Calcium in PDB 1tzo: Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
Protein crystallography data
The structure of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore, PDB code: 1tzo
was solved by
D.B.Lacy,
D.J.Wigelsworth,
R.A.Melnyk,
R.J.Collier,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
30.00 /
3.60
|
|
Space group
|
P 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
149.608,
167.028,
168.200,
77.56,
75.74,
76.01
|
|
R / Rfree (%)
|
31.4 /
31.7
|
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
20;
Page 3, Binding sites: 21 -
28;
Binding sites:
The binding sites of Calcium atom in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
(pdb code 1tzo). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 28 binding sites of Calcium where determined in the
Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore, PDB code: 1tzo:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 1 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca736
b:33.7
occ:1.00
|
OD1
|
A:ASP179
|
2.2
|
38.9
|
1.0
|
|
OD2
|
A:ASP179
|
2.2
|
37.7
|
1.0
|
|
O
|
A:ILE183
|
2.2
|
8.1
|
1.0
|
|
OE2
|
A:GLU188
|
2.4
|
13.5
|
1.0
|
|
OD1
|
A:ASP177
|
2.4
|
19.9
|
1.0
|
|
CG
|
A:ASP179
|
2.5
|
37.9
|
1.0
|
|
OD2
|
A:ASP181
|
2.7
|
20.9
|
1.0
|
|
OD1
|
A:ASP181
|
2.7
|
20.0
|
1.0
|
|
CG
|
A:ASP181
|
3.0
|
20.7
|
1.0
|
|
C
|
A:ILE183
|
3.4
|
8.3
|
1.0
|
|
CD
|
A:GLU188
|
3.5
|
13.1
|
1.0
|
|
CG
|
A:ASP177
|
3.6
|
21.3
|
1.0
|
|
O
|
A:PRO223
|
3.8
|
14.6
|
1.0
|
|
CB
|
A:ASP179
|
4.0
|
38.3
|
1.0
|
|
CA
|
A:CA737
|
4.0
|
18.9
|
1.0
|
|
CA
|
A:PRO223
|
4.1
|
11.3
|
1.0
|
|
OD2
|
A:ASP177
|
4.2
|
20.6
|
1.0
|
|
OE1
|
A:GLU188
|
4.2
|
13.3
|
1.0
|
|
CA
|
A:ILE183
|
4.2
|
7.8
|
1.0
|
|
CB
|
A:ILE183
|
4.2
|
9.6
|
1.0
|
|
N
|
A:ILE183
|
4.2
|
11.1
|
1.0
|
|
OD1
|
A:ASP185
|
4.2
|
55.9
|
1.0
|
|
CB
|
A:GLU188
|
4.3
|
16.5
|
1.0
|
|
C
|
A:PRO223
|
4.3
|
13.3
|
1.0
|
|
C
|
A:PRO184
|
4.4
|
21.2
|
1.0
|
|
CB
|
A:ASP181
|
4.4
|
20.5
|
1.0
|
|
CG2
|
A:ILE183
|
4.4
|
10.6
|
1.0
|
|
CG
|
A:GLU188
|
4.4
|
14.3
|
1.0
|
|
N
|
A:ASP185
|
4.4
|
9.6
|
1.0
|
|
N
|
A:PRO184
|
4.4
|
17.9
|
1.0
|
|
N
|
A:ASP179
|
4.5
|
60.5
|
1.0
|
|
N
|
A:ASP181
|
4.5
|
22.6
|
1.0
|
|
CA
|
A:PRO184
|
4.6
|
19.1
|
1.0
|
|
CA
|
A:ASP177
|
4.7
|
39.3
|
1.0
|
|
O
|
A:PRO184
|
4.7
|
20.8
|
1.0
