
|
CG
|
A:ASP198
|
3.3
|
29.5
|
1.0
|
C
|
A:ASP198
|
3.3
|
28.0
|
1.0
|
C
|
A:GLU200
|
3.6
|
27.2
|
1.0
|
CA
|
A:ASP198
|
3.8
|
27.3
|
1.0
|
OD2
|
A:ASP198
|
4.1
|
30.3
|
1.0
|
CD1
|
A:TRP202
|
4.1
|
28.5
|
1.0
|
CB
|
A:ASP198
|
4.1
|
27.6
|
1.0
|
N
|
A:GLU200
|
4.1
|
27.7
|
1.0
|
CA
|
A:LYS201
|
4.3
|
28.6
|
1.0
|
N
|
A:ASP199
|
4.3
|
28.1
|
1.0
|
N
|
A:LYS201
|
4.3
|
27.6
|
1.0
|
OG1
|
A:THR121
|
4.4
|
26.9
|
1.0
|
C
|
A:ASP199
|
4.5
|
28.2
|
1.0
|
CA
|
A:GLU200
|
4.6
|
26.9
|
1.0
|
NE1
|
A:TRP202
|
4.6
|
28.5
|
1.0
|
CB
|
A:ASP123
|
4.6
|
30.4
|
1.0
|
CA
|
A:ASP199
|
4.6
|
28.5
|
1.0
|
N
|
A:TRP202
|
4.7
|
28.9
|
1.0
|
O
|
A:HOH506
|
4.7
|
36.9
|
1.0
|
O
|
A:HOH589
|
4.8
|
57.4
|
1.0
|
|
Calcium binding site 4 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 4 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca471
b:26.0
occ:1.00
|
O
|
B:GLY177
|
2.1
|
29.0
|
1.0
|
OD2
|
B:ASP197
|
2.2
|
25.1
|
1.0
|
OE2
|
B:GLU200
|
2.3
|
22.8
|
1.0
|
O
|
B:GLY175
|
2.4
|
33.0
|
1.0
|
O
|
B:SER179
|
2.5
|
28.2
|
1.0
|
OD1
|
B:ASP174
|
2.6
|
30.1
|
1.0
|
CG
|
B:ASP197
|
3.3
|
26.4
|
1.0
|
C
|
B:GLY177
|
3.4
|
30.0
|
1.0
|
CD
|
B:GLU200
|
3.6
|
24.2
|
1.0
|
C
|
B:SER179
|
3.6
|
28.4
|
1.0
|
C
|
B:GLY175
|
3.6
|
32.9
|
1.0
|
CG
|
B:ASP174
|
3.9
|
32.9
|
1.0
|
N
|
B:SER179
|
4.0
|
29.3
|
1.0
|
C
|
B:HIS178
|
4.0
|
29.9
|
1.0
|
N
|
B:GLY177
|
4.1
|
31.6
|
1.0
|
N
|
B:GLY175
|
4.1
|
33.5
|
1.0
|
CB
|
B:ASP197
|
4.1
|
26.1
|
1.0
|
OD1
|
B:ASP197
|
4.1
|
28.3
|
1.0
|
C
|
B:ASP174
|
4.1
|
33.0
|
1.0
|
N
|
B:ASP174
|
4.1
|
32.5
|
1.0
|
CA
|
B:GLY177
|
4.3
|
30.8
|
1.0
|
O
|
B:HIS178
|
4.3
|
30.4
|
1.0
|
C
|
B:PRO176
|
4.3
|
31.7
|
1.0
|
OE1
|
B:GLU200
|
4.3
|
23.9
|
1.0
|
CB
|
B:HIS178
|
4.3
|
30.1
|
1.0
|
CA
|
B:SER179
|
4.3
|
28.9
|
1.0
|
N
|
B:HIS178
|
4.4
|
29.9
|
1.0
|
O
|
B:ASP174
|
4.4
|
33.6
|
1.0
|
CA
|
B:GLY175
|
4.4
|
33.0
|
1.0
|
CA
|
B:HIS178
|
4.5
|
30.1
|
1.0
|
CA
|
B:ASP174
|
4.5
|
32.7
|
1.0
|
OD2
|
B:ASP174
|
4.6
|
34.5
|
1.0
|
N
|
B:PRO176
|
4.6
|
32.4
|
1.0
|
N
|
B:LEU180
|
4.6
|
27.1
|
1.0
|
O
|
B:PRO176
|
4.7
|
31.1
|
1.0
|
CA
|
B:PRO176
|
4.7
|
32.1
|
1.0
|
CG
|
B:GLU200
|
4.7
|
26.4
|
1.0
|
O
|
B:HOH496
|
4.7
|
31.1
|
1.0
|
CB
|
B:ASP174
|
4.8
|
32.2
|
1.0
|
CA
|
B:LEU180
|
4.8
|
26.3
|
1.0
|
CB
|
B:SER179
|
4.9
|
28.9
|
1.0
|
|
