Calcium in PDB 1w7x: FACTOR7 - 413 Complex

All present enzymatic activity of FACTOR7 - 413 Complex:
3.4.21.21;

The structure of FACTOR7 - 413 Complex, PDB code: 1w7x was solved by J.Ackermann, L.Alig, D.W.Banner, H.-J.Boehm, K.Groebke-Zbinden, K.Hilpert, T.Lave, H.Kuehne, U.Obst-Sander, M.A.Riederer, M.Stahl, T.B.Tschopp, L.Weber, H.P.Wessel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	73.52 / 1.80
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	95.000, 95.000, 115.850, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 19.5

The binding sites of Calcium atom in the FACTOR7 - 413 Complex (pdb code 1w7x). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the FACTOR7 - 413 Complex, PDB code: 1w7x:

Calcium binding site 1 out of 1 in the FACTOR7 - 413 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of FACTOR7 - 413 Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca1260 b:25.6 occ:1.00 O H:GLU75 2.3 21.0 1.0 OE1 H:GLU70 2.4 12.0 1.0 O H:HOH2176 2.5 22.6 1.0 OE2 H:GLU80 2.5 14.2 1.0 O H:ASP72 2.6 13.4 1.0 O H:HOH2166 2.7 21.6 1.0 CD H:GLU70 3.4 13.9 1.0 C H:GLU75 3.5 18.4 1.0 CD H:GLU80 3.6 14.6 1.0 C H:ASP72 3.6 13.6 1.0 OE2 H:GLU70 3.7 15.5 1.0 O H:HOH2163 3.8 14.3 1.0 CG H:GLU80 3.9 12.4 1.0 N H:ASP72 3.9 13.0 1.0 O H:HOH2191 4.1 33.3 1.0 CA H:ASP72 4.3 13.9 1.0 CA H:HIS76 4.3 16.4 1.0 N H:HIS71 4.3 11.3 1.0 N H:HIS76 4.3 17.3 1.0 CG H:GLU75 4.4 22.4 1.0 N H:GLU75 4.5 17.2 1.0 N H:ASP77 4.5 15.4 1.0 N H:LEU73 4.5 14.2 1.0 CA H:GLU75 4.5 18.7 1.0 O H:HOH2195 4.7 25.1 1.0 OE1 H:GLU80 4.7 14.2 1.0 CB H:ASP72 4.7 14.4 1.0 CA H:LEU73 4.7 15.0 1.0 CG H:GLU70 4.7 12.9 1.0 O H:HOH2184 4.8 22.4 1.0 C H:HIS76 4.8 16.6 1.0 C H:HIS71 4.9 12.0 1.0 OD1 H:ASP77 4.9 15.1 1.0 CG H:ASP77 4.9 14.9 1.0 CA H:GLU70 5.0 11.2 1.0

K.G.Zbinden, U.Obst-Sander, K.Hilpert, H.Kuhne, D.W.Banner, H.J.Bohm, M.Stahl, J.Ackermann, L.Alig, L.Weber, H.P.Wessel, M.A.Riederer, T.B.Tschopp, T.Lave. Selective and Orally Bioavailable Phenylglycine Tissue Factor/Factor Viia Inhibitors. Bioorg.Med.Chem.Lett. V. 15 5344 2005.
ISSN: ISSN 0960-894X
PubMed: 16213138
DOI: 10.1016/J.BMCL.2005.04.079