|
|
CB
|
A:ASP177
|
4.7
|
24.4
|
1.0
|
|
CA
|
A:ASP179
|
4.7
|
54.9
|
1.0
|
|
CB
|
A:PRO223
|
4.7
|
35.8
|
1.0
|
|
N
|
A:GLY182
|
4.8
|
38.5
|
1.0
|
|
N
|
A:ASN180
|
4.8
|
43.0
|
1.0
|
|
CA
|
A:ASP185
|
4.8
|
12.6
|
1.0
|
|
O
|
A:SER222
|
4.8
|
6.2
|
1.0
|
|
CA
|
A:ASP181
|
5.0
|
18.8
|
1.0
|
|
N
|
A:ARG178
|
5.0
|
58.5
|
1.0
|
|
C
|
A:ASP177
|
5.0
|
37.2
|
1.0
|
|
Calcium binding site 2 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 2 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca737
b:18.9
occ:1.00
|
O
|
A:LYS225
|
2.0
|
64.4
|
1.0
|
|
OE1
|
A:GLU188
|
2.3
|
13.3
|
1.0
|
|
O
|
A:SER222
|
2.3
|
6.2
|
1.0
|
|
OD2
|
A:ASP179
|
2.4
|
37.7
|
1.0
|
|
OD2
|
A:ASP181
|
2.5
|
20.9
|
1.0
|
|
OD2
|
A:ASP235
|
2.8
|
38.6
|
1.0
|
|
CD
|
A:GLU188
|
3.0
|
13.1
|
1.0
|
|
CG
|
A:ASP179
|
3.1
|
37.9
|
1.0
|
|
C
|
A:LYS225
|
3.2
|
64.1
|
1.0
|
|
OE2
|
A:GLU188
|
3.3
|
13.5
|
1.0
|
|
CB
|
A:ASP179
|
3.4
|
38.3
|
1.0
|
|
C
|
A:SER222
|
3.5
|
6.9
|
1.0
|
|
CG
|
A:ASP181
|
3.7
|
20.7
|
1.0
|
|
N
|
A:LYS225
|
3.7
|
61.6
|
1.0
|
|
O
|
A:TRP226
|
3.9
|
52.8
|
1.0
|
|
CG
|
A:ASP235
|
3.9
|
36.7
|
1.0
|
|
CA
|
A:CA736
|
4.0
|
33.7
|
1.0
|
|
OD1
|
A:ASP179
|
4.0
|
38.9
|
1.0
|
|
CA
|
A:LYS225
|
4.0
|
63.9
|
1.0
|
|
C
|
A:PRO223
|
4.0
|
13.3
|
1.0
|
|
CA
|
A:PRO223
|
4.1
|
11.3
|
1.0
|
|
CG
|
A:GLU188
|
4.1
|
14.3
|
1.0
|
|
N
|
A:TRP226
|
4.2
|
54.8
|
1.0
|
|
O
|
A:PRO223
|
4.2
|
14.6
|
1.0
|
|
N
|
A:PRO223
|
4.2
|
10.4
|
1.0
|
|
C
|
A:TRP226
|
4.3
|
52.6
|
1.0
|
|
CA
|
A:TRP226
|
4.4
|
53.9
|
1.0
|
|
CB
|
A:ASP181
|
4.4
|
20.5
|
1.0
|
|
N
|
A:GLU224
|
4.5
|
6.3
|
1.0
|
|
CB
|
A:ASP235
|
4.5
|
32.9
|
1.0
|
|
OG1
|
A:THR228
|
4.6
|
16.8
|
1.0
|
|
CA
|
A:SER222
|
4.6
|
7.1
|
1.0
|
|
OD1
|
A:ASP181
|
4.7
|
20.0
|
1.0
|
|
CB
|
A:LYS225
|
4.7
|
45.8
|
1.0
|
|
N
|
A:SER222
|
4.7
|
7.7
|
1.0
|
|
C
|
A:GLU224
|
4.7
|
12.7
|
1.0
|
|
OG
|
A:SER221
|
5.0
|
12.3
|
1.0
|
|
OD1
|
A:ASP235
|
5.0
|
37.9
|
1.0
|
|
CA
|
A:ASP179
|
5.0
|
54.9
|
1.0
|
|
Calcium binding site 3 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 3 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca736
b:33.7
occ:1.00
|
OD1
|
B:ASP179
|
2.2
|
38.9
|
1.0
|
|
OD2
|
B:ASP179
|
2.2
|
37.7
|
1.0
|
|
O
|
B:ILE183
|
2.2
|
8.1
|
1.0
|
|
OE2
|
B:GLU188
|
2.4
|
13.5
|
1.0
|
|
OD1
|
B:ASP177
|
2.4
|
