Calcium in PDB 1s6c: Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30

The structure of Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30, PDB code: 1s6c was solved by W.Zhou, Y.Qian, K.Kunjilwar, P.J.Pfaffinger, S.Choe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.79 / 2.00
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	74.744, 74.487, 85.410, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 24.5

The structure of Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30 also contains other interesting chemical elements:

Arsenic

(As)

2 atoms

The binding sites of Calcium atom in the Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30 (pdb code 1s6c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30, PDB code: 1s6c:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca217 b:35.8 occ:1.00 O A:TYR141 2.2 29.8 1.0 OD1 A:ASP139 2.3 43.4 1.0 OE1 A:GLU146 2.3 36.7 1.0 OD1 A:ASN137 2.3 40.8 1.0 OD1 A:ASP135 2.4 36.0 1.0 O A:HOH298 2.5 34.7 1.0 OE2 A:GLU146 2.8 51.2 1.0 CD A:GLU146 2.9 48.9 1.0 CG A:ASP139 3.1 41.6 1.0 C A:TYR141 3.3 25.7 1.0 CG A:ASN137 3.4 46.6 1.0 OD2 A:ASP139 3.4 48.1 1.0 CG A:ASP135 3.5 36.6 1.0 N A:TYR141 4.1 28.5 1.0 ND2 A:ASN137 4.1 44.2 1.0 N A:ASP139 4.2 31.3 1.0 CA A:TYR141 4.2 25.9 1.0 N A:ILE142 4.3 30.3 1.0 CA A:ASP135 4.3 33.0 1.0 N A:ASN137 4.3 45.2 1.0 CA A:ILE142 4.3 28.6 1.0 OD2 A:ASP135 4.3 31.5 1.0 CG A:GLU146 4.4 41.0 1.0 CB A:ASP135 4.4 28.5 1.0 CB A:ASP139 4.4 32.0 1.0 CB A:TYR141 4.4 33.7 1.0 C A:ASP135 4.5 37.1 1.0 CB A:ASN137 4.6 38.4 1.0 N A:LYS138 4.6 40.3 1.0 N A:ILE136 4.6 39.6 1.0 CA A:ASP139 4.8 34.6 1.0 CA A:ASN137 4.8 37.6 1.0 C A:ASN137 4.8 40.4 1.0 N A:GLY140 4.9 37.1 1.0 N A:ASN143 4.9 29.3 1.0 ND2 A:ASN143 4.9 52.8 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Complex Between KCHIP1 and KV4.2 N1-30 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca218 b:30.8 occ:1.00 OD1 A:ASP183 2.1 28.5 1.0 O A:ILE189 2.2 33.9 1.0 O A:HOH301 2.2 34.7 1.0 OD1 A:ASN185 2.3 38.7 1.0 OD1 A:ASP187 2.4 42.0 1.0 OE1 A:GLU194 2.4 28.4 1.0 OE2 A:GLU194 2.6 30.3 1.0 CD A:GLU194 2.8 32.1 1.0 CG A:ASP183 3.3 25.8 1.0 CG A:ASN185 3.4 41.8 1.0 C A:ILE189 3.4 34.2 1.0 CG A:ASP187 3.5 48.3 1.0 ND2 A:ASN185 4.0 42.9 1.0 OD2 A:ASP187 4.1 45.3 1.0 OD2 A:ASP183 4.1 35.9 1.0 N A:ILE189 4.2 28.3 1.0 CA A:ASP183 4.2 32.3 1.0 N A:ASP187 4.3 42.3 1.0 CB A:ASP183 4.3 31.4 1.0 CG1 A:ILE189 4.3 43.4 1.0 N A:ASN185 4.3 37.6 1.0 N A:VAL190 4.3 34.4 1.0 CA A:ILE189 4.3 34.8 1.0 CG A:GLU194 4.4 30.4 1.0 CA A:VAL190 4.4 30.8 1.0 O A:HOH352 4.4 51.1 1.0 C A:ASP183 4.5 37.9 1.0 CB A:ASN185 4.6 40.7 1.0 N A:LYS184 4.6 36.9 1.0 N A:LYS186 4.7 43.8 1.0 CB A:ASP187 4.7 36.8 1.0 O A:HOH227 4.7 40.1 1.0 N A:THR191 4.8 26.3 1.0 CA A:ASN185 4.8 42.9 1.0 C A:ASN185 4.8 48.3 1.0 CA A:ASP187 4.8 35.4 1.0 CB A:ILE189 4.9 30.9 1.0 N A:GLY188 4.9 31.4 1.0 C A:ASP187 5.0 33.8 1.0

W.Zhou, Y.Qian, K.Kunjilwar, P.J.Pfaffinger, S.Choe. Structural Insights Into the Functional Interaction of KCHIP1 with Shal-Type K(+) Channels. Neuron V. 41 573 2004.
ISSN: ISSN 0896-6273
PubMed: 14980206
DOI: 10.1016/S0896-6273(04)00045-5