Calcium in PDB 1qic: Crystal Structure of Stromelysin Catalytic Domain
Enzymatic activity of Crystal Structure of Stromelysin Catalytic Domain
All present enzymatic activity of Crystal Structure of Stromelysin Catalytic Domain:
3.4.24.17;
Protein crystallography data
The structure of Crystal Structure of Stromelysin Catalytic Domain, PDB code: 1qic
was solved by
M.G.Williams,
Q.-Z.Ye,
F.Molina,
L.L.Johnson,
D.F.Ortwine,
A.G.Pavlovsky,
J.R.Rubin,
R.W.Skeean,
A.D.White,
T.L.Blundell,
C.Humblet,
D.J.Hupe,
V.Dhanaraj,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
20.00 /
2.00
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
71.250,
59.320,
72.300,
90.00,
101.64,
90.00
|
|
R / Rfree (%)
|
23 /
27
|
Other elements in 1qic:
The structure of Crystal Structure of Stromelysin Catalytic Domain also contains other interesting chemical elements:
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Calcium atom in the Crystal Structure of Stromelysin Catalytic Domain
(pdb code 1qic). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the
Crystal Structure of Stromelysin Catalytic Domain, PDB code: 1qic:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 1 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca503
b:28.4
occ:1.00
|
O
|
A:GLY161
|
2.6
|
15.1
|
1.0
|
|
O
|
A:GLY159
|
2.6
|
4.0
|
1.0
|
|
O
|
A:VAL163
|
2.6
|
19.4
|
1.0
|
|
OD2
|
A:ASP181
|
2.7
|
20.6
|
1.0
|
|
OD1
|
A:ASP158
|
2.8
|
15.3
|
1.0
|
|
OE2
|
A:GLU184
|
2.8
|
8.5
|
1.0
|
|
C
|
A:VAL163
|
3.4
|
17.5
|
1.0
|
|
C
|
A:GLY161
|
3.6
|
15.2
|
1.0
|
|
CG
|
A:ASP181
|
3.7
|
19.4
|
1.0
|
|
C
|
A:GLY159
|
3.8
|
7.8
|
1.0
|
|
N
|
A:VAL163
|
3.9
|
20.0
|
1.0
|
|
CD
|
A:GLU184
|
3.9
|
11.6
|
1.0
|
|
CG
|
A:ASP158
|
4.0
|
14.5
|
1.0
|
|
N
|
A:GLY161
|
4.1
|
14.0
|
1.0
|
|
C
|
A:ASN162
|
4.1
|
18.4
|
1.0
|
|
CB
|
A:ASP181
|
4.1
|
13.2
|
1.0
|
|
CA
|
A:VAL163
|
4.1
|
17.6
|
1.0
|
|
N
|
A:LEU164
|
4.2
|
15.5
|
1.0
|
|
N
|
A:GLY159
|
4.3
|
3.8
|
1.0
|
|
C
|
A:PRO160
|