19.9
|
1.0
|
|
CG
|
B:ASP179
|
2.5
|
37.9
|
1.0
|
|
OD2
|
B:ASP181
|
2.7
|
20.9
|
1.0
|
|
OD1
|
B:ASP181
|
2.7
|
20.0
|
1.0
|
|
CG
|
B:ASP181
|
3.0
|
20.7
|
1.0
|
|
C
|
B:ILE183
|
3.4
|
8.3
|
1.0
|
|
CD
|
B:GLU188
|
3.5
|
13.1
|
1.0
|
|
CG
|
B:ASP177
|
3.6
|
21.3
|
1.0
|
|
O
|
B:PRO223
|
3.8
|
14.6
|
1.0
|
|
CB
|
B:ASP179
|
4.0
|
38.3
|
1.0
|
|
CA
|
B:CA737
|
4.0
|
18.9
|
1.0
|
|
CA
|
B:PRO223
|
4.1
|
11.3
|
1.0
|
|
OD2
|
B:ASP177
|
4.2
|
20.6
|
1.0
|
|
OE1
|
B:GLU188
|
4.2
|
13.3
|
1.0
|
|
CB
|
B:ILE183
|
4.2
|
9.6
|
1.0
|
|
CA
|
B:ILE183
|
4.2
|
7.8
|
1.0
|
|
N
|
B:ILE183
|
4.2
|
11.1
|
1.0
|
|
OD1
|
B:ASP185
|
4.2
|
55.9
|
1.0
|
|
CB
|
B:GLU188
|
4.3
|
16.5
|
1.0
|
|
C
|
B:PRO223
|
4.3
|
13.3
|
1.0
|
|
C
|
B:PRO184
|
4.4
|
21.2
|
1.0
|
|
CB
|
B:ASP181
|
4.4
|
20.5
|
1.0
|
|
CG2
|
B:ILE183
|
4.4
|
10.6
|
1.0
|
|
CG
|
B:GLU188
|
4.4
|
14.3
|
1.0
|
|
N
|
B:ASP185
|
4.4
|
9.6
|
1.0
|
|
N
|
B:PRO184
|
4.4
|
17.9
|
1.0
|
|
N
|
B:ASP179
|
4.5
|
60.5
|
1.0
|
|
N
|
B:ASP181
|
4.5
|
22.6
|
1.0
|
|
CA
|
B:PRO184
|
4.6
|
19.1
|
1.0
|
|
CA
|
B:ASP177
|
4.7
|
39.3
|
1.0
|
|
O
|
B:PRO184
|
4.7
|
20.8
|
1.0
|
|
CB
|
B:ASP177
|
4.7
|
24.4
|
1.0
|
|
CA
|
B:ASP179
|
4.7
|
54.9
|
1.0
|
|
CB
|
B:PRO223
|
4.7
|
35.8
|
1.0
|
|
N
|
B:GLY182
|
4.8
|
38.5
|
1.0
|
|
N
|
B:ASN180
|
4.8
|
43.0
|
1.0
|
|
CA
|
B:ASP185
|
4.8
|
12.6
|
1.0
|
|
O
|
B:SER222
|
4.8
|
6.2
|
1.0
|
|
CA
|
B:ASP181
|
5.0
|
18.8
|
1.0
|
|
N
|
B:ARG178
|
5.0
|
58.5
|
1.0
|
|
C
|
B:ASP177
|
5.0
|
37.2
|
1.0
|
|
Calcium binding site 4 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 4 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca737
b:18.9
occ:1.00
|
O
|
B:LYS225
|
2.0
|
64.4
|
1.0
|
|
OE1
|
B:GLU188
|
2.3
|
13.3
|
1.0
|
|
O
|
B:SER222
|
2.3
|
6.2
|
1.0
|
|
OD2
|
B:ASP179
|
2.4
|
37.7
|
1.0
|
|
OD2
|
B:ASP181
|
2.5
|
20.9
|
1.0
|
|
OD2
|
B:ASP235
|
2.8
|
38.6
|
1.0
|
|
CD
|
B:GLU188
|
3.0
|
13.1
|
1.0
|
|
CG
|
B:ASP179
|
3.1
|
37.9
|
1.0
|
|
C
|
B:LYS225
|
3.2
|
64.1
|
1.0
|
|
OE2
|
B:GLU188
|
3.3
|
13.5
|
1.0
|
|
CB
|
B:ASP179
|
3.4
|
38.3
|
1.0
|
|
C
|
B:SER222
|
3.5
|
6.9
|
1.0
|
|
CG
|
B:ASP181
|
3.7
|
20.7
|
1.0
|
|
N
|
B:LYS225
|
3.7
|
61.6
|
1.0
|
|
O
|
B:TRP226
|
3.9
|
52.8
|
1.0
|
|
CG
|
B:ASP235
|
3.9
|
36.7
|
1.0
|
|
CA
|
B:CA736
|
4.0
|
33.7
|
1.0
|
|
OD1
|
B:ASP179
|
4.0
|
38.9