Calcium binding site 5 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 5 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca472
b:30.8
occ:1.00
|
O
|
B:ASP157
|
2.3
|
27.9
|
1.0
|
O
|
B:GLY189
|
2.4
|
32.9
|
1.0
|
OD1
|
B:ASP193
|
2.4
|
26.6
|
1.0
|
O
|
B:TYR191
|
2.6
|
29.5
|
1.0
|
O
|
B:HOH513
|
2.9
|
36.8
|
1.0
|
CG
|
B:ASP193
|
3.4
|
26.5
|
1.0
|
C
|
B:ASP157
|
3.5
|
28.8
|
1.0
|
C
|
B:GLY189
|
3.6
|
32.5
|
1.0
|
C
|
B:TYR191
|
3.7
|
29.3
|
1.0
|
OD2
|
B:ASP193
|
3.8
|
26.9
|
1.0
|
O
|
B:ALA156
|
3.8
|
30.6
|
1.0
|
O
|
B:LEU190
|
4.0
|
29.8
|
1.0
|
C
|
B:LEU190
|
4.1
|
30.3
|
1.0
|
N
|
B:ASP193
|
4.1
|
26.4
|
1.0
|
O
|
B:HOH568
|
4.3
|
69.7
|
1.0
|
CA
|
B:ASP157
|
4.3
|
29.6
|
1.0
|
C
|
B:GLY192
|
4.3
|
27.1
|
1.0
|
N
|
B:MET159
|
4.3
|
27.6
|
1.0
|
N
|
B:GLY189
|
4.4
|
33.3
|
1.0
|
N
|
B:ILE158
|
4.4
|
27.9
|
1.0
|
CG
|
B:MET159
|
4.4
|
30.9
|
1.0
|
N
|
B:TYR191
|
4.4
|
29.9
|
1.0
|
CA
|
B:GLY192
|
4.4
|
27.9
|
1.0
|
CA
|
B:GLY189
|
4.5
|
33.0
|
1.0
|
O
|
B:GLY187
|
4.5
|
33.6
|
1.0
|
N
|
B:LEU190
|
4.5
|
31.8
|
1.0
|
N
|
B:GLY192
|
4.5
|
28.8
|
1.0
|
CA
|
B:LEU190
|
4.6
|
31.0
|
1.0
|
CB
|
B:ASP193
|
4.6
|
25.7
|
1.0
|
CA
|
B:ILE158
|
4.6
|
27.7
|
1.0
|
CA
|
B:ASP193
|
4.7
|
25.9
|
1.0
|
CA
|
B:TYR191
|
4.7
|
30.3
|
1.0
|
O
|
B:GLY192
|
4.9
|
26.9
|
1.0
|
C
|
B:ALA156
|
4.9
|
30.5
|
1.0
|
CB
|
B:MET159
|
4.9
|
28.5
|
1.0
|
CH2
|
B:TRP108
|
5.0
|
29.3
|
1.0
|
C
|
B:ILE158
|
5.0
|
27.4
|
1.0
|
OE1
|
B:GLU155
|
5.0
|
31.5
|
1.0
|
|
Calcium binding site 6 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 6 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca473
b:34.1
occ:1.00
|
O
|
B:ASP198
|
2.1
|
29.6
|
1.0
|
OD1
|
B:ASP198
|
2.2
|
29.7
|
1.0
|
O
|
B:GLU200
|
2.3
|
29.2
|
1.0
|
OD2
|
B:ASP123
|
2.5
|
28.4
|
1.0
|
O
|
B:HOH482
|
2.6
|
18.4
|
1.0
|
O
|
B:HOH500
|
2.8
|
28.0
|
1.0
|
OD1
|
B:ASP123
|
2.8
|
29.1
|
1.0
|
CG
|
B:ASP123
|
3.0
|
30.1
|
1.0
|
C
|
B:ASP198
|
3.1
|
29.5
|
1.0
|
CG
|
B:ASP198
|
3.3
|
29.6
|
1.0
|
C
|
B:GLU200
|
3.4
|
29.4
|
1.0
|
CA
|
B:ASP198
|
3.7
|
28.8
|
1.0
|
CB
|
B:ASP198
|
3.9
|
29.1
|
1.0
|
OD2
|
B:ASP198
|
4.2
|
32.3
|
1.0
|
N
|
B:GLU200
|
4.2
|
29.5
|
1.0
|
N
|
B:ASP199
|
4.2
|
30.4
|
1.0
|
CD1
|
B:TRP202
|
4.3
|
26.4
|
1.0
|
N
|
B:LYS201
|
4.3
|
29.9
|
1.0
|
OG1
|
B:THR121
|
4.3
|
24.9
|
1.0
|
CA
|
B:LYS201
|