4.4
|
12.8
|
1.0
|
|
CA
|
A:LEU164
|
4.4
|
15.4
|
1.0
|
|
CG
|
A:GLU184
|
4.4
|
12.1
|
1.0
|
|
CA
|
A:GLY161
|
4.4
|
13.7
|
1.0
|
|
N
|
A:ASN162
|
4.5
|
17.6
|
1.0
|
|
C
|
A:ASP158
|
4.5
|
5.1
|
1.0
|
|
N
|
A:ASP158
|
4.5
|
10.6
|
1.0
|
|
O
|
A:ASN162
|
4.5
|
20.4
|
1.0
|
|
CA
|
A:ASN162
|
4.6
|
18.7
|
1.0
|
|
CA
|
A:GLY159
|
4.6
|
7.5
|
1.0
|
|
CB
|
A:VAL163
|
4.7
|
15.7
|
1.0
|
|
OD2
|
A:ASP158
|
4.7
|
15.9
|
1.0
|
|
N
|
A:PRO160
|
4.7
|
9.2
|
1.0
|
|
CB
|
A:ASN162
|
4.7
|
19.0
|
1.0
|
|
OD1
|
A:ASP181
|
4.7
|
23.6
|
1.0
|
|
CA
|
A:PRO160
|
4.7
|
10.8
|
1.0
|
|
CA
|
A:ASP158
|
4.8
|
6.7
|
1.0
|
|
O
|
A:PRO160
|
4.9
|
15.0
|
1.0
|
|
CB
|
A:ASP158
|
4.9
|
11.5
|
1.0
|
|
OE1
|
A:GLU184
|
4.9
|
13.8
|
1.0
|
|
O
|
A:ASP158
|
5.0
|
5.3
|
1.0
|
|
Calcium binding site 2 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 2 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca504
b:11.3
occ:1.00
|
O
|
A:GLY173
|
2.5
|
10.9
|
1.0
|
|
O
|
A:HOH301
|
2.6
|
20.0
|
1.0
|
|
O
|
A:ASP141
|
2.6
|
22.2
|
1.0
|
|
O
|
A:ASN175
|
2.6
|
15.6
|
1.0
|
|
OD1
|
A:ASP177
|
2.7
|
18.9
|
1.0
|
|
C
|
A:ASP141
|
3.5
|
19.0
|
1.0
|
|
O
|
A:ALA140
|
3.7
|
19.8
|
1.0
|
|
C
|
A:GLY173
|
3.7
|
9.6
|
1.0
|
|
OE2
|
A:GLU139
|
3.8
|
52.2
|
1.0
|
|
C
|
A:ASN175
|
3.8
|
16.2
|
1.0
|
|
CG
|
A:ASP177
|
3.9
|
18.2
|
1.0
|
|
CA
|
A:ASP141
|
4.1
|
18.6
|
1.0
|
|
N
|
A:ASP177
|
4.3
|
17.4
|
1.0
|
|
N
|
A:ILE142
|
4.4
|
16.8
|
1.0
|
|
C
|
A:ILE174
|
4.4
|
14.8
|
1.0
|
|
OD2
|
A:ASP177
|
4.5
|
18.3
|
1.0
|
|
CA
|
A:GLY173
|
4.5
|
10.0
|
1.0
|
|
N
|
A:ASN175
|
4.5
|
14.0
|
1.0
|
|
N
|
A:GLY173
|
4.5
|
11.2
|
1.0
|
|
C
|
A:GLY176
|
4.5
|
18.2
|
1.0
|
|
O
|
A:ILE174
|
4.6
|
14.1
|
1.0
|
|
CA
|
A:GLY176
|
4.6
|
18.7
|
1.0
|
|
N
|
A:GLY176
|
4.6
|
17.2
|
1.0
|
|
O
|
A:GLY171
|
4.7
|
11.5
|
1.0
|
|
C
|
A:PRO172
|
4.7
|
14.2
|
1.0
|
|
C
|
A:ALA140
|
4.7
|
20.8
|
1.0
|
|
N
|
A:ILE174
|
4.7
|
11.8
|
1.0
|
|
N
|
A:MET143
|
4.7
|
11.7
|
1.0
|
|
O
|
A:PRO172
|
4.7
|
16.7
|
1.0
|