|
1.0
|
|
CA
|
B:LYS225
|
4.0
|
63.9
|
1.0
|
|
C
|
B:PRO223
|
4.0
|
13.3
|
1.0
|
|
CA
|
B:PRO223
|
4.1
|
11.3
|
1.0
|
|
CG
|
B:GLU188
|
4.1
|
14.3
|
1.0
|
|
N
|
B:TRP226
|
4.2
|
54.8
|
1.0
|
|
O
|
B:PRO223
|
4.2
|
14.6
|
1.0
|
|
N
|
B:PRO223
|
4.2
|
10.4
|
1.0
|
|
C
|
B:TRP226
|
4.3
|
52.6
|
1.0
|
|
CA
|
B:TRP226
|
4.4
|
53.9
|
1.0
|
|
CB
|
B:ASP181
|
4.4
|
20.5
|
1.0
|
|
N
|
B:GLU224
|
4.5
|
6.3
|
1.0
|
|
CB
|
B:ASP235
|
4.5
|
32.9
|
1.0
|
|
OG1
|
B:THR228
|
4.6
|
16.8
|
1.0
|
|
CA
|
B:SER222
|
4.6
|
7.1
|
1.0
|
|
OD1
|
B:ASP181
|
4.7
|
20.0
|
1.0
|
|
CB
|
B:LYS225
|
4.7
|
45.8
|
1.0
|
|
N
|
B:SER222
|
4.7
|
7.7
|
1.0
|
|
C
|
B:GLU224
|
4.7
|
12.7
|
1.0
|
|
OG
|
B:SER221
|
5.0
|
12.3
|
1.0
|
|
OD1
|
B:ASP235
|
5.0
|
37.9
|
1.0
|
|
CA
|
B:ASP179
|
5.0
|
54.9
|
1.0
|
|
Calcium binding site 5 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 5 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca736
b:33.7
occ:1.00
|
OD1
|
C:ASP179
|
2.2
|
38.9
|
1.0
|
|
OD2
|
C:ASP179
|
2.2
|
37.7
|
1.0
|
|
O
|
C:ILE183
|
2.2
|
8.1
|
1.0
|
|
OE2
|
C:GLU188
|
2.4
|
13.5
|
1.0
|
|
OD1
|
C:ASP177
|
2.4
|
19.9
|
1.0
|
|
CG
|
C:ASP179
|
2.5
|
37.9
|
1.0
|
|
OD2
|
C:ASP181
|
2.7
|
20.9
|
1.0
|
|
OD1
|
C:ASP181
|
2.7
|
20.0
|
1.0
|
|
CG
|
C:ASP181
|
3.0
|
20.7
|
1.0
|
|
C
|
C:ILE183
|
3.4
|
8.3
|
1.0
|
|
CD
|
C:GLU188
|
3.5
|
13.1
|
1.0
|
|
CG
|
C:ASP177
|
3.6
|
21.3
|
1.0
|
|
O
|
C:PRO223
|
3.8
|
14.6
|
1.0
|
|
CB
|
C:ASP179
|
4.0
|
38.3
|
1.0
|
|
CA
|
C:CA737
|
4.0
|
18.9
|
1.0
|
|
CA
|
C:PRO223
|
4.1
|
11.3
|
1.0
|
|
OD2
|
C:ASP177
|
4.2
|
20.6
|
1.0
|
|
OE1
|
C:GLU188
|
4.2
|
13.3
|
1.0
|
|
CB
|
C:ILE183
|
4.2
|
9.6
|
1.0
|
|
CA
|
C:ILE183
|
4.2
|
7.8
|
1.0
|
|
N
|
C:ILE183
|
4.2
|
11.1
|
1.0
|
|
OD1
|
C:ASP185
|
4.2
|
55.9
|
1.0
|
|
CB
|
C:GLU188
|
4.3
|
16.5
|
1.0
|
|
C
|
C:PRO223
|
4.3
|
13.3
|
1.0
|
|
C
|
C:PRO184
|
4.4
|
21.2
|
1.0
|
|
CB
|
C:ASP181
|
4.4
|
20.5
|
1.0
|
|
CG2
|
C:ILE183
|
4.4
|
10.6
|
1.0
|
|
CG
|
C:GLU188
|
4.4
|
14.3
|
1.0
|
|
N
|
C:ASP185
|
4.4
|
9.6
|
1.0
|
|
N
|
C:PRO184
|
4.4
|
17.9
|
1.0
|
|
N
|
C:ASP179
|
4.5
|
60.5
|
1.0
|
|
N
|
C:ASP181
|
4.5
|
22.6
|
1.0
|
|
CA
|
C:PRO184
|
4.6
|
19.1
|
1.0
|
|
CA
|
C:ASP177
|
4.7
|
39.3
|
1.0
|
|
O
|
C:PRO184
|
4.7
|
20.8
|
1.0
|
|
CB
|
C:ASP177
|
4.7
|
24.4
|
1.0
|
|
CA
|
C:ASP179
|
4.7
|