4.3
|
30.4
|
1.0
|
C
|
B:ASP199
|
4.4
|
30.4
|
1.0
|
CA
|
B:GLU200
|
4.4
|
28.8
|
1.0
|
CA
|
B:ASP199
|
4.5
|
30.6
|
1.0
|
CB
|
B:ASP123
|
4.5
|
29.5
|
1.0
|
N
|
B:TRP202
|
4.7
|
29.8
|
1.0
|
NE1
|
B:TRP202
|
4.8
|
27.0
|
1.0
|
O
|
B:ASP199
|
5.0
|
30.1
|
1.0
|
|
Calcium binding site 7 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 7 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca476
b:36.4
occ:1.00
|
OE1
|
C:GLU200
|
2.3
|
36.3
|
1.0
|
OD1
|
C:ASP174
|
2.4
|
24.5
|
1.0
|
O
|
C:SER179
|
2.4
|
28.0
|
1.0
|
O
|
C:GLY175
|
2.4
|
30.2
|
1.0
|
O
|
C:GLY177
|
2.4
|
30.9
|
1.0
|
OD2
|
C:ASP197
|
2.6
|
29.2
|
1.0
|
CD
|
C:GLU200
|
3.4
|
35.8
|
1.0
|
C
|
C:SER179
|
3.5
|
28.5
|
1.0
|
C
|
C:GLY177
|
3.5
|
30.8
|
1.0
|
C
|
C:GLY175
|
3.6
|
30.4
|
1.0
|
CG
|
C:ASP174
|
3.6
|
26.2
|
1.0
|
CG
|
C:ASP197
|
3.6
|
28.7
|
1.0
|
N
|
C:SER179
|
3.6
|
29.3
|
1.0
|
N
|
C:GLY175
|
3.9
|
28.1
|
1.0
|
C
|
C:HIS178
|
3.9
|
29.6
|
1.0
|
OE2
|
C:GLU200
|
4.1
|
33.5
|
1.0
|
C
|
C:ASP174
|
4.1
|
27.3
|
1.0
|
CA
|
C:SER179
|
4.1
|
28.7
|
1.0
|
N
|
C:ASP174
|
4.2
|
26.8
|
1.0
|
N
|
C:GLY177
|
4.2
|
31.0
|
1.0
|
CB
|
C:ASP197
|
4.2
|
28.5
|
1.0
|
CB
|
C:HIS178
|
4.2
|
29.9
|
1.0
|
OD2
|
C:ASP174
|
4.3
|
25.1
|
1.0
|
CA
|
C:GLY175
|
4.3
|
29.3
|
1.0
|
N
|
C:HIS178
|
4.4
|
30.6
|
1.0
|
CA
|
C:HIS178
|
4.4
|
30.0
|
1.0
|
O
|
C:HIS178
|
4.4
|
29.6
|
1.0
|
CG
|
C:GLU200
|
4.5
|
35.4
|
1.0
|
C
|
C:PRO176
|
4.5
|
30.9
|
1.0
|
CA
|
C:GLY177
|
4.5
|
31.1
|
1.0
|
N
|
C:LEU180
|
4.5
|
28.6
|
1.0
|
CA
|
C:ASP174
|
4.5
|
26.9
|
1.0
|
O
|
C:ASP174
|
4.6
|
27.2
|
1.0
|
CB
|
C:ASP174
|
4.6
|
26.5
|
1.0
|
OD1
|
C:ASP197
|
4.6
|
30.0
|
1.0
|
N
|
C:PRO176
|
4.6
|
31.0
|
1.0
|
CA
|
C:LEU180
|
4.8
|
28.5
|
1.0
|
CA
|
C:PRO176
|
4.8
|
31.2
|
1.0
|
O
|
C:PRO176
|
4.9
|
31.0
|
1.0
|
CB
|
C:SER179
|
5.0
|
29.1
|
1.0
|
|
Calcium binding site 8 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 8 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca477
b:40.5
occ:1.00
|
O
|
C:ASP157
|
2.0
|
25.9
|
1.0
|
O
|
C:HOH498
|
2.3
|
30.0
|
1.0
|
O
|
C:TYR191
|
2.4
|
29.1
|
1.0
|
OD2
|
C:ASP193
|
2.4
|
24.2
|
1.0
|
O
|
C:GLY189
|
2.8
|
31.8
|
1.0
|
C
|
C:ASP157
|
3.2
|
27.1
|
1.0
|
CG
|
C:ASP193
|
3.4
|
23.3
|
1.0
|
C
|
C:TYR191
|
3.4
|
29.0
|
1.0
|
OD1
|
C:ASP193
|
3.8
|
23.5
|
1.0
|
C
|
C:GLY189
|