|
CG
|
A:MET143
|
4.7
|
4.2
|
1.0
|
|
CA
|
A:ILE142
|
4.7
|
12.8
|
1.0
|
|
CA
|
A:ASN175
|
4.8
|
15.7
|
1.0
|
|
CA
|
A:ILE174
|
4.9
|
14.2
|
1.0
|
|
N
|
A:ASP141
|
4.9
|
18.8
|
1.0
|
|
CA
|
A:ASP177
|
4.9
|
15.3
|
1.0
|
|
CB
|
A:ASP177
|
5.0
|
15.8
|
1.0
|
|
Calcium binding site 3 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 3 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca505
b:13.8
occ:1.00
|
O
|
A:GLU184
|
2.7
|
11.9
|
1.0
|
|
OD2
|
A:ASP107
|
2.7
|
9.9
|
1.0
|
|
O
|
A:HOH302
|
2.9
|
20.0
|
1.0
|
|
O
|
A:ASP182
|
2.9
|
17.6
|
1.0
|
|
OD1
|
A:ASP182
|
3.0
|
13.6
|
1.0
|
|
OD1
|
A:ASP107
|
3.1
|
12.3
|
1.0
|
|
CG
|
A:ASP107
|
3.2
|
8.7
|
1.0
|
|
C
|
A:ASP182
|
3.6
|
15.5
|
1.0
|
|
C
|
A:GLU184
|
3.9
|
13.0
|
1.0
|
|
CG
|
A:ASP182
|
4.1
|
16.6
|
1.0
|
|
CA
|
A:ASP182
|
4.3
|
14.7
|
1.0
|
|
N
|
A:GLU184
|
4.3
|
13.5
|
1.0
|
|
C
|
A:ASP183
|
4.4
|
13.4
|
1.0
|
|
N
|
A:ASP183
|
4.4
|
14.2
|
1.0
|
|
OG1
|
A:THR105
|
4.4
|
10.5
|
1.0
|
|
CA
|
A:ASP183
|
4.5
|
14.6
|
1.0
|
|
CA
|
A:GLN185
|
4.6
|
16.4
|
1.0
|
|
CB
|
A:ASP182
|
4.6
|
15.9
|
1.0
|
|
N
|
A:GLN185
|
4.7
|
14.6
|
1.0
|
|
CB
|
A:ASP107
|
4.7
|
8.1
|
1.0
|
|
O
|
A:ASP183
|
4.8
|
14.4
|
1.0
|
|
CA
|
A:GLU184
|
4.8
|
12.6
|
1.0
|
|
CG
|
A:GLN185
|
5.0
|
26.4
|
1.0
|
|
Calcium binding site 4 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 4 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca503
b:18.4
occ:1.00
|
O
|
B:GLY161
|
2.6
|
18.5
|
1.0
|
|
O
|
B:GLY159
|
2.6
|
11.7
|
1.0
|
|
O
|
B:VAL163
|
2.6
|
18.1
|
1.0
|
|
OD2
|
B:ASP181
|
2.7
|
16.0
|
1.0
|
|
OD1
|
B:ASP158
|
2.8
|
15.3
|
1.0
|
|
OE2
|
B:GLU184
|
3.0
|
21.2
|
1.0
|
|
CD
|
B:GLU184
|
3.4
|
19.3
|
1.0
|
|
OE1
|
B:GLU184
|
3.4
|
23.8
|
1.0
|
|
C
|
B:VAL163
|
3.4
|
17.5
|
1.0
|
|
C
|
B:GLY161
|
3.6
|
16.5
|
1.0
|
|
CG
|
B:ASP181
|
3.7
|
17.2
|
1.0
|
|
C
|
B:GLY159
|
3.8
|
13.8
|
1.0
|
|
N
|
B:VAL163
|
3.9
|
16.6
|
1.0
|
|
CG
|
B:ASP158
|
4.0
|
15.7
|
1.0
|
|
N
|
B:GLY161
|
4.0
|
11.7
|
