Atomistry » Calcium » PDB 1ukg-1ux6 » 1uvn
Atomistry »
  Calcium »
    PDB 1ukg-1ux6 »
      1uvn »

Calcium in PDB 1uvn: The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex

Enzymatic activity of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex

All present enzymatic activity of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex:
2.7.7.48;

Protein crystallography data

The structure of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex, PDB code: 1uvn was solved by P.S.Salgado, E.V.Makeyev, S.Butcher, D.Bamford, D.I.Stuart, J.M.Grimes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.93 / 3.00
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 105.504, 92.134, 140.755, 90.00, 101.01, 90.00
R / Rfree (%) 23.4 / 25.7

Other elements in 1uvn:

The structure of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex also contains other interesting chemical elements:

Manganese (Mn) 3 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex (pdb code 1uvn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 6 binding sites of Calcium where determined in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex, PDB code: 1uvn:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6;

Calcium binding site 1 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 1 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1667

b:0.1
occ:1.00
 O2B A:GTP1665 2.7 0.3 1.0
O1A A:GTP1665 2.8 0.3 1.0
OH A:TYR630 3.0 0.9 1.0
O2G A:GTP1665 3.2 0.6 1.0
NH2 A:ARG204 3.3 89.3 1.0
O A:HOH2050 3.7 44.0 1.0
CZ A:TYR630 3.7 0.2 1.0
CE2 A:TYR630 4.0 0.1 1.0
PB A:GTP1665 4.0 0.3 1.0
PA A:GTP1665 4.1 0.3 1.0
N7 A:GTP1665 4.1 0.3 1.0
OE1 A:GLU529 4.2 79.6 1.0
C8 A:GTP1665 4.3 0.3 1.0
NE2 A:GLN206 4.4 97.1 1.0
O3A A:GTP1665 4.4 0.3 1.0
CZ A:ARG204 4.4 87.0 1.0
PG A:GTP1665 4.5 0.3 1.0
CE1 A:TYR630 4.6 0.3 1.0
O3B A:GTP1665 4.7 0.3 1.0
O5' A:GTP1665 4.7 0.2 1.0
NH1 A:ARG204 4.7 88.3 1.0

Calcium binding site 2 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 2 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1668

b:62.3
occ:1.00
 O A:VAL325 2.7 73.7 1.0
O1A A:GTP1666 2.8 0.5 1.0
OD2 A:ASP453 2.9 74.7 1.0
O2B A:GTP1666 3.0 93.0 1.0
O2G A:GTP1666 3.0 0.9 1.0
O3B A:GTP1666 3.3 96.4 1.0
OD1 A:ASP453 3.4 66.1 1.0
CG A:ASP453 3.4 69.0 1.0
PB A:GTP1666 3.5 94.4 1.0
PA A:GTP1666 3.6 0.6 1.0
O3A A:GTP1666 3.6 97.8 1.0
O5' A:GTP1666 3.8 0.7 1.0
PG A:GTP1666 3.8 0.9 1.0
C A:VAL325 3.8 66.9 1.0
O A:HOH2023 4.1 59.1 1.0
CA A:SER326 4.3 66.1 1.0
OD1 A:ASP324 4.4 88.1 1.0
N A:ASP327 4.6 59.5 1.0
CB A:HIS328 4.6 45.4 1.0
N A:SER326 4.6 67.0 1.0
O1G A:GTP1666 4.7 0.9 1.0
CB A:VAL325 4.7 62.2 1.0
CA A:VAL325 4.7 64.5 1.0
N A:VAL325 4.8 65.0 1.0
CB A:ASP453 4.8 67.8 1.0
N A:HIS328 4.8 47.6 1.0
C A:SER326 4.9 64.8 1.0
O3G A:GTP1666 5.0 97.2 1.0
C5' A:GTP1666 5.0 96.3 1.0

Calcium binding site 3 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 3 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca1667

b:0.1
occ:1.00
 O2B C:GTP1665 2.7 0.3 1.0
O1A C:GTP1665 2.8 0.3 1.0
OH C:TYR630 3.0 0.9 1.0
O2G C:GTP1665 3.2 0.6 1.0
NH2 C:ARG204 3.3 89.3 1.0
O C:HOH2048 3.7 44.0 1.0
CZ C:TYR630 3.7 0.2 1.0
CE2 C:TYR630 4.0 0.1 1.0
PB C:GTP1665 4.0 0.3 1.0
PA C:GTP1665 4.1 0.3 1.0
N7 C:GTP1665 4.1 0.3 1.0
OE1 C:GLU529 4.2 79.6 1.0
C8 C:GTP1665 4.3 0.3 1.0
NE2 C:GLN206 4.4 97.1 1.0
O3A C:GTP1665 4.4 0.3 1.0
CZ C:ARG204 4.4 87.0 1.0
PG C:GTP1665 4.5 0.3 1.0
CE1 C:TYR630 4.6 0.3 1.0
O3B C:GTP1665 4.7 0.3 1.0
O5' C:GTP1665 4.7 0.2 1.0
NH1 C:ARG204 4.7 88.3 1.0

