Calcium in PDB 1v3c: Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC

All present enzymatic activity of Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC:
3.2.1.18;

The structure of Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC, PDB code: 1v3c was solved by M.C.Lawrence, N.A.Borg, V.A.Streltsov, P.A.Pilling, V.C.Epa, J.N.Varghese, J.L.Mckimm-Breschkin, P.M.Colman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.50 / 2.30
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	218.625, 218.625, 109.871, 90.00, 90.00, 120.00
R / Rfree (%)	17.6 / 22.2

The binding sites of Calcium atom in the Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC (pdb code 1v3c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC, PDB code: 1v3c:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:39.9 occ:1.00 O A:ALA316 2.3 24.8 1.0 O A:ASP279 2.3 32.6 1.0 O A:SER282 2.3 36.6 1.0 O A:GLY284 2.4 29.7 1.0 OD1 A:ASP279 2.5 28.7 1.0 OG A:SER282 2.9 46.0 1.0 C A:ASP279 3.3 32.1 1.0 C A:SER282 3.5 33.7 1.0 C A:ALA316 3.5 24.6 1.0 CG A:ASP279 3.6 34.8 1.0 CA A:ASP279 3.7 32.3 1.0 C A:GLY284 3.7 29.4 1.0 CB A:SER282 4.1 38.0 1.0 O A:PRO283 4.1 26.1 1.0 CA A:SER282 4.1 36.5 1.0 C A:PRO283 4.2 28.1 1.0 CB A:ASP279 4.3 31.4 1.0 CA A:ILE285 4.3 23.8 1.0 N A:SER282 4.3 33.9 1.0 CA A:ALA316 4.3 21.9 1.0 O A:HOH3798 4.4 34.2 1.0 N A:TYR280 4.5 29.6 1.0 N A:GLY284 4.5 28.9 1.0 N A:ALA317 4.5 25.0 1.0 N A:ILE285 4.5 26.0 1.0 N A:PRO283 4.5 34.8 1.0 OD2 A:ASP279 4.6 35.5 1.0 CA A:GLY284 4.6 27.6 1.0 CA A:ALA317 4.7 24.8 1.0 O A:SER278 4.7 40.6 1.0 OE2 A:GLU286 4.8 34.0 1.0 CA A:PRO283 4.8 31.7 1.0 C A:ILE285 4.8 25.4 1.0 CB A:ALA316 4.9 19.2 1.0 N A:GLU286 4.9 22.8 1.0 CA A:TYR280 4.9 29.1 1.0 N A:ASP279 4.9 35.0 1.0 CB A:ALA317 5.0 21.0 1.0

Calcium binding site 2 out of 2 in the Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the Hemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III: Complex with NEU5AC within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca2001 b:31.6 occ:1.00 O B:ALA316 2.3 28.3 1.0 O B:HOH5285 2.3 28.1 1.0 O B:GLY284 2.3 23.9 1.0 O B:SER282 2.3 31.2 1.0 O B:ASP279 2.4 21.1 1.0 OD1 B:ASP279 2.6 27.9 1.0 OG B:SER282 2.8 35.1 1.0 C B:SER282 3.4 33.7 1.0 C B:ASP279 3.4 26.7 1.0 C B:ALA316 3.5 29.5 1.0 C B:GLY284 3.5 28.6 1.0 CG B:ASP279 3.7 34.6 1.0 CA B:ASP279 3.9 29.1 1.0 CB B:SER282 3.9 30.3 1.0 O B:PRO283 4.0 34.6 1.0 CA B:SER282 4.0 28.8 1.0 C B:PRO283 4.1 34.5 1.0 O B:HOH5470 4.2 35.6 1.0 CA B:ALA316 4.2 27.9 1.0 N B:SER282 4.2 27.2 1.0 CA B:ILE285 4.2 23.7 1.0 N B:ILE285 4.3 27.3 1.0 N B:GLY284 4.4 31.1 1.0 CB B:ASP279 4.4 33.5 1.0 N B:PRO283 4.5 36.8 1.0 N B:ALA317 4.5 29.0 1.0 CA B:GLY284 4.5 27.6 1.0 N B:TYR280 4.6 24.4 1.0 OD2 B:ASP279 4.6 40.4 1.0 O B:HOH5569 4.6 47.3 1.0 CA B:PRO283 4.7 34.5 1.0 CA B:ALA317 4.8 23.4 1.0 C B:ILE285 4.8 24.8 1.0 CB B:ALA316 4.8 25.4 1.0 CA B:TYR280 4.9 24.8 1.0 OE2 B:GLU286 4.9 29.8 1.0 N B:GLU286 4.9 21.4 1.0

M.C.Lawrence, N.A.Borg, V.A.Streltsov, P.A.Pilling, V.C.Epa, J.N.Varghese, J.L.Mckimm-Breschkin, P.M.Colman. Structure of the Haemagglutinin-Neuraminidase From Human Parainfluenza Virus Type III J.Mol.Biol. V. 335 1343 2004.
ISSN: ISSN 0022-2836
PubMed: 14729348
DOI: 10.1016/J.JMB.2003.11.032