1.0
|
|
CB
|
B:ASP181
|
4.1
|
15.4
|
1.0
|
|
N
|
B:LEU164
|
4.2
|
17.4
|
1.0
|
|
C
|
B:ASN162
|
4.2
|
16.6
|
1.0
|
|
CA
|
B:VAL163
|
4.2
|
16.4
|
1.0
|
|
CA
|
B:LEU164
|
4.3
|
18.3
|
1.0
|
|
C
|
B:PRO160
|
4.3
|
11.8
|
1.0
|
|
CA
|
B:GLY161
|
4.4
|
14.4
|
1.0
|
|
N
|
B:GLY159
|
4.4
|
12.2
|
1.0
|
|
N
|
B:ASN162
|
4.5
|
17.6
|
1.0
|
|
C
|
B:ASP158
|
4.6
|
13.8
|
1.0
|
|
CG
|
B:GLU184
|
4.6
|
17.8
|
1.0
|
|
N
|
B:ASP158
|
4.6
|
11.7
|
1.0
|
|
O
|
B:ASN162
|
4.6
|
17.8
|
1.0
|
|
CA
|
B:ASN162
|
4.7
|
17.6
|
1.0
|
|
CA
|
B:GLY159
|
4.7
|
12.5
|
1.0
|
|
N
|
B:PRO160
|
4.7
|
13.9
|
1.0
|
|
CB
|
B:VAL163
|
4.7
|
16.5
|
1.0
|
|
CA
|
B:PRO160
|
4.7
|
12.2
|
1.0
|
|
OD2
|
B:ASP158
|
4.7
|
20.4
|
1.0
|
|
OD1
|
B:ASP181
|
4.7
|
20.1
|
1.0
|
|
CB
|
B:ASN162
|
4.8
|
20.2
|
1.0
|
|
O
|
B:PRO160
|
4.8
|
11.5
|
1.0
|
|
CA
|
B:ASP158
|
4.9
|
13.5
|
1.0
|
|
C
|
B:LEU164
|
5.0
|
18.3
|
1.0
|
|
Calcium binding site 5 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 5 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca504
b:20.5
occ:1.00
|
O
|
B:GLY173
|
2.5
|
11.0
|
1.0
|
|
O
|
B:ASP141
|
2.6
|
22.7
|
1.0
|
|
O
|
B:ASN175
|
2.7
|
15.5
|
1.0
|
|
OD1
|
B:ASP177
|
2.8
|
17.5
|
1.0
|
|
O
|
B:HOH303
|
2.9
|
20.0
|
1.0
|
|
C
|
B:ASP141
|
3.5
|
19.8
|
1.0
|
|
O
|
B:ALA140
|
3.6
|
22.4
|
1.0
|
|
C
|
B:GLY173
|
3.7
|
11.6
|
1.0
|
|
OE2
|
B:GLU139
|
3.7
|
54.4
|
1.0
|
|
C
|
B:ASN175
|
3.9
|
17.3
|
1.0
|
|
CG
|
B:ASP177
|
3.9
|
15.5
|
1.0
|
|
CA
|
B:ASP141
|
4.0
|
19.4
|
1.0
|
|
N
|
B:ASP177
|
4.4
|
15.0
|
1.0
|
|
CA
|
B:GLY173
|
4.4
|
10.6
|
1.0
|
|
N
|
B:ILE142
|
4.4
|
19.2
|
1.0
|
|
N
|
B:GLY173
|
4.5
|
14.4
|
1.0
|
|
OD2
|
B:ASP177
|
4.5
|
18.2
|
1.0
|
|
C
|
B:ILE174
|
4.5
|
16.9
|
1.0
|
|
N
|
B:ASN175
|
4.6
|
15.8
|
1.0
|
|
C
|
B:ALA140
|
4.6
|
22.2
|
1.0
|
|
O
|
B:GLY171
|
4.6
|
13.3
|
1.0
|
|
C
|
B:PRO172
|
4.6
|
13.3
|
1.0
|
|
CA
|
B:GLY176
|
4.6
|
17.5
|
1.0
|
|
C
|
B:GLY176
|
4.6
|
17.4
|
1.0
|
|
O
|
B:ILE174
|
4.7
|
17.2
|
1.0
|
|
CG
|
