Calcium in PDB 1t5s: Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form

All present enzymatic activity of Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form:
3.6.3.8;

The structure of Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form, PDB code: 1t5s was solved by T.L.-M.Sorensen, J.V.Moller, P.Nissen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	162.439, 76.259, 151.164, 90.00, 108.70, 90.00
R / Rfree (%)	24.2 / 28.5

The structure of Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Potassium	(K)	1 atom

The binding sites of Calcium atom in the Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form (pdb code 1t5s). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form, PDB code: 1t5s:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1003 b:85.9 occ:1.00 OD1 A:ASN796 2.3 86.2 1.0 O A:ALA305 2.3 94.8 1.0 OD2 A:ASP800 2.4 73.8 1.0 OE2 A:GLU309 2.4 97.0 1.0 O A:ILE307 2.5 96.8 1.0 O A:VAL304 2.6 94.5 1.0 OE1 A:GLU309 2.7 94.3 1.0 CD A:GLU309 2.9 95.8 1.0 C A:ALA305 3.2 94.8 1.0 CG A:ASP800 3.3 75.8 1.0 CG A:ASN796 3.4 84.2 1.0 C A:ILE307 3.6 96.1 1.0 O A:HOH1045 3.7 69.1 1.0 CB A:ASP800 3.7 76.8 1.0 CA A:ALA305 3.7 94.8 1.0 C A:VAL304 3.7 94.5 1.0 ND2 A:ASN768 3.7 91.6 1.0 ND2 A:ASN796 3.9 84.3 1.0 N A:ILE307 4.1 95.6 1.0 N A:ALA305 4.2 94.5 1.0 C A:ALA306 4.2 95.3 1.0 N A:ALA306 4.2 95.1 1.0 CA A:ILE307 4.4 96.0 1.0 CG A:GLU309 4.4 94.3 1.0 OD1 A:ASP800 4.4 75.3 1.0 O A:ALA306 4.5 95.2 1.0 N A:GLU309 4.5 94.3 1.0 N A:PRO308 4.5 96.0 1.0 CB A:ASN796 4.6 84.3 1.0 CA A:ALA306 4.6 95.2 1.0 CA A:PRO308 4.7 95.6 1.0 CB A:ILE307 4.9 96.1 1.0 CG A:ASN768 4.9 92.9 1.0

Calcium binding site 2 out of 2 in the Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the (Sr)CA2+-Atpase CA2-E1-Amppcp Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1004 b:83.7 occ:1.00 O A:HOH1045 2.2 69.1 1.0 OE2 A:GLU771 2.4 98.1 1.0 OD1 A:ASP800 2.4 75.3 1.0 OD1 A:ASN768 2.4 90.9 1.0 OG1 A:THR799 2.5 78.5 1.0 OE2 A:GLU908 2.5 89.3 1.0 CD A:GLU771 3.2 99.7 1.0 CG A:ASP800 3.2 75.8 1.0 CD A:GLU908 3.3 89.7 1.0 CB A:THR799 3.4 79.0 1.0 OE1 A:GLU908 3.4 88.1 1.0 CG A:ASN768 3.5 92.9 1.0 OD2 A:ASP800 3.5 73.8 1.0 OE1 A:GLU771 3.6 0.3 1.0 ND2 A:ASN768 3.9 91.6 1.0 C A:THR799 4.3 78.5 1.0 N A:ASP800 4.4 77.8 1.0 CG2 A:THR799 4.4 78.6 1.0 O A:VAL795 4.4 84.0 1.0 CB A:ASP800 4.4 76.8 1.0 CG A:GLU771 4.4 0.3 1.0 CA A:THR799 4.5 79.1 1.0 CB A:SER767 4.7 94.0 1.0 CB A:ASN768 4.7 94.1 1.0 O A:ALA305 4.7 94.8 1.0 O A:THR799 4.7 79.0 1.0 CG A:GLU908 4.8 91.2 1.0 CA A:ASP800 4.8 77.2 1.0 N A:ASN768 4.8 94.3 1.0 CA A:ASN768 4.8 94.4 1.0 CA A:ASN796 4.9 84.2 1.0 C A:VAL795 5.0 84.0 1.0

T.L.-M.Sorensen, J.V.Moller, P.Nissen. Phosphoryl Transfer and Calcium Ion Occlusion in the Calcium Pump. Science V. 304 1672 2004.
ISSN: ISSN 0036-8075
PubMed: 15192230
DOI: 10.1126/SCIENCE.1099366