Calcium binding site 4 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 4 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca1668

b:62.3
occ:1.00
 O C:VAL325 2.7 73.7 1.0
O1A C:GTP1666 2.8 0.5 1.0
OD2 C:ASP453 2.9 74.7 1.0
O2B C:GTP1666 3.0 93.0 1.0
O2G C:GTP1666 3.0 0.9 1.0
O3B C:GTP1666 3.3 96.4 1.0
OD1 C:ASP453 3.4 66.1 1.0
CG C:ASP453 3.4 69.0 1.0
PB C:GTP1666 3.5 94.4 1.0
PA C:GTP1666 3.6 0.6 1.0
O3A C:GTP1666 3.6 97.8 1.0
O5' C:GTP1666 3.8 0.7 1.0
PG C:GTP1666 3.8 0.9 1.0
C C:VAL325 3.8 66.9 1.0
O C:HOH2023 4.1 59.1 1.0
CA C:SER326 4.3 66.1 1.0
OD1 C:ASP324 4.4 88.1 1.0
N C:ASP327 4.6 59.5 1.0
N C:SER326 4.6 67.0 1.0
CB C:HIS328 4.6 45.4 1.0
O1G C:GTP1666 4.7 0.9 1.0
CB C:VAL325 4.7 62.2 1.0
CA C:VAL325 4.7 64.5 1.0
N C:VAL325 4.8 65.0 1.0
CB C:ASP453 4.8 67.8 1.0
N C:HIS328 4.8 47.6 1.0
C C:SER326 4.9 64.8 1.0
O3G C:GTP1666 5.0 97.2 1.0
C5' C:GTP1666 5.0 96.3 1.0

Calcium binding site 5 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 5 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Ca1667

b:0.1
occ:1.00
 O2B E:GTP1665 2.7 0.3 1.0
O1A E:GTP1665 2.8 0.3 1.0
OH E:TYR630 3.0 0.9 1.0
O2G E:GTP1665 3.2 0.6 1.0
NH2 E:ARG204 3.3 89.3 1.0
O E:HOH2049 3.7 44.0 1.0
CZ E:TYR630 3.7 0.2 1.0
CE2 E:TYR630 4.0 0.1 1.0
PB E:GTP1665 4.0 0.3 1.0
PA E:GTP1665 4.1 0.3 1.0
N7 E:GTP1665 4.1 0.3 1.0
OE1 E:GLU529 4.2 79.6 1.0
C8 E:GTP1665 4.3 0.3 1.0
NE2 E:GLN206 4.4 97.1 1.0
O3A E:GTP1665 4.4 0.3 1.0
CZ E:ARG204 4.4 87.0 1.0
PG E:GTP1665 4.5 0.3 1.0
CE1 E:TYR630 4.6 0.3 1.0
O3B E:GTP1665 4.7 0.3 1.0
O5' E:GTP1665 4.7 0.2 1.0
NH1 E:ARG204 4.7 88.3 1.0

Calcium binding site 6 out of 6 in 1uvn

Go back to Calcium Binding Sites List in 1uvn
Calcium binding site 6 out of 6 in the The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of The Structural Basis For Rna Specificity and CA2 Inhibition of An Rna- Dependent Rna Polymerase PHI6P2 CA2+ Inhibition Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Ca1668

b:62.3
occ:1.00
 O E:VAL325 2.7 73.7 1.0
O1A E:GTP1666 2.8 0.5 1.0
OD2 E:ASP453 2.9 74.7 1.0
O2B E:GTP1666 3.0 93.0 1.0
O2G E:GTP1666 3.0 0.9 1.0
O3B E:GTP1666 3.3 96.4 1.0
OD1 E:ASP453 3.4 66.1 1.0
CG E:ASP453 3.4 69.0 1.0
PB E:GTP1666 3.5 94.4 1.0
PA E:GTP1666 3.6 0.6 1.0
O3A E:GTP1666 3.6 97.8 1.0
O5' E:GTP1666 3.8 0.7 1.0
PG E:GTP1666 3.8 0.9 1.0
C E:VAL325 3.8 66.9 1.0
O E:HOH2023 4.1 59.1 1.0
CA E:SER326 4.3 66.1 1.0
OD1 E:ASP324 4.4 88.1 1.0
N E:ASP327 4.6 59.5 1.0
CB E:HIS328 4.6 45.4 1.0
N E:SER326 4.6 67.0 1.0
O1G E:GTP1666 4.7 0.9 1.0
CB E:VAL325 4.7 62.2 1.0
CA E:VAL325 4.7 64.5 1.0
N E:VAL325 4.8 65.0 1.0
CB E:ASP453 4.8 67.8 1.0
N E:HIS328 4.8 47.6 1.0
C E:SER326 4.9 64.8 1.0
O3G E:GTP1666 5.0 97.2 1.0
C5' E:GTP1666 5.0 96.3 1.0

Reference:

P.S.Salgado, E.V.Makeyev, S.J.Butcher, D.H.Bamford, D.I.Stuart, J.M.Grimes. The Structural Basis For Rna Specificity and CA2+ Inhibition of An Rna-Dependent Rna Polymerase. Structure V. 12 307 2004.
ISSN: ISSN 0969-2126
PubMed: 14962391
DOI: 10.1016/J.STR.2004.01.012
Page generated: Thu Jul 11 23:41:02 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy