Calcium in PDB 1tad: Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-

The structure of Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-, PDB code: 1tad was solved by J.Sondek, D.G.Lambright, J.P.Noel, H.E.Hamm, P.B.Sigler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 1.70
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	74.900, 108.200, 79.000, 90.00, 111.70, 90.00
R / Rfree (%)	20.9 / 26.6

The structure of Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4- also contains other interesting chemical elements:

Fluorine	(F)	12 atoms
Aluminium	(Al)	3 atoms
Arsenic	(As)	6 atoms

The binding sites of Calcium atom in the Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4- (pdb code 1tad). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-, PDB code: 1tad:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4- within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca352 b:13.4 occ:1.00 F2 A:ALF355 2.3 11.4 1.0 O2B A:GDP351 2.4 8.5 1.0 OG1 A:THR177 2.4 10.2 1.0 O A:HOH401 2.5 8.0 1.0 O A:HOH402 2.5 9.5 1.0 F4 A:ALF355 2.5 11.5 1.0 OG A:SER43 2.5 12.6 1.0 AL A:ALF355 3.3 10.3 1.0 O3B A:GDP351 3.4 9.0 1.0 PB A:GDP351 3.4 9.7 1.0 CB A:SER43 3.5 9.7 1.0 CB A:THR177 3.6 12.0 1.0 CG2 A:THR177 3.9 14.0 1.0 N A:THR177 4.1 11.2 1.0 N A:SER43 4.1 8.2 1.0 O A:HOH400 4.2 9.8 1.0 CA A:SER43 4.3 9.4 1.0 CA A:THR177 4.4 11.5 1.0 O3A A:GDP351 4.5 11.5 1.0 O A:HOH444 4.5 20.4 1.0 O1B A:GDP351 4.5 9.8 1.0 O2A A:GDP351 4.5 8.0 1.0 O A:VAL175 4.6 13.7 1.0 OD2 A:ASP196 4.6 15.1 1.0 F3 A:ALF355 4.6 10.0 1.0 O A:VAL197 4.7 14.1 1.0 O A:THR177 4.7 14.3 1.0 F1 A:ALF355 4.8 10.2 1.0 CE A:LYS42 4.8 8.8 1.0 NH1 A:ARG174 4.8 6.9 1.0 O A:HOH1095 4.8 16.2 1.0 O A:HOH677 4.9 16.7 1.0 PA A:GDP351 4.9 9.4 1.0 C A:THR177 4.9 13.0 1.0 CB A:LYS42 4.9 8.6 1.0

Calcium binding site 2 out of 3 in the Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4- within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca352 b:16.9 occ:1.00 O2B B:GDP351 2.3 9.4 1.0 OG B:SER43 2.4 13.4 1.0 F4 B:ALF355 2.4 11.6 1.0 F2 B:ALF355 2.5 14.1 1.0 OG1 B:THR177 2.5 13.6 1.0 O B:HOH405 2.5 11.1 1.0 O B:HOH404 2.6 11.7 1.0 AL B:ALF355 3.3 11.6 1.0 PB B:GDP351 3.4 10.9 1.0 O3B B:GDP351 3.4 10.8 1.0 CB B:SER43 3.4 10.5 1.0 CB B:THR177 3.7 14.4 1.0 CG2 B:THR177 3.8 13.4 1.0 N B:SER43 4.0 11.1 1.0 N B:THR177 4.0 16.0 1.0 O B:HOH403 4.2 12.4 1.0 CA B:SER43 4.3 10.1 1.0 CA B:THR177 4.4 16.2 1.0 O B:HOH839 4.4 19.4 1.0 O1B B:GDP351 4.4 12.9 1.0 O3A B:GDP351 4.5 14.9 1.0 O2A B:GDP351 4.5 13.5 1.0 O B:VAL197 4.6 15.6 1.0 O B:VAL175 4.6 17.9 1.0 O B:THR177 4.6 16.8 1.0 OD2 B:ASP196 4.6 20.7 1.0 F1 B:ALF355 4.7 14.0 1.0 F3 B:ALF355 4.7 13.9 1.0 O B:HOH809 4.8 16.4 1.0 O B:HOH805 4.8 22.1 1.0 NH1 B:ARG174 4.8 10.3 1.0 CB B:LYS42 4.8 11.5 1.0 CE B:LYS42 4.8 12.5 1.0 PA B:GDP351 4.8 12.3 1.0 C B:THR177 4.8 17.2 1.0 O1A B:GDP351 5.0 10.9 1.0

Calcium binding site 3 out of 3 in the Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4-


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Gtpase Mechanism of Gproteins From the 1.7-Angstrom Crystal Structure of Transducin Alpha-Gdp-ALF4- within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca352 b:12.3 occ:1.00 F1 C:ALF355 2.4 12.3 1.0 O2B C:GDP351 2.4 7.7 1.0 OG1 C:THR177 2.5 15.5 1.0 F3 C:ALF355 2.5 13.8 1.0 OG C:SER43 2.5 11.1 1.0 O C:HOH408 2.6 7.3 1.0 O C:HOH407 2.6 11.6 1.0 AL C:ALF355 3.3 12.3 1.0 CB C:SER43 3.4 10.1 1.0 PB C:GDP351 3.5 9.6 1.0 O3B C:GDP351 3.5 11.9 1.0 CB C:THR177 3.7 16.2 1.0 CG2 C:THR177 3.9 16.5 1.0 N C:THR177 4.0 14.9 1.0 N C:SER43 4.1 8.5 1.0 O C:HOH406 4.2 10.9 1.0 CA C:SER43 4.3 7.1 1.0 CA C:THR177 4.4 15.6 1.0 O2A C:GDP351 4.4 10.0 1.0 O C:HOH918 4.5 23.8 1.0 O1B C:GDP351 4.5 10.3 1.0 O3A C:GDP351 4.5 12.1 1.0 O C:THR177 4.6 15.7 1.0 OD2 C:ASP196 4.6 19.6 1.0 O C:VAL197 4.6 11.6 1.0 O C:VAL175 4.6 17.8 1.0 F4 C:ALF355 4.6 11.9 1.0 NH1 C:ARG174 4.6 13.7 1.0 O C:HOH1178 4.7 12.9 1.0 F2 C:ALF355 4.7 12.5 1.0 CE C:LYS42 4.8 8.4 1.0 C C:THR177 4.8 16.3 1.0 PA C:GDP351 4.9 9.9 1.0 O C:HOH895 4.9 17.8 1.0 CB C:LYS42 5.0 9.7 1.0

J.Sondek, D.G.Lambright, J.P.Noel, H.E.Hamm, P.B.Sigler. Gtpase Mechanism of Gproteins From the 1.7-A Crystal Structure of Transducin Alpha-Gdp-Aif-4. Nature V. 372 276 1994.
ISSN: ISSN 0028-0836
PubMed: 7969474
DOI: 10.1038/372276A0