B:MET143
|
4.7
|
17.1
|
1.0
|
|
N
|
B:GLY176
|
4.7
|
19.5
|
1.0
|
|
O
|
B:PRO172
|
4.7
|
11.3
|
1.0
|
|
N
|
B:ILE174
|
4.7
|
14.0
|
1.0
|
|
CA
|
B:ILE142
|
4.8
|
15.9
|
1.0
|
|
N
|
B:MET143
|
4.8
|
17.1
|
1.0
|
|
CA
|
B:ASN175
|
4.8
|
17.2
|
1.0
|
|
N
|
B:ASP141
|
4.8
|
21.5
|
1.0
|
|
CA
|
B:ILE174
|
5.0
|
14.7
|
1.0
|
|
CD
|
B:GLU139
|
5.0
|
52.6
|
1.0
|
|
Calcium binding site 6 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 6 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca505
b:20.5
occ:1.00
|
O
|
B:GLU184
|
2.6
|
14.2
|
1.0
|
|
OD2
|
B:ASP107
|
2.7
|
17.1
|
1.0
|
|
O
|
B:ASP182
|
2.7
|
18.3
|
1.0
|
|
OD1
|
B:ASP182
|
2.8
|
16.8
|
1.0
|
|
OD1
|
B:ASP107
|
2.9
|
14.6
|
1.0
|
|
CG
|
B:ASP107
|
3.2
|
13.8
|
1.0
|
|
O
|
B:HOH304
|
3.3
|
20.0
|
1.0
|
|
C
|
B:ASP182
|
3.5
|
17.3
|
1.0
|
|
C
|
B:GLU184
|
3.8
|
15.3
|
1.0
|
|
CG
|
B:ASP182
|
4.0
|
18.1
|
1.0
|
|
CA
|
B:ASP182
|
4.2
|
16.6
|
1.0
|
|
N
|
B:GLU184
|
4.2
|
12.5
|
1.0
|
|
C
|
B:ASP183
|
4.3
|
15.6
|
1.0
|
|
N
|
B:ASP183
|
4.3
|
14.9
|
1.0
|
|
OG1
|
B:THR105
|
4.4
|
7.3
|
1.0
|
|
CA
|
B:ASP183
|
4.4
|
15.3
|
1.0
|
|
CB
|
B:ASP182
|
4.5
|
17.2
|
1.0
|
|
NE2
|
B:GLN185
|
4.6
|
18.2
|
1.0
|
|
CA
|
B:GLN185
|
4.6
|
12.9
|
1.0
|
|
N
|
B:GLN185
|
4.6
|
14.4
|
1.0
|
|
CB
|
B:ASP107
|
4.7
|
13.6
|
1.0
|
|
CA
|
B:GLU184
|
4.7
|
14.7
|
1.0
|
|
O
|
B:ASP183
|
4.7
|
19.4
|
1.0
|
|
CD
|
B:GLN185
|
4.8
|
18.9
|
1.0
|
|
OD2
|
B:ASP182
|
5.0
|
19.3
|
1.0
|
|
Calcium binding site 7 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 7 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca503
b:13.4
occ:1.00
|
O
|
C:VAL163
|
2.4
|
19.8
|
1.0
|
|
O
|
C:GLY159
|
2.5
|
11.4
|
1.0
|
|
OE2
|
C:GLU184
|
2.6
|
18.6
|
1.0
|
|
OD2
|
C:ASP181
|
2.7
|
21.9
|
1.0
|
|
OD1
|
C:ASP158
|
2.7
|
10.6
|
1.0
|
|
O
|
C:GLY161
|
2.8
|
17.0
|
1.0
|
|
C
|
C:VAL163
|
3.3
|
19.0
|
1.0
|
|
CD
|
C:GLU184
|
3.6
|
17.6
|
1.0
|
|
C
|
C:GLY159
|
3.7
|
12.3
|
1.0
|
|
C
|
C:GLY161
|
3.7
|
17.4
|
1.0
|
|
CG
|
C:ASP181
|
3.7
|
19.1
|
1.0
|
|
CG
|
C:ASP158
|
3.9
|
10.7
|
1.0
|
|
N
|
C:VAL163
|
3.9
|
19.3
|
1.0
|
|
CA
|
C:VAL163
|
4.1
|
18.8
|
1.0
|
|
N
|
C:GLY161
|
4.1
|
13.6
|
1.0
|
|
CB
|
C:ASP181
|
4.2
|
15.3
|
1.0
|
|
OE1
|
C:GLU184
|
4.2
|
15.1
|
1.0
|
|
C
|
C:ASN162
|
4.2
|
19.6
|
1.0
|
|
N
|
C:GLY159
|
4.2
|
12.0
|
1.0
|
|
N
|
C:LEU164
|
4.3
|
17.7
|
1.0
|
|
C
|
C:PRO160
|
4.4
|
13.9
|
1.0
|
|
C
|
C:ASP158
|
4.4
|
9.9
|
1.0
|
|
N
|
C:ASP158
|
4.4
|
13.2
|
1.0
|
|
CA
|
C:LEU164
|
4.5
|
17.4
|
1.0
|
|
CA
|
C:GLY161
|
4.5
|
14.8
|
1.0
|
|
CG
|
C:GLU184
|
4.5
|
17.6
|
1.0
|
|
CB
|
C:VAL163
|
4.6
|
19.3
|
1.0
|
|
N
|
C:ASN162
|
4.6
|
18.5
|
1.0
|
|
CA
|
C:GLY159
|
4.6
|
11.7
|
1.0
|
|
O
|
C:ASN162
|
4.6
|
20.7
|
1.0
|
|
OD2
|
C:ASP158
|
4.6
|
9.6
|
1.0
|
|
N
|
C:PRO160
|
4.6
|
13.3
|
1.0
|
|
CA
|
C:PRO160
|
4.7
|
13.4
|
1.0
|
|
CA
|
C:ASP158
|
4.7
|
10.4
|
1.0
|
|
CA
|
C:ASN162
|
4.8
|
18.9
|
1.0
|
|
CB
|
C:ASN162
|
4.8
|
23.7
|
1.0
|
|
OD1
|
C:ASP181
|
4.8
|
18.2
|
1.0
|
|
O
|
C:PRO160
|
4.8
|
14.1
|
1.0
|
|
CB
|
C:ASP158
|
4.9
|
10.1
|
1.0
|
|
O
|
C:ASP158
|
4.9
|
8.7
|
1.0
|
|
Calcium binding site 8 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 8 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca504
b:17.9
occ:1.00
|
O
|
C:GLY173
|
2.5
|
10.0
|
1.0
|
|
O
|
C:HOH305
|
2.5
|
20.0
|
1.0
|
|
O
|
C:ASP141
|
2.6
|
19.4
|
1.0
|
|
O
|
C:ASN175
|
2.7
|
17.0
|
1.0
|
|
OD1
|
C:ASP177
|
2.8
|
19.4
|
1.0
|
|
C
|
C:ASP141
|
3.5
|
16.4
|
1.0
|
|
O
|
C:ALA140
|
3.7
|
17.6
|
1.0
|
|
C
|
C:GLY173
|
3.7
|
10.8
|
1.0
|
|
OE2
|
C:GLU139
|
3.7
|
43.2
|
1.0
|
|
C
|
C:ASN175
|
3.8
|
14.3
|
1.0
|
|
CG
|
C:ASP177
|
3.9
|
24.1
|
1.0
|
|
CA
|
C:ASP141
|
4.1
|
17.9
|
1.0
|
|
N
|
C:ASP177
|
4.4
|
17.5
|
1.0
|
|
CA
|
C:GLY173
|
4.4
|
11.8
|
1.0
|
|
N
|
C:ILE142
|
4.4
|
14.3
|
1.0
|
|
OD2
|
C:ASP177
|
4.4
|
26.0
|
1.0
|
|
C
|
C:ILE174
|
4.5
|
12.8
|
1.0
|
|
N
|
C:GLY173
|
4.5
|
12.7
|
1.0
|
|
N
|
C:ASN175
|
4.5
|
13.5
|
1.0
|
|
O
|
C:ILE174
