Calcium in PDB 1qu0: Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain

The structure of Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain, PDB code: 1qu0 was solved by E.Hohenester, D.Tisi, J.F.Talts, R.Timpl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.35
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.220, 112.890, 117.400, 90.00, 92.00, 90.00
R / Rfree (%)	22.9 / 25.5

The binding sites of Calcium atom in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain (pdb code 1qu0). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain, PDB code: 1qu0:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca701 b:22.5 occ:1.00 O A:SER3053 2.4 17.6 1.0 O2 A:SO4801 2.5 24.5 1.0 O A:HOH975 2.6 33.9 1.0 OD2 A:ASP2982 2.7 14.9 1.0 O A:ASN2999 2.8 13.2 1.0 OD2 A:ASP3055 2.9 16.8 1.0 O4 A:SO4801 3.4 25.6 1.0 S A:SO4801 3.5 25.0 1.0 C A:SER3053 3.5 15.4 1.0 C A:ASN2999 3.8 15.0 1.0 CG A:ASP2982 3.8 16.6 1.0 CG A:ASP3055 3.8 17.2 1.0 OD1 A:ASP2982 4.1 18.2 1.0 N A:ASP3055 4.2 16.6 1.0 CA A:SER3053 4.3 16.2 1.0 O1 A:SO4801 4.3 23.4 1.0 N A:SER3053 4.3 16.7 1.0 CB A:SER3053 4.4 16.4 1.0 CB A:ASP3055 4.4 14.4 1.0 N A:ALA3054 4.5 14.0 1.0 CA A:ASN2999 4.5 13.9 1.0 O3 A:SO4801 4.6 31.7 1.0 CA A:ALA3054 4.7 14.4 1.0 N A:GLY3000 4.7 16.6 1.0 OD1 A:ASP3055 4.7 21.9 1.0 CA A:GLY3000 4.8 18.1 1.0 CB A:ASN2999 4.8 12.5 1.0 C A:ALA3054 4.9 15.1 1.0 CA A:ASP3055 4.9 16.4 1.0 CB A:SER3051 5.0 20.9 1.0

Calcium binding site 2 out of 4 in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca702 b:20.8 occ:1.00 O2 B:SO4803 2.2 17.0 1.0 O B:SER3053 2.4 5.3 1.0 OD2 B:ASP2982 2.4 16.5 1.0 O B:ASN2999 2.6 10.3 1.0 O B:HOH1035 2.9 14.2 1.0 OD2 B:ASP3055 3.0 11.8 1.0 CG B:ASP2982 3.5 15.9 1.0 C B:ASN2999 3.5 11.2 1.0 C B:SER3053 3.6 7.7 1.0 S B:SO4803 3.7 16.6 1.0 OD1 B:ASP2982 3.8 15.0 1.0 CG B:ASP3055 4.0 13.0 1.0 N B:ASP3055 4.1 11.8 1.0 O3 B:SO4803 4.2 21.8 1.0 CA B:ASN2999 4.3 11.8 1.0 O1 B:SO4803 4.4 23.9 1.0 N B:GLY3000 4.4 12.8 1.0 CA B:SER3053 4.4 9.5 1.0 CB B:ASP3055 4.5 11.4 1.0 O4 B:SO4803 4.5 16.1 1.0 N B:ALA3054 4.5 8.4 1.0 CA B:GLY3000 4.5 12.9 1.0 CA B:ALA3054 4.6 9.2 1.0 N B:SER3053 4.6 12.1 1.0 CB B:SER3053 4.6 10.1 1.0 CB B:ASN2999 4.7 10.3 1.0 CB B:ASP2982 4.8 16.2 1.0 C B:ALA3054 4.9 10.4 1.0 CA B:ASP3055 5.0 12.6 1.0 OD1 B:ASP3055 5.0 17.4 1.0

Calcium binding site 3 out of 4 in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca703 b:21.5 occ:1.00 O2 C:SO4804 2.4 18.6 1.0 O C:HOH1164 2.5 31.9 1.0 O C:SER3053 2.5 10.4 1.0 OD2 C:ASP2982 2.6 12.1 1.0 O C:ASN2999 2.8 10.3 1.0 OD2 C:ASP3055 2.8 11.1 1.0 O C:HOH1133 3.1 17.3 1.0 C C:SER3053 3.6 10.6 1.0 S C:SO4804 3.6 20.4 1.0 CG C:ASP2982 3.6 13.1 1.0 C C:ASN2999 3.7 12.6 1.0 CG C:ASP3055 3.8 12.2 1.0 O4 C:SO4804 3.9 20.1 1.0 OD1 C:ASP2982 3.9 14.1 1.0 N C:ASP3055 4.2 13.6 1.0 O1 C:SO4804 4.2 20.1 1.0 CA C:SER3053 4.4 11.1 1.0 CB C:ASP3055 4.4 11.1 1.0 CA C:ASN2999 4.4 12.4 1.0 N C:SER3053 4.4 12.0 1.0 CB C:SER3053 4.5 12.5 1.0 N C:GLY3000 4.5 14.7 1.0 N C:ALA3054 4.6 10.8 1.0 CA C:GLY3000 4.7 16.5 1.0 CB C:ASN2999 4.7 12.4 1.0 CA C:ALA3054 4.8 11.3 1.0 O3 C:SO4804 4.8 24.7 1.0 OD1 C:ASP3055 4.8 13.8 1.0 CB C:ASP2982 5.0 13.6 1.0 CA C:ASP3055 5.0 13.5 1.0

Calcium binding site 4 out of 4 in the Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of the Fifth Laminin G-Like Module of the Mouse Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca704 b:24.1 occ:1.00 O2 D:SO4806 2.5 38.8 1.0 O D:SER3053 2.5 15.8 1.0 OD2 D:ASP2982 2.7 20.6 1.0 OD2 D:ASP3055 2.9 11.1 1.0 O D:ASN2999 3.0 15.2 1.0 O4 D:SO4806 3.4 38.3 1.0 S D:SO4806 3.5 37.1 1.0 C D:SER3053 3.6 16.2 1.0 CG D:ASP2982 3.7 21.6 1.0 C D:ASN2999 3.8 14.5 1.0 CG D:ASP3055 3.9 15.2 1.0 OD1 D:ASP2982 4.0 21.3 1.0 O1 D:SO4806 4.3 34.1 1.0 N D:ASP3055 4.3 15.9 1.0 CA D:SER3053 4.4 17.8 1.0 N D:SER3053 4.4 19.5 1.0 CB D:ASP3055 4.5 13.9 1.0 CB D:SER3053 4.5 16.7 1.0 CA D:ASN2999 4.6 13.2 1.0 N D:ALA3054 4.6 16.4 1.0 O3 D:SO4806 4.6 41.6 1.0 N D:GLY3000 4.7 16.2 1.0 CA D:GLY3000 4.8 17.5 1.0 CA D:ALA3054 4.8 16.0 1.0 OD1 D:ASP3055 4.8 16.7 1.0 CB D:ASN2999 4.8 10.0 1.0

E.Hohenester, D.Tisi, J.F.Talts, R.Timpl. The Crystal Structure of A Laminin G-Like Module Reveals the Molecular Basis of Alpha-Dystroglycan Binding to Laminins, Perlecan, and Agrin. Mol.Cell V. 4 783 1999.
ISSN: ISSN 1097-2765
PubMed: 10619025
DOI: 10.1016/S1097-2765(00)80388-3