Calcium in PDB 1rfn: Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine

The structure of Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine, PDB code: 1rfn was solved by K.-P.Hopfner, A.Lang, A.Karcher, K.Sichler, E.Kopetzki, H.Brandstetter, R.Huber, W.Bode, R.A.Engh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.80
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	90.900, 90.900, 151.600, 90.00, 90.00, 120.00
R / Rfree (%)	21.6 / 27.3

The binding sites of Calcium atom in the Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine (pdb code 1rfn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine, PDB code: 1rfn:

Calcium binding site 1 out of 1 in the Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Coagulation Factor Ixa in Complex with P-Amino Benzamidine within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca500 b:24.1 occ:1.00 OE1 A:GLU77 2.2 29.7 1.0 O A:ASN72 2.4 22.8 1.0 O A:GLU75 2.4 37.3 1.0 OE2 A:GLU70 3.0 27.9 1.0 OE1 A:GLU70 3.0 27.4 1.0 OE2 A:GLU80 3.2 42.4 1.0 CD A:GLU80 3.3 37.3 1.0 CD A:GLU77 3.3 30.5 1.0 CD A:GLU70 3.3 25.9 1.0 C A:ASN72 3.5 24.4 1.0 C A:GLU75 3.5 34.5 1.0 OE1 A:GLU80 3.7 37.1 1.0 CG A:GLU80 3.7 33.4 1.0 OE2 A:GLU77 3.7 31.5 1.0 N A:GLU77 4.0 32.2 1.0 N A:ASN72 4.0 21.7 1.0 CA A:THR76 4.2 32.3 1.0 N A:THR76 4.3 32.8 1.0 CA A:ASN72 4.3 23.3 1.0 N A:ILE73 4.4 26.1 1.0 N A:GLU75 4.5 32.0 1.0 N A:HIS71 4.5 19.9 1.0 CA A:GLU75 4.5 34.4 1.0 CG A:GLU77 4.5 31.4 1.0 CA A:ILE73 4.6 28.3 1.0 C A:THR76 4.6 32.4 1.0 CB A:ASN72 4.7 24.1 1.0 CG A:GLU70 4.7 25.1 1.0 CB A:GLU77 4.7 32.1 1.0 C A:ILE73 4.7 30.9 1.0 C A:HIS71 4.9 19.3 1.0 CA A:GLU77 5.0 32.8 1.0 N A:GLU74 5.0 33.6 1.0

K.P.Hopfner, A.Lang, A.Karcher, K.Sichler, E.Kopetzki, H.Brandstetter, R.Huber, W.Bode, R.A.Engh. Coagulation Factor Ixa: the Relaxed Conformation of TYR99 Blocks Substrate Binding. Structure Fold.Des. V. 7 989 1999.
ISSN: ISSN 0969-2126
PubMed: 10467148
DOI: 10.1016/S0969-2126(99)80125-7