|
4.6
|
14.5
|
1.0
|
|
C
|
C:GLY176
|
4.6
|
18.0
|
1.0
|
|
CA
|
C:GLY176
|
4.6
|
16.1
|
1.0
|
|
O
|
C:GLY171
|
4.6
|
12.0
|
1.0
|
|
C
|
C:PRO172
|
4.6
|
10.9
|
1.0
|
|
N
|
C:GLY176
|
4.7
|
13.8
|
1.0
|
|
C
|
C:ALA140
|
4.7
|
19.0
|
1.0
|
|
O
|
C:PRO172
|
4.7
|
9.0
|
1.0
|
|
N
|
C:ILE174
|
4.7
|
12.7
|
1.0
|
|
CG
|
C:MET143
|
4.7
|
18.3
|
1.0
|
|
CA
|
C:ILE142
|
4.7
|
11.4
|
1.0
|
|
N
|
C:MET143
|
4.7
|
12.3
|
1.0
|
|
CA
|
C:ASN175
|
4.8
|
13.9
|
1.0
|
|
CA
|
C:ILE174
|
4.9
|
12.6
|
1.0
|
|
N
|
C:ASP141
|
4.9
|
18.2
|
1.0
|
|
CB
|
C:ASP177
|
5.0
|
20.8
|
1.0
|
|
CA
|
C:ASP177
|
5.0
|
17.1
|
1.0
|
|
CD
|
C:GLU139
|
5.0
|
43.5
|
1.0
|
|
Calcium binding site 9 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 9 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca505
b:12.6
occ:1.00
|
O
|
C:GLU184
|
2.6
|
16.1
|
1.0
|
|
O
|
C:ASP182
|
2.8
|
14.9
|
1.0
|
|
OD2
|
C:ASP107
|
2.8
|
6.5
|
1.0
|
|
O
|
C:HOH306
|
2.9
|
20.0
|
1.0
|
|
OD1
|
C:ASP107
|
3.0
|
8.0
|
1.0
|
|
OD1
|
C:ASP182
|
3.1
|
13.7
|
1.0
|
|
CG
|
C:ASP107
|
3.3
|
7.6
|
1.0
|
|
C
|
C:ASP182
|
3.5
|
11.9
|
1.0
|
|
C
|
C:GLU184
|
3.8
|
17.3
|
1.0
|
|
CG
|
C:ASP182
|
4.1
|
16.3
|
1.0
|
|
N
|
C:GLU184
|
4.2
|
15.8
|
1.0
|
|
C
|
C:ASP183
|
4.2
|
14.3
|
1.0
|
|
CA
|
C:ASP182
|
4.3
|
10.2
|
1.0
|
|
N
|
C:ASP183
|
4.3
|
12.3
|
1.0
|
|
CA
|
C:ASP183
|
4.4
|
13.6
|
1.0
|
|
CA
|
C:GLN185
|
4.5
|
16.9
|
1.0
|
|
N
|
C:GLN185
|
4.6
|
17.4
|
1.0
|
|
O
|
C:ASP183
|
4.6
|
17.4
|
1.0
|
|
CB
|
C:ASP182
|
4.6
|
12.4
|
1.0
|
|
CA
|
C:GLU184
|
4.7
|
15.3
|
1.0
|
|
OG1
|
C:THR105
|
4.7
|
17.0
|
1.0
|
|
CB
|
C:ASP107
|
4.8
|
12.9
|
1.0
|
|
OD2
|
C:ASP182
|
4.9
|
19.9
|
1.0
|
|
Calcium binding site 10 out
of 12 in 1qic
Go back to
Calcium Binding Sites List in 1qic
Calcium binding site 10 out
of 12 in the Crystal Structure of Stromelysin Catalytic Domain
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Crystal Structure of Stromelysin Catalytic Domain within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca503
b:16.4
occ:1.00
|
O
|
D:GLY161
|
2.5
|
14.1
|
1.0
|
|
O
|
D:GLY159
|
2.5
|
8.8
|
1.0
|
|
O
|
D:VAL163
|
2.7
|
18.3
|
1.0
|
|
OD2
|
D:ASP181
|
2.7
|
9.4
|
1.0
|
|
OD1
|
D:ASP158
|
2.8
|
14.3
|
1.0
|
|
OE1
|
D:GLU184
|
3.0
|
8.6
|
1.0
|
|
CD
|
D:GLU184
|
3.3
|
8.0
|
1.0
|
|
OE2
|
D:GLU184
|
3.3
|
9.8
|
1.0
|
|
C
|
D:VAL163
|
3.4
|
19.1
|
1.0
|
|
C
|
D:GLY161
|
3.5
|
16.4
|
1.0
|
|
C
|
D:GLY159
|
3.7
|
11.7
|
1.0
|
|
CG
|
D:ASP181
|
3.7
|
9.4
|
1.0
|
|
N
|
D:VAL163
|
3.9
|
21.1
|
1.0
|
|
N
|
D:GLY161
|
4.0
|
13.4
|
1.0
|
|
CG
|
D:ASP158
|
4.0
|
13.8
|
1.0
|
|
C
|
D:ASN162
|
4.1
|
22.2
|
1.0
|
|
CA
|
D:VAL163
|
4.2
|
19.9
|
1.0
|
|
CB
|
D:ASP181
|
4.2
|
9.4
|
1.0
|
|
N
|
D:LEU164
|
4.2
|
17.4
|
1.0
|
|
C
|
D:PRO160
|
4.3
|
13.1
|
1.0
|
|
N
|
D:GLY159
|
4.3
|
13.7
|
1.0
|
|
CA
|
D:GLY161
|
4.3
|
13.8
|
1.0
|
|
CG
|
D:GLU184
|
4.4
|
9.4
|
1.0
|
|
N
|
D:ASN162
|
4.4
|
19.7
|
1.0
|
|
CA
|
D:LEU164
|
4.4
|
16.6
|
1.0
|
|
C
|
D:ASP158
|
4.5
|
13.2
|
1.0
|
|
N
|
D:ASP158
|
4.5
|
15.3
|
1.0
|
|
O
|
D:ASN162
|
4.5
|
28.5
|
1.0
|
|
CA
|
D:ASN162
|
4.6
|
20.3
|
1.0
|
|
CA
|
D:PRO160
|
4.6
|
11.9
|
1.0
|
|
N
|
D:PRO160
|
4.6
|
12.1
|
1.0
|
|
CA
|
D:GLY159
|
4.6
|
12.0
|
1.0
|
|
OD2
|
D:ASP158
|
4.7
|
16.8
|
1.0
|
|
CB
|
D:VAL163
|
4.7
|
19.1
|
1.0
|
|
CB
|
D:ASN162
|
4.7
|
22.1
|
1.0
|
|
O
|
D:PRO160
|
4.7
|
12.8
|
1.0
|
|
OD1
|
D:ASP181
|
4.8
|
12.2
|
1.0
|
|
CA
|
D:ASP158
|
4.8
|
13.2
|
1.0
|
|
O
|
D:ASP158
|
5.0
|
14.3
|
1.0
|
|
CB
|
D:ASP158
|
5.0
|
15.2
|
1.0
|
|
Reference:
A.G.Pavlovsky,
M.G.Williams,
Q.-Z.Ye,
D.F.Ortwine,
C.F.Purchase Ii,
A.D.White,
V.Dhanaraj,
B.D.Roth,
L.L.Johnson,
D.J.Hupe,
C.Humblet,
T.L.Blundell.
X-Ray Structure of Human Stromelysin Catalytic Domain Complexed with Nonpeptide Inhibitors: Implications For Inhibitor Selectivity Protein Sci. V. 8 1455 1999.
ISSN: ISSN 0961-8368
PubMed: 10422833
Page generated: Sat Dec 12 03:16:40 2020
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