3.9
|
31.4
|
1.0
|
N
|
C:ASP193
|
4.0
|
25.0
|
1.0
|
O
|
C:ALA156
|
4.0
|
29.1
|
1.0
|
CA
|
C:GLY192
|
4.1
|
26.5
|
1.0
|
N
|
C:ILE158
|
4.1
|
25.9
|
1.0
|
CA
|
C:ASP157
|
4.2
|
28.2
|
1.0
|
N
|
C:GLY192
|
4.2
|
27.8
|
1.0
|
CA
|
C:ILE158
|
4.2
|
25.3
|
1.0
|
C
|
C:GLY192
|
4.2
|
25.8
|
1.0
|
C
|
C:LEU190
|
4.3
|
30.3
|
1.0
|
O
|
C:LEU190
|
4.3
|
29.6
|
1.0
|
N
|
C:TYR191
|
4.3
|
30.3
|
1.0
|
N
|
C:GLY189
|
4.4
|
31.6
|
1.0
|
CA
|
C:TYR191
|
4.5
|
30.4
|
1.0
|
N
|
C:MET159
|
4.5
|
24.5
|
1.0
|
CB
|
C:ASP193
|
4.5
|
24.8
|
1.0
|
CA
|
C:ASP193
|
4.6
|
25.0
|
1.0
|
CA
|
C:GLY189
|
4.7
|
31.5
|
1.0
|
CH2
|
C:TRP108
|
4.8
|
38.9
|
1.0
|
O
|
C:GLY187
|
4.8
|
31.7
|
1.0
|
N
|
C:LEU190
|
4.8
|
30.8
|
1.0
|
C
|
C:ILE158
|
4.8
|
24.9
|
1.0
|
OE2
|
C:GLU155
|
4.8
|
42.2
|
1.0
|
CA
|
C:LEU190
|
4.8
|
30.6
|
1.0
|
C
|
C:ALA156
|
4.9
|
29.8
|
1.0
|
|
Calcium binding site 9 out
of 9 in 1q3a
Go back to
Calcium Binding Sites List in 1q3a
Calcium binding site 9 out
of 9 in the Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca478
b:44.6
occ:1.00
|
OD1
|
C:ASP123
|
2.0
|
38.4
|
1.0
|
O
|
C:GLU200
|
2.5
|
33.9
|
1.0
|
O
|
C:ASP198
|
2.7
|
36.2
|
1.0
|
CG
|
C:ASP123
|
2.7
|
37.0
|
1.0
|
OD2
|
C:ASP123
|
2.7
|
38.6
|
1.0
|
OD1
|
C:ASP198
|
2.8
|
38.2
|
1.0
|
C
|
C:GLU200
|
3.5
|
34.9
|
1.0
|
C
|
C:ASP198
|
3.6
|
35.2
|
1.0
|
CG
|
C:ASP198
|
3.7
|
36.7
|
1.0
|
CA
|
C:LYS201
|
4.0
|
35.0
|
1.0
|
CD1
|
C:TRP202
|
4.0
|
35.2
|
1.0
|
CA
|
C:ASP198
|
4.1
|
34.5
|
1.0
|
CB
|
C:ASP123
|
4.1
|
35.3
|
1.0
|
N
|
C:LYS201
|
4.1
|
34.6
|
1.0
|
CB
|
C:ASP198
|
4.4
|
35.2
|
1.0
|
OD2
|
C:ASP198
|
4.5
|
36.6
|
1.0
|
N
|
C:GLU200
|
4.6
|
35.9
|
1.0
|
NE1
|
C:TRP202
|
4.6
|
33.9
|
1.0
|
C
|
C:ASP199
|
4.6
|
36.3
|
1.0
|
N
|
C:TRP202
|
4.6
|
35.2
|
1.0
|
N
|
C:ASP199
|
4.6
|
35.9
|
1.0
|
CA
|
C:GLU200
|
4.7
|
35.2
|
1.0
|
OG1
|
C:THR121
|
4.7
|
30.6
|
1.0
|
CB
|
C:LYS201
|
4.8
|
34.4
|
1.0
|
CA
|
C:ASP199
|
4.9
|
36.5
|
1.0
|
C
|
C:LYS201
|
4.9
|
34.9
|
1.0
|
O
|
C:ASP199
|
5.0
|
36.4
|
1.0
|
|
Reference:
I.Bertini,
V.Calderone,
M.Fragai,
C.Luchinat,
S.Mangani,
B.Terni.
Crystal Structure of the Catalytic Domain of Human Matrix Metalloproteinase 10. J.Mol.Biol. V. 336 707 2004.
ISSN: ISSN 0022-2836
PubMed: 15095982
DOI: 10.1016/J.JMB.2003.12.033
Page generated: Thu Jul 11 13:58:30 2024
|