54.9
|
1.0
|
|
CB
|
C:PRO223
|
4.7
|
35.8
|
1.0
|
|
N
|
C:GLY182
|
4.8
|
38.5
|
1.0
|
|
N
|
C:ASN180
|
4.8
|
43.0
|
1.0
|
|
CA
|
C:ASP185
|
4.8
|
12.6
|
1.0
|
|
O
|
C:SER222
|
4.8
|
6.2
|
1.0
|
|
CA
|
C:ASP181
|
5.0
|
18.8
|
1.0
|
|
N
|
C:ARG178
|
5.0
|
58.5
|
1.0
|
|
C
|
C:ASP177
|
5.0
|
37.2
|
1.0
|
|
Calcium binding site 6 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 6 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca737
b:18.9
occ:1.00
|
O
|
C:LYS225
|
2.0
|
64.4
|
1.0
|
|
OE1
|
C:GLU188
|
2.3
|
13.3
|
1.0
|
|
O
|
C:SER222
|
2.3
|
6.2
|
1.0
|
|
OD2
|
C:ASP179
|
2.4
|
37.7
|
1.0
|
|
OD2
|
C:ASP181
|
2.5
|
20.9
|
1.0
|
|
OD2
|
C:ASP235
|
2.8
|
38.6
|
1.0
|
|
CD
|
C:GLU188
|
3.0
|
13.1
|
1.0
|
|
CG
|
C:ASP179
|
3.1
|
37.9
|
1.0
|
|
C
|
C:LYS225
|
3.2
|
64.1
|
1.0
|
|
OE2
|
C:GLU188
|
3.3
|
13.5
|
1.0
|
|
CB
|
C:ASP179
|
3.4
|
38.3
|
1.0
|
|
C
|
C:SER222
|
3.5
|
6.9
|
1.0
|
|
CG
|
C:ASP181
|
3.7
|
20.7
|
1.0
|
|
N
|
C:LYS225
|
3.7
|
61.6
|
1.0
|
|
O
|
C:TRP226
|
3.9
|
52.8
|
1.0
|
|
CG
|
C:ASP235
|
3.9
|
36.7
|
1.0
|
|
CA
|
C:CA736
|
4.0
|
33.7
|
1.0
|
|
OD1
|
C:ASP179
|
4.0
|
38.9
|
1.0
|
|
CA
|
C:LYS225
|
4.0
|
63.9
|
1.0
|
|
C
|
C:PRO223
|
4.0
|
13.3
|
1.0
|
|
CA
|
C:PRO223
|
4.1
|
11.3
|
1.0
|
|
CG
|
C:GLU188
|
4.1
|
14.3
|
1.0
|
|
N
|
C:TRP226
|
4.2
|
54.8
|
1.0
|
|
O
|
C:PRO223
|
4.2
|
14.6
|
1.0
|
|
N
|
C:PRO223
|
4.2
|
10.4
|
1.0
|
|
C
|
C:TRP226
|
4.3
|
52.6
|
1.0
|
|
CA
|
C:TRP226
|
4.4
|
53.9
|
1.0
|
|
CB
|
C:ASP181
|
4.4
|
20.5
|
1.0
|
|
N
|
C:GLU224
|
4.5
|
6.3
|
1.0
|
|
CB
|
C:ASP235
|
4.5
|
32.9
|
1.0
|
|
OG1
|
C:THR228
|
4.6
|
16.8
|
1.0
|
|
CA
|
C:SER222
|
4.6
|
7.1
|
1.0
|
|
OD1
|
C:ASP181
|
4.7
|
20.0
|
1.0
|
|
CB
|
C:LYS225
|
4.7
|
45.8
|
1.0
|
|
N
|
C:SER222
|
4.7
|
7.7
|
1.0
|
|
C
|
C:GLU224
|
4.7
|
12.7
|
1.0
|
|
OG
|
C:SER221
|
5.0
|
12.3
|
1.0
|
|
OD1
|
C:ASP235
|
5.0
|
37.9
|
1.0
|
|
CA
|
C:ASP179
|
5.0
|
54.9
|
1.0
|
|
Calcium binding site 7 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 7 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca736
b:33.7
occ:1.00
|
OD1
|
D:ASP179
|
2.2
|
38.9
|
1.0
|
|
OD2
|
D:ASP179
|
2.2
|
37.7
|
1.0
|
|
O
|
D:ILE183
|
2.2
|
8.1
|
1.0
|
|
OE2
|
D:GLU188
|
2.4
|
13.5
|
1.0
|
|
OD1
|
D:ASP177
|
2.4
|
19.9
|
1.0
|
|
CG
|
D:ASP179
|
2.5
|
37.9
|
1.0
|
|
OD2
|
D:ASP181
|
2.7
|
20.9
|
1.0
|
|
OD1
|
D:ASP181
|
2.7
|
20.0
|
1.0
|
|
CG
|
D:ASP181
|
3.0
|
20.7
|
1.0
|
|
C
|
D:ILE183
|
3.4
|
8.3
|
1.0
|
|
CD
|
D:GLU188
|
3.5
|
13.1
|
1.0
|
|
CG
|
D:ASP177
|
3.6
|
21.3
|
1.0
|
|
O
|
D:PRO223
|
3.8
|
14.6
|
1.0
|
|
CB
|
D:ASP179
|
4.0
|
38.3
|
1.0
|
|
CA
|
D:CA737
|
4.0
|
18.9
|
1.0
|
|
CA
|
D:PRO223
|
4.1
|
11.3
|
1.0
|
|
OD2
|
D:ASP177
|
4.2
|
20.6
|
1.0
|
|
OE1
|
D:GLU188
|
4.2
|
13.3
|
1.0
|
|
CB
|
D:ILE183
|
4.2
|
9.6
|
1.0
|
|
CA
|
D:ILE183
|
4.2
|
7.8
|
1.0
|
|
N
|
D:ILE183
|
4.2
|
11.1
|
1.0
|
|
OD1
|
D:ASP185
|
4.2
|
55.9
|
1.0
|
|
CB
|
D:GLU188
|
4.3
|
16.5
|
1.0
|
|
C
|
D:PRO223
|
4.3
|
13.3
|
1.0
|
|
C
|
D:PRO184
|
4.4
|
21.2
|
1.0
|
|
CB
|
D:ASP181
|
4.4
|
20.5
|
1.0
|
|
CG2
|
D:ILE183
|
4.4
|
10.6
|
1.0
|
|
CG
|
D:GLU188
|
4.4
|
14.3
|
1.0
|
|
N
|
D:ASP185
|
4.4
|
9.6
|
1.0
|
|
N
|
D:PRO184
|
4.4
|
17.9
|
1.0
|
|
N
|
D:ASP179
|
4.5
|
60.5
|
1.0
|
|
N
|
D:ASP181
|
4.5
|
22.6
|
1.0
|
|
CA
|
D:PRO184
|
4.6
|
19.1
|
1.0
|
|
CA
|
D:ASP177
|
4.7
|
39.3
|
1.0
|
|
O
|
D:PRO184
|
4.7
|
20.8
|
1.0
|
|
CB
|
D:ASP177
|
4.7
|
24.4
|
1.0
|
|
CA
|
D:ASP179
|
4.7
|
54.9
|
1.0
|
|
CB
|
D:PRO223
|
4.7
|
35.8
|
1.0
|
|
N
|
D:GLY182
|
4.8
|
38.5
|
1.0
|
|
N
|
D:ASN180
|
4.8
|
43.0
|
1.0
|
|
CA
|
D:ASP185
|
4.8
|
12.6
|
1.0
|
|
O
|
D:SER222
|
4.8
|
6.2
|
1.0
|
|
CA
|
D:ASP181
|
5.0
|
18.8
|
1.0
|
|
N
|
D:ARG178
|
5.0
|
58.5
|
1.0
|
|
C
|
D:ASP177
|
5.0
|
37.2
|
1.0
|
|
Calcium binding site 8 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 8 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca737
b:18.9
occ:1.00
|
O
|
D:LYS225
|
2.0
|
64.4
|
1.0
|
|
OE1
|
D:GLU188
|
2.3
|
13.3
|
1.0
|
|
O
|
D:SER222
|
2.3
|
6.2
|
1.0
|
|
OD2
|
D:ASP179
|
2.4
|
37.7
|
1.0
|
|
OD2
|
D:ASP181
|
2.5
|
20.9
|
1.0
|
|
OD2
|
D:ASP235
|
2.8
|
38.6
|
1.0
|
|
CD
|
D:GLU188
|
3.0
|
13.1
|
1.0
|
|
CG
|
D:ASP179
|
3.1
|
37.9
|
1.0
|
|
C
|
D:LYS225
|
3.2
|
64.1
|
1.0
|
|
OE2
|
D:GLU188
|
3.3
|
13.5
|
1.0
|
|
CB
|
D:ASP179
|
3.4
|
38.3
|
1.0
|
|
C
|
D:SER222
|
3.5
|
6.9
|
1.0
|
|
CG
|
D:ASP181
|
3.7
|
20.7
|
1.0
|
|
N
|
D:LYS225
|
3.7
|
61.6
|
1.0
|
|
O
|
D:TRP226
|
3.9
|
52.8
|
1.0
|
|
CG
|
D:ASP235
|
3.9
|
36.7
|
1.0
|
|
CA
|
D:CA736
|
4.0
|
33.7
|
1.0
|
|
OD1
|
D:ASP179
|
4.0
|
38.9
|
1.0
|
|
CA
|
D:LYS225
|
4.0
|
63.9
|
1.0
|
|
C
|
D:PRO223
|
4.0
|
13.3
|
1.0
|
|
CA
|
D:PRO223
|
4.1
|
11.3
|
1.0
|
|
CG
|
D:GLU188
|
4.1
|
14.3
|
1.0
|
|
N
|
D:TRP226
|
4.2
|
54.8
|
1.0
|
|
O
|
D:PRO223
|
4.2
|
14.6
|
1.0
|
|
N
|
D:PRO223
|
4.2
|
10.4
|
1.0
|
|
C
|
D:TRP226
|
4.3
|
52.6
|
1.0
|
|
CA
|
D:TRP226
|
4.4
|
53.9
|
1.0
|
|
CB
|
D:ASP181
|
4.4
|
20.5
|
1.0
|
|
N
|
D:GLU224
|
4.5
|
6.3
|
1.0
|
|
CB
|
D:ASP235
|
4.5
|
32.9
|
1.0
|
|
OG1
|
D:THR228
|
4.6
|
16.8
|
1.0
|
|
CA
|
D:SER222
|
4.6
|
7.1
|
1.0
|
|
OD1
|
D:ASP181
|
4.7
|
20.0
|
1.0
|
|
CB
|
D:LYS225
|
4.7
|
45.8
|
1.0
|
|
N
|
D:SER222
|
4.7
|
7.7
|
1.0
|
|
C
|
D:GLU224
|
4.7
|
12.7
|
1.0
|
|
OG
|
D:SER221
|
5.0
|
12.3
|
1.0
|
|
OD1
|
D:ASP235
|
5.0
|
37.9
|
1.0
|
|
CA
|
D:ASP179
|
5.0
|
54.9
|
1.0
|
|
Calcium binding site 9 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 9 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca736
b:33.7
occ:1.00
|
OD1
|
E:ASP179
|
2.2
|
38.9
|
1.0
|
|
OD2
|
E:ASP179
|
2.2
|
37.7
|
1.0
|
|
O
|
E:ILE183
|
2.2
|
8.1
|
1.0
|
|
OE2
|
E:GLU188
|
2.4
|
13.5
|
1.0
|
|
OD1
|
E:ASP177
|
2.4
|
19.9
|
1.0
|
|
CG
|
E:ASP179
|
2.5
|
37.9
|
1.0
|
|
OD2
|
E:ASP181
|
2.7
|
20.9
|
1.0
|
|
OD1
|
E:ASP181
|
2.7
|
20.0
|
1.0
|
|
CG
|
E:ASP181
|
3.0
|
20.7
|
1.0
|
|
C
|
E:ILE183
|
3.4
|
8.3
|
1.0
|
|
CD
|
E:GLU188
|
3.5
|
13.1
|
1.0
|
|
CG
|
E:ASP177
|
3.6
|
21.3
|
1.0
|
|
O
|
E:PRO223
|
3.8
|
14.6
|
1.0
|
|
CB
|
E:ASP179
|
4.0
|
38.3
|
1.0
|
|
CA
|
E:CA737
|
4.0
|
18.9
|
1.0
|
|
CA
|
E:PRO223
|
4.1
|
11.3
|
1.0
|
|
OD2
|
E:ASP177
|
4.2
|
20.6
|
1.0
|
|
OE1
|
E:GLU188
|
4.2
|
13.3
|
1.0
|
|
CB
|
E:ILE183
|
4.2
|
9.6
|
1.0
|
|
CA
|
E:ILE183
|
4.2
|
7.8
|
1.0
|
|
N
|
E:ILE183
|
4.2
|
11.1
|
1.0
|
|
OD1
|
E:ASP185
|
4.2
|
55.9
|
1.0
|
|
CB
|
E:GLU188
|
4.3
|
16.5
|
1.0
|
|
C
|
E:PRO223
|
4.3
|
13.3
|
1.0
|
|
C
|
E:PRO184
|
4.4
|
21.2
|
1.0
|
|
CB
|
E:ASP181
|
4.4
|
20.5
|
1.0
|
|
CG2
|
E:ILE183
|
4.4
|
10.6
|
1.0
|
|
CG
|
E:GLU188
|
4.4
|
14.3
|
1.0
|
|
N
|
E:ASP185
|
4.4
|
9.6
|
1.0
|
|
N
|
E:PRO184
|
4.4
|
17.9
|
1.0
|
|
N
|
E:ASP179
|
4.5
|
60.5
|
1.0
|
|
N
|
E:ASP181
|
4.5
|
22.6
|
1.0
|
|
CA
|
E:PRO184
|
4.6
|
19.1
|
1.0
|
|
CA
|
E:ASP177
|
4.7
|
39.3
|
1.0
|
|
O
|
E:PRO184
|
4.7
|
20.8
|
1.0
|
|
CB
|
E:ASP177
|
4.7
|
24.4
|
1.0
|
|
CA
|
E:ASP179
|
4.7
|
54.9
|
1.0
|
|
CB
|
E:PRO223
|
4.7
|
35.8
|
1.0
|
|
N
|
E:GLY182
|
4.8
|
38.5
|
1.0
|
|
N
|
E:ASN180
|
4.8
|
43.0
|
1.0
|
|
CA
|
E:ASP185
|
4.8
|
12.6
|
1.0
|
|
O
|
E:SER222
|
4.8
|
6.2
|
1.0
|
|
CA
|
E:ASP181
|
5.0
|
18.8
|
1.0
|
|
N
|
E:ARG178
|
5.0
|
58.5
|
1.0
|
|
C
|
E:ASP177
|
5.0
|
37.2
|
1.0
|
|
Calcium binding site 10 out
of 28 in 1tzo
Go back to
Calcium Binding Sites List in 1tzo
Calcium binding site 10 out
of 28 in the Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca737
b:18.9
occ:1.00
|
O
|
E:LYS225
|
2.0
|
64.4
|
1.0
|
|
OE1
|
E:GLU188
|
2.3
|
13.3
|
1.0
|
|
O
|
E:SER222
|
2.3
|
6.2
|
1.0
|
|
OD2
|
E:ASP179
|
2.4
|
37.7
|
1.0
|
|
OD2
|
E:ASP181
|
2.5
|
20.9
|
1.0
|
|
OD2
|
E:ASP235
|
2.8
|
38.6
|
1.0
|
|
CD
|
E:GLU188
|
3.0
|
13.1
|
1.0
|
|
CG
|
E:ASP179
|
3.1
|
37.9
|
1.0
|
|
C
|
E:LYS225
|
3.2
|
64.1
|
1.0
|
|
OE2
|
E:GLU188
|
3.3
|
13.5
|
1.0
|
|
CB
|
E:ASP179
|
3.4
|
38.3
|
1.0
|
|
C
|
E:SER222
|
3.5
|
6.9
|
1.0
|
|
CG
|
E:ASP181
|
3.7
|
20.7
|
1.0
|
|
N
|
E:LYS225
|
3.7
|
61.6
|
1.0
|
|
O
|
E:TRP226
|
3.9
|
52.8
|
1.0
|
|
CG
|
E:ASP235
|
3.9
|
36.7
|
1.0
|
|
CA
|
E:CA736
|
4.0
|
33.7
|
1.0
|
|
OD1
|
E:ASP179
|
4.0
|
38.9
|
1.0
|
|
CA
|
E:LYS225
|
4.0
|
63.9
|
1.0
|
|
C
|
E:PRO223
|
4.0
|
13.3
|
1.0
|
|
CA
|
E:PRO223
|
4.1
|
11.3
|
1.0
|
|
CG
|
E:GLU188
|
4.1
|
14.3
|
1.0
|
|
N
|
E:TRP226
|
4.2
|
54.8
|
1.0
|
|
O
|
E:PRO223
|
4.2
|
14.6
|
1.0
|
|
N
|
E:PRO223
|
4.2
|
10.4
|
1.0
|
|
C
|
E:TRP226
|
4.3
|
52.6
|
1.0
|
|
CA
|
E:TRP226
|
4.4
|
53.9
|
1.0
|
|
CB
|
E:ASP181
|
4.4
|
20.5
|
1.0
|
|
N
|
E:GLU224
|
4.5
|
6.3
|
1.0
|
|
CB
|
E:ASP235
|
4.5
|
32.9
|
1.0
|
|
OG1
|
E:THR228
|
4.6
|
16.8
|
1.0
|
|
CA
|
E:SER222
|
4.6
|
7.1
|
1.0
|
|
OD1
|
E:ASP181
|
4.7
|
20.0
|
1.0
|
|
CB
|
E:LYS225
|
4.7
|
45.8
|
1.0
|
|
N
|
E:SER222
|
4.7
|
7.7
|
1.0
|
|
C
|
E:GLU224
|
4.7
|
12.7
|
1.0
|
|
OG
|
E:SER221
|
5.0
|
12.3
|
1.0
|
|
OD1
|
E:ASP235
|
5.0
|
37.9
|
1.0
|
|
CA
|
E:ASP179
|
5.0
|
54.9
|
1.0
|
|
Reference:
D.B.Lacy,
D.J.Wigelsworth,
R.A.Melnyk,
S.C.Harrison,
R.J.Collier.
Structure of Heptameric Protective Antigen Bound to An Anthrax Toxin Receptor: A Role For Receptor in pH-Dependent Pore Formation Proc.Natl.Acad.Sci.Usa V. 101 13147 2004.
ISSN: ISSN 0027-8424
PubMed: 15326297
DOI: 10.1073/PNAS.0405405101
Page generated: Thu Jul 11 23:13